NO20020592L - Fluorenderivater som integrininhibitorer - Google Patents
Fluorenderivater som integrininhibitorerInfo
- Publication number
- NO20020592L NO20020592L NO20020592A NO20020592A NO20020592L NO 20020592 L NO20020592 L NO 20020592L NO 20020592 A NO20020592 A NO 20020592A NO 20020592 A NO20020592 A NO 20020592A NO 20020592 L NO20020592 L NO 20020592L
- Authority
- NO
- Norway
- Prior art keywords
- integrin inhibitors
- fluorine derivatives
- disorders
- nhtv
- arteriosclerosis
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/44—Nitrogen atoms not forming part of a nitro radical
- C07D233/48—Nitrogen atoms not forming part of a nitro radical with acyclic hydrocarbon or substituted acyclic hydrocarbon radicals, attached to said nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
- C07C279/12—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by nitrogen atoms not being part of nitro or nitroso groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/02—Ortho- or ortho- and peri-condensed systems
- C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
- C07C2603/06—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
- C07C2603/10—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Cardiology (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Heart & Thoracic Surgery (AREA)
- Rheumatology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Hospice & Palliative Care (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Oppfinnelsen vedrører forbindelser med formel (I) (D \ NHtV hvor R1, R2, R3, R4, R5, m og n har betydningene angitt i krav l, og deres fysiologisk akseptable salter og solvater, som kan anvendes som integrininhibitorer, spesielt til profylakse og behandling av blodomløps- forstyrrelser, trombose, hjerteinfarkt, koronare forstyrrelser, arterio- sklerose, osteoporose, patologiske prosesser som opprettholdes eller propargeres gjennom angiogenese, samt tumorterapi.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19937394A DE19937394A1 (de) | 1999-08-07 | 1999-08-07 | Fluorenderivate |
PCT/EP2000/007153 WO2001010841A2 (de) | 1999-08-07 | 2000-07-26 | Fluorenderivate als integrin inhibitoren |
Publications (2)
Publication Number | Publication Date |
---|---|
NO20020592D0 NO20020592D0 (no) | 2002-02-06 |
NO20020592L true NO20020592L (no) | 2002-04-04 |
Family
ID=7917613
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20020592A NO20020592L (no) | 1999-08-07 | 2002-02-06 | Fluorenderivater som integrininhibitorer |
Country Status (18)
Country | Link |
---|---|
EP (1) | EP1208088A2 (no) |
JP (1) | JP2003506439A (no) |
KR (1) | KR20020012631A (no) |
CN (1) | CN1368962A (no) |
AR (1) | AR025042A1 (no) |
AU (1) | AU6828600A (no) |
BR (1) | BR0013083A (no) |
CA (1) | CA2380981A1 (no) |
CZ (1) | CZ2002298A3 (no) |
DE (1) | DE19937394A1 (no) |
HK (1) | HK1049006A1 (no) |
HU (1) | HUP0202464A3 (no) |
MX (1) | MXPA02001297A (no) |
NO (1) | NO20020592L (no) |
PL (1) | PL353054A1 (no) |
SK (1) | SK1402002A3 (no) |
WO (1) | WO2001010841A2 (no) |
ZA (1) | ZA200201873B (no) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR101102808B1 (ko) * | 2010-04-13 | 2012-01-05 | 윤태삼 | 라이저 인장 장치 |
US8574899B2 (en) | 2010-12-22 | 2013-11-05 | Vladimir B Serikov | Methods for augmentation collection of placental hematopoietic stem cells and uses thereof |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH04506350A (ja) * | 1989-06-22 | 1992-11-05 | ノバ ファーマスーティカル コーポレイション | 炎症の処置用の医薬組成物及び炎症の処置方法 |
IL113196A0 (en) * | 1994-03-31 | 1995-06-29 | Bristol Myers Squibb Co | Imidazole derivatives and pharmaceutical compositions containing the same |
ATE204857T1 (de) * | 1996-03-29 | 2001-09-15 | Searle & Co | Meta-substituierte phenylenderivate und ihre verwendung als alphavbeta3 intergrin-antagonisten oder inhibitoren |
DE19654483A1 (de) * | 1996-06-28 | 1998-01-02 | Merck Patent Gmbh | Phenylalanin-Derivate |
CA2214931A1 (en) * | 1996-09-26 | 1998-03-26 | Henry Uhlman Bryant | Tetrahydrobenzo-a-fluorene compounds and method of use |
-
1999
- 1999-08-07 DE DE19937394A patent/DE19937394A1/de not_active Withdrawn
-
2000
- 2000-07-26 JP JP2001515308A patent/JP2003506439A/ja active Pending
- 2000-07-26 EP EP00956284A patent/EP1208088A2/de not_active Withdrawn
- 2000-07-26 KR KR1020027000660A patent/KR20020012631A/ko not_active Application Discontinuation
- 2000-07-26 HU HU0202464A patent/HUP0202464A3/hu unknown
- 2000-07-26 AU AU68286/00A patent/AU6828600A/en not_active Abandoned
- 2000-07-26 WO PCT/EP2000/007153 patent/WO2001010841A2/de not_active Application Discontinuation
- 2000-07-26 MX MXPA02001297A patent/MXPA02001297A/es not_active Application Discontinuation
- 2000-07-26 PL PL00353054A patent/PL353054A1/xx unknown
- 2000-07-26 CN CN00811476A patent/CN1368962A/zh active Pending
- 2000-07-26 CA CA002380981A patent/CA2380981A1/en not_active Abandoned
- 2000-07-26 BR BR0013083-4A patent/BR0013083A/pt not_active Application Discontinuation
- 2000-07-26 SK SK140-2002A patent/SK1402002A3/sk unknown
- 2000-07-26 CZ CZ2002298A patent/CZ2002298A3/cs unknown
- 2000-08-04 AR ARP000104035A patent/AR025042A1/es unknown
-
2002
- 2002-02-06 NO NO20020592A patent/NO20020592L/no not_active Application Discontinuation
- 2002-03-06 ZA ZA200201873A patent/ZA200201873B/xx unknown
-
2003
- 2003-02-20 HK HK03101305.5A patent/HK1049006A1/zh unknown
Also Published As
Publication number | Publication date |
---|---|
AR025042A1 (es) | 2002-11-06 |
BR0013083A (pt) | 2002-04-23 |
HK1049006A1 (zh) | 2003-04-25 |
NO20020592D0 (no) | 2002-02-06 |
HUP0202464A2 (hu) | 2002-12-28 |
CN1368962A (zh) | 2002-09-11 |
HUP0202464A3 (en) | 2003-02-28 |
EP1208088A2 (de) | 2002-05-29 |
WO2001010841A3 (de) | 2001-09-07 |
DE19937394A1 (de) | 2001-02-08 |
AU6828600A (en) | 2001-03-05 |
ZA200201873B (en) | 2003-08-27 |
WO2001010841A2 (de) | 2001-02-15 |
CZ2002298A3 (cs) | 2002-04-17 |
MXPA02001297A (es) | 2004-07-16 |
PL353054A1 (en) | 2003-10-06 |
SK1402002A3 (en) | 2002-06-04 |
JP2003506439A (ja) | 2003-02-18 |
KR20020012631A (ko) | 2002-02-16 |
CA2380981A1 (en) | 2001-02-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC2A | Withdrawal, rejection or dismissal of laid open patent application |