NO20005196L - Substituerte pyrrolidinhydroksamat-metallproteaseinhibitorer - Google Patents
Substituerte pyrrolidinhydroksamat-metallproteaseinhibitorerInfo
- Publication number
- NO20005196L NO20005196L NO20005196A NO20005196A NO20005196L NO 20005196 L NO20005196 L NO 20005196L NO 20005196 A NO20005196 A NO 20005196A NO 20005196 A NO20005196 A NO 20005196A NO 20005196 L NO20005196 L NO 20005196L
- Authority
- NO
- Norway
- Prior art keywords
- protease inhibitors
- substituted pyrrolidine
- metal protease
- hydroxamate
- pyrrolidine hydroxamate
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/46—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with hetero atoms directly attached to the ring nitrogen atom
- C07D207/48—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Rheumatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Cardiology (AREA)
- Ophthalmology & Optometry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Oncology (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Enzymes And Modification Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US8166798P | 1998-04-14 | 1998-04-14 | |
PCT/US1999/007826 WO1999052868A1 (en) | 1998-04-14 | 1999-04-09 | Substituted pyrrolidine hydroxamate metalloprotease inhibitors |
Publications (2)
Publication Number | Publication Date |
---|---|
NO20005196D0 NO20005196D0 (no) | 2000-10-16 |
NO20005196L true NO20005196L (no) | 2000-12-14 |
Family
ID=22165611
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20005196A NO20005196L (no) | 1998-04-14 | 2000-10-16 | Substituerte pyrrolidinhydroksamat-metallproteaseinhibitorer |
Country Status (21)
Country | Link |
---|---|
US (1) | US6329418B1 (es) |
EP (1) | EP1073635A1 (es) |
JP (1) | JP2002511448A (es) |
KR (1) | KR100400507B1 (es) |
CN (1) | CN1297436A (es) |
AR (1) | AR029145A1 (es) |
AU (1) | AU753048B2 (es) |
BR (1) | BR9909620A (es) |
CA (1) | CA2328211A1 (es) |
CO (1) | CO5011039A1 (es) |
HU (1) | HUP0102195A3 (es) |
ID (1) | ID26925A (es) |
IL (1) | IL138738A0 (es) |
NO (1) | NO20005196L (es) |
NZ (1) | NZ507076A (es) |
PE (1) | PE20000425A1 (es) |
PL (1) | PL343529A1 (es) |
SK (1) | SK15462000A3 (es) |
TR (1) | TR200002971T2 (es) |
WO (1) | WO1999052868A1 (es) |
ZA (1) | ZA200005047B (es) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6403632B1 (en) * | 2000-03-01 | 2002-06-11 | Bristol Myers Squibb Pharma Co | Lactam metalloprotease inhibitors |
SI1268418T1 (sl) * | 2000-03-27 | 2006-10-31 | Applied Research Systems | Farmacevtsko aktivni pirolidinski derivati kot bax-inhibitorji |
UA74362C2 (uk) * | 2000-03-27 | 2005-12-15 | Еплайд Рісьорч Системз Ерс Холдінг Н.В. | Фармацевтично активні похідні піролідину |
US8283135B2 (en) | 2000-06-30 | 2012-10-09 | The Procter & Gamble Company | Oral care compositions containing combinations of anti-bacterial and host-response modulating agents |
BR0112656A (pt) | 2000-07-19 | 2003-06-24 | Hoffmann La Roche | Compostos, composições farmacêuticas que contêm os mesmos, utilização desses compostos,: processo para tratamento terapêutico e/ou profilático e processo para a preparação desses compostos |
FR2819252A1 (fr) * | 2001-01-11 | 2002-07-12 | Servier Lab | Nouveaux derives d'acide hydroxamique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
SE0100902D0 (sv) * | 2001-03-15 | 2001-03-15 | Astrazeneca Ab | Compounds |
SE0100903D0 (sv) * | 2001-03-15 | 2001-03-15 | Astrazeneca Ab | Compounds |
ATE394371T1 (de) * | 2001-03-20 | 2008-05-15 | Serono Lab | Pyrrolidinesterderivate mit oxytocinmodulierender wirkung |
SE0103710D0 (sv) * | 2001-11-07 | 2001-11-07 | Astrazeneca Ab | Compounds |
UA78058C2 (en) * | 2002-07-05 | 2007-02-15 | Applied Research Systems | Pyrrolidine derivative as oxitocin antagonists |
SE0202539D0 (sv) | 2002-08-27 | 2002-08-27 | Astrazeneca Ab | Compounds |
GB0221246D0 (en) * | 2002-09-13 | 2002-10-23 | Astrazeneca Ab | Compounds |
CN1294120C (zh) * | 2003-10-21 | 2007-01-10 | 山东大学 | 吡咯烷类基质金属蛋白酶抑制剂及其应用 |
EP1725526B1 (en) * | 2004-02-26 | 2007-12-12 | Laboratoires Serono SA | Method for preparing pyrrolidine oximes |
SE0401762D0 (sv) * | 2004-07-05 | 2004-07-05 | Astrazeneca Ab | Novel compounds |
US7648992B2 (en) | 2004-07-05 | 2010-01-19 | Astrazeneca Ab | Hydantoin derivatives for the treatment of obstructive airway diseases |
WO2006038265A1 (ja) * | 2004-09-30 | 2006-04-13 | Yutaka Imauchi | 耳硬化症治療のための医薬組成物 |
SE0403086D0 (sv) * | 2004-12-17 | 2004-12-17 | Astrazeneca Ab | Compounds |
SE0403085D0 (sv) * | 2004-12-17 | 2004-12-17 | Astrazeneca Ab | Novel componds |
TW200831488A (en) * | 2006-11-29 | 2008-08-01 | Astrazeneca Ab | Novel compounds |
AR077214A1 (es) | 2009-06-24 | 2011-08-10 | Neurocrine Biosciences Inc | Heterociclos nitrogenados y composiciones farmaceuticas que los contienen |
TW201111361A (en) | 2009-06-24 | 2011-04-01 | Boehringer Ingelheim Int | New compounds, pharmaceutical composition and methods relating thereto |
EP2845850A1 (en) | 2013-09-10 | 2015-03-11 | ObsEva S.A. | Pyrrolidine derivatives as oxytocin/vasopressin V1a receptors antagonists |
EP2886107A1 (en) | 2013-12-17 | 2015-06-24 | ObsEva S.A. | Oral formulations of pyrrolydine derivatives |
EP3164384B1 (en) | 2014-07-02 | 2019-12-04 | ObsEva S.A. | Crystalline (3z,5s)-5-(hydroxymethyl)-1-[(2'-methyl-1,1'-biphenyl-4-yl)carbonyl]pyrrolidin-3-one o-methyloxime useful in methods of treating conditions related to the ot-r activity |
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US3380992A (en) * | 1965-06-14 | 1968-04-30 | Upjohn Co | Lincomycin derivatives and process for preparing same |
US4377701A (en) * | 1981-09-21 | 1983-03-22 | E. R. Squibb & Sons, Inc. | 4-Methylene-1-[[(alranoyl or arylcarbonyl)mercapto]acyl]proline and pipecolic acid |
US4743587A (en) | 1985-09-10 | 1988-05-10 | G. D. Searle & Co. | Hydroxamic acid based collagenase inhibitors |
US4771038A (en) | 1986-01-21 | 1988-09-13 | Ici Americas Inc. | Hydroxamic acids |
DK77487A (da) | 1986-03-11 | 1987-09-12 | Hoffmann La Roche | Hydroxylaminderivater |
ZW23187A1 (en) | 1986-12-15 | 1988-06-29 | Hoffmann La Roche | Phosphinic acid derivatives |
US5892112A (en) | 1990-11-21 | 1999-04-06 | Glycomed Incorporated | Process for preparing synthetic matrix metalloprotease inhibitors |
US5183900A (en) | 1990-11-21 | 1993-02-02 | Galardy Richard E | Matrix metalloprotease inhibitors |
GB9102635D0 (en) | 1991-02-07 | 1991-03-27 | British Bio Technology | Compounds |
GB9107368D0 (en) | 1991-04-08 | 1991-05-22 | Smithkline Beecham Plc | Novel compounds |
WO1992022523A2 (en) | 1991-06-14 | 1992-12-23 | Research Corporation Technologies, Inc. | Peptide derivatives of collagenase inhibitor |
JPH05125029A (ja) | 1991-11-06 | 1993-05-21 | Yamanouchi Pharmaceut Co Ltd | 新規なアミド化合物又はその塩 |
WO1993014112A1 (en) | 1992-01-15 | 1993-07-22 | Merck & Co., Inc. | Substituted phosphinic acid-containing peptidyl derivatives as antidegenerative agents |
AU4267293A (en) | 1992-05-01 | 1993-11-29 | British Biotech Pharmaceuticals Limited | Use of MMP inhibitors |
US5318964A (en) | 1992-06-11 | 1994-06-07 | Hoffmann-La Roche Inc. | Hydroxamic derivatives and pharmaceutical compositions |
AU666727B2 (en) | 1992-06-25 | 1996-02-22 | F. Hoffmann-La Roche Ag | Hydroxamic acid derivatives |
GB9215665D0 (en) | 1992-07-23 | 1992-09-09 | British Bio Technology | Compounds |
GB9223904D0 (en) | 1992-11-13 | 1993-01-06 | British Bio Technology | Inhibition of cytokine production |
US5455258A (en) | 1993-01-06 | 1995-10-03 | Ciba-Geigy Corporation | Arylsulfonamido-substituted hydroxamic acids |
US5506242A (en) | 1993-01-06 | 1996-04-09 | Ciba-Geigy Corporation | Arylsufonamido-substituted hydroxamic acids |
DE69419473T2 (de) | 1993-04-27 | 2000-03-16 | Celltech Therapeutics Ltd. | Peptidylderivate als inhibitoren von metalloproteinase |
GB9308695D0 (en) | 1993-04-27 | 1993-06-09 | Celltech Ltd | Peptidyl derivatives |
US5827890A (en) | 1993-08-02 | 1998-10-27 | Celltech Therapeutics Ltd. | Succinamide derivatives, processes for their preparation and their use as gelatinase and collagenase inhibitors |
GB9316162D0 (en) * | 1993-08-04 | 1993-09-22 | Zeneca Ltd | Fungicides |
US5545735A (en) | 1993-10-04 | 1996-08-13 | Merck & Co., Inc. | Benzo-Fused Lactams promote release of growth hormone |
US5470834A (en) | 1993-10-06 | 1995-11-28 | Florida State University | Sulfoximine and suldodiimine matrix metalloproteinase inhibitors |
US5403952A (en) | 1993-10-08 | 1995-04-04 | Merck & Co., Inc. | Substituted cyclic derivatives as novel antidegenerative agents |
UA48121C2 (uk) | 1993-11-04 | 2002-08-15 | Сінтекс (С.Ш.А.) Інк. | Інгібітори матричних металопротеаз і фармацетична композиція на їх основі |
GB9323165D0 (en) | 1993-11-10 | 1994-01-05 | Chiros Ltd | Compounds |
DK0822186T3 (da) | 1994-01-20 | 2000-06-26 | British Biotech Pharm | L-tert-leucin-2-pyridylamid |
GB9401129D0 (en) | 1994-01-21 | 1994-03-16 | British Bio Technology | Hydroxamic acid derivatives as metalloproteinase inhibitors |
EP0905126B1 (en) | 1994-01-22 | 2002-12-04 | British Biotech Pharmaceuticals Limited | Metalloproteinase inhibitors |
US5514716A (en) | 1994-02-25 | 1996-05-07 | Sterling Winthrop, Inc. | Hydroxamic acid and carboxylic acid derivatives, process for their preparation and use thereof |
GB9404046D0 (en) | 1994-03-03 | 1994-04-20 | Smithkline Beecham Corp | Novel compounds |
GB9405076D0 (en) | 1994-03-16 | 1994-04-27 | Inst Of Ophtalmology | A medical use of matrix metalloproteinase inhibitors |
DE4411311A1 (de) | 1994-03-31 | 1995-10-05 | Basf Ag | Verfahren zur Herstellung von lagerstabilen wäßrigen Lösungen von Vinylamin-Einheiten enthaltenden Polymerisaten |
GB9501737D0 (en) | 1994-04-25 | 1995-03-22 | Hoffmann La Roche | Hydroxamic acid derivatives |
AU2394795A (en) | 1994-04-28 | 1995-11-29 | Du Pont Merck Pharmaceutical Company, The | Hydroxamic acid and amino acid derivatives and their use as anti-arthritic agents |
JPH07304770A (ja) | 1994-05-11 | 1995-11-21 | Kanebo Ltd | 新規ベンゾアゼピノン誘導体 |
EP0763012B1 (en) | 1994-05-28 | 1999-06-09 | British Biotech Pharmaceuticals Limited | Succinyl hydroxamic acid, n-formyl-n-hydroxy amino carboxylic acid and succinic acid amide derivatives as metalloprotease inhibitors |
GB9411088D0 (en) | 1994-06-03 | 1994-07-27 | Hoffmann La Roche | Hydroxylamine derivatives |
GB9411598D0 (en) | 1994-06-09 | 1994-08-03 | Hoffmann La Roche | Hydroxamic acid derivatives |
GB9412350D0 (en) | 1994-06-20 | 1994-08-10 | Fujisawa Pharmaceutical Co | New compound and its preparation |
GB2303850B (en) | 1994-06-22 | 1998-06-10 | British Biotech Pharm | Metalloproteinase inhibitors |
GB9416897D0 (en) | 1994-08-20 | 1994-10-12 | British Biotech Pharm | Metalloproteinase inhibitors |
AU725831C (en) | 1995-12-08 | 2002-10-17 | Agouron Pharmaceuticals, Inc. | Metalloproteinase inhibitors, pharmaceutical compositions containing them and their pharmaceutical uses, and methods and intermediates useful for their preparation |
JP3541043B2 (ja) | 1996-08-28 | 2004-07-07 | ザ プロクター アンド ギャンブル カンパニー | 置換環状アミンメタロプロテアーゼ阻害剤 |
-
1999
- 1999-03-23 US US09/274,564 patent/US6329418B1/en not_active Expired - Fee Related
- 1999-04-09 KR KR10-2000-7011405A patent/KR100400507B1/ko not_active IP Right Cessation
- 1999-04-09 EP EP99917387A patent/EP1073635A1/en not_active Withdrawn
- 1999-04-09 ID IDW20002350A patent/ID26925A/id unknown
- 1999-04-09 HU HU0102195A patent/HUP0102195A3/hu unknown
- 1999-04-09 AU AU35522/99A patent/AU753048B2/en not_active Ceased
- 1999-04-09 IL IL13873899A patent/IL138738A0/xx unknown
- 1999-04-09 CA CA002328211A patent/CA2328211A1/en not_active Abandoned
- 1999-04-09 SK SK1546-2000A patent/SK15462000A3/sk unknown
- 1999-04-09 WO PCT/US1999/007826 patent/WO1999052868A1/en not_active Application Discontinuation
- 1999-04-09 TR TR2000/02971T patent/TR200002971T2/xx unknown
- 1999-04-09 CN CN99805010A patent/CN1297436A/zh active Pending
- 1999-04-09 PL PL99343529A patent/PL343529A1/xx unknown
- 1999-04-09 BR BR9909620-0A patent/BR9909620A/pt not_active IP Right Cessation
- 1999-04-09 NZ NZ507076A patent/NZ507076A/xx unknown
- 1999-04-09 JP JP2000543431A patent/JP2002511448A/ja not_active Withdrawn
- 1999-04-14 AR ARP990101724A patent/AR029145A1/es not_active Application Discontinuation
- 1999-04-14 CO CO99022198A patent/CO5011039A1/es unknown
- 1999-04-14 PE PE1999000301A patent/PE20000425A1/es not_active Application Discontinuation
-
2000
- 2000-09-21 ZA ZA200005047A patent/ZA200005047B/en unknown
- 2000-10-16 NO NO20005196A patent/NO20005196L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
NZ507076A (en) | 2003-04-29 |
KR100400507B1 (ko) | 2003-10-08 |
TR200002971T2 (tr) | 2001-02-21 |
WO1999052868A1 (en) | 1999-10-21 |
IL138738A0 (en) | 2001-10-31 |
HUP0102195A2 (hu) | 2001-11-28 |
PE20000425A1 (es) | 2000-07-13 |
CN1297436A (zh) | 2001-05-30 |
KR20010042694A (ko) | 2001-05-25 |
AU3552299A (en) | 1999-11-01 |
BR9909620A (pt) | 2000-12-19 |
HUP0102195A3 (en) | 2001-12-28 |
US6329418B1 (en) | 2001-12-11 |
CA2328211A1 (en) | 1999-10-21 |
JP2002511448A (ja) | 2002-04-16 |
AR029145A1 (es) | 2003-06-18 |
ID26925A (id) | 2001-02-22 |
ZA200005047B (en) | 2001-06-06 |
NO20005196D0 (no) | 2000-10-16 |
AU753048B2 (en) | 2002-10-03 |
CO5011039A1 (es) | 2001-02-28 |
SK15462000A3 (sk) | 2001-06-11 |
EP1073635A1 (en) | 2001-02-07 |
PL343529A1 (en) | 2001-08-27 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC2A | Withdrawal, rejection or dismissal of laid open patent application |