NO176761C - Analogifremgangsmåte for fremstilling av terapeutisk aktive P-substituerte aminoalkylfosfinsyrer - Google Patents

Analogifremgangsmåte for fremstilling av terapeutisk aktive P-substituerte aminoalkylfosfinsyrer

Info

Publication number
NO176761C
NO176761C NO902109A NO902109A NO176761C NO 176761 C NO176761 C NO 176761C NO 902109 A NO902109 A NO 902109A NO 902109 A NO902109 A NO 902109A NO 176761 C NO176761 C NO 176761C
Authority
NO
Norway
Prior art keywords
denotes
preparation
hydrogen
therapeutically active
phosphinic acids
Prior art date
Application number
NO902109A
Other languages
English (en)
Norwegian (no)
Other versions
NO902109D0 (no
NO176761B (no
NO902109L (no
Inventor
Roger Graham Hall
Ludwig Maier
Wolfgang Frostl
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of NO902109D0 publication Critical patent/NO902109D0/no
Publication of NO902109L publication Critical patent/NO902109L/no
Publication of NO176761B publication Critical patent/NO176761B/no
Publication of NO176761C publication Critical patent/NO176761C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/30Phosphinic acids [R2P(=O)(OH)]; Thiophosphinic acids ; [R2P(=X1)(X2H) (X1, X2 are each independently O, S or Se)]
    • C07F9/36Amides thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/30Phosphinic acids [R2P(=O)(OH)]; Thiophosphinic acids ; [R2P(=X1)(X2H) (X1, X2 are each independently O, S or Se)]
    • C07F9/301Acyclic saturated acids which can have further substituents on alkyl
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
  • Luminescent Compositions (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Detergent Compositions (AREA)
NO902109A 1989-05-13 1990-05-11 Analogifremgangsmåte for fremstilling av terapeutisk aktive P-substituerte aminoalkylfosfinsyrer NO176761C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB898911017A GB8911017D0 (en) 1989-05-13 1989-05-13 Substituted aminoalkylphosphinic acids

Publications (4)

Publication Number Publication Date
NO902109D0 NO902109D0 (no) 1990-05-11
NO902109L NO902109L (no) 1990-11-14
NO176761B NO176761B (no) 1995-02-13
NO176761C true NO176761C (no) 1995-05-24

Family

ID=10656689

Family Applications (1)

Application Number Title Priority Date Filing Date
NO902109A NO176761C (no) 1989-05-13 1990-05-11 Analogifremgangsmåte for fremstilling av terapeutisk aktive P-substituerte aminoalkylfosfinsyrer

Country Status (24)

Country Link
EP (1) EP0399949B1 (pt)
JP (1) JP2930366B2 (pt)
KR (1) KR0159501B1 (pt)
AT (1) ATE121095T1 (pt)
AU (1) AU629335B2 (pt)
CA (1) CA2016631C (pt)
DD (1) DD294265A5 (pt)
DE (1) DE69018514T2 (pt)
DK (1) DK0399949T3 (pt)
ES (1) ES2070303T3 (pt)
FI (1) FI94416C (pt)
GB (1) GB8911017D0 (pt)
GR (1) GR3015770T3 (pt)
HR (1) HRP940178A2 (pt)
HU (1) HU206885B (pt)
IE (1) IE66165B1 (pt)
IL (1) IL94317A (pt)
MX (1) MX20639A (pt)
NO (1) NO176761C (pt)
NZ (1) NZ233647A (pt)
PT (1) PT94014B (pt)
SI (1) SI9010917B (pt)
YU (1) YU91790A (pt)
ZA (1) ZA903611B (pt)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0767174A1 (de) * 1991-11-21 1997-04-09 Ciba-Geigy Ag Neue Aminoalkanphosphinsäuren und ihre Salze
BR9710536A (pt) 1996-07-24 1999-08-17 Warner Lambert Co Isobutilgaba e seus derivados para o tratamento da dor
EE200100027A (et) 1998-07-15 2002-06-17 Jomaa Hassan Fosfororgaanilised ühendid, neid sisaldav farmatseutiline preparaat ja nende kasutamine
GB9906882D0 (en) * 1999-03-25 1999-05-19 Novartis Ag Organic compounds
US7319095B2 (en) 1999-12-09 2008-01-15 Astrazeneca Ab Use of GABAB receptor agonists
SE9904508D0 (sv) 1999-12-09 1999-12-09 Astra Ab New compounds
SE9904507D0 (sv) * 1999-12-09 1999-12-09 Astra Ab New compounds
AR033779A1 (es) 2001-06-08 2004-01-07 Astrazeneca Ab Compuestos utiles en la enfermedad de reflujo
SE0102055D0 (sv) * 2001-06-08 2001-06-08 Astrazeneca Ab New Compounds
CA2548917C (en) 2003-12-11 2014-09-23 Sepracor Inc. Combination of a sedative and a neurotransmitter modulator, and methods for improving sleep quality and treating depression
SE0401653D0 (sv) 2004-06-24 2004-06-24 Astrazeneca Ab New compounds
CA2632016A1 (en) 2005-12-23 2007-06-28 Astrazeneca Ab Imidazole derivatives for the treatment of gastrointestinal disorders
EP1968947A1 (en) 2005-12-23 2008-09-17 AstraZeneca AB Gaba-b receptor modulators
DE102008056228A1 (de) * 2008-11-06 2010-05-12 Clariant International Limited Verfahren zur Herstellung von monoaminofunktionalisierten Dialkylphosphinsäuren, deren Salze und Ester und ihre Verwendung
DE102008056339A1 (de) * 2008-11-07 2010-05-12 Clariant International Limited Verfahren zur Herstellung von mono-aminofunktionalisierten Dialkylphosphinsäuren, -estern und -salzen und ihre Verwendung
WO2011113904A1 (en) 2010-03-17 2011-09-22 INSERM (Institut National de la Santé et de la Recherche Médicale) Medicaments for the prevention and treatment of a disease associated with retinal ganglion cell degeneration
EP2621282B1 (en) 2010-09-28 2020-04-15 The Regents of The University of California Gaba agonists in the treatment of disorders associated with metabolic syndrome and gaba combinations in treatment or prophylaxis of type i diabetes

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3311475C1 (de) * 1983-03-29 1984-08-16 Siemens AG, 1000 Berlin und 8000 München Mikroprogramm-Steuereinrichtung
DE3312165A1 (de) * 1983-04-02 1984-10-04 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung von phosphinothricin
GB8728483D0 (en) * 1987-12-04 1988-01-13 Ciba Geigy Ag Chemical compounds
GB8820266D0 (en) * 1988-08-26 1988-09-28 Smith Kline French Lab Compounds

Also Published As

Publication number Publication date
GB8911017D0 (en) 1989-06-28
CA2016631C (en) 2000-08-29
SI9010917A (en) 1997-06-30
ATE121095T1 (de) 1995-04-15
ZA903611B (en) 1991-02-27
PT94014B (pt) 1996-12-31
CA2016631A1 (en) 1990-11-13
IE901716L (en) 1990-11-13
EP0399949B1 (en) 1995-04-12
KR900018124A (ko) 1990-12-20
YU91790A (sh) 1992-07-20
IE66165B1 (en) 1995-12-13
PT94014A (pt) 1991-01-08
HUT53656A (en) 1990-11-28
NO902109D0 (no) 1990-05-11
SI9010917B (sl) 1999-10-31
JP2930366B2 (ja) 1999-08-03
EP0399949A1 (en) 1990-11-28
ES2070303T3 (es) 1995-06-01
FI902368A0 (fi) 1990-05-11
MX20639A (es) 1993-12-01
IL94317A0 (en) 1991-03-10
HU903012D0 (en) 1990-09-28
DK0399949T3 (da) 1995-07-03
DE69018514D1 (de) 1995-05-18
DD294265A5 (de) 1991-09-26
AU5480990A (en) 1990-11-15
AU629335B2 (en) 1992-10-01
FI94416B (fi) 1995-05-31
GR3015770T3 (en) 1995-07-31
HRP940178A2 (en) 1996-08-31
HU206885B (en) 1993-01-28
IL94317A (en) 1997-07-13
JPH0395195A (ja) 1991-04-19
KR0159501B1 (ko) 1999-01-15
NO176761B (no) 1995-02-13
DE69018514T2 (de) 1995-09-21
FI94416C (fi) 1995-09-11
NZ233647A (en) 1992-08-26
NO902109L (no) 1990-11-14

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Legal Events

Date Code Title Description
MM1K Lapsed by not paying the annual fees

Free format text: LAPSED IN NOVEMBER 2001