NO171367C - Fremgangsmaate for fremstilling av 2',3'-dideoksy-2',3'-didehydronukleosider - Google Patents
Fremgangsmaate for fremstilling av 2',3'-dideoksy-2',3'-didehydronukleosiderInfo
- Publication number
- NO171367C NO171367C NO891208A NO891208A NO171367C NO 171367 C NO171367 C NO 171367C NO 891208 A NO891208 A NO 891208A NO 891208 A NO891208 A NO 891208A NO 171367 C NO171367 C NO 171367C
- Authority
- NO
- Norway
- Prior art keywords
- didehydronucleosides
- dideoxy
- procedure
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/056—Triazole or tetrazole radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NO913456A NO172345C (no) | 1988-03-24 | 1991-09-03 | Fremgangsmaate for fremstilling av 2',3'-dideoksy-2',3'-didehydronukleosider |
| NO913458A NO171315C (no) | 1988-03-24 | 1991-09-03 | Fremgangsmaate for fremstilling av 2',3'-dideoksy-2',3'-didehydronukleosider |
| NO913459A NO171316C (no) | 1988-03-24 | 1991-09-03 | Fremgangsmaate for fremstilling av 2',3'-dideoksy-2',3'-didehydronukleosider r |
| NO913457A NO171314C (no) | 1988-03-24 | 1991-09-03 | Fremgangsmaate for fremstilling av 2',3'-dideoksy-2',3'-didehydronukleosider |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/173,473 US4904770A (en) | 1988-03-24 | 1988-03-24 | Production of 2',3'-dideoxy-2',3'-didehydronucleosides |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| NO891208D0 NO891208D0 (no) | 1989-03-20 |
| NO891208L NO891208L (no) | 1989-09-25 |
| NO171367B NO171367B (no) | 1992-11-23 |
| NO171367C true NO171367C (no) | 1993-03-03 |
Family
ID=22632190
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO891208A NO171367C (no) | 1988-03-24 | 1989-03-20 | Fremgangsmaate for fremstilling av 2',3'-dideoksy-2',3'-didehydronukleosider |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US4904770A (fi) |
| EP (1) | EP0334368A3 (fi) |
| JP (1) | JPH02149595A (fi) |
| KR (2) | KR0140889B1 (fi) |
| AU (1) | AU622439B2 (fi) |
| CA (1) | CA1339448C (fi) |
| DK (1) | DK146489A (fi) |
| EG (1) | EG18661A (fi) |
| FI (1) | FI93111C (fi) |
| IL (2) | IL89693A (fi) |
| NO (1) | NO171367C (fi) |
| NZ (1) | NZ228390A (fi) |
| PT (1) | PT90099B (fi) |
| ZA (1) | ZA892166B (fi) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5455339A (en) * | 1986-05-01 | 1995-10-03 | University Of Georgia Research Foundation, Inc. | Method for the preparation of 2',3'-dideoxy and 2',3'-dideoxydide-hydro nucleosides |
| US5384396A (en) * | 1988-02-23 | 1995-01-24 | The University Of Georgia Research Foundation, Inc. | Process for the deoxygenation of nucleosides |
| JPH02152976A (ja) * | 1988-05-06 | 1990-06-12 | Bristol Myers Co | ２´，３´―ジデヒドロ―２´，３´―ジデオキシヌクレオシドのプロドラッグ |
| SE464168B (sv) * | 1989-07-19 | 1991-03-18 | Bo Fredrik Oeberg | Antiviral komposition bestaaende av en 3'-fluoro-2',3'-dideoxynukleosidfoerening och en 2',3'-dideoxynukleosidfoerening (exempelvis azt) |
| US5200514A (en) * | 1990-01-19 | 1993-04-06 | University Of Georgia Research Foundation, Inc. | Synthesis of 2'-deoxypyrimidine nucleosides |
| EP0493602A4 (en) * | 1990-07-27 | 1993-01-20 | Yuki Gosei Kogyo Co., Ltd. | Process for producing 2',3'-dideoxy-2',3'-didehydronucleoside |
| US5166327A (en) * | 1990-07-31 | 1992-11-24 | Yuki Gosei Kogyo Co., Ltd. | Process for producing 3'-deoxy-3-'-fluorothymidine |
| JP3042073B2 (ja) * | 1991-06-19 | 2000-05-15 | 味の素株式会社 | ヌクレオシド誘導体とその製造方法 |
| DE550714T1 (de) * | 1991-06-21 | 1995-06-14 | Acic Canada Inc | Antiviralverbindungen und Ihrer Verfahren zur Herstellung. |
| FR2688003B1 (fr) * | 1992-02-28 | 1995-06-30 | Univ Limoges | Derives de nucleosides, leur preparation et leurs applications biologiques. |
| US5506349A (en) * | 1992-05-13 | 1996-04-09 | Ribozyme Pharmaceuticals, Inc. | Chemical synthesis of 2', 3'-dideoxycytidine |
| US5539099A (en) * | 1993-11-15 | 1996-07-23 | Bristol-Myers Squibb Company | Process for large-scale preparation of 2',3'-didehydro-2',3'-dideoxynucleosides |
| US5608049A (en) * | 1995-03-10 | 1997-03-04 | Bristol-Myers Squibb Company | Preparation of d4T from 5-methyluridine |
| US5608048A (en) * | 1995-06-05 | 1997-03-04 | Bristol-Myers Squibb Company | d4 T polymorphic Form 1 process |
| US6635753B1 (en) | 1998-09-30 | 2003-10-21 | Brantford Chemicals Inc. | Process for the preparation of substantially pure stavudine and related intermediates useful in the preparation thereof |
| US7638496B2 (en) | 2000-02-15 | 2009-12-29 | Valeant Pharmaceuticals North America | Nucleoside analogs with carboxamidine modified monocyclic base |
| IT1318463B1 (it) * | 2000-04-12 | 2003-08-25 | Archimica S P A Ora Clariant L | Procedimento per la preparazione di 5'-acetilstavudina. |
| CN1505635A (zh) | 2001-03-01 | 2004-06-16 | 2′,3′-二脱氧-2＇,3＇-二脱氢核苷的合成方法 | |
| US20050131224A1 (en) * | 2003-12-15 | 2005-06-16 | Cti Pet Systems, Inc. | Method for preparing radiolabeled thymidine |
| US7160537B2 (en) * | 2003-12-15 | 2007-01-09 | Siemens Medical Solutions Usa, Inc. | Method for preparing radiolabeled thymidine having low chromophoric byproducts |
| US20050171126A1 (en) * | 2003-12-26 | 2005-08-04 | Ajinomoto Co., Inc. | Process for the production of purine nucleoside compounds |
| US7250416B2 (en) | 2005-03-11 | 2007-07-31 | Supergen, Inc. | Azacytosine analogs and derivatives |
| US20090148407A1 (en) | 2005-07-25 | 2009-06-11 | Intermune, Inc. | Novel Macrocyclic Inhibitors of Hepatitis C Virus Replication |
| US7700567B2 (en) | 2005-09-29 | 2010-04-20 | Supergen, Inc. | Oligonucleotide analogues incorporating 5-aza-cytosine therein |
| CN101029068B (zh) * | 2007-04-09 | 2010-06-23 | 陆咏 | 一种2',3'-二脱氢-3'-脱氧胸苷的合成方法 |
| LT2750768T (lt) | 2011-08-30 | 2019-02-11 | Astex Pharmaceuticals, Inc. | Decitabino darinio kompozicijos |
| US20160060252A1 (en) * | 2013-04-16 | 2016-03-03 | Bristol-Myers Squibb Company | 5-methyluridine method for producing festinavir |
| AU2016287585B2 (en) | 2015-07-02 | 2020-12-17 | Otsuka Pharmaceutical Co., Ltd. | Lyophilized pharmaceutical compositions |
| MX2020001233A (es) | 2017-08-03 | 2020-07-20 | Otsuka Pharma Co Ltd | Compuesto farmaceutico y metodos de purificacion del mismo. |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3322747A (en) * | 1965-04-01 | 1967-05-30 | Merck & Co Inc | Thionocarbonate nucleosides |
| US3539550A (en) * | 1967-01-23 | 1970-11-10 | Syntex Corp | Process for the preparation of 2'-halo-2'-deoxy pyrimidine nucleosides |
| US3792040A (en) * | 1970-03-19 | 1974-02-12 | Syntex Corp | Acyl derivatives of o2,2'-anhydro-1-(beta-d-arabinofuranosyl)-cytosines and methods of preparing |
-
1988
- 1988-03-24 US US07/173,473 patent/US4904770A/en not_active Expired - Lifetime
-
1989
- 1989-03-15 CA CA000593738A patent/CA1339448C/en not_active Expired - Fee Related
- 1989-03-20 NZ NZ228390A patent/NZ228390A/en unknown
- 1989-03-20 NO NO891208A patent/NO171367C/no unknown
- 1989-03-21 IL IL8969389A patent/IL89693A/en not_active IP Right Cessation
- 1989-03-21 FI FI891338A patent/FI93111C/fi not_active IP Right Cessation
- 1989-03-21 IL IL10557389A patent/IL105573A/en not_active IP Right Cessation
- 1989-03-22 DK DK146489A patent/DK146489A/da not_active Application Discontinuation
- 1989-03-22 ZA ZA892166A patent/ZA892166B/xx unknown
- 1989-03-23 EG EG144/89A patent/EG18661A/xx active
- 1989-03-23 JP JP1071592A patent/JPH02149595A/ja active Pending
- 1989-03-23 PT PT90099A patent/PT90099B/pt not_active IP Right Cessation
- 1989-03-23 AU AU31673/89A patent/AU622439B2/en not_active Ceased
- 1989-03-23 KR KR89003629A patent/KR0140889B1/ko not_active IP Right Cessation
- 1989-03-23 EP EP19890105269 patent/EP0334368A3/en not_active Ceased
-
1997
- 1997-10-23 KR KR97054314A patent/KR0142109B1/ko not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| FI891338A0 (fi) | 1989-03-21 |
| IL105573A (en) | 1994-04-12 |
| CA1339448C (en) | 1997-09-09 |
| FI93111C (fi) | 1995-02-27 |
| IL89693A0 (en) | 1989-09-28 |
| DK146489D0 (da) | 1989-03-22 |
| FI93111B (fi) | 1994-11-15 |
| EP0334368A2 (en) | 1989-09-27 |
| IL89693A (en) | 1994-08-26 |
| NO171367B (no) | 1992-11-23 |
| NO891208D0 (no) | 1989-03-20 |
| KR0140889B1 (en) | 1998-06-15 |
| EG18661A (en) | 1993-10-30 |
| NO891208L (no) | 1989-09-25 |
| FI891338A (fi) | 1989-09-25 |
| AU3167389A (en) | 1989-09-28 |
| EP0334368A3 (en) | 1991-12-27 |
| KR0142109B1 (en) | 1998-07-01 |
| ZA892166B (en) | 1992-02-26 |
| NZ228390A (en) | 1991-12-23 |
| PT90099A (pt) | 1989-11-10 |
| AU622439B2 (en) | 1992-04-09 |
| KR890014528A (ko) | 1989-10-24 |
| US4904770A (en) | 1990-02-27 |
| DK146489A (da) | 1989-09-25 |
| JPH02149595A (ja) | 1990-06-08 |
| PT90099B (pt) | 1994-07-29 |
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