NO20005755D0 - Kombinasjonsterapi omfattende ribavirin og interferon <alfa> i antivirusbehandling av naive pasienter med kronisk hepatitt C- infeksjon - Google Patents

Kombinasjonsterapi omfattende ribavirin og interferon <alfa> i antivirusbehandling av naive pasienter med kronisk hepatitt C- infeksjon

Info

Publication number
NO20005755D0
NO20005755D0 NO20005755A NO20005755A NO20005755D0 NO 20005755 D0 NO20005755 D0 NO 20005755D0 NO 20005755 A NO20005755 A NO 20005755A NO 20005755 A NO20005755 A NO 20005755A NO 20005755 D0 NO20005755 D0 NO 20005755D0
Authority
NO
Norway
Prior art keywords
ribavirin
alfa
interferon
infection
combination therapy
Prior art date
Application number
NO20005755A
Other languages
English (en)
Other versions
NO330715B1 (no
NO20005755L (no
Inventor
Janice K Albrecht
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22151354&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20005755(D0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Schering Corp filed Critical Schering Corp
Publication of NO20005755D0 publication Critical patent/NO20005755D0/no
Publication of NO20005755L publication Critical patent/NO20005755L/no
Publication of NO330715B1 publication Critical patent/NO330715B1/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A61K38/212—IFN-alpha
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
NO20005755A 1998-05-15 2000-11-14 Anvendelse av ribavirin og interferon-alfa i kombinasjon for fremstilling av et farmasoytisk preparat for behandling av kronisk hepatitt-C-infeksjon hos pasienter som har HCV-genotype-1 med en virusmengde over 2 millioner kopier per ml serum. NO330715B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US7956698A 1998-05-15 1998-05-15
PCT/US1999/007037 WO1999059621A1 (en) 1998-05-15 1999-05-13 Combination therapy comprising ribavirin and interferon alpha in antiviral treatment naive patients having g chronic hepatitis c infection

Publications (3)

Publication Number Publication Date
NO20005755D0 true NO20005755D0 (no) 2000-11-14
NO20005755L NO20005755L (no) 2001-01-12
NO330715B1 NO330715B1 (no) 2011-06-20

Family

ID=22151354

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20005755A NO330715B1 (no) 1998-05-15 2000-11-14 Anvendelse av ribavirin og interferon-alfa i kombinasjon for fremstilling av et farmasoytisk preparat for behandling av kronisk hepatitt-C-infeksjon hos pasienter som har HCV-genotype-1 med en virusmengde over 2 millioner kopier per ml serum.

Country Status (23)

Country Link
EP (3) EP0956861B1 (no)
JP (2) JP5281726B2 (no)
KR (1) KR100694345B1 (no)
CN (1) CN1230198C (no)
AR (1) AR019551A1 (no)
AT (1) ATE216591T1 (no)
AU (2) AU766597B2 (no)
BR (1) BR9910505A (no)
CA (1) CA2331823A1 (no)
CZ (1) CZ300540B6 (no)
DE (1) DE69901321T2 (no)
DK (1) DK0956861T3 (no)
ES (1) ES2172288T3 (no)
HK (1) HK1021131A1 (no)
HU (1) HU230432B1 (no)
IL (3) IL139220A0 (no)
MY (1) MY129244A (no)
NO (1) NO330715B1 (no)
NZ (1) NZ507621A (no)
PT (1) PT956861E (no)
SK (1) SK288038B6 (no)
TW (1) TWI277424B (no)
WO (1) WO1999059621A1 (no)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2157000A (en) * 1998-12-18 2000-07-12 Schering Corporation Ribavirin-pegylated interferon alfa induction hcv combination therapy
EP1244356A4 (en) * 1999-12-23 2003-03-19 Icn Pharmaceuticals COMPOSITIONS AND METHODS RELATING TO NUCLEOSIDES-L, NUCLEOTIDES-L AND THEIR ANALOGS
JP4536194B2 (ja) * 2000-02-17 2010-09-01 大日本住友製薬株式会社 安定な注射用製剤
AU2001266557A1 (en) 2000-04-12 2001-10-23 Human Genome Sciences, Inc. Albumin fusion proteins
MY164523A (en) 2000-05-23 2017-12-29 Univ Degli Studi Cagliari Methods and compositions for treating hepatitis c virus
AU2001272923A1 (en) 2000-05-26 2001-12-11 Idenix (Cayman) Limited Methods and compositions for treating flaviviruses and pestiviruses
AU2002213343A1 (en) * 2000-10-18 2002-04-29 Schering Corporation Ribavirin-pegylated interferon alfa HCV combination therapy
US20030143197A1 (en) * 2001-11-09 2003-07-31 Moran S. Mark Method for treating diseases with omega interferon
WO2003060071A2 (en) 2001-12-21 2003-07-24 Human Genome Sciences, Inc. Albumin fusion proteins
US7662798B2 (en) 2002-06-28 2010-02-16 Idenix Pharmaceuticals, Inc. 2′ and 3′-nucleoside prodrugs for treating Flaviviridae infections
US7608600B2 (en) 2002-06-28 2009-10-27 Idenix Pharmaceuticals, Inc. Modified 2′ and 3′-nucleoside prodrugs for treating Flaviviridae infections
CN103319554A (zh) 2002-06-28 2013-09-25 埃迪尼克斯医药公司 用于治疗黄病毒感染的修饰的2’和3’-核苷前药
JP2006519753A (ja) 2002-11-15 2006-08-31 イデニクス（ケイマン）リミテツド ２’−分枝ヌクレオシドおよびフラビウイルス科ウイルス突然変異
US20050049204A1 (en) * 2003-03-28 2005-03-03 Otto Michael J. Compounds for the treatment of flaviviridae infections
CA2520148A1 (en) * 2003-04-01 2004-12-23 Intermune, Inc. Compositions and methods for treating coronavirus infection and sars
US20070026014A1 (en) * 2003-04-17 2007-02-01 Ares Trading S.A. Interferon beta in severe acute respiratory syndrome (sars)
SI2604620T1 (sl) 2003-05-30 2016-10-28 Gilead Pharmasset LLC c/o Gilead Sciences, Inc. Modificirani fluorirani nukleozidni analogi
US7482149B2 (en) * 2003-06-09 2009-01-27 Genome Institute Of Singapore Inhibition of SARS coronavirus infection with clinically approved antiviral drugs
CA2535451A1 (en) * 2003-08-13 2005-02-24 Howard J. Smith & Associates Pty Ltd. Method of treating viral infections
AR045870A1 (es) * 2003-10-11 2005-11-16 Vertex Pharma Terapia de combinacion para la infeccion de virus de hepatitis c
PT3109244T (pt) 2004-09-14 2019-06-04 Gilead Pharmasset Llc ¿preparação de ribofuranosil pirimidinas e purinas 2¿-fluoro-2¿-alquil substituídas ou outras opcionalmente substituídas e os seus derivados
TW201424733A (zh) * 2004-10-29 2014-07-01 Vertex Pharma 劑量型式
AP2907A (en) 2006-01-09 2014-05-31 Romark Lab Lc Viral hepatitis treatment
US7964580B2 (en) 2007-03-30 2011-06-21 Pharmasset, Inc. Nucleoside phosphoramidate prodrugs
EP2175865A4 (en) 2007-07-25 2012-01-11 Biolex Therapeutics Inc INTERFERON DRUG PRODUCTS WITH CONTROLLED RELEASE AND TREATMENT OF HCV INFECTIONS THEREWITH
TW200946541A (en) 2008-03-27 2009-11-16 Idenix Pharmaceuticals Inc Solid forms of an anti-HIV phosphoindole compound
WO2010075517A2 (en) 2008-12-23 2010-07-01 Pharmasset, Inc. Nucleoside analogs
EA019295B1 (ru) 2008-12-23 2014-02-28 Джилид Фармассет, Ллс. Соединения пуриновых нуклеозидов и способ их получения
MX2011006891A (es) 2008-12-23 2011-10-06 Pharmasset Inc Fosforamidatos de nucleosidos.
US8716012B2 (en) 2009-05-08 2014-05-06 Sciclone Pharmaceuticals, Inc. Alpha thymosin peptides as vaccine enhancers
US8618076B2 (en) 2009-05-20 2013-12-31 Gilead Pharmasset Llc Nucleoside phosphoramidates
TWI583692B (zh) 2009-05-20 2017-05-21 基利法瑪席特有限責任公司 核苷磷醯胺
HUE034239T2 (en) 2010-03-31 2018-02-28 Gilead Pharmasset Llc Method for Crystallization of (S) -isopropyl 2 - (((S) (perfluorophenoxy) (phenoxy) phosphoryl) amino) propanoate \ t
WO2012045704A1 (en) * 2010-10-05 2012-04-12 Novartis Ag New treatments of hepatitis c virus infection
EP2646453A1 (en) 2010-11-30 2013-10-09 Gilead Pharmasset LLC Compounds
KR20190060879A (ko) * 2011-03-02 2019-06-03 제롬 쉔타그 단독으로 또는 c형 간염 바이러스 감염과 결합되는 간 지방증의 치료를 위한 조성물, 방법 및 진단
DE202012013074U1 (de) 2011-09-16 2014-10-29 Gilead Pharmasset Lcc Zusammensetzungen zur Behandlung von HCV
US8889159B2 (en) 2011-11-29 2014-11-18 Gilead Pharmasset Llc Compositions and methods for treating hepatitis C virus
SG10201706949VA (en) 2013-01-31 2017-09-28 Gilead Pharmasset Llc Combination formulation of two antiviral compounds
EP4005560A1 (en) 2013-08-27 2022-06-01 Gilead Pharmasset LLC Combination formulation of two antiviral compounds

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4211771A (en) 1971-06-01 1980-07-08 Robins Ronald K Treatment of human viral diseases with 1-B-D-ribofuranosyl-1,2,4-triazole-3-carboxamide
US4530901A (en) 1980-01-08 1985-07-23 Biogen N.V. Recombinant DNA molecules and their use in producing human interferon-like polypeptides
US6936694B1 (en) 1982-05-06 2005-08-30 Intermune, Inc. Manufacture and expression of large structural genes
US4492537A (en) 1982-12-10 1985-01-08 Awerkamp John B Fluid-operated oil or water well pump
US4917888A (en) 1985-06-26 1990-04-17 Cetus Corporation Solubilization of immunotoxins for pharmaceutical compositions using polymer conjugation
US4766106A (en) 1985-06-26 1988-08-23 Cetus Corporation Solubilization of proteins for pharmaceutical compositions using polymer conjugation
JP2514950B2 (ja) 1986-03-10 1996-07-10 エフ・ホフマン―ラ ロシユ アーゲー 化学修飾蛋白質，その製造法および中間体
US5595732A (en) 1991-03-25 1997-01-21 Hoffmann-La Roche Inc. Polyethylene-protein conjugates
US5382657A (en) 1992-08-26 1995-01-17 Hoffmann-La Roche Inc. Peg-interferon conjugates
WO1995013090A1 (en) 1993-11-10 1995-05-18 Enzon, Inc. Improved interferon polymer conjugates
US5766582A (en) 1994-10-11 1998-06-16 Schering Corporation Stable, aqueous alfa interferon solution formulations
US5824784A (en) * 1994-10-12 1998-10-20 Amgen Inc. N-terminally chemically modified protein compositions and methods
TW426523B (en) 1995-04-06 2001-03-21 Hoffmann La Roche Interferon solution
US6387365B1 (en) * 1995-05-19 2002-05-14 Schering Corporation Combination therapy for chronic hepatitis C infection
US5908621A (en) * 1995-11-02 1999-06-01 Schering Corporation Polyethylene glycol modified interferon therapy
CA2329474C (en) * 1995-11-02 2002-02-26 Schering Corporation Continuous low-dose cytokine infusion therapy
TW517067B (en) 1996-05-31 2003-01-11 Hoffmann La Roche Interferon conjugates
CA2298543A1 (en) 1997-08-13 1999-02-25 James Barry Loading and release of water-insoluble drugs
ATE206618T1 (de) * 1997-09-21 2001-10-15 Schering Corp Kombinationstherapie zur entfernung von nachweisbarer hcv-rns in patienten mit chronischer hepatitis c-infektion

Also Published As

Publication number Publication date
NZ507621A (en) 2002-11-26
AU2005220271A1 (en) 2005-11-03
DE69901321D1 (de) 2002-05-29
JP5281726B2 (ja) 2013-09-04
DE69901321T2 (de) 2002-12-12
MY129244A (en) 2007-03-30
TWI277424B (en) 2007-04-01
AU3860099A (en) 1999-12-06
BR9910505A (pt) 2001-01-02
IL207259A (en) 2016-08-31
CN1309568A (zh) 2001-08-22
AU2005220271B2 (en) 2005-11-03
KR100694345B1 (ko) 2007-03-12
CZ300540B6 (cs) 2009-06-10
ATE216591T1 (de) 2002-05-15
DK0956861T3 (da) 2002-07-01
EP0956861A1 (en) 1999-11-17
EP0956861B1 (en) 2002-04-24
NO330715B1 (no) 2011-06-20
HU230432B1 (hu) 2016-06-28
HK1021131A1 (en) 2000-06-02
EP1213029A1 (en) 2002-06-12
SK17102000A3 (sk) 2001-05-10
AU2005220271B9 (en) 2010-12-09
WO1999059621A1 (en) 1999-11-25
AU766597B2 (en) 2003-10-16
CZ20004177A3 (cs) 2001-04-11
HUP0103423A3 (en) 2003-11-28
HUP0103423A2 (hu) 2002-01-28
IL139220A (en) 2013-02-28
CA2331823A1 (en) 1999-11-25
JP2002515453A (ja) 2002-05-28
ES2172288T3 (es) 2002-09-16
PT956861E (pt) 2002-08-30
NO20005755L (no) 2001-01-12
EP2305287A1 (en) 2011-04-06
CN1230198C (zh) 2005-12-07
IL139220A0 (en) 2001-11-25
SK288038B6 (en) 2013-01-02
AU2005220271B8 (en) 2010-11-18
AR019551A1 (es) 2002-02-27
JP2011173898A (ja) 2011-09-08
IL207259A0 (en) 2010-12-30
KR20010043624A (ko) 2001-05-25

Similar Documents

Publication Publication Date Title
NO20005755D0 (no) Kombinasjonsterapi omfattende ribavirin og interferon &lt;alfa&gt; i antivirusbehandling av naive pasienter med kronisk hepatitt C- infeksjon
NO20006178L (no) Anvendelse av PEG-IFN-&lt;alfa&gt; og ribavirin for behandling av kronisk hepatitt C
ATE230999T1 (de) Kombinationstherapie zur entfernung von nachweisbarer hcv-rns in patienten mit chronischer hepatitis c-infection
NO975309L (no) Anvendelse av rivavirin og alfa-interferon til behandling av hepatitt C
NO995263L (no) Konjugater av polyetylenglykol og interferon-&lt;alfa&gt; for terapi av infeksjoner
NO20023043L (no) Substituerte oksazolidinoner og deres anvendelse innenfor feltet blodkoagulasjon
WO2002032414A3 (en) Ribavirin-pegylated interferon alfa hcv combination therapy
TR200101085T2 (tr) Kronik hepatit C enfeksiyonlu hastalarda algılanabilir HCV-RNA&#39;nın yok edilmesi için birleşik ribavirin-interferon alfa tedavisi
NO996265D0 (no) Behandling av diabetes med rosiglitazon og insulin
KR960702315A (ko) 혈관 차단 치료에서의 헤모글로빈의 치료적 용도 (Therapeutic Use of Hemoglobin in the Treatment of Blood Vessel Blockage)
FI973185A0 (fi) Melatoniinin käyttö lääkeriippuvuudesta kärsivien potilaiden hoitoon
NO20041685L (no) Fremgangsmate for behandling av hepatitt C-virusinfeksjon hos pasienter med manglende behandlingsrespons
WO2004006843A3 (en) Combination therapies with l-fmau for the treatment of hepatitis b virus infection
DK0859630T3 (da) Kombination af termozolomid og alfa-IFN til behandling af fremskreden cancer
IS5778A (is) Stökkbrigði af mennskri lifrarbólgu B veiru og notkun hennar
NO20026000L (no) Behandling og forebyggelse av hjertelidelser forbundet med insulinresistens
SI1311279T1 (sl) Zdravljenje hepatitisa c s timozinom, interferonom in ribavirinom
GB9621866D0 (en) Materials and methods relating to the diagnosis and prophylactic and therapeutic treatment of hepatitis B virus infection and leprosy

Legal Events

Date Code Title Description
CHAD Change of the owner's name or address (par. 44 patent law, par. patentforskriften)

Owner name: MERCK SHARP AND DOHME CORP

Free format text: NEW ADDRESS: 126 EAST LINCOLN AVENUE, US-NJ07065 RAHWAY, US

MK1K Patent expired