NO20016402L - Trisykliske forbindelser med spiro-kobling - Google Patents

Trisykliske forbindelser med spiro-kobling

Info

Publication number
NO20016402L
NO20016402L NO20016402A NO20016402A NO20016402L NO 20016402 L NO20016402 L NO 20016402L NO 20016402 A NO20016402 A NO 20016402A NO 20016402 A NO20016402 A NO 20016402A NO 20016402 L NO20016402 L NO 20016402L
Authority
NO
Norway
Prior art keywords
tricyclic compounds
useful
relates
spiro
inhibitor
Prior art date
Application number
NO20016402A
Other languages
English (en)
Norwegian (no)
Other versions
NO20016402D0 (no
Inventor
Hidemitsu Nishida
Fumihiko Saitoh
Kousuke Harada
Ikuya Shiromizu
Original Assignee
Mochida Pharm Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mochida Pharm Co Ltd filed Critical Mochida Pharm Co Ltd
Publication of NO20016402D0 publication Critical patent/NO20016402D0/no
Publication of NO20016402L publication Critical patent/NO20016402L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/20—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/95—Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
    • G01N2333/964—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue
    • G01N2333/96425—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals
    • G01N2333/96427—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general
    • G01N2333/9643—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general with EC number
    • G01N2333/96433—Serine endopeptidases (3.4.21)
    • G01N2333/96441—Serine endopeptidases (3.4.21) with definite EC number
    • G01N2333/96444—Factor X (3.4.21.6)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Prostheses (AREA)
  • External Artificial Organs (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
NO20016402A 1999-06-30 2001-12-28 Trisykliske forbindelser med spiro-kobling NO20016402L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP22288399 1999-06-30
PCT/JP2000/004374 WO2001002397A1 (fr) 1999-06-30 2000-06-30 Composes tricycliques presentant une jonction spiro

Publications (2)

Publication Number Publication Date
NO20016402D0 NO20016402D0 (no) 2001-12-28
NO20016402L true NO20016402L (no) 2002-02-27

Family

ID=16789385

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20016402A NO20016402L (no) 1999-06-30 2001-12-28 Trisykliske forbindelser med spiro-kobling

Country Status (21)

Country Link
EP (1) EP1191028B1 (fr)
JP (1) JP4890707B2 (fr)
KR (1) KR20020015061A (fr)
CN (1) CN1371375A (fr)
AT (1) ATE281457T1 (fr)
AU (1) AU774397B2 (fr)
BR (1) BR0012093A (fr)
CA (1) CA2380852C (fr)
CZ (1) CZ20014696A3 (fr)
DE (1) DE60015541T2 (fr)
HK (1) HK1049157A1 (fr)
HU (1) HUP0202188A3 (fr)
IL (1) IL147348A0 (fr)
MX (1) MXPA02000003A (fr)
NO (1) NO20016402L (fr)
NZ (1) NZ516363A (fr)
PL (1) PL352862A1 (fr)
SK (1) SK19292001A3 (fr)
TR (1) TR200103853T2 (fr)
WO (1) WO2001002397A1 (fr)
ZA (1) ZA200110558B (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2416384A1 (fr) * 2000-07-17 2003-01-16 Takeda Chemical Industries, Ltd. Derives de sulfonate, leur production et utilisation
WO2002053568A1 (fr) * 2000-12-28 2002-07-11 Mochida Pharmaceutical Co., Ltd. Inhibiteurs de la biosynthese du cholesterol contenant comme principe actif des composes spiro tricycliques
EP2982668A3 (fr) 2002-12-03 2016-04-13 Pharmacyclics LLC Dérivés de 2-(2-hydroxybiphényl-3-yl)-1h-benzoimidazole-5-carboxamidine en tant qu'inhibiteurs du facteur viia inhibitors pour le traitement de maladies thromboemboliques
TWI396686B (zh) 2004-05-21 2013-05-21 Takeda Pharmaceutical 環狀醯胺衍生物、以及其製品和用法
WO2006006490A1 (fr) * 2004-07-08 2006-01-19 Ono Pharmaceutical Co., Ltd. Composé spirocyclique
CN101175756A (zh) 2005-03-31 2008-05-07 持田制药株式会社 含有与环氮原子结合的酰基的三环螺环化合物
EP2020411A4 (fr) 2006-05-23 2010-08-04 Mochida Pharm Co Ltd Composé spiro tétracyclique
US7739434B2 (en) 2008-01-11 2010-06-15 International Business Machines Corporation Performing a configuration virtual topology change and instruction therefore

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3855147D1 (de) * 1987-07-20 1996-05-02 Duphar Int Res 8,9-Anellierte 1,2,3,4-Tetrahydro-beta-carbolin-Derivate
US5292747A (en) * 1990-08-07 1994-03-08 Hoffman-La Roche Inc. Substituted pyrroles

Also Published As

Publication number Publication date
CN1371375A (zh) 2002-09-25
EP1191028B1 (fr) 2004-11-03
ZA200110558B (en) 2002-09-12
ATE281457T1 (de) 2004-11-15
DE60015541T2 (de) 2005-12-08
PL352862A1 (en) 2003-09-08
CA2380852A1 (fr) 2001-01-11
IL147348A0 (en) 2002-08-14
HUP0202188A2 (en) 2002-10-28
BR0012093A (pt) 2002-07-16
TR200103853T2 (tr) 2002-11-21
EP1191028A1 (fr) 2002-03-27
MXPA02000003A (es) 2003-07-21
AU5572000A (en) 2001-01-22
AU774397B2 (en) 2004-06-24
CZ20014696A3 (cs) 2002-05-15
JP4890707B2 (ja) 2012-03-07
CA2380852C (fr) 2009-10-20
DE60015541D1 (de) 2004-12-09
SK19292001A3 (sk) 2002-06-04
EP1191028A4 (fr) 2002-10-23
WO2001002397A9 (fr) 2001-04-05
NO20016402D0 (no) 2001-12-28
KR20020015061A (ko) 2002-02-27
WO2001002397A1 (fr) 2001-01-11
HK1049157A1 (zh) 2003-05-02
NZ516363A (en) 2004-05-28
HUP0202188A3 (en) 2004-04-28

Similar Documents

Publication Publication Date Title
ATE540928T1 (de) Isochinolinverbindungen und ihre medizinische verwendung
EA200400387A1 (ru) Азабициклические замещённые конденсированные гетероарильные соединения для лечения заболеваний
EA200301216A1 (ru) Замещенные хинуклидинами мультициклические гетероарилы для лечения заболевания
DK1487444T3 (da) Anvendelse af pyridylamider som angiogeneseinhibitorer
NO20053794L (no) N-(1-benzyl-2-oxo-2-(1-piperazinyl) etyl)-1-piperidinkarboksamid-derivater og relaterte forbindelsers bruk som CGRP-antagonister for behandling av hodepine.
DE602006007012D1 (de) Pyridinderivate als dipeptedyl-peptidase-hemmer
NO20062644L (no) DPP-IV inhibitorer
BRPI0116967B8 (pt) derivado de pirazina ou um sal deste, composição farmacêutica, e, derivado de fluoropirazina ou um sal deste
ATE440820T1 (de) 2-phenylpyridinderivat
BR0213660A (pt) Composto, composição farmacêutica e método para tratar pacientes
BRPI0414738A (pt) derivados de ácido acético substituìdos
MY139461A (en) Condensed furan compounds
NO20016402D0 (no) Trisykliske forbindelser med spiro-kobling
WO2007020411A8 (fr) Dérivés amide
DE60122555D1 (de) Spiroverbindungen und diese als wirkstoff enthaltende adhäsionsmolekülinhibitoren
WO2002026732A1 (fr) Derive de benzodiazepine
BRPI0918966A8 (pt) composto inibidor de proteases, composição farmacêutica compreendendo dito compostos e uso terapêutico do mesmo
ECSP056060A (es) Nuevo medicamento
EA200401432A1 (ru) Сложноэфирные производные декагидроизохинолин-3-карбоновой кислоты в качестве анальгетиков
EA200301062A1 (ru) Фармацевтические комбинации на основе производных пиридоиндолона и противораковых агентов
TH80960B (th) ซัลฟานิลแทนที่ฟีนิลเมทธาโนนซ์
TH80960A (th) ซัลฟานิลแทนที่ฟีนิลเมทธาโนนซ์
TH77099A (th) สารประกอบต้านไวรัสชนิดเฮเทอโรไซคลิก
TH64361A (th) อนุพันธ์ เบนโซฟูแรน

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application