NO20000257L - Modifisert immunogent pneumolysin, sammensetninger omfattende dette samt anvendelse derav som vaksine - Google Patents
Modifisert immunogent pneumolysin, sammensetninger omfattende dette samt anvendelse derav som vaksineInfo
- Publication number
- NO20000257L NO20000257L NO20000257A NO20000257A NO20000257L NO 20000257 L NO20000257 L NO 20000257L NO 20000257 A NO20000257 A NO 20000257A NO 20000257 A NO20000257 A NO 20000257A NO 20000257 L NO20000257 L NO 20000257L
- Authority
- NO
- Norway
- Prior art keywords
- vaccine
- compositions
- modified immunogenic
- pneumolysin
- immunogenic pneumolysin
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
- C07K14/3156—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci from Streptococcus pneumoniae (Pneumococcus)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
- A61K39/092—Streptococcus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6037—Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S424/00—Drug, bio-affecting and body treating compositions
- Y10S424/831—Drug, bio-affecting and body treating compositions involving capsular polysaccharide of bacterium, e.g. polyribosyl ribitol phosphate
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/82—Proteins from microorganisms
- Y10S530/825—Bacteria
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Mycology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Pulmonology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US5330697P | 1997-07-21 | 1997-07-21 | |
US7345698P | 1998-02-02 | 1998-02-02 | |
PCT/US1998/014716 WO1999003884A2 (en) | 1997-07-21 | 1998-07-21 | Modified immunogenic pneumolysin, compositions and their use as vaccines |
Publications (2)
Publication Number | Publication Date |
---|---|
NO20000257D0 NO20000257D0 (no) | 2000-01-19 |
NO20000257L true NO20000257L (no) | 2000-03-21 |
Family
ID=26731692
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20000257A NO20000257L (no) | 1997-07-21 | 2000-01-19 | Modifisert immunogent pneumolysin, sammensetninger omfattende dette samt anvendelse derav som vaksine |
Country Status (9)
Country | Link |
---|---|
US (2) | US6764686B2 (no) |
EP (1) | EP0998557A2 (no) |
JP (1) | JP2001510031A (no) |
KR (1) | KR100619350B1 (no) |
AU (1) | AU740956B2 (no) |
CA (1) | CA2297374A1 (no) |
HU (1) | HUP0002475A3 (no) |
NO (1) | NO20000257L (no) |
WO (1) | WO1999003884A2 (no) |
Families Citing this family (83)
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US8791237B2 (en) | 1994-11-08 | 2014-07-29 | The Trustees Of The University Of Pennsylvania | Compositions and methods for treatment of non-hodgkins lymphoma |
GB9906437D0 (en) * | 1999-03-19 | 1999-05-12 | Smithkline Beecham Biolog | Vaccine |
EP1880735A3 (en) | 1999-03-19 | 2008-03-12 | GlaxoSmithKline Biologicals S.A. | Vaccine |
GB9918319D0 (en) | 1999-08-03 | 1999-10-06 | Smithkline Beecham Biolog | Vaccine composition |
GB0022742D0 (en) * | 2000-09-15 | 2000-11-01 | Smithkline Beecham Biolog | Vaccine |
US8771702B2 (en) | 2001-03-26 | 2014-07-08 | The Trustees Of The University Of Pennsylvania | Non-hemolytic LLO fusion proteins and methods of utilizing same |
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JP2006500963A (ja) | 2002-08-02 | 2006-01-12 | グラクソスミスクライン バイオロジカルズ ソシエテ アノニム | ワクチン組成物 |
WO2004039417A2 (en) | 2002-11-01 | 2004-05-13 | Glaxosmithkline Biologicals S.A. | Drying process |
AU2003291365B2 (en) | 2002-11-07 | 2009-06-11 | Synergy America, Inc. | Compositions and methods for treating or preventing pneumococcal infection |
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WO2005032584A2 (en) | 2003-10-02 | 2005-04-14 | Glaxosmithkline Biologicals S.A. | Pertussis antigens and use thereof in vaccination |
CA2555803A1 (en) * | 2004-02-13 | 2005-08-27 | Sanofi Pasteur Limited | Pneumolysin derivatives |
WO2005108419A1 (en) * | 2004-05-07 | 2005-11-17 | Lea-Ann Kirkham | Mutant cholesterol-binding cytolysin proteins |
GB0410220D0 (en) * | 2004-05-07 | 2004-06-09 | Kirkham Lea Ann | Mutant pneumolysin proteins |
MX2007002180A (es) * | 2004-08-23 | 2007-10-16 | Medarex Inc | Miembro de enlace hacia la pneumolisina. |
GB0421083D0 (en) * | 2004-09-22 | 2004-10-27 | Glaxosmithkline Biolog Sa | Purification process |
GB0505996D0 (en) | 2005-03-23 | 2005-04-27 | Glaxosmithkline Biolog Sa | Fermentation process |
TWI457133B (zh) | 2005-12-13 | 2014-10-21 | Glaxosmithkline Biolog Sa | 新穎組合物 |
GB0607088D0 (en) | 2006-04-07 | 2006-05-17 | Glaxosmithkline Biolog Sa | Vaccine |
AR058592A1 (es) | 2005-12-22 | 2008-02-13 | Glaxosmithkline Biolog Sa | Vacuna |
CA2636566C (en) | 2006-01-17 | 2018-03-13 | Arne Forsgren | A novel surface exposed haemophilus influenzae protein (protein e; pe) |
EP2032158A2 (en) * | 2006-06-15 | 2009-03-11 | Timothy John Mitchell | Adjuvant compositions |
US20090181078A1 (en) | 2006-09-26 | 2009-07-16 | Infectious Disease Research Institute | Vaccine composition containing synthetic adjuvant |
PT2486938T (pt) | 2006-09-26 | 2018-06-12 | Infectious Disease Res Inst | Composição para vacina contendo adjuvante sintético |
KR101151202B1 (ko) | 2006-10-12 | 2012-06-11 | 글락소스미스클라인 바이오로지칼즈 에스.에이. | 수중유 에멀젼 애주번트를 포함하는 백신 |
EP2086582B1 (en) | 2006-10-12 | 2012-11-14 | GlaxoSmithKline Biologicals s.a. | Vaccine comprising an oil in water emulsion adjuvant |
US9717788B2 (en) | 2007-03-02 | 2017-08-01 | Glaxosmithkline Biologicals Sa | Method of inducing an immune response against HIV employing HIV immunogens, adenoviral vectors encoding said immunogens, and adjuvant |
AU2008223951B2 (en) | 2007-03-02 | 2014-03-27 | Glaxosmithkline Biologicals S.A. | Novel method and compositions |
AU2008287286B2 (en) * | 2007-04-13 | 2013-10-10 | The Board Of Regents Of The University Of Oklahoma | Mutants of cholesterol-dependent cytolysins and uses thereof |
CN101883583B (zh) | 2007-06-26 | 2017-05-17 | 葛兰素史密丝克莱恩生物有限公司 | 含有肺炎链球菌荚膜多糖缀合物的疫苗 |
GB0714963D0 (en) | 2007-08-01 | 2007-09-12 | Novartis Ag | Compositions comprising antigens |
EP2612680B1 (en) | 2008-04-16 | 2018-05-23 | GlaxoSmithKline Biologicals SA | Vaccine |
EP2293815A4 (en) * | 2008-05-22 | 2013-04-03 | Childrens Medical Center | SYNERGISTIC IMMUNOGENIC CONJUGATE FUSION-POLYSACCHARIDE PROTEIN |
GB0815872D0 (en) | 2008-09-01 | 2008-10-08 | Pasteur Institut | Novel method and compositions |
US8758766B2 (en) * | 2008-12-24 | 2014-06-24 | The Kingdom of The Netherlands, Represented by The Mininster of Health, Welfare and Sport, on Behalf of The Minster The National Institute of Public Health and The Environment | Modified Streptococcus pneumoniae pneumolysin (PLY) polypeptides |
JP5668049B2 (ja) | 2009-03-24 | 2015-02-12 | ノバルティス アーゲー | 髄膜炎菌h因子結合タンパク質および肺炎球菌糖結合体の組み合わせ |
TWI494125B (zh) | 2009-06-05 | 2015-08-01 | Infectious Disease Res Inst | 合成的葡萄吡喃糖基脂質佐劑 |
US20120237536A1 (en) | 2009-09-10 | 2012-09-20 | Novartis | Combination vaccines against respiratory tract diseases |
WO2011112717A1 (en) | 2010-03-09 | 2011-09-15 | Biomedical Research Models, Inc. | A novel mucosal vaccination approach for herpes simplex virus type-2 |
GB201003924D0 (en) | 2010-03-09 | 2010-04-21 | Glaxosmithkline Biolog Sa | Immunogenic composition |
JP2013521770A (ja) | 2010-03-10 | 2013-06-13 | グラクソスミスクライン バイオロジカルズ ソシエテ アノニム | ワクチン組成物 |
WO2011112906A2 (en) | 2010-03-12 | 2011-09-15 | Children's Medical Center Corporation | Novel immunogens and methods for discovery and screening thereof |
WO2011130434A2 (en) | 2010-04-13 | 2011-10-20 | Celldex Therapeutics Inc. | Antibodies that bind human cd27 and uses thereof |
GB201015132D0 (en) | 2010-09-10 | 2010-10-27 | Univ Bristol | Vaccine composition |
WO2012072769A1 (en) | 2010-12-01 | 2012-06-07 | Novartis Ag | Pneumococcal rrgb epitopes and clade combinations |
BR112013013702A2 (pt) | 2010-12-03 | 2016-09-13 | Sanofi Pasteur Ltd | composição para imunização contra streptococcus pneumoniae |
GB201022007D0 (en) | 2010-12-24 | 2011-02-02 | Imp Innovations Ltd | DNA-sensor |
AU2012243039B2 (en) | 2011-04-08 | 2017-07-13 | Immune Design Corp. | Immunogenic compositions and methods of using the compositions for inducing humoral and cellular immune responses |
US20140072622A1 (en) | 2011-05-17 | 2014-03-13 | Glaxosmithkline Biologicals S.A. | Vaccine against streptococcus pneumoniae |
US20140294930A1 (en) | 2011-08-04 | 2014-10-02 | The Regents Of The University Of California | STREPTOCOCCAL GlcNAc-LACKING GLYCOPOLYPEPTIDES, CELL WALL CARBOHYDRATES, STREPTOCOCCUS VACCINES, AND METHODS FOR MAKING AND USING THEM |
PL2811981T3 (pl) | 2012-02-07 | 2019-09-30 | Infectious Disease Research Institute | Ulepszone formulacje adiuwantowe zawierające agonistę TLR4 oraz sposoby ich zastosowania |
JP2015510872A (ja) | 2012-03-07 | 2015-04-13 | ノバルティス アーゲー | Streptococcuspneumoniae抗原の増強された製剤 |
EA034351B1 (ru) | 2012-05-16 | 2020-01-30 | Иммьюн Дизайн Корп. | Трехкомпонентная вакцина против впг-2 и способы ее применения |
US20140193451A1 (en) * | 2012-10-17 | 2014-07-10 | Glaxosmithkline Biologicals Sa | Immunogenic composition |
US9566325B2 (en) | 2013-01-07 | 2017-02-14 | Biomedical Research Models, Inc. | Therapeutic vaccines for treating herpes simplex virus type-2 infections |
ES2959258T3 (es) | 2013-02-07 | 2024-02-22 | Childrens Medical Center | Antígenos proteicos que proporcionan protección contra la colonización y/o la enfermedad neumocócicas |
BR112015025709A2 (pt) | 2013-04-18 | 2017-07-18 | Immune Design Corp | monoterapia com gla para uso em tratamento de câncer |
US9463198B2 (en) | 2013-06-04 | 2016-10-11 | Infectious Disease Research Institute | Compositions and methods for reducing or preventing metastasis |
PT3089754T (pt) | 2013-12-31 | 2021-07-23 | Infectious Disease Res Inst | Formulações de vacina de dose única |
US9815886B2 (en) | 2014-10-28 | 2017-11-14 | Adma Biologics, Inc. | Compositions and methods for the treatment of immunodeficiency |
CA2968398A1 (en) | 2014-11-21 | 2016-05-26 | The Board Of Regents Of The University Of Oklahoma | Pneumolysin mutants and methods of use thereof |
EP3268037B1 (en) | 2015-03-09 | 2022-08-31 | Celldex Therapeutics, Inc. | Cd27 agonists |
GB201518684D0 (en) | 2015-10-21 | 2015-12-02 | Glaxosmithkline Biolog Sa | Vaccine |
WO2017176076A1 (en) | 2016-04-06 | 2017-10-12 | Ewha University - Industry Collaboration Foundation | A peptide with ability to penetrate cell membrane |
CN109071665B (zh) | 2016-04-18 | 2022-11-01 | 塞德斯医疗公司 | 结合人cd40的激动性抗体及其用途 |
US11344619B2 (en) | 2016-05-16 | 2022-05-31 | Access To Advanced Health Institute | Formulation containing TLR agonist and methods of use |
CA3023672A1 (en) | 2016-05-16 | 2017-11-23 | Infectious Disease Research Institute | Pegylated liposomes and methods of use |
AU2017273650B2 (en) | 2016-06-01 | 2022-08-18 | Access To Advanced Health Institute | Nanoalum particles containing a sizing agent |
GB201610599D0 (en) | 2016-06-17 | 2016-08-03 | Glaxosmithkline Biologicals Sa | Immunogenic Composition |
US10259865B2 (en) | 2017-03-15 | 2019-04-16 | Adma Biologics, Inc. | Anti-pneumococcal hyperimmune globulin for the treatment and prevention of pneumococcal infection |
WO2018175783A1 (en) * | 2017-03-22 | 2018-09-27 | Modernatx, Inc. | Rna bacterial vaccines |
MX2019015076A (es) | 2017-06-15 | 2020-08-03 | Infectious Disease Res Inst | Portadores lípidos nanoestructurados y emulsiones estables y usos de los mismos. |
CA3078223A1 (en) | 2017-09-08 | 2019-03-14 | Infectious Disease Research Institute | Liposomal formulations comprising saponin and methods of use |
US20210198374A1 (en) | 2018-04-17 | 2021-07-01 | Celldex Therapeutics, Inc. | Anti-cd27 and anti-pd-l1 antibodies and bispecific constructs |
BR112021004193A2 (pt) | 2018-09-12 | 2021-05-25 | Affinivax, Inc. | vacinas pneumocócicas multivalentes |
WO2020123444A1 (en) | 2018-12-11 | 2020-06-18 | Celldex Therapeutics, Inc. | Methods of using cd27 antibodies as conditioning treatment for adoptive cell therapy |
EP3894431A2 (en) | 2018-12-12 | 2021-10-20 | GlaxoSmithKline Biologicals SA | Modified carrier proteins for o-linked glycosylation |
MX2021014363A (es) | 2019-05-25 | 2022-02-21 | Infectious Disease Res Inst | Composicion y metodo para secar por pulverizacion una emulsion de vacuna adyuvante. |
CA3174411A1 (en) | 2020-09-04 | 2022-03-10 | Ryan M. Kramer | Co-lyophilized rna and nanostructured lipid carrier |
AU2022253269A1 (en) | 2021-04-09 | 2023-11-23 | Celldex Therapeutics, Inc. | Antibodies against ilt4, bispecific anti-ilt4/pd-l1 antibody and uses thereof |
WO2023077521A1 (en) | 2021-11-08 | 2023-05-11 | Celldex Therapeutics, Inc | Anti-ilt4 and anti-pd-1 bispecific constructs |
WO2024052882A1 (en) | 2022-09-09 | 2024-03-14 | Access To Advanced Health Institute | Immunogenic vaccine composition incorporating a saponin |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2160570T3 (es) * | 1988-12-16 | 2001-11-16 | Nederlanden Staat | Mutantes de neumolisina y vacunas de neumococos fabricadas a partir de los mismos. |
CA2059692C (en) | 1991-01-28 | 2004-11-16 | Peter J. Kniskern | Pneumoccoccal polysaccharide conjugate vaccine |
WO1995016711A1 (es) * | 1993-12-17 | 1995-06-22 | Universidad De Oviedo | Anticuerpos contra la neumolisina y sus aplicaciones |
US5565204A (en) * | 1994-08-24 | 1996-10-15 | American Cyanamid Company | Pneumococcal polysaccharide-recombinant pneumolysin conjugate vaccines for immunization against pneumococcal infections |
US6019982A (en) * | 1994-08-26 | 2000-02-01 | The Administrators Of The Tulane Educational Fund | Mutant enterotoxin effective as a non-toxic oral adjuvant |
CA2262748A1 (en) * | 1996-08-12 | 1998-02-19 | Board Of Regents, The University Of Texas System | Defining epitopes of the outer membrane protein copb of moraxella catarrhalis |
-
1998
- 1998-07-21 HU HU0002475A patent/HUP0002475A3/hu unknown
- 1998-07-21 AU AU84078/98A patent/AU740956B2/en not_active Ceased
- 1998-07-21 US US09/120,044 patent/US6764686B2/en not_active Expired - Fee Related
- 1998-07-21 WO PCT/US1998/014716 patent/WO1999003884A2/en not_active Application Discontinuation
- 1998-07-21 EP EP98934590A patent/EP0998557A2/en not_active Withdrawn
- 1998-07-21 CA CA002297374A patent/CA2297374A1/en not_active Abandoned
- 1998-07-21 JP JP2000503106A patent/JP2001510031A/ja active Pending
- 1998-07-21 KR KR1020007000844A patent/KR100619350B1/ko not_active IP Right Cessation
-
2000
- 2000-01-19 NO NO20000257A patent/NO20000257L/no not_active Application Discontinuation
-
2004
- 2004-02-23 US US10/785,673 patent/US20050070695A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
US20010014332A1 (en) | 2001-08-16 |
KR20010022271A (ko) | 2001-03-15 |
KR100619350B1 (ko) | 2006-09-05 |
AU8407898A (en) | 1999-02-10 |
EP0998557A2 (en) | 2000-05-10 |
NO20000257D0 (no) | 2000-01-19 |
JP2001510031A (ja) | 2001-07-31 |
WO1999003884A2 (en) | 1999-01-28 |
CA2297374A1 (en) | 1999-01-28 |
AU740956B2 (en) | 2001-11-15 |
HUP0002475A3 (en) | 2002-01-28 |
HUP0002475A2 (hu) | 2000-10-28 |
US6764686B2 (en) | 2004-07-20 |
WO1999003884A3 (en) | 1999-04-08 |
US20050070695A1 (en) | 2005-03-31 |
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FC2A | Withdrawal, rejection or dismissal of laid open patent application |