NO20004953L - Triazolpurinderivater, farmasöytisk sammensetning inneholdende derivatene, adenosin-A3-reseptor ligand og astmamiddel - Google Patents

Triazolpurinderivater, farmasöytisk sammensetning inneholdende derivatene, adenosin-A3-reseptor ligand og astmamiddel

Info

Publication number
NO20004953L
NO20004953L NO20004953A NO20004953A NO20004953L NO 20004953 L NO20004953 L NO 20004953L NO 20004953 A NO20004953 A NO 20004953A NO 20004953 A NO20004953 A NO 20004953A NO 20004953 L NO20004953 L NO 20004953L
Authority
NO
Norway
Prior art keywords
derivatives
adenosine
composition containing
triazolpurine
pharmaceutical composition
Prior art date
Application number
NO20004953A
Other languages
English (en)
Other versions
NO20004953D0 (no
NO317709B1 (no
Inventor
Takashi Okamura
Yasuhisa Kurogi
Hiroshi Nishikawa
Original Assignee
Otsuka Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd
Publication of NO20004953D0 publication Critical patent/NO20004953D0/no
Publication of NO20004953L publication Critical patent/NO20004953L/no
Publication of NO317709B1 publication Critical patent/NO317709B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/10—Expectorants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/14—Antitussive agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/04—Antipruritics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Molecular Biology (AREA)
  • Cardiology (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Immunology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
NO20004953A 1998-04-03 2000-10-02 Triazolpurinderivater, farmasoytisk sammensetning inneholdende derivatene, adenosin-A3-reseptor ligand og astmamiddel NO317709B1 (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP9136798 1998-04-03
JP28919498 1998-10-12
PCT/JP1999/001592 WO1999051606A1 (fr) 1998-04-03 1999-03-26 Derives de triazolopurine, composition medicinale contenant lesdits derives, agent de compatibilisation de recepteur de l'adenosine a3, et medicament contre l'asthme

Publications (3)

Publication Number Publication Date
NO20004953D0 NO20004953D0 (no) 2000-10-02
NO20004953L true NO20004953L (no) 2000-11-28
NO317709B1 NO317709B1 (no) 2004-12-06

Family

ID=26432810

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20004953A NO317709B1 (no) 1998-04-03 2000-10-02 Triazolpurinderivater, farmasoytisk sammensetning inneholdende derivatene, adenosin-A3-reseptor ligand og astmamiddel

Country Status (13)

Country Link
US (1) US6288070B1 (no)
EP (1) EP1069126B1 (no)
JP (1) JP4077155B2 (no)
KR (1) KR100513062B1 (no)
CN (1) CN1122033C (no)
AT (1) ATE241629T1 (no)
AU (1) AU760399B2 (no)
CA (1) CA2326716C (no)
DE (1) DE69908335T2 (no)
ES (1) ES2195545T3 (no)
NO (1) NO317709B1 (no)
TW (1) TW553945B (no)
WO (1) WO1999051606A1 (no)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU768520B2 (en) * 1999-09-28 2003-12-18 Otsuka Pharmaceutical Factory, Inc. Triazolopurine derivatives, drug compositions containing the same and adenosine A3 receptor affinitive agents
CN1491227A (zh) * 2001-02-05 2004-04-21 株式会社大V制药工厂 三唑并喹唑啉和吡唑并三唑并嘧啶衍生物、医药组合物、腺苷 a 3受体亲和剂、降眼压剂、预防和治疗青光眼的制剂及降低眼压的方法
HUP0401777A3 (en) * 2001-10-15 2008-06-30 Schering Corp 3h-[1,2,4]triazolo[5,1-i]purin-5-yl amines as adenosine a2a receptor antagonists and pharmaceutical compositions containing the compounds
US9199102B2 (en) 2009-07-21 2015-12-01 Oradin Pharmaceutical Ltd. A3 adenosine receptor ligands for modulation of pigmentation
CN111770926B (zh) 2018-01-04 2023-07-21 因佩蒂斯生物科学有限公司 三环化合物、组合物及其医药应用
US11718622B2 (en) 2020-03-16 2023-08-08 Exelixis Inc. Heterocyclic adenosine receptor antagonists

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0217748B1 (en) * 1985-09-30 1991-02-06 Ciba-Geigy Ag 2-Substituted-e-fused-[1,2,4,]triazolo-[1,5-c]pyrimidines pharmaceutical compositions and uses thereof
WO1988002370A1 (en) * 1986-09-30 1988-04-07 Ciba-Geigy Ag 2-substituted-e-fused-[1,2,4]triazolo[1,5-c]pyrimidines pharmaceutical compositions and uses thereof
IT1277392B1 (it) * 1995-07-28 1997-11-10 Schering Plough S P A Analoghi eterociclici di 1,2,4-triazolo(1,5-c]pirimidine ad attivita' antagonista per il recettore a2a dell'adenosina
EP0884318A4 (en) * 1996-10-07 2002-10-23 Kyowa Hakko Kogyo Kk CONDENSED PURINE DERIVATIVES

Also Published As

Publication number Publication date
KR20010042240A (ko) 2001-05-25
DE69908335T2 (de) 2004-04-29
WO1999051606A1 (fr) 1999-10-14
ES2195545T3 (es) 2003-12-01
NO20004953D0 (no) 2000-10-02
DE69908335D1 (de) 2003-07-03
EP1069126A4 (en) 2002-03-27
NO317709B1 (no) 2004-12-06
EP1069126B1 (en) 2003-05-28
AU760399B2 (en) 2003-05-15
CN1301266A (zh) 2001-06-27
TW553945B (en) 2003-09-21
KR100513062B1 (ko) 2005-09-05
CA2326716A1 (en) 1999-10-14
JP4077155B2 (ja) 2008-04-16
ATE241629T1 (de) 2003-06-15
AU2856899A (en) 1999-10-25
CA2326716C (en) 2006-12-12
EP1069126A1 (en) 2001-01-17
CN1122033C (zh) 2003-09-24
US6288070B1 (en) 2001-09-11

Similar Documents

Publication Publication Date Title
DK0801067T3 (da) Hidtil ukendte quinuclidinderivater og medicinsk præparat deraf
DE69002248T2 (de) 1,2-Cyclohexylaminoarylamide zu Verwendung als Analgetika.
LU90266I2 (fr) Composition comprenant du losartan potassium et du hydrochlorothiazide ou leurs dérivés pharmaceutiquement acceptables (hyzaarÐ)
DE69223914T2 (de) 4-substituierte-2-Deoxy-2,3-Didehydro Alpha-D-Neuraminsäure antivirale Derivate
ATE178332T1 (de) Benzothiadiazinderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zuzammensetzungen
NO20004953L (no) Triazolpurinderivater, farmasöytisk sammensetning inneholdende derivatene, adenosin-A3-reseptor ligand og astmamiddel
DK0870761T3 (da) Thiocolchicinderivater med antiinflammatoriske og muskelafslppende aktiviteter
ATE172976T1 (de) 3-aminochroman-spiroderivate, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzungen
NO304694B1 (no) Glukopyranosidbenzotiofener, anvendelse derav for fremstilling av medikamenter samt famasoytisk preparat inneholdende forbindelsen
DK1086071T3 (da) Hyperforinforbindelser, anvendelse heraf og formuleringer indeholdende disse
FI852743A0 (fi) Acetyleniska fenoxipropanolderivat och farmaceutiska kompositioner foer behandling av hypertoni.
ATE123497T1 (de) Substituierte pyridin-verbindungen, ihre herstellung und sie enthaltende pharmazeutische zusammensetzungen.
DE59004292D1 (de) Renin-hemmende Aminooligohydroxy-Derivate.
DK378087D0 (da) Tetracycliske indolderivater
DK0418990T3 (da) 13-brom- og 13,14-dibrom-ergoliner, deres fremstilling og anvendelse i lægemidler
ATE265459T1 (de) Triazolpurin-derivate, medikamentzusammensetzungen, die diese enthalten und mittel, die affinität zum adenosin a3 rezeptor zeigen
SE9803280D0 (sv) Novel compounds
BR0012592A (pt) Composto, uso dos compostos, combinação, e, preparação farmacêutica para uso oral ou parenteral
DE69528984T2 (de) Hemmung der leukotrienbiosynthese mittels harnstoffderivaten
BR9503844A (pt) (R)-7-acetil-5-(4-aminofenil)-8,9-dihidro-8-metil-7h-1, 3-dioco(4,5-h)(2,3) benzodiazepina processo para sua preparação composição farmacêutica e uso
DK0635491T3 (da) (Thia)cycloalkylab indoler, fremgangsmåde til fremstilling heraf og farmaceutiske sammensætninger indeholdende disse forbindelser.
CA2264372A1 (fr) Nouveaux composes du benzocyclobutane, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
DE69419083D1 (de) Salmycine, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
SE9803279D0 (sv) Novel compounds

Legal Events

Date Code Title Description
MM1K Lapsed by not paying the annual fees