NO20013338D0 - BIS amino acid sulfonamides containing N-terminally a substituted benzyl group as HIV protease inhibitors - Google Patents

BIS amino acid sulfonamides containing N-terminally a substituted benzyl group as HIV protease inhibitors

Info

Publication number
NO20013338D0
NO20013338D0 NO20013338A NO20013338A NO20013338D0 NO 20013338 D0 NO20013338 D0 NO 20013338D0 NO 20013338 A NO20013338 A NO 20013338A NO 20013338 A NO20013338 A NO 20013338A NO 20013338 D0 NO20013338 D0 NO 20013338D0
Authority
NO
Norway
Prior art keywords
terminally
amino acid
benzyl group
protease inhibitors
substituted benzyl
Prior art date
Application number
NO20013338A
Other languages
Norwegian (no)
Other versions
NO20013338L (en
Inventor
Robert Frank Kaltenbach
George L Trainor
Original Assignee
Du Pont Pharm Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Du Pont Pharm Co filed Critical Du Pont Pharm Co
Publication of NO20013338D0 publication Critical patent/NO20013338D0/en
Publication of NO20013338L publication Critical patent/NO20013338L/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06191—Dipeptides containing heteroatoms different from O, S, or N
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Virology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NO20013338A 1999-01-13 2001-07-05 Bis-amino acid sulfonamides containing N-terminally a substituted benzyl group as HIV protease inhibitors NO20013338L (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11574699P 1999-01-13 1999-01-13
PCT/US2000/000820 WO2000042060A1 (en) 1999-01-13 2000-01-13 Bis-amino acid sulfonamides containing n-terminally a substituted benzyl group as hiv protease inhibitors

Publications (2)

Publication Number Publication Date
NO20013338D0 true NO20013338D0 (en) 2001-07-05
NO20013338L NO20013338L (en) 2001-09-13

Family

ID=22363180

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20013338A NO20013338L (en) 1999-01-13 2001-07-05 Bis-amino acid sulfonamides containing N-terminally a substituted benzyl group as HIV protease inhibitors

Country Status (15)

Country Link
EP (1) EP1140983A1 (en)
JP (1) JP2002536298A (en)
KR (1) KR20010101478A (en)
CN (1) CN1336934A (en)
AU (1) AU2725700A (en)
BR (1) BR0007854A (en)
CA (1) CA2353088A1 (en)
CZ (1) CZ20012435A3 (en)
HU (1) HUP0105235A3 (en)
IL (1) IL143763A0 (en)
NO (1) NO20013338L (en)
PL (1) PL349774A1 (en)
SK (1) SK9522001A3 (en)
TR (1) TR200102033T2 (en)
WO (1) WO2000042060A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1188766A1 (en) * 1995-03-10 2002-03-20 G.D. Searle & Co. Bis-amino acid hydroxyethylamino sulfonamide retroviral protease inhibitors
US6861539B1 (en) 1995-03-10 2005-03-01 G. D. Searle & Co. Bis-amino acid hydroxyethylamino sulfonamide retroviral protease inhibitors
US7339078B2 (en) 1995-03-10 2008-03-04 G.D. Searle Llc Bis-amino acid hydroxyethylamino sulfonamide retroviral protease inhibitors
US20020022742A1 (en) * 2000-07-19 2002-02-21 Harris Gregory D. Salt forms of an HIV protease inhibitor
US20020022659A1 (en) * 2000-07-19 2002-02-21 Harris Gregory D. Crystalline and salt forms of an HIV protease inhibitor
US6617310B2 (en) 2000-07-19 2003-09-09 Bristol-Myers Squibb Pharma Company Phosphate esters of bis-amino acid sulfonamides containing substituted benzyl amines

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0656887T3 (en) * 1992-08-25 1999-07-05 Searle & Co Hydroxyethylaminosulfonamides for use as inhibitors of retroviral proteases
AU7669794A (en) * 1993-08-24 1995-03-21 G.D. Searle & Co. Hydroxyethylamino sulphonamides useful as retroviral protease inhibitors
US6150556A (en) * 1995-03-10 2000-11-21 G. D. Dearle & Co. Bis-amino acid hydroxyethylamino sulfonamide retroviral protease inhibitors

Also Published As

Publication number Publication date
TR200102033T2 (en) 2001-12-21
NO20013338L (en) 2001-09-13
WO2000042060A1 (en) 2000-07-20
SK9522001A3 (en) 2002-03-05
HUP0105235A3 (en) 2002-08-28
CN1336934A (en) 2002-02-20
PL349774A1 (en) 2002-09-09
AU2725700A (en) 2000-08-01
KR20010101478A (en) 2001-11-14
JP2002536298A (en) 2002-10-29
BR0007854A (en) 2002-01-15
CZ20012435A3 (en) 2002-02-13
HUP0105235A2 (en) 2002-04-29
EP1140983A1 (en) 2001-10-10
CA2353088A1 (en) 2000-07-20
IL143763A0 (en) 2002-04-21

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Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application