NO20011251L - Delivery to lung of active agent from dry powder - Google Patents

Delivery to lung of active agent from dry powder

Info

Publication number
NO20011251L
NO20011251L NO20011251A NO20011251A NO20011251L NO 20011251 L NO20011251 L NO 20011251L NO 20011251 A NO20011251 A NO 20011251A NO 20011251 A NO20011251 A NO 20011251A NO 20011251 L NO20011251 L NO 20011251L
Authority
NO
Norway
Prior art keywords
active agent
lung
dry powder
delivery
delivering
Prior art date
Application number
NO20011251A
Other languages
Norwegian (no)
Other versions
NO20011251D0 (en
Inventor
Andrew Clark
Mei-Chang Kuo
Cecily Lalor
Barry John Aldous
Original Assignee
Inhale Therapeutic Syst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inhale Therapeutic Syst filed Critical Inhale Therapeutic Syst
Publication of NO20011251D0 publication Critical patent/NO20011251D0/en
Publication of NO20011251L publication Critical patent/NO20011251L/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Otolaryngology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)

Abstract

Det er beskrevet partikkelformige preparater og fremgangsmåter for avlevering av et aktivt middel til lungen av en human pasient. Preparatet av det aktive middelet er i tørr pulverform og viser (i) lav fuktighetssorpsjon, og (ii) en motstand mot hygroskopisk vekst, spesielt under simulerte lungebetingelser.Particulate compositions and methods for delivering an active agent to the lung of a human patient are described. The preparation of the active agent is in dry powder form and shows (i) low moisture sorption, and (ii) a resistance to hygroscopic growth, especially under simulated lung conditions.

NO20011251A 1998-09-14 2001-03-13 Delivery to lung of active agent from dry powder NO20011251L (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10016398P 1998-09-14 1998-09-14
PCT/US1999/021109 WO2000015262A1 (en) 1998-09-14 1999-09-13 Dry powder active agent pulmonary delivery

Publications (2)

Publication Number Publication Date
NO20011251D0 NO20011251D0 (en) 2001-03-13
NO20011251L true NO20011251L (en) 2001-04-17

Family

ID=22278404

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20011251A NO20011251L (en) 1998-09-14 2001-03-13 Delivery to lung of active agent from dry powder

Country Status (44)

Country Link
EP (1) EP1117442A1 (en)
JP (1) JP2002524535A (en)
KR (1) KR20010075063A (en)
CN (1) CN1317977A (en)
AP (1) AP1374A (en)
AR (1) AR022090A1 (en)
AU (1) AU753014B2 (en)
BG (1) BG105430A (en)
BR (1) BR9913722A (en)
CA (1) CA2343920A1 (en)
CO (1) CO5130023A1 (en)
CZ (1) CZ2001829A3 (en)
DZ (1) DZ2892A1 (en)
EA (1) EA003476B1 (en)
EE (1) EE200100151A (en)
GE (1) GEP20043257B (en)
GT (1) GT199900156A (en)
HK (1) HK1042231A1 (en)
HN (1) HN1999000159A (en)
HR (1) HRP20010189A2 (en)
HU (1) HUP0103837A3 (en)
ID (1) ID28845A (en)
IL (2) IL141562A0 (en)
IS (1) IS5878A (en)
LT (1) LT4897B (en)
LV (1) LV12658B (en)
MA (1) MA25590A1 (en)
MY (1) MY129282A (en)
NO (1) NO20011251L (en)
NZ (1) NZ510168A (en)
OA (1) OA11781A (en)
PA (1) PA8481901A1 (en)
PE (1) PE20001061A1 (en)
PL (1) PL195574B1 (en)
SA (1) SA99200718B1 (en)
SK (1) SK3442001A3 (en)
TN (1) TNSN99173A1 (en)
TR (1) TR200101182T2 (en)
TW (1) TWI226248B (en)
UA (1) UA76085C2 (en)
UY (1) UY25711A1 (en)
WO (1) WO2000015262A1 (en)
YU (1) YU24201A (en)
ZA (1) ZA200101995B (en)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1185248B1 (en) 1999-06-09 2012-05-02 Robert E. Sievers Supercritical fluid-assisted nebulization and bubble drying
US6475468B2 (en) * 2001-02-15 2002-11-05 Aeropharm Technology Incorporated Modulated release particles for aerosol delivery
US6737042B2 (en) * 2001-05-24 2004-05-18 Alexza Molecular Delivery Corporation Delivery of drug esters through an inhalation route
EG24184A (en) 2001-06-15 2008-10-08 Otsuka Pharma Co Ltd Dry powder inhalation system for transpulmonary
US7351844B2 (en) 2002-02-25 2008-04-01 Diffusion Pharmaceuticals Llc Bipolar trans carotenoid salts and their uses
US7759506B2 (en) 2002-02-25 2010-07-20 Diffusion Pharmaceuticals Llc Bipolar trans carotenoid salts and their uses
EP1539246A4 (en) * 2002-07-03 2007-05-16 Brigham & Womens Hospital Central airway administration for systemic delivery of therapeutics
AU2003298010A1 (en) * 2002-12-19 2004-07-29 Pharmacia Corporation Non-hygroscopic formulation comprising a hydroscopic drug
DE10338403A1 (en) * 2003-08-18 2005-03-17 Boehringer Ingelheim Pharma Gmbh & Co. Kg Powder formulation containing the CGRP antagonist 1- [N 2 - [3,5-dibromo-N - [[4- (3,4-dihydro-2 (1 H) -oxoquinazolin-3-yl] -1-piperidinyl] carbonyl] -D-tyrosyl] -L-lysyl] -4- (4-pyrindinyl) piperazine, process for its preparation and its use as inhalant
GB0327723D0 (en) * 2003-09-15 2003-12-31 Vectura Ltd Pharmaceutical compositions
US20070020299A1 (en) 2003-12-31 2007-01-25 Pipkin James D Inhalant formulation containing sulfoalkyl ether cyclodextrin and corticosteroid
AU2005237523A1 (en) * 2004-04-23 2005-11-10 Cydex Pharmaceuticals, Inc. DPI formulation containing sulfoalkyl ether cyclodextrin
UA95903C2 (en) 2005-02-24 2011-09-26 Дифьюжен Фармасьютикалз Ллк Trans carotenoids, their synthesis, formulation and uses
JPWO2006095788A1 (en) * 2005-03-09 2008-08-14 小野薬品工業株式会社 Particles and formulations containing the particles
PL2335707T3 (en) 2005-10-26 2015-10-30 Cydex Pharmaceuticals Inc Sulfoalkyl ether cyclodextrin compositions and methods of preparation thereof
US7629331B2 (en) 2005-10-26 2009-12-08 Cydex Pharmaceuticals, Inc. Sulfoalkyl ether cyclodextrin compositions and methods of preparation thereof
WO2008021451A2 (en) * 2006-08-14 2008-02-21 Aktiv-Dry Llc Human-powered dry powder inhaler and dry powder inhaler compositions
EP2095812A4 (en) * 2006-10-25 2011-07-13 Dainippon Sumitomo Pharma Co Granular preparation prevented from caking
EP1925295A1 (en) * 2006-11-22 2008-05-28 Boehringer Ingelheim Pharma GmbH & Co. KG Stable powder formulation containing a new antichinolinergic agent
JP2010524855A (en) 2007-04-13 2010-07-22 ディフュージョン・ファーマシューティカルズ・エルエルシー Use of bipolar trans carotenoids as and in the pretreatment of peripheral vascular disease
EA201070544A1 (en) 2007-10-31 2010-12-30 Диффьюжн Фармасьютикалз Ллс NEW CLASS OF THERAPEUTIC SUBSTANCES STRENGTHENING THE DIFFUSION OF LOW MOLECULAR COMPOUNDS
EP2432502B1 (en) * 2009-05-20 2018-01-03 Aeras Stable, spray dried, immunogenic, viral compositions
AU2010263245A1 (en) 2009-06-22 2012-01-19 Diffusion Pharmaceuticals Llc Diffusion enhancing compounds and their use alone or with thrombolytics
AU2011262361A1 (en) 2010-06-02 2013-01-10 Diffusion Pharmaceuticals Llc Oral formulations of bipolar trans carotenoids
EP2846767B1 (en) 2012-05-03 2022-01-26 Janssen Sciences Ireland Unlimited Company Polyinosinic-polycytidylic acid (poly (i:c)) formulations for the treatment of upper respiratory tract infections
WO2014074797A1 (en) * 2012-11-09 2014-05-15 Civitas Therapeutics, Inc. Ultra low density pulmonary powders
US20180043585A9 (en) * 2013-09-20 2018-02-15 Virginia Commonwealth University Delivery of particles using hygroscopic excipients
BR112017008923A2 (en) 2014-10-31 2017-12-26 Glaxosmithkline Ip Dev Ltd ? powder formulation?
KR102489034B1 (en) 2016-03-24 2023-01-13 디퓨젼 파마슈티컬즈 엘엘씨 Use of Bipolar Trans Carotenoids with Chemotherapy and Radiation Therapy to Treat Cancer

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3155573A (en) * 1958-05-06 1964-11-03 Benger Lab Ltd Inhalant composition and method of making same
ATE222754T1 (en) * 1992-06-12 2002-09-15 Teijin Ltd ULTRA FINE POWDER FOR INHALATION AND ITS PRODUCTION
US6524557B1 (en) * 1994-12-22 2003-02-25 Astrazeneca Ab Aerosol formulations of peptides and proteins
US5874064A (en) 1996-05-24 1999-02-23 Massachusetts Institute Of Technology Aerodynamically light particles for pulmonary drug delivery
ATE287257T1 (en) * 1997-01-16 2005-02-15 Massachusetts Inst Technology PREPARATION OF PARTICLE-CONTAINING MEDICINAL PRODUCTS FOR INHALATION
US6086376A (en) * 1998-01-30 2000-07-11 Rtp Pharma Inc. Dry aerosol suspension of phospholipid-stabilized drug microparticles in a hydrofluoroalkane propellant

Also Published As

Publication number Publication date
MA25590A1 (en) 2002-12-31
BG105430A (en) 2001-12-29
HRP20010189A2 (en) 2005-04-30
HUP0103837A2 (en) 2002-05-29
PE20001061A1 (en) 2000-10-08
AP2001002093A0 (en) 2001-03-31
SA99200718B1 (en) 2006-11-04
JP2002524535A (en) 2002-08-06
AU753014B2 (en) 2002-10-03
ZA200101995B (en) 2002-03-11
HK1042231A1 (en) 2002-08-09
OA11781A (en) 2005-07-26
AP1374A (en) 2005-02-28
LT2001021A (en) 2001-11-26
LT4897B (en) 2002-02-25
ID28845A (en) 2001-07-05
NZ510168A (en) 2003-09-26
UY25711A1 (en) 1999-11-17
TR200101182T2 (en) 2001-09-21
WO2000015262A1 (en) 2000-03-23
IL141562A0 (en) 2002-03-10
PA8481901A1 (en) 2002-04-25
UA76085C2 (en) 2006-07-17
YU24201A (en) 2003-08-29
EA003476B1 (en) 2003-06-26
GEP20043257B (en) 2004-06-25
CO5130023A1 (en) 2002-02-27
HN1999000159A (en) 1999-11-11
IS5878A (en) 2001-03-05
CA2343920A1 (en) 2000-03-23
TNSN99173A1 (en) 2005-11-10
PL346768A1 (en) 2002-02-25
LV12658A (en) 2001-05-20
AR022090A1 (en) 2002-09-04
EP1117442A1 (en) 2001-07-25
CN1317977A (en) 2001-10-17
SK3442001A3 (en) 2001-11-06
IL141562A (en) 2007-07-24
KR20010075063A (en) 2001-08-09
DZ2892A1 (en) 2003-12-15
EA200100300A1 (en) 2001-10-22
GT199900156A (en) 2001-03-07
HUP0103837A3 (en) 2002-11-28
LV12658B (en) 2001-09-20
NO20011251D0 (en) 2001-03-13
CZ2001829A3 (en) 2001-09-12
TWI226248B (en) 2005-01-11
AU6039799A (en) 2000-04-03
MY129282A (en) 2007-03-30
EE200100151A (en) 2002-06-17
BR9913722A (en) 2001-05-29
PL195574B1 (en) 2007-10-31

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Legal Events

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FC2A Withdrawal, rejection or dismissal of laid open patent application