NO171786C - Analogifremgangsmaate for fremstilling av terapeutisk aktive isokinolinderivater - Google Patents

Analogifremgangsmaate for fremstilling av terapeutisk aktive isokinolinderivater

Info

Publication number
NO171786C
NO171786C NO890440A NO890440A NO171786C NO 171786 C NO171786 C NO 171786C NO 890440 A NO890440 A NO 890440A NO 890440 A NO890440 A NO 890440A NO 171786 C NO171786 C NO 171786C
Authority
NO
Norway
Prior art keywords
isoqinoline
derivatives
preparation
therapeutic active
group
Prior art date
Application number
NO890440A
Other languages
English (en)
Norwegian (no)
Other versions
NO890440L (no
NO890440D0 (no
NO171786B (no
Inventor
Pascal George
Mireille Sevrin
Christian Maloizel
Arlette Tixidre
Jacques Froissant
Original Assignee
Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR8809447A external-priority patent/FR2634204B2/fr
Application filed by Synthelabo filed Critical Synthelabo
Publication of NO890440D0 publication Critical patent/NO890440D0/no
Publication of NO890440L publication Critical patent/NO890440L/no
Publication of NO171786B publication Critical patent/NO171786B/no
Publication of NO171786C publication Critical patent/NO171786C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NO890440A 1988-07-12 1989-02-03 Analogifremgangsmaate for fremstilling av terapeutisk aktive isokinolinderivater NO171786C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8809447A FR2634204B2 (fr) 1987-08-07 1988-07-12 Derives de ((piperidinyl-4)methyl)-2 tetrahydro-1,2,3,4 isoquinoleines, leur preparation et leur application en therapeutique

Publications (4)

Publication Number Publication Date
NO890440D0 NO890440D0 (no) 1989-02-03
NO890440L NO890440L (no) 1990-01-15
NO171786B NO171786B (no) 1993-01-25
NO171786C true NO171786C (no) 1993-05-05

Family

ID=9368349

Family Applications (1)

Application Number Title Priority Date Filing Date
NO890440A NO171786C (no) 1988-07-12 1989-02-03 Analogifremgangsmaate for fremstilling av terapeutisk aktive isokinolinderivater

Country Status (15)

Country Link
US (1) US4925850A (fi)
EP (1) EP0351255B1 (fi)
JP (1) JPH0225481A (fi)
KR (1) KR900001676A (fi)
AT (1) ATE95816T1 (fi)
AU (1) AU606778B2 (fi)
DE (1) DE68909855D1 (fi)
DK (1) DK50089A (fi)
FI (1) FI890520A (fi)
HU (1) HU201543B (fi)
IL (1) IL89156A (fi)
NO (1) NO171786C (fi)
NZ (1) NZ227853A (fi)
PT (1) PT89643B (fi)
ZA (1) ZA89905B (fi)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3717561A1 (de) * 1987-05-25 1988-12-08 Thomae Gmbh Dr K Indol-, isochinolin- und benzazepinderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
EP0306375A1 (fr) * 1987-08-07 1989-03-08 Synthelabo Dérivés de[(pipéridinyl-4)méthyl]-2 tétrahydro-1,2,3,4 isoquinoléine, leur préparation et leur application en thérapeutique
FR2661178B1 (fr) * 1990-04-24 1993-03-12 Synthelabo Derives de [(tetrahydro-1,2,3,4 isoquinoleinyl-2)methyl]-4 piperidinecarboxylates-1 d'alkyle, leur preparation et leur application en therapeutique.
US5132311A (en) * 1990-06-27 1992-07-21 G. D. Searle & Co. Cyanoquanidine type III antiarrhythmic agents and use
FR2747386B1 (fr) * 1996-04-12 1998-05-15 Synthelabo Derives de 3-[(1,2,3,4-tetrahydroisoquinolein-2-yl)methyl] -8-azabicyclo [3.2.1] octane, leur preparation et leur application en therapeutique
JP2000517301A (ja) * 1996-08-14 2000-12-26 スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー テトラヒドロイソキノリン誘導体およびそれらの薬理学的使用
GB9708805D0 (en) 1997-05-01 1997-06-25 Smithkline Beecham Plc Compounds
GB9810876D0 (en) 1998-05-20 1998-07-22 Smithkline Beecham Plc Compounds
IL142388A0 (en) 1998-10-08 2002-03-10 Smithkline Beecham Plc Tetrahydrobenzazepine derivatives useful as modulators of dopamine d3 receptors (antipsychotic agents)
DE10060176B4 (de) 2000-12-04 2008-06-19 Precitec Kg Laserbearbeitungskopf
KR101042208B1 (ko) * 2008-09-26 2011-06-20 현대종합금속 주식회사 셀프 쉴디드(ｓｅｌｆ－ｓｈｉｅｌｄｅｄ) 아크 용접 플럭스 충전 와이어
CA2766154C (en) 2009-06-26 2015-04-07 Beverly C. Langevin Novel fumarate salts of a histamine h3 receptor antagonist

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4939677B1 (fi) * 1967-03-14 1974-10-28
FR7607M (fi) * 1968-04-25 1970-01-19
GB1250719A (fi) * 1969-03-19 1971-10-20
US3836536A (en) * 1972-06-08 1974-09-17 Warner Lambert Co 1,2,3,4-tetrahydro-3-aminomethyliso-quinolines
FR2426046A1 (fr) * 1978-05-18 1979-12-14 Synthelabo Derive de tetrahydro-isoquinoleine, sa preparation et son application en therapeutique
US4220778A (en) * 1978-10-30 1980-09-02 G. D. Searle & Co. 8-Aryl-1,2,3,4-tetrahydroisoquinoline and derivatives thereof
US4766131A (en) * 1980-10-17 1988-08-23 Pennwalt Corporation 2-amino (or hydroxy) phenethyl-1,2,3,4-tetrahydroisoquinolines as analgesics
DE3717561A1 (de) * 1987-05-25 1988-12-08 Thomae Gmbh Dr K Indol-, isochinolin- und benzazepinderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
EP0306375A1 (fr) * 1987-08-07 1989-03-08 Synthelabo Dérivés de[(pipéridinyl-4)méthyl]-2 tétrahydro-1,2,3,4 isoquinoléine, leur préparation et leur application en thérapeutique

Also Published As

Publication number Publication date
EP0351255A2 (fr) 1990-01-17
PT89643B (pt) 1994-02-28
ATE95816T1 (de) 1993-10-15
US4925850A (en) 1990-05-15
IL89156A0 (en) 1989-09-10
AU2961789A (en) 1990-01-18
NO890440L (no) 1990-01-15
NO890440D0 (no) 1989-02-03
HUT50327A (en) 1990-01-29
FI890520A0 (fi) 1989-02-03
PT89643A (pt) 1989-10-04
NO171786B (no) 1993-01-25
DK50089D0 (da) 1989-02-03
HU201543B (en) 1990-11-28
IL89156A (en) 1993-05-13
KR900001676A (ko) 1990-02-27
AU606778B2 (en) 1991-02-14
JPH0225481A (ja) 1990-01-26
DE68909855D1 (de) 1993-11-18
FI890520A (fi) 1990-01-13
DK50089A (da) 1990-01-13
NZ227853A (en) 1990-06-26
EP0351255B1 (fr) 1993-10-13
EP0351255A3 (en) 1990-05-02
ZA89905B (en) 1989-10-25

Similar Documents

Publication Publication Date Title
ES2059069T3 (es) Nuevos derivados de 1-alcoxi-(2-acilamino-etil)-naftalenos y su procedimiento de preparacion.
SE8603099L (sv) Distamycinderivat och forfarande for deras framstellning
NO171786C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive isokinolinderivater
ES2037098T3 (es) Procedimiento de preparacion de derivados de la decahidroquinoleina.
DK71780A (da) Fremgangsmaade til fremstilling af difenylhydantoinderivater
ES551274A0 (es) Un procedimiento para la sintesis de derivados de imidazol.
SE8403801D0 (sv) Nya bensotiazepiner med kardiovaskuler anvendbarhet, forfarande for framstellning derav och farmaceutiska kompositioner som innehaller dem
ATE115136T1 (de) 4-phenylphthalazin-derivate.
NO912298L (no) Fremgangsmaate for fremstilling av terapeutisk aktive 1,3-dioksanderivater.
SE8800863L (sv) 3-(2-haloalkyl)-1,4-oxatiiner och 2-(2-haloalkyl)1,4-ditiiner och bahandling av leukemi och tumoerer daermed
DK0461012T3 (da) Derivater af ((1-arylpyrrolidin-2-yl)methyl)piperazin, fremstillingen heraf og deres terapeutiske anvendelse
DK0395527T3 (da) Imidazobenzodiazepiner og deres salte, fremgangsmåde til deres fremstilling, deres anvendelse som lægemidler og præparater med indhold deraf
DK58380A (da) Fremgangsmaade til fremstilling af thiazolderivater
IL97611A (en) Heterocyclic compounds, their preparation and pharmaceutical compositions containing them
SE8701524L (sv) Nya sulfonamider och deras framstaellningsfoerfarande
NO167201C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive semikarbazid-derivater.