NO168041B - ANALOGY PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE RETINIC ACID ESTERS OF ERYTROMYCIN. - Google Patents
ANALOGY PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE RETINIC ACID ESTERS OF ERYTROMYCIN. Download PDFInfo
- Publication number
- NO168041B NO168041B NO871870A NO871870A NO168041B NO 168041 B NO168041 B NO 168041B NO 871870 A NO871870 A NO 871870A NO 871870 A NO871870 A NO 871870A NO 168041 B NO168041 B NO 168041B
- Authority
- NO
- Norway
- Prior art keywords
- lid
- erytromycin
- preparation
- acid esters
- therapeutic active
- Prior art date
Links
- 239000002253 acid Substances 0.000 title 1
- 230000001225 therapeutic effect Effects 0.000 title 1
- 238000005192 partition Methods 0.000 claims description 11
- 230000035515 penetration Effects 0.000 claims description 3
- 238000005304 joining Methods 0.000 claims description 2
- 238000003466 welding Methods 0.000 description 6
- 239000003792 electrolyte Substances 0.000 description 2
- 230000037431 insertion Effects 0.000 description 2
- 238000003780 insertion Methods 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 238000004026 adhesive bonding Methods 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 238000005476 soldering Methods 0.000 description 1
- 239000007858 starting material Substances 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/671—Vitamin A; Derivatives thereof, e.g. ester of vitamin A acid, ester of retinol, retinol, retinal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/02—Acyclic radicals, not substituted by cyclic structures
- C07H15/14—Acyclic radicals, not substituted by cyclic structures attached to a sulfur, selenium or tellurium atom of a saccharide radical
- C07H15/16—Lincomycin; Derivatives thereof
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Dermatology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Oncology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Communicable Diseases (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Cosmetics (AREA)
Description
Flercellet akkumulatorbatteri. Multi-cell accumulator battery.
Foreliggende oppfinnelse angår akkumulatorbatterier The present invention relates to accumulator batteries
av den type hvor flere celler er anordnet i en beholder, såkalte monoblokkbatterier. Et eksempel på slike batterier er startbatte-rier for biler. of the type where several cells are arranged in a container, so-called monobloc batteries. An example of such batteries are starter batteries for cars.
Oppfinnelsen angår nærmere bestemt den type av monoblokkbatterier hvor elektriske forbindelser mellom ved siden av hverandre liggende celler er anordnet som gjennomføringer i skilleveggen mellom dem. The invention specifically relates to the type of monobloc batteries where electrical connections between adjacent cells are arranged as penetrations in the partition between them.
Batteriet ifolge oppfinnelsen består av flere ved siden av hverandre i samme beholder anordnede, fortrinnsvis med felles lokk tildekkede celler som skilles fra hverandre ved isolerende væsketette vegger, hvori er anordnet elektrisk ledende forbindelser, så som gjennomføring fra en celle til en inntil liggende celle, og oppfinnelsen utmerker seg ved at skilleveggdeler omfat- The battery according to the invention consists of several cells arranged next to each other in the same container, preferably covered with a common lid, which are separated from each other by insulating liquid-tight walls, in which electrically conductive connections are arranged, such as a passage from one cell to an adjacent cell, and the invention is distinguished by the fact that partition parts include
tende nevnte gjennomføringer er anordnet i lokket. Tend said penetrations are arranged in the lid.
Det er ut fra flere synspunkter fordelaktig å fore de elektrisk ledende organer som forbinder elektrodesett i inntil hverandre anbrakte celler med hverandre, gjennom skilleveggen mellom nevnte celler. Det oppnås, som det lett vil innsees, be-tydelige materialbesparelser sammenlignet med den hittil vanlig brukte anordning av nevnte forbindelser utenpå batterilokkene. From several points of view, it is advantageous to line the electrically conductive bodies which connect electrode sets in adjacent cells to each other, through the partition between said cells. Significant material savings are achieved, as will be easily seen, compared to the previously commonly used arrangement of said connections on the outside of the battery lids.
En annen fordel består i at batteriet får en glatt over-side som med unntagelse av tilkoblingspolene savner ytre elektrisk ledende metalldeler. Another advantage is that the battery has a smooth upper side which, with the exception of the connection poles, lacks external electrically conductive metal parts.
Flere konstruksjoner er kjent, hvor ovennevnte fordeler er oppnådd på den angitte måte, imidlertid har det derved vist seg at for eller senere er der oppstått lekkasjer og.manglende tetthet for den i cellene foreliggende elektrolyt ved festepunktene for de nevnte elektrisk ledende gjennomforinger. Several constructions are known, where the above-mentioned advantages are achieved in the manner indicated, however, it has thereby been shown that sooner or later there have been leaks and a lack of tightness for the electrolyte present in the cells at the attachment points for the aforementioned electrically conductive bushings.
Vanskelighetene har sin årsak i at de ledende forbindelser fra en celle til den tilliggende celle må anbringes etter at cellens elektroder og separatorer er kommet på plass. Ved sam-mensetningen av akkumulatorer legges negative og positive elektroder sammen og loddes til sine respektive polbroer for innset-ning i cellebeholderne. Elektrodene skilles ved hjelp av elektrisk isolerende gjennomtrengelige separatorer eller skillevegger. Elektroder med samme polaritet loddes ved spesielle tilkoblingspunkter til såkalte polbroer og danner såkalte platesett. Platesettene The reason for the difficulties lies in the fact that the conductive connections from one cell to the adjacent cell must be placed after the cell's electrodes and separators have been put in place. During the assembly of accumulators, negative and positive electrodes are put together and soldered to their respective pole bridges for insertion in the cell containers. The electrodes are separated by means of electrically insulating permeable separators or partitions. Electrodes with the same polarity are soldered at special connection points to so-called pole bridges and form so-called plate sets. The plate sets
fyller ut cellene fullstendig for at elektrodene skal stå stott fills the cells completely so that the electrodes will stand
og ikke skades ved vibrasjoner og lignende. Dette innebærer imidlertid at i skilleveggene mellom cellene må der ikke være anbrakt noen gjennomforingsanordninger for platesettene er innfort i cellene. and not be damaged by vibrations and the like. This means, however, that in the partitions between the cells there must not be any feed-through devices for the plate sets to be inserted into the cells.
Ved hjelp av oppfinnelsen overvinnes disse og andre van-skeligheter som foreligger ved fremstillingen av akkumulatorer av angjeldende type på en effektiv og enkel måte ved at gjennomfbrin-gene er anordnet i de skilleveggpartier som er anordnet i behol-derlokkene. With the help of the invention, these and other difficulties which exist in the production of accumulators of the type in question are overcome in an efficient and simple way by the through-holes being arranged in the partition sections which are arranged in the container lids.
Oppfinnelsen skal i det folgende beskrives nærmere under henvisning til tegningene, hvor fig. 1 viser et akkumulatorbatteri i likhet med oppfinnelsen i delvis lengdesnitt, fig. 2 viser et delvis tverrsnitt, fig. 3 er et planriss ai samme og fig. 4 er et perspektivisk oppriss av et akkumulatorbatteri i samsvar med oppfinnelsen med en for illustrasjon avtatt dekkplate. The invention will be described in more detail below with reference to the drawings, where fig. 1 shows an accumulator battery similar to the invention in partial longitudinal section, fig. 2 shows a partial cross-section, fig. 3 is a plan view of the same and fig. 4 is a perspective elevation of an accumulator battery in accordance with the invention with a cover plate removed for illustration.
Akkumulatorbatteriet består av beholderen 1 som er delt opp i flere celler ved hjelp av skilleveggene 2 og tilhørende lokk 3. Skilleveggene 4,.er anbrakt i lokket 3 i samsvar med skilleveggene 2 i beholderen 1. Elektrisk ledende gjennomforinger 5 er væsketett f byd inn i mellom veggene 4 i lokket 3, fortrinnsvis på en slik måte at ved fremstillingen av lokket blir gjennomforingene stopt eller presset inn og anbringes i presse- henholdsvis stope-formen for lokket. Elektroder med en bestemt polaritet er for inn-setningen i beholderen 1 fortrinnsvis ved lodding, forbundet med polbroen 7. Polbroene 7 forbindes med gjennomfbringen 5 etter at lokket 3 er kommet på plass på beholderen. Forbindelsen skjer for eksempel ved motstandssveising gjennom åpningene 8 i lokket 3, hvilke åpninger deretter lukkes ved hjelp av dekkplater 9. Separatorer eller skillevegger 10 holder elektrodene 11 og 6 isolert fra hverandre* Tilkoblingspolene 12 og 13 muliggjør tilkobling til en ytre strbmkrets, en tetningsanordning 14 dekker inspeksjons- og påfyllingsåpningene 15 for påfylling av elektrolyt. Sammensetning av lokk og beholder ved 16 skjer fortrinnsvis ved hjelp av såkalt speilsveising, men kan selvfølgelig også skje ved hjelp av klebing eller sveising ved hjelp av for eksempel varme tråd. Sammenføynin-gen av polbroene 7 med gjennomfbringen 5 i forbindelsesstedene 17 skjer fortrinnsvis ved hjelp av elektrisk motstandssveising ved hjelp av hertil egnet utformede sveisetenger eller lignende gjennom åpningene 8. Dekkplatene 9 festes på plass etter at sveisingen' av polbroene 7 til gjennomfbringen 5 er utfort. The storage battery consists of the container 1, which is divided into several cells by means of the partitions 2 and associated lid 3. The partitions 4, are placed in the lid 3 in accordance with the partitions 2 in the container 1. Electrically conductive bushings 5 are liquid-tight f bid into between the walls 4 of the lid 3, preferably in such a way that during the production of the lid, the bushings are stopped or pressed in and placed in the press or stope form for the lid. Electrodes with a certain polarity are, for the insertion in the container 1, preferably by soldering, connected to the pole bridge 7. The pole bridges 7 are connected to the through-hole 5 after the lid 3 has been placed on the container. The connection takes place, for example, by resistance welding through the openings 8 in the lid 3, which openings are then closed using cover plates 9. Separators or partitions 10 keep the electrodes 11 and 6 isolated from each other* The connection poles 12 and 13 enable connection to an external power circuit, a sealing device 14 covers the inspection and filling openings 15 for filling with electrolyte. Assembly of lid and container at 16 is preferably done using so-called mirror welding, but can of course also be done using gluing or welding using, for example, hot wire. The joining of the pole bridges 7 with the lead-through 5 in the connection points 17 preferably takes place by means of electric resistance welding with the help of suitably designed welding tongs or the like through the openings 8. The cover plates 9 are fixed in place after the welding of the pole bridges 7 to the lead-through 5 has been carried out.
Ovenstående beskrivelse og vedlagte tegninger gjelder for et rent utfort eksempel på oppfinnelsen og må ikke ansees som begrensende av samme.. The above description and attached drawings apply to a purely developed example of the invention and must not be regarded as limiting the same.
Claims (2)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NO910442A NO168647C (en) | 1986-05-06 | 1991-02-05 | ANALOGY PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE RETINIC ACID ESTERS OF LINCOMYCIN AND CLINDAMYCIN. |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR8606528A FR2598420B1 (en) | 1986-05-06 | 1986-05-06 | NOVEL RETINOIC ANTIBIOTICS ESTERS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING THEM |
Publications (4)
Publication Number | Publication Date |
---|---|
NO871870D0 NO871870D0 (en) | 1987-05-05 |
NO871870L NO871870L (en) | 1987-11-09 |
NO168041B true NO168041B (en) | 1991-09-30 |
NO168041C NO168041C (en) | 1992-01-08 |
Family
ID=9334966
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO871870A NO168041C (en) | 1986-05-06 | 1987-05-05 | ANALOGY PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE RETINIC ACID ESTERS OF ERYTROMYCIN. |
Country Status (13)
Country | Link |
---|---|
JP (1) | JP2504990B2 (en) |
BE (1) | BE1004152A4 (en) |
CA (1) | CA1300131C (en) |
CH (1) | CH674847A5 (en) |
DE (1) | DE3714937C2 (en) |
DK (1) | DK169345B1 (en) |
ES (1) | ES2006478A6 (en) |
FR (1) | FR2598420B1 (en) |
GB (1) | GB2191483B (en) |
IT (1) | IT1204556B (en) |
NL (1) | NL193946C (en) |
NO (1) | NO168041C (en) |
SE (1) | SE470379B (en) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
LU87041A1 (en) * | 1987-11-04 | 1989-06-14 | Oreal | RETINOIC ESTERS OF MACROLIDES, THEIR PREPARATION PROCESS AND PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING THEM |
LU87037A1 (en) * | 1987-11-04 | 1989-06-14 | Oreal | POLYAROMATIC ESTERS OF MACROLIDIC AND LINCOSAMIDIC ANTIBIOTICS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING THEM |
LU87035A1 (en) * | 1987-11-04 | 1989-06-14 | Oreal | ETRETINIC OR APPARENT TYPE ESTERS OF MACROLIDIC AND LINCOSAMIDIC ANTIBIOTICS, PREPARATION METHOD THEREOF, AND PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING THEM |
LU87038A1 (en) * | 1987-11-04 | 1989-06-14 | Oreal | AROMATIC ESTERS OF MACROLIDIC AND LINCOSAMIDIC ANTIBIOTICS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING THEM |
LU87036A1 (en) * | 1987-11-04 | 1989-06-14 | Oreal | UNSATURATED CYCLOALIPHATIC ESTERS OF MACROLIDIC AND LINCOSAMIDIC ANTIBIOTICS, PREPARATION METHOD THEREOF, AND PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING THEM |
LU87040A1 (en) * | 1987-11-04 | 1989-06-14 | Oreal | POLYCYCLIC AROMATIC ESTERS OF MACROLIDIC AND LINCOSAMIDIC ANTIBIOTICS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING THEM |
LU87039A1 (en) * | 1987-11-04 | 1989-06-14 | Oreal | BIAROMATIC ESTERS OF MACROLIDIC AND LINCOSAMIDIC ANTIBIOTICS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING THEM |
LU87070A1 (en) * | 1987-12-10 | 1989-07-07 | Oreal | COMBINATION OF PYRIMIDINE DERIVATIVES AND AGENTS FOR INDUCING AND STIMULATING HAIR GROWTH AND REDUCING FALLING |
FR2644460A1 (en) * | 1989-03-16 | 1990-09-21 | Oreal | RETINOIC ESTERS OF D-DESOSAMINE, PROCESS FOR THEIR PREPARATION AND THEIR USE IN HUMAN OR VETERINARY MEDICINE AND IN COSMETICS |
GB2282596B (en) * | 1993-10-06 | 1998-04-15 | Ciba Geigy Ag | Water-soluble retinoids |
FR2931662B1 (en) * | 2008-05-30 | 2010-07-30 | Galderma Res & Dev | NOVEL DEPIGMENTING COMPOSITIONS IN THE FORM OF AN ANHYDROUS VASELIN - FREE AND ELASTOMER - FREE COMPOSITION COMPRISING A SOLUBILIZED PHENOLIC DERIVATIVE. |
FR2931661B1 (en) * | 2008-05-30 | 2010-07-30 | Galderma Res & Dev | NOVEL DEPIGMENTING COMPOSITIONS IN THE FORM OF AN ANHYDROUS VASELIN - FREE AND ELASTOMER - FREE COMPOSITION COMPRISING A SOLUBILIZED PHENOLIC DERIVATIVE AND A RETINOID. |
US9907812B2 (en) * | 2011-06-22 | 2018-03-06 | Vyome Biosciences Pvt. Ltd. | Conjugate-based antifungal and antibacterial prodrugs |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2862921A (en) * | 1953-08-13 | 1958-12-02 | Upjohn Co | Erythromycin esters |
US3598806A (en) * | 1969-04-15 | 1971-08-10 | Upjohn Co | Process for preparing lincomycin-3-monoacylates |
FR2378523A1 (en) * | 1977-01-26 | 1978-08-25 | Grupper Charles | ACNE TREATMENT MEDICINE |
FR2582000B1 (en) * | 1985-05-14 | 1987-06-26 | Oreal | BI OR TRI-ENIC FATTY ESTERS OF ERYTHROMYCIN A, THEIR PREPARATION PROCESS AND PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING THEM |
-
1986
- 1986-05-06 FR FR8606528A patent/FR2598420B1/en not_active Expired - Lifetime
-
1987
- 1987-05-02 JP JP62107980A patent/JP2504990B2/en not_active Expired - Lifetime
- 1987-05-04 NL NL8701054A patent/NL193946C/en not_active IP Right Cessation
- 1987-05-05 DE DE3714937A patent/DE3714937C2/en not_active Expired - Lifetime
- 1987-05-05 NO NO871870A patent/NO168041C/en unknown
- 1987-05-05 DK DK229387A patent/DK169345B1/en not_active IP Right Cessation
- 1987-05-05 CA CA000536348A patent/CA1300131C/en not_active Expired - Lifetime
- 1987-05-05 IT IT20389/87A patent/IT1204556B/en active
- 1987-05-05 CH CH1705/87A patent/CH674847A5/fr not_active IP Right Cessation
- 1987-05-05 SE SE8701845A patent/SE470379B/en not_active IP Right Cessation
- 1987-05-05 ES ES8701603A patent/ES2006478A6/en not_active Expired
- 1987-05-06 GB GB8710673A patent/GB2191483B/en not_active Expired - Lifetime
- 1987-05-06 BE BE8700486A patent/BE1004152A4/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
DK169345B1 (en) | 1994-10-10 |
NL193946C (en) | 2001-03-02 |
BE1004152A4 (en) | 1992-10-06 |
DE3714937A1 (en) | 1987-11-12 |
JP2504990B2 (en) | 1996-06-05 |
NL8701054A (en) | 1987-12-01 |
JPS62289593A (en) | 1987-12-16 |
FR2598420A1 (en) | 1987-11-13 |
DK229387A (en) | 1987-11-07 |
ES2006478A6 (en) | 1989-05-01 |
NO871870D0 (en) | 1987-05-05 |
DE3714937C2 (en) | 1998-02-26 |
GB2191483B (en) | 1990-05-30 |
SE470379B (en) | 1994-02-07 |
IT1204556B (en) | 1989-03-10 |
NO871870L (en) | 1987-11-09 |
NL193946B (en) | 2000-11-01 |
GB8710673D0 (en) | 1987-06-10 |
SE8701845D0 (en) | 1987-05-05 |
IT8720389A0 (en) | 1987-05-05 |
SE8701845L (en) | 1987-11-07 |
CA1300131C (en) | 1992-05-05 |
GB2191483A (en) | 1987-12-16 |
NO168041C (en) | 1992-01-08 |
CH674847A5 (en) | 1990-07-31 |
DK229387D0 (en) | 1987-05-05 |
FR2598420B1 (en) | 1991-06-07 |
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