NO179181C - Tredimensjonal stromacellekultur, anvendelse av stromacellekulturen for dyrking av ulike celletyper in vitro, samt anvendelse av cellekulturen for in vitro testing av cytotoksisk eller medikamentell virkning - Google Patents

Tredimensjonal stromacellekultur, anvendelse av stromacellekulturen for dyrking av ulike celletyper in vitro, samt anvendelse av cellekulturen for in vitro testing av cytotoksisk eller medikamentell virkning

Info

Publication number
NO179181C
NO179181C NO875286A NO875286A NO179181C NO 179181 C NO179181 C NO 179181C NO 875286 A NO875286 A NO 875286A NO 875286 A NO875286 A NO 875286A NO 179181 C NO179181 C NO 179181C
Authority
NO
Norway
Prior art keywords
cell culture
vitro
culture
bone marrow
stromal cell
Prior art date
Application number
NO875286A
Other languages
English (en)
Other versions
NO179181B (no
NO875286D0 (no
NO875286L (no
Inventor
Brian A Naughton
Gail K Naughton
Original Assignee
Marrow Tech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/036,154 external-priority patent/US4721096A/en
Application filed by Marrow Tech Inc filed Critical Marrow Tech Inc
Publication of NO875286D0 publication Critical patent/NO875286D0/no
Publication of NO875286L publication Critical patent/NO875286L/no
Publication of NO179181B publication Critical patent/NO179181B/no
Publication of NO179181C publication Critical patent/NO179181C/no

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0697Artificial constructs associating cells of different lineages, e.g. tissue equivalents
    • C12N5/0698Skin equivalents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/60Materials for use in artificial skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
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    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0634Cells from the blood or the immune system
    • C12N5/0647Haematopoietic stem cells; Uncommitted or multipotent progenitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/02Instruments for taking cell samples or for biopsy
    • A61B10/0233Pointed or sharp biopsy instruments
    • A61B10/025Pointed or sharp biopsy instruments for taking bone, bone marrow or cartilage samples
    • A61B2010/0258Marrow samples
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00Coculture with; Conditioned medium produced by
    • C12N2502/09Coculture with; Conditioned medium produced by epidermal cells, skin cells, oral mucosa cells
    • C12N2502/094Coculture with; Conditioned medium produced by epidermal cells, skin cells, oral mucosa cells keratinocytes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00Coculture with; Conditioned medium produced by
    • C12N2502/13Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
    • C12N2502/1323Adult fibroblasts
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2502/00Coculture with; Conditioned medium produced by
    • C12N2502/13Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
    • C12N2502/1394Bone marrow stromal cells; whole marrow
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2510/00Genetically modified cells
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    • C12N2533/00Supports or coatings for cell culture, characterised by material
    • C12N2533/30Synthetic polymers
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    • C12N2533/00Supports or coatings for cell culture, characterised by material
    • C12N2533/30Synthetic polymers
    • C12N2533/40Polyhydroxyacids, e.g. polymers of glycolic or lactic acid (PGA, PLA, PLGA); Bioresorbable polymers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00Supports or coatings for cell culture, characterised by material
    • C12N2533/70Polysaccharides

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Developmental Biology & Embryology (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Surgery (AREA)
  • Microbiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Virology (AREA)
  • Diabetes (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Transplantation (AREA)
  • Pathology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
NO875286A 1986-04-18 1987-12-17 Tredimensjonal stromacellekultur, anvendelse av stromacellekulturen for dyrking av ulike celletyper in vitro, samt anvendelse av cellekulturen for in vitro testing av cytotoksisk eller medikamentell virkning NO179181C (no)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US85356986A 1986-04-18 1986-04-18
US07/036,154 US4721096A (en) 1986-04-18 1987-04-03 Process for replicating bone marrow in vitro and using the same
US3811087A 1987-04-14 1987-04-14
PCT/US1987/000869 WO1987006120A1 (en) 1986-04-18 1987-04-15 Process for replicating bone marrow

Publications (4)

Publication Number Publication Date
NO875286D0 NO875286D0 (no) 1987-12-17
NO875286L NO875286L (no) 1987-12-17
NO179181B NO179181B (no) 1996-05-13
NO179181C true NO179181C (no) 1996-08-21

Family

ID=27364979

Family Applications (1)

Application Number Title Priority Date Filing Date
NO875286A NO179181C (no) 1986-04-18 1987-12-17 Tredimensjonal stromacellekultur, anvendelse av stromacellekulturen for dyrking av ulike celletyper in vitro, samt anvendelse av cellekulturen for in vitro testing av cytotoksisk eller medikamentell virkning

Country Status (15)

Country Link
EP (1) EP0309456B1 (no)
JP (2) JP2857392B2 (no)
KR (1) KR0142885B1 (no)
AT (1) ATE127692T1 (no)
AU (3) AU615414B2 (no)
BG (1) BG51337A3 (no)
BR (1) BR8707673A (no)
DE (1) DE3751519T2 (no)
DK (1) DK665687A (no)
FI (1) FI100249B (no)
HK (1) HK1007684A1 (no)
HU (1) HU202578B (no)
NO (1) NO179181C (no)
RO (1) RO106655B1 (no)
WO (1) WO1987006120A1 (no)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5902741A (en) * 1986-04-18 1999-05-11 Advanced Tissue Sciences, Inc. Three-dimensional cartilage cultures
AU644578B2 (en) * 1986-04-18 1993-12-16 Marrow-Tech Incorporated Three-dimensional cell and tissue culture system
US5736372A (en) * 1986-11-20 1998-04-07 Massachusetts Institute Of Technology Biodegradable synthetic polymeric fibrous matrix containing chondrocyte for in vivo production of a cartilaginous structure
US5759830A (en) * 1986-11-20 1998-06-02 Massachusetts Institute Of Technology Three-dimensional fibrous scaffold containing attached cells for producing vascularized tissue in vivo
US5567612A (en) * 1986-11-20 1996-10-22 Massachusetts Institute Of Technology Genitourinary cell-matrix structure for implantation into a human and a method of making
US6309635B1 (en) 1986-11-20 2001-10-30 Children's Medical Center Corp. Seeding parenchymal cells into compression resistant porous scaffold after vascularizing in vivo
AU2900792A (en) * 1991-10-24 1993-05-21 Children's Medical Center Corporation Neomorphogenesis of urological structures in vivo from cell culture
US5436151A (en) * 1992-04-03 1995-07-25 Regents Of The University Of Minnesota Method for culturing human hematopoietic stem cells in vitro
US5460964A (en) * 1992-04-03 1995-10-24 Regents Of The University Of Minnesota Method for culturing hematopoietic cells
US7214654B1 (en) 1994-12-07 2007-05-08 Karlheinz Schmidt Agent for the manufacture of biological parts including an active ingredient complex and carrying materials suitable for the active ingredient complex
US5709854A (en) * 1993-04-30 1998-01-20 Massachusetts Institute Of Technology Tissue formation by injecting a cell-polymeric solution that gels in vivo
US5855610A (en) 1995-05-19 1999-01-05 Children's Medical Center Corporation Engineering of strong, pliable tissues
US5741685A (en) * 1995-06-07 1998-04-21 Children's Medical Center Corporation Parenchymal cells packaged in immunoprotective tissue for implantation
US5728581A (en) * 1995-06-07 1998-03-17 Systemix, Inc. Method of expanding hematopoietic stem cells, reagents and bioreactors for use therein
WO2000027999A2 (en) * 1998-11-12 2000-05-18 Cell Science Therapeutics, Inc. Lymphoid tissue-specific cell production from hematopoietic progenitor cells in three-dimensional devices
AU759719B2 (en) * 1999-02-04 2003-04-17 Pluristem Ltd. Method and apparatus for maintenance and expansion of hemopoietic stem cells and/or progenitor cells
US7087431B2 (en) 2000-03-02 2006-08-08 University Of Rochester Ex vivo generation of functional leukemia cells in a three-dimensional bioreactor
DE10203644A1 (de) * 2002-01-30 2003-08-07 Fraunhofer Ges Forschung Kryokonservierung an textilen Geweben
EP1718317A1 (en) 2004-02-13 2006-11-08 Intercytex Limited Wound healing profile
NZ560813A (en) * 2005-03-01 2010-04-30 Tata Inst Of Fundamental Res A composition for creating an artificial bone-marrow like environment and use thereof
JP4977854B2 (ja) * 2005-10-21 2012-07-18 国立大学法人名古屋大学 組織形成用複合材料およびその製造方法
JP5669741B2 (ja) * 2008-10-22 2015-02-12 リジーンメッド インコーポレイテッド 培養システム
US9951313B2 (en) * 2011-06-02 2018-04-24 President And Fellows Of Harvard College Methods and uses for ex vivo tissue culture systems

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH593339A5 (no) * 1973-07-02 1977-11-30 Monsanto Co
US4144126A (en) * 1975-05-21 1979-03-13 Beecham Group Limited Cell culture method
JPS51151384A (en) * 1975-06-20 1976-12-25 Olympus Optical Co Ltd Process for cultivating organic tissue or cells automatically
US4024020A (en) * 1975-12-15 1977-05-17 Monsanto Company Method of cell culture on polyacrylonitrile surface
US4184922A (en) * 1977-11-11 1980-01-22 The Government Of The United States Dual circuit, woven artificial capillary bundle for cell culture
US4228243A (en) * 1978-07-13 1980-10-14 Toray Industries, Inc. Cell culture propagation apparatus
IL74715A0 (en) * 1984-03-27 1985-06-30 Univ New Jersey Med Biodegradable matrix and methods for producing same

Also Published As

Publication number Publication date
DE3751519D1 (de) 1995-10-19
EP0309456A4 (en) 1989-06-27
JP2857392B2 (ja) 1999-02-17
BG51337A3 (en) 1993-04-15
JPH01503195A (ja) 1989-11-02
EP0309456B1 (en) 1995-09-13
FI100249B (fi) 1997-10-31
AU615414B2 (en) 1991-10-03
NO179181B (no) 1996-05-13
HU202578B (en) 1991-03-28
AU6815990A (en) 1991-03-14
FI884783A0 (fi) 1988-10-17
WO1987006120A1 (en) 1987-10-22
DK665687D0 (da) 1987-12-17
DE3751519T2 (de) 1996-03-28
JPH10114664A (ja) 1998-05-06
AU7356887A (en) 1987-11-09
DK665687A (da) 1987-12-17
HK1007684A1 (en) 1999-04-23
RO106655B1 (ro) 1993-06-30
KR880701093A (ko) 1988-07-25
KR0142885B1 (ko) 1998-07-15
JP3032492B2 (ja) 2000-04-17
NO875286D0 (no) 1987-12-17
EP0309456A1 (en) 1989-04-05
NO875286L (no) 1987-12-17
HUT48112A (en) 1989-05-29
BR8707673A (pt) 1989-08-15
FI884783A (fi) 1988-10-17
ATE127692T1 (de) 1995-09-15
AU6816090A (en) 1991-03-14

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