NO20006352L - Anvendelse av diazepiner til fremstilling av medisiner for behandling av patologiske tilstander eller sykdommer som involverer en av veksthormon-frigjöringsinhiberingsfaktor- reseptorene - Google Patents

Anvendelse av diazepiner til fremstilling av medisiner for behandling av patologiske tilstander eller sykdommer som involverer en av veksthormon-frigjöringsinhiberingsfaktor- reseptorene Download PDF

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Publication number
NO20006352L
NO20006352L NO20006352A NO20006352A NO20006352L NO 20006352 L NO20006352 L NO 20006352L NO 20006352 A NO20006352 A NO 20006352A NO 20006352 A NO20006352 A NO 20006352A NO 20006352 L NO20006352 L NO 20006352L
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Norway
Prior art keywords
diazepines
treatment
medicaments
manufacture
pathological conditions
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NO20006352A
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English (en)
Norwegian (no)
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NO20006352D0 (no
Inventor
Dennis C H Bigg
Anne-Marie Liberatore
Jacques Pommier
John E Taylor
Original Assignee
Sod Conseils Rech Applic
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Application filed by Sod Conseils Rech Applic filed Critical Sod Conseils Rech Applic
Publication of NO20006352L publication Critical patent/NO20006352L/no
Publication of NO20006352D0 publication Critical patent/NO20006352D0/no

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/22Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Neurosurgery (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Dermatology (AREA)
  • Reproductive Health (AREA)
  • Emergency Medicine (AREA)
  • Oncology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
NO20006352A 1998-06-15 2000-12-13 Anvendelse av diazepiner til fremstilling av medisiner for behandling av patologiske tilstander eller sykdommer som involverer en av veksthormon-frigjöringsinhiberingsfaktor- reseptorene NO20006352D0 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9807509A FR2779652B1 (fr) 1998-06-15 1998-06-15 Utilisation de diazepines pour la preparation de medicaments destines a traiter les etats pathologiques ou les maladies dans lesquels un des recepteurs de la somatostatine est implique
PCT/FR1999/001422 WO1999065917A1 (fr) 1998-06-15 1999-06-15 Utilisation de diazepines pour la preparation de medicaments destines a traiter les etats pathologiques ou les maladies dans lesquels un des recepteurs de la somatostatine est implique

Publications (2)

Publication Number Publication Date
NO20006352L true NO20006352L (no) 2000-12-13
NO20006352D0 NO20006352D0 (no) 2000-12-13

Family

ID=9527389

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20006352A NO20006352D0 (no) 1998-06-15 2000-12-13 Anvendelse av diazepiner til fremstilling av medisiner for behandling av patologiske tilstander eller sykdommer som involverer en av veksthormon-frigjöringsinhiberingsfaktor- reseptorene

Country Status (19)

Country Link
US (1) US7015213B1 (es)
EP (1) EP1087978A1 (es)
JP (1) JP2002518400A (es)
KR (1) KR20010052836A (es)
CN (1) CN100348600C (es)
AR (1) AR019669A1 (es)
AU (1) AU758206B2 (es)
CA (1) CA2335724A1 (es)
FR (1) FR2779652B1 (es)
HK (1) HK1039780A1 (es)
HU (1) HUP0102300A3 (es)
IL (1) IL139954A0 (es)
MY (1) MY118652A (es)
NO (1) NO20006352D0 (es)
NZ (1) NZ509313A (es)
PL (1) PL344831A1 (es)
RU (1) RU2229299C2 (es)
TW (1) TW513434B (es)
WO (1) WO1999065917A1 (es)

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US6987105B2 (en) * 2000-04-28 2006-01-17 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Synthesis and use of thienotriazolodiazepines
WO2002057241A1 (en) * 2000-12-22 2002-07-25 Bayer Pharmaceuticals Corporation 8-(AMINOALKOXYMINO)-8H-DIBENZO[a,e]TRIAZOLO[4,5-c]CYCLOHEPTENES AS GROWTH HORMONE SECRETAGOGUES
WO2009084693A1 (ja) 2007-12-28 2009-07-09 Mitsubishi Tanabe Pharma Corporation 抗癌剤
BR112012029057A2 (pt) 2010-05-14 2020-10-13 Dana-Farber Cancer Institute, Inc. composições e métodos de tratamento de leucemia
CA2799381A1 (en) 2010-05-14 2011-11-17 Dana-Farber Cancer Institute, Inc. Male contraceptive compositions and methods of use
EP2902030B1 (en) 2010-05-14 2016-09-14 Dana-Farber Cancer Institute, Inc. Thienotriazolodiazepine compounds for treating neoplasia
AR084070A1 (es) 2010-12-02 2013-04-17 Constellation Pharmaceuticals Inc Inhibidores del bromodominio y usos de los mismos
US9249161B2 (en) 2010-12-02 2016-02-02 Constellation Pharmaceuticals, Inc. Bromodomain inhibitors and uses thereof
US9422292B2 (en) 2011-05-04 2016-08-23 Constellation Pharmaceuticals, Inc. Bromodomain inhibitors and uses thereof
WO2012174487A2 (en) 2011-06-17 2012-12-20 Constellation Pharmaceuticals, Inc. Bromodomain inhibitors and uses thereof
TWI602820B (zh) 2012-06-06 2017-10-21 星宿藥物公司 溴域抑制劑及其用途
EP2864336B1 (en) 2012-06-06 2016-11-23 Constellation Pharmaceuticals, Inc. Benzo[b]isoxazoloazepine bromodomain inhibitors and uses thereof
BR112016001457A2 (pt) 2013-07-25 2017-08-29 Dana Farber Cancer Inst Inc Inibidores de fatores de transcrição e usos dos mesmos
US11446309B2 (en) 2013-11-08 2022-09-20 Dana-Farber Cancer Institute, Inc. Combination therapy for cancer using bromodomain and extra-terminal (BET) protein inhibitors
RU2016134947A (ru) 2014-01-31 2018-03-01 Дана-Фарбер Кансер Институт, Инк. Производные диаминопиримидин бензолсульфона и их применение
JP2017504651A (ja) 2014-01-31 2017-02-09 ダナ−ファーバー キャンサー インスティテュート, インコーポレイテッド ジアゼパン誘導体の使用
WO2015131113A1 (en) * 2014-02-28 2015-09-03 Tensha Therapeutics, Inc. Treatment of conditions associated with hyperinsulinaemia
EP3157928B1 (en) 2014-06-20 2019-02-13 Constellation Pharmaceuticals, Inc. Crystalline forms of 2-((4s)-6-(4-chlorophenyl)-1-methyl-4h-benzo[c]isoxazolo[4,5-e]azepin-4-yl)acetamide
JP2017525759A (ja) 2014-08-08 2017-09-07 ダナ−ファーバー キャンサー インスティテュート, インコーポレイテッド ジヒドロプテリジノン誘導体およびその使用
JP2017526741A (ja) 2014-08-08 2017-09-14 ダナ−ファーバー キャンサー インスティテュート, インコーポレイテッド ジアゼパン誘導体およびその使用
WO2016069578A1 (en) 2014-10-27 2016-05-06 Tensha Therapeutics, Inc. Bromodomain inhibitors
WO2016201370A1 (en) 2015-06-12 2016-12-15 Dana-Farber Cancer Institute, Inc. Combination therapy of transcription inhibitors and kinase inhibitors
BR112018004617A2 (pt) 2015-09-11 2018-09-25 Dana Farber Cancer Inst Inc acetamida tienotriazoldiazepinas e usos das mesmas
RU2750164C2 (ru) * 2015-09-11 2021-06-22 Дана-Фарбер Кэнсер Инститьют, Инк. Цианотиенотриазолодиазепины и пути их применения
CR20180336A (es) 2015-11-25 2018-08-06 Dana Farber Cancer Inst Inc Inhibidores de bromodominio bivalentes y usos de los mismos
JOP20200030A1 (ar) * 2017-09-07 2020-02-12 Eisai R&D Man Co Ltd مركب خماسي الحلقة
AU2020233452A1 (en) 2019-03-05 2021-09-02 Eisai R&D Management Co., Ltd. Salt of pentacyclic compound and crystals thereof
EA202191966A1 (ru) 2019-03-05 2021-12-08 Эйсай Ар Энд Ди Менеджмент Ко., Лтд. Пентациклическое гетероциклическое соединение
CN111533745A (zh) * 2020-05-20 2020-08-14 成都药明康德新药开发有限公司 叔丁基-3-(氨基甲基)二氢-5h-三唑并二氮杂卓-8(9h)-甲酸基酯制法
AU2021379248A1 (en) 2020-11-16 2023-06-22 Boehringer Ingelheim International Gmbh Cyclopentathiophene carboxamide derivatives as platelet activating factor receptor antagonists
US11992494B2 (en) 2021-12-22 2024-05-28 Boehringer Ingelheim International Gmbh Cyclopentathiophene carboxamide derivatives as platelet activating factor receptor antagonists

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FI95708C (fi) * 1988-10-31 1996-03-11 Eisai Co Ltd Analogiamenetelmä 1,4-diatsepiinijohdannaisen ja sen farmaseuttisesti sopivan suolan valmistamiseksi
GB8907256D0 (en) * 1989-03-31 1989-05-17 Rech Et D Applic Scient Scras New derivatives of hetrazepine as anti-asthmatic anti-allergic and gastro-intestinal protectors
OA09202A (fr) * 1990-04-02 1992-06-30 Sod Conseils Rech Applic Procédé de préparation des nouveaux dérivés de la thiéno-triazolo-diazépine.
DE4107521A1 (de) * 1991-03-08 1992-09-10 Boehringer Ingelheim Kg Neue acylaminosubstituierte hetrazepine
EP0638560A4 (en) * 1991-10-11 1995-03-29 Yoshitomi Pharmaceutical MEDICINE FOR OSTEOPOROSIS AND DIAZEPINE COMPOUND *.
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Also Published As

Publication number Publication date
CN1309657A (zh) 2001-08-22
CA2335724A1 (fr) 1999-12-23
MY118652A (en) 2004-12-31
EP1087978A1 (fr) 2001-04-04
US7015213B1 (en) 2006-03-21
IL139954A0 (en) 2002-02-10
HUP0102300A3 (en) 2002-10-28
NZ509313A (en) 2002-11-26
HUP0102300A2 (hu) 2001-11-28
AR019669A1 (es) 2002-03-13
FR2779652A1 (fr) 1999-12-17
AU758206B2 (en) 2003-03-20
RU2229299C2 (ru) 2004-05-27
CN100348600C (zh) 2007-11-14
KR20010052836A (ko) 2001-06-25
TW513434B (en) 2002-12-11
JP2002518400A (ja) 2002-06-25
HK1039780A1 (zh) 2002-05-10
AU4149599A (en) 2000-01-05
NO20006352D0 (no) 2000-12-13
FR2779652B1 (fr) 2001-06-08
PL344831A1 (en) 2001-11-19
WO1999065917A1 (fr) 1999-12-23

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