NO20023921D0 - Derivater av thiazepinylhydroksamisk syre som inhibitorer av matriks metalloproteinase - Google Patents
Derivater av thiazepinylhydroksamisk syre som inhibitorer av matriks metalloproteinaseInfo
- Publication number
- NO20023921D0 NO20023921D0 NO20023921A NO20023921A NO20023921D0 NO 20023921 D0 NO20023921 D0 NO 20023921D0 NO 20023921 A NO20023921 A NO 20023921A NO 20023921 A NO20023921 A NO 20023921A NO 20023921 D0 NO20023921 D0 NO 20023921D0
- Authority
- NO
- Norway
- Prior art keywords
- thiazepinyl
- inhibitors
- acid derivatives
- hydroxamic acid
- matrix metalloproteinase
- Prior art date
Links
- 102000002274 Matrix Metalloproteinases Human genes 0.000 title 1
- 108010000684 Matrix Metalloproteinases Proteins 0.000 title 1
- -1 Thiazepinyl hydroxamic Chemical compound 0.000 title 1
- 239000002253 acid Substances 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
- C07D281/02—Seven-membered rings
- C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
- C07D281/06—Seven-membered rings having the hetero atoms in positions 1 and 4 not condensed with other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Dermatology (AREA)
- Pain & Pain Management (AREA)
- Virology (AREA)
- Heart & Thoracic Surgery (AREA)
- Neurosurgery (AREA)
- Transplantation (AREA)
- Tropical Medicine & Parasitology (AREA)
- AIDS & HIV (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Molecular Biology (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AUPQ5751A AUPQ575100A0 (en) | 2000-02-21 | 2000-02-21 | Cyclic compound |
| AUPQ8603A AUPQ860300A0 (en) | 2000-07-06 | 2000-07-06 | Cyclic compound |
| PCT/JP2001/001206 WO2001060808A1 (en) | 2000-02-21 | 2001-02-20 | Thiazepinyl hydroxamic acid derivatives as matrix metalloproteinase inhibitors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO20023921D0 true NO20023921D0 (no) | 2002-08-19 |
| NO20023921L NO20023921L (no) | 2002-10-11 |
Family
ID=25646264
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20023921A NO20023921L (no) | 2000-02-21 | 2002-08-19 | Derivater av thiazepinylhydroksamisk syre som inhibitorer av matriks metalloproteinase |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US6967197B2 (no) |
| EP (1) | EP1259499A1 (no) |
| JP (1) | JP2003523337A (no) |
| KR (1) | KR20030000029A (no) |
| CN (1) | CN1188404C (no) |
| AR (1) | AR027952A1 (no) |
| BR (1) | BR0108791A (no) |
| CA (1) | CA2400862A1 (no) |
| HU (1) | HUP0204501A2 (no) |
| IL (1) | IL151197A0 (no) |
| MX (1) | MXPA02008175A (no) |
| NO (1) | NO20023921L (no) |
| PL (1) | PL357084A1 (no) |
| WO (1) | WO2001060808A1 (no) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2002226464A (ja) * | 2001-01-30 | 2002-08-14 | Sumitomo Pharmaceut Co Ltd | トリアリール類縁体およびその利用 |
| AUPR755501A0 (en) * | 2001-09-07 | 2001-09-27 | Fujisawa Pharmaceutical Co., Ltd. | Cyclic compound |
| WO2003031431A1 (en) | 2001-10-09 | 2003-04-17 | Bristol-Myers Squibb Company | Cyclic sulfone derivatives as inhibitors of matrix metalloproteinases and/or tnf-$g(a) converting enzyme (tace) |
| US8507277B2 (en) | 2003-10-24 | 2013-08-13 | Gencia Corporation | Nonviral vectors for delivering polynucleotides |
| US8133733B2 (en) | 2003-10-24 | 2012-03-13 | Gencia Corporation | Nonviral vectors for delivering polynucleotides to target tissues |
| US20090123468A1 (en) | 2003-10-24 | 2009-05-14 | Gencia Corporation | Transducible polypeptides for modifying metabolism |
| US8039587B2 (en) | 2003-10-24 | 2011-10-18 | Gencia Corporation | Methods and compositions for delivering polynucleotides |
| US8062891B2 (en) | 2003-10-24 | 2011-11-22 | Gencia Corporation | Nonviral vectors for delivering polynucleotides to plants |
| KR100685222B1 (ko) * | 2004-12-03 | 2007-02-22 | 우경건설 주식회사 | 이중 콘크리트 구조물 |
| US20100028439A1 (en) * | 2005-05-23 | 2010-02-04 | Elan Pharma International Limited | Nanoparticulate stabilized anti-hypertensive compositions |
| CN104926707B (zh) * | 2015-05-12 | 2017-10-27 | 江苏福瑞生物医药有限公司 | 一种药物中间体的合成方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE206073T1 (de) * | 1995-12-29 | 2001-10-15 | Novozymes As | Enzym enthaltende teilchen und flüssiges reinigungsmittelkonzentrat |
| BR9712085A (pt) * | 1996-08-28 | 2000-10-24 | Procter & Gamble | Inibidores de metaloprotease heterocìclicos |
| AU731319B2 (en) * | 1996-08-28 | 2001-03-29 | Procter & Gamble Company, The | Heterocyclic metalloprotease inhibitors |
| JP2001506257A (ja) | 1996-12-17 | 2001-05-15 | 藤沢薬品工業株式会社 | Ｍｍｐまたはｔｎｆ阻害剤としてのピペラジン化合物 |
-
2001
- 2001-02-20 PL PL01357084A patent/PL357084A1/xx not_active Application Discontinuation
- 2001-02-20 BR BR0108791-6A patent/BR0108791A/pt not_active Application Discontinuation
- 2001-02-20 MX MXPA02008175A patent/MXPA02008175A/es unknown
- 2001-02-20 CA CA002400862A patent/CA2400862A1/en not_active Abandoned
- 2001-02-20 IL IL15119701A patent/IL151197A0/xx unknown
- 2001-02-20 EP EP01906142A patent/EP1259499A1/en not_active Withdrawn
- 2001-02-20 KR KR1020027010721A patent/KR20030000029A/ko not_active Application Discontinuation
- 2001-02-20 JP JP2001560193A patent/JP2003523337A/ja not_active Withdrawn
- 2001-02-20 WO PCT/JP2001/001206 patent/WO2001060808A1/en not_active Application Discontinuation
- 2001-02-20 US US10/203,627 patent/US6967197B2/en not_active Expired - Fee Related
- 2001-02-20 HU HU0204501A patent/HUP0204501A2/hu unknown
- 2001-02-20 CN CNB018082432A patent/CN1188404C/zh not_active Expired - Fee Related
- 2001-02-21 AR ARP010100781A patent/AR027952A1/es unknown
-
2002
- 2002-08-19 NO NO20023921A patent/NO20023921L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| CA2400862A1 (en) | 2001-08-23 |
| WO2001060808A1 (en) | 2001-08-23 |
| EP1259499A1 (en) | 2002-11-27 |
| CN1425010A (zh) | 2003-06-18 |
| MXPA02008175A (es) | 2003-05-23 |
| AR027952A1 (es) | 2003-04-16 |
| JP2003523337A (ja) | 2003-08-05 |
| KR20030000029A (ko) | 2003-01-03 |
| PL357084A1 (en) | 2004-07-12 |
| US20030134849A1 (en) | 2003-07-17 |
| NO20023921L (no) | 2002-10-11 |
| CN1188404C (zh) | 2005-02-09 |
| HUP0204501A2 (hu) | 2003-04-28 |
| BR0108791A (pt) | 2004-04-27 |
| IL151197A0 (en) | 2003-04-10 |
| US6967197B2 (en) | 2005-11-22 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CY2015053I2 (el) | Υδροξαμικα παραγωγα χρησιμα ως αναστολεις δεακετυλασης | |
| NO20010686D0 (no) | Hydroksypipecolathydroksaminsyrederivater som MMP inhibitorer | |
| NO20024402D0 (no) | Cykliske <beta>-aminosyrederivater som inhibitorer av matriksmetalloproteaser og TNF-<alfa> | |
| EE200300362A (et) | PDE4 isosüümide inhibiitoritena kasutatavad tiasolüül-, oksasolüül-, pürrolüül- ja imidasolüülhappeamiidi derivaadid | |
| DK1036062T3 (da) | Hydroxamsyrederivater som matrix metalloprotease (MMP) inhibitorer | |
| SE0701538L (sv) | Azaspiroalkanderivat som hämmare av metalloproteaser | |
| NO20031450L (no) | Fumarsyrederivater som NF-kappa B inhibitorer | |
| NO20015543L (no) | Aromatisk sulfonhydroksamsyre-metalloproteaseinhibitor | |
| NO20031797L (no) | Heteroarylalkylpiperazin-derivater som fettsyreoksidasjonsinhibitorer | |
| DK1347955T3 (da) | Nye mandelsyrederivater og deres anvendelse som throbin-hæmmere | |
| NO20021042L (no) | Benzofenoner som inhibitorer av reverstranskriptaser | |
| EE200100410A (et) | Sulfamaathüdroksaamhappe metalloproteaasi inhibiitor | |
| NO20033742L (no) | Omega-aminoalkylamider av R-2-arylpropionsyrer som inhibitorer av polymofonukle¶re og mononukle¶re cellers kjemotakse | |
| NO20015065L (no) | Pyrazolobenzodiazepiner som CDK2-inhibitorer | |
| NO20026262L (no) | Cyklopentyl-substituerte glutaramidderivater som inhibitorer av nöytral endopeptidase | |
| DE60008548D1 (de) | Hydroxamsäurederivate als matrix-metalloproteinase-inhibitoren | |
| NO20013675L (no) | 2,3,4,5-tetrahydro-1H-[1,4)benzodiazepin-3-hydroksamsyre som matriks-metalloproteinase-inhibitorer | |
| NO20023921D0 (no) | Derivater av thiazepinylhydroksamisk syre som inhibitorer av matriks metalloproteinase | |
| NO20023956D0 (no) | Priperidin- og piperazinsubstituerte N-hydroksyformamider som inhibitorer av metalloproteinaser | |
| DK1147080T3 (da) | Alkynylholdige hydroxamsyreforbindelser som TACE-inhibitorer | |
| NO991994D0 (no) | Substituerte 4-bifenyl-4-hydroksysm°rsyrederivater som matriks-metalloproteaseinhibitorer | |
| NO20024481D0 (no) | Difluorbutyrsyre metalloproteaseinhibitorer | |
| ATE323673T1 (de) | Pyrrolidin-2-carbonsäure-hydrazid-derivate als metalloprotease-inhibitoren | |
| NO20013669L (no) | Reverse hydroksamatinhibitorer av matriks metalloproteinaser | |
| NO20022838L (no) | Saccharinderivater som oralt aktive elastaseinhibitorer |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |