NO20003273L - Substituerte <beta>-alaniner - Google Patents

Substituerte <beta>-alaniner

Info

Publication number
NO20003273L
NO20003273L NO20003273A NO20003273A NO20003273L NO 20003273 L NO20003273 L NO 20003273L NO 20003273 A NO20003273 A NO 20003273A NO 20003273 A NO20003273 A NO 20003273A NO 20003273 L NO20003273 L NO 20003273L
Authority
NO
Norway
Prior art keywords
beta
compounds
prodrugs
halogen
hydrogen
Prior art date
Application number
NO20003273A
Other languages
English (en)
Other versions
NO20003273D0 (no
Inventor
Peter Charles Astles
Neil Victor Harris
Andrew David Morley
Original Assignee
Aventis Pharma Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9727532.5A external-priority patent/GB9727532D0/en
Application filed by Aventis Pharma Ltd filed Critical Aventis Pharma Ltd
Publication of NO20003273D0 publication Critical patent/NO20003273D0/no
Publication of NO20003273L publication Critical patent/NO20003273L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24Oxygen or sulfur atoms
    • C07D207/262-Pyrrolidones
    • C07D207/2632-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms
    • C07D207/272-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/28Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C275/42Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by carboxyl groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Rheumatology (AREA)
  • Oncology (AREA)
  • Dermatology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Hydrogenated Pyridines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Polyamides (AREA)
  • Peptides Or Proteins (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Pyridine Compounds (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Pyrrole Compounds (AREA)
NO20003273A 1997-12-23 2000-06-22 Substituerte <beta>-alaniner NO20003273L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9727532.5A GB9727532D0 (en) 1997-12-23 1997-12-23 Chemical compounds
US9260298P 1998-07-13 1998-07-13
PCT/GB1998/003859 WO1999033789A1 (en) 1997-12-23 1998-12-23 SUBSTITUTED β-ALANINES

Publications (2)

Publication Number Publication Date
NO20003273D0 NO20003273D0 (no) 2000-06-22
NO20003273L true NO20003273L (no) 2000-06-22

Family

ID=26312873

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20003273A NO20003273L (no) 1997-12-23 2000-06-22 Substituerte <beta>-alaniner

Country Status (19)

Country Link
EP (1) EP1042279B1 (no)
JP (1) JP4555469B2 (no)
KR (1) KR20010033520A (no)
CN (1) CN1163477C (no)
AT (1) ATE289991T1 (no)
AU (1) AU747907B2 (no)
BR (1) BR9814376A (no)
CA (1) CA2316235A1 (no)
CZ (1) CZ20002342A3 (no)
DE (1) DE69829215T2 (no)
ES (1) ES2235383T3 (no)
HK (1) HK1034508A1 (no)
HU (1) HUP0101701A3 (no)
IL (1) IL136584A (no)
NO (1) NO20003273L (no)
NZ (1) NZ505363A (no)
SK (1) SK9372000A3 (no)
TR (1) TR200001947T2 (no)
WO (1) WO1999033789A1 (no)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4564654B2 (ja) * 1998-01-23 2010-10-20 ノバルティス アーゲー Vla−4アンタゴニスト
AU1881900A (en) * 1998-12-23 2000-07-31 Aventis Pharma Limited Dihydro-benzo(1,4)oxazines and tetrahydroquinoxalines
BR0008280A (pt) * 1999-02-18 2001-11-06 Hoffmann La Roche Derivados de tioamida
NZ518886A (en) 1999-12-28 2004-02-27 Pfizer Prod Inc Non-peptidyl inhibitors of VLA-4 dependent cell binding useful in treating inflammatory, autoimmune, and respiratory diseases
DE10019755A1 (de) * 2000-04-20 2001-11-08 Bayer Ag Neue Aminoaryl/cycloalkylcarbonsäuren als Integrinantagonisten
FR2812633A1 (fr) * 2000-08-04 2002-02-08 Aventis Cropscience Sa Derives de phenyl(thio)urees et phenyl(thio)carbamates fongicides
GB2367816A (en) 2000-10-09 2002-04-17 Bayer Ag Urea- and thiourea-containing derivatives of beta-amino acids
GB2369357A (en) * 2000-10-09 2002-05-29 Bayer Ag Aliphatic, cyclic amino carboxylic acids as integrin antagonists
MXPA03003829A (es) 2000-11-04 2003-07-28 Aventis Pharma Ltd Acidos alcanoicos substituidos.
TWI312779B (no) 2000-12-28 2009-08-01 Daiichi Seiyaku Co
GB2377933A (en) 2001-07-06 2003-01-29 Bayer Ag Succinic acid derivatives useful as integrin antagonists
MXPA06000850A (es) 2003-07-24 2006-03-30 Daiichi Seiyaku Co Compuesto de acido ciclohexancarboxilico.
US20100261796A1 (en) * 2005-04-28 2010-10-14 Ferring B.V. Use of Novel Compounds for IBD Treatment
WO2007069635A1 (ja) 2005-12-13 2007-06-21 Daiichi Sankyo Company, Limited Vla-4阻害薬
CA2714335A1 (en) 2007-02-20 2008-08-28 Merrimack Pharmaceuticals, Inc. Methods of treating multiple sclerosis by administration of alpha-fetoprotein in combination with an integrin antagonist

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6306840B1 (en) * 1995-01-23 2001-10-23 Biogen, Inc. Cell adhesion inhibitors
DE69613985T2 (de) * 1995-08-30 2002-06-13 G.D. Searle & Co., Chicago Meta-guanidine, harnstoff, thioharnstoff oder azacyklische aminobenzoesäure-derivate als integrin antagonisten
WO1997036859A1 (en) * 1996-03-29 1997-10-09 G.D. Searle & Co. Para-substituted phenylpropanoic acid derivatives as integrin antagonists
DE69706407T2 (de) * 1996-03-29 2002-05-29 G.D. Searle & Co., Chicago META-SUBSTITUIERTE PHENYLENDERIVATE UND IHRE VERWENDUNG ALS ALPHAvBETA3 INTERGRIN-ANTAGONISTEN ODER INHIBITOREN
PL340261A1 (en) * 1997-10-31 2001-01-29 Aventis Pharma Ltd Substituted amilides

Also Published As

Publication number Publication date
AU1771999A (en) 1999-07-19
HUP0101701A3 (en) 2003-02-28
HUP0101701A2 (hu) 2001-11-28
NZ505363A (en) 2005-02-25
DE69829215T2 (de) 2005-07-21
CN1283181A (zh) 2001-02-07
EP1042279A1 (en) 2000-10-11
JP2001527061A (ja) 2001-12-25
CA2316235A1 (en) 1999-07-08
EP1042279B1 (en) 2005-03-02
NO20003273D0 (no) 2000-06-22
CN1163477C (zh) 2004-08-25
DE69829215D1 (de) 2005-04-07
BR9814376A (pt) 2000-10-10
WO1999033789A1 (en) 1999-07-08
HK1034508A1 (en) 2001-10-26
IL136584A (en) 2005-03-20
TR200001947T2 (tr) 2001-01-22
ES2235383T3 (es) 2005-07-01
CZ20002342A3 (cs) 2001-11-14
IL136584A0 (en) 2001-06-14
SK9372000A3 (en) 2002-03-05
AU747907B2 (en) 2002-05-30
KR20010033520A (ko) 2001-04-25
JP4555469B2 (ja) 2010-09-29
ATE289991T1 (de) 2005-03-15

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