NO166943C - Analogifremgangsmaate for fremstilling av enzymresistente immunomodulerende peptider. - Google Patents

Analogifremgangsmaate for fremstilling av enzymresistente immunomodulerende peptider.

Info

Publication number
NO166943C
NO166943C NO844579A NO844579A NO166943C NO 166943 C NO166943 C NO 166943C NO 844579 A NO844579 A NO 844579A NO 844579 A NO844579 A NO 844579A NO 166943 C NO166943 C NO 166943C
Authority
NO
Norway
Prior art keywords
enzymesresistent
preparing
analogy procedure
modulating peptides
peptides
Prior art date
Application number
NO844579A
Other languages
English (en)
Norwegian (no)
Other versions
NO166943B (no
NO844579L (no
Inventor
Gideon Goldstein
George Heavner
Daniel Kroon
Tapan Audhya
Original Assignee
Ortho Pharma Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho Pharma Corp filed Critical Ortho Pharma Corp
Publication of NO844579L publication Critical patent/NO844579L/no
Publication of NO166943B publication Critical patent/NO166943B/no
Publication of NO166943C publication Critical patent/NO166943C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/66—Thymopoietins
    • C07K14/662—Thymopoietins at least 1 amino acid in D-form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/66—Thymopoietins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/18—Thymus derived hormone or factor; related peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Endocrinology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Vibration Dampers (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
NO844579A 1983-11-18 1984-11-16 Analogifremgangsmaate for fremstilling av enzymresistente immunomodulerende peptider. NO166943C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/553,281 US4505853A (en) 1983-11-18 1983-11-18 Enzyme-resistant immunomodulatory peptides

Publications (3)

Publication Number Publication Date
NO844579L NO844579L (no) 1985-05-20
NO166943B NO166943B (no) 1991-06-10
NO166943C true NO166943C (no) 1991-09-18

Family

ID=24208835

Family Applications (1)

Application Number Title Priority Date Filing Date
NO844579A NO166943C (no) 1983-11-18 1984-11-16 Analogifremgangsmaate for fremstilling av enzymresistente immunomodulerende peptider.

Country Status (14)

Country Link
US (1) US4505853A (fr)
EP (1) EP0146266B1 (fr)
JP (2) JPH0753752B2 (fr)
KR (1) KR940001007B1 (fr)
AT (1) ATE63748T1 (fr)
AU (1) AU579595B2 (fr)
CA (1) CA1269498A (fr)
DE (1) DE3484616D1 (fr)
DK (1) DK167928B1 (fr)
FI (1) FI86860C (fr)
IL (1) IL73533A (fr)
NO (1) NO166943C (fr)
NZ (1) NZ210194A (fr)
ZA (1) ZA848973B (fr)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3401545A1 (de) * 1983-08-03 1985-02-14 Hoechst Ag, 6230 Frankfurt Neue peptide mit immunstimulierender wirkung, verfahren zu deren herstellung und deren verwendung
US4629723A (en) * 1984-06-27 1986-12-16 Ortho Pharmaceutical Corporation Potent thymopentin analogs
WO1986004334A1 (fr) * 1985-01-18 1986-07-31 MERCK Patent Gesellschaft mit beschränkter Haftung Peptides de regulation immunitaire
DE3619633A1 (de) * 1986-06-11 1987-12-17 Hoechst Ag Peptide mit einfluss auf die diurese und natriurese, verfahren zu ihrer herstellung, diese enthaltende mittel und ihre verwendung
US5200506A (en) * 1987-03-19 1993-04-06 Eniricerche S.P.A. Process for preparing new thymopentin retro-inverso analogs and fragments thereof and the intermediates obtained therein
IT1216908B (it) * 1987-03-19 1990-03-14 Eniricerche Spa Analoghi retro-inversi della timopentina e dei suoi frammenti, il metodo per la loro sintesi ed il loro impiego per la preparazionedi composizioni farmaceutiche.
US5656601A (en) * 1987-06-19 1997-08-12 Berlin-Chemie Ag Acylated splenopentins, methods for their synthesis and their use
JPH01125328A (ja) * 1987-07-30 1989-05-17 Centro Natl De Biopreparados 髄膜炎菌ワクチン
US5807830A (en) * 1987-12-30 1998-09-15 Cytoven J.V. Method for treatment of purulent inflammatory diseases
US5728680A (en) 1987-12-30 1998-03-17 Cytoven J.V. Methods for normalizing numbers of lymphocytes
GB8807427D0 (en) * 1988-03-28 1988-05-05 National Biological Standards Board Peptides
WO1989009229A1 (fr) * 1988-03-31 1989-10-05 Immunobiology Research Institute, Inc. Traitement de patient atteint de viremie du hiv a l'aide de thymopentine
NZ229004A (en) * 1988-05-19 1993-09-27 Immunobiology Res Inst Inc Tetrapeptides having t cell helper acitivity
HU201095B (en) * 1988-06-14 1990-09-28 Richter Gedeon Vegyeszet New peptides inhibiting the activity of the immune system and pharmaceutical compositions comprising same, as well as process for producing these peptides and compositions
US5225400A (en) * 1988-07-29 1993-07-06 Ellem Industria Farmaceutica S.R.L. Immunostimulating peptides, a process for their preparation and pharmaceutical compositions containing them
IT1226552B (it) * 1988-07-29 1991-01-24 Ellem Ind Farmaceutica Peptidi immunostimolanti.
KR900701298A (ko) * 1988-09-30 1990-12-01 원본미기재 T-세포 억제작용을 보유한 펩티드
DE3833936C1 (fr) * 1988-10-05 1989-09-21 Henning Berlin Gmbh Chemie- Und Pharmawerk, 1000 Berlin, De
US5811399A (en) * 1988-12-14 1998-09-22 Cytran, Inc. Pharmaceutical dipeptide compositions and methods of use thereof: immunodepressants
IT1227908B (it) * 1988-12-23 1991-05-14 Eniricerche S P A Milano Sclav Nuovi analoghi retro-inversi della timopentina, il metodo per la loro sintesi ed il loro impiego per la preparazione di composizioni farmaceutiche
US5218089A (en) * 1988-12-23 1993-06-08 Sclavo S.P.A. Retro-inverso analogues of thymopentin and the method for their synthesis
US5036050A (en) * 1989-01-12 1991-07-30 Immunobiology Research Institute, Inc. Compositions containing thymopentin for topical treatment of skin disorders
US5770576A (en) * 1989-08-30 1998-06-23 Cytran, Inc. Pharmaceutical dipeptide compositions and methods of use thereof: systemic toxicity
JP2745351B2 (ja) * 1991-02-14 1998-04-28 富士写真フイルム株式会社 ペプチド誘導体及びその用途
WO1992019254A1 (fr) * 1991-04-24 1992-11-12 Warner-Lambert Company POLYPEPTIDES α SUBSTITUES AYANT DES PROPRIETES THERAPEUTIQUES
DK53291D0 (da) * 1991-03-25 1991-03-25 Carlbiotech Ltd As Smaa peptider og peptidrelaterede stoffer samt farmaceutiske praeparater indeholdende saadanne forbindelser
US5215964A (en) * 1991-06-03 1993-06-01 Immunobiology Research Institute, Inc. Peptides useful in regulating the immune and nervous systems
US6066622A (en) * 1991-10-28 2000-05-23 Cytran, Inc. Immunomodulating peptides and methods of use
US6100380A (en) * 1991-10-28 2000-08-08 Cytran, Inc. Immunomodulating peptides and methods of use
WO1994025482A1 (fr) * 1993-04-23 1994-11-10 Evans Herbert J Polypeptides comprenant des groupes contraignant la conformation qui sont adjacents a un site d'interaction proteine-proteine
US5952465A (en) * 1993-04-23 1999-09-14 Virginia Commonwealth University Polypeptides that include conformation-constraining groups which flank a protein-protein interaction site
US5928896A (en) * 1993-04-23 1999-07-27 Virginia Commonwealth University Polypeptides that include conformation-constraining groups which flank a protein--protein interaction site
US6258550B1 (en) 1993-04-23 2001-07-10 Virginia Commonwealth University Polypeptides that include conformation-constraining groups which flank a protein-protein interaction site
US5965698A (en) * 1993-04-23 1999-10-12 Virginia Commonwealth University Polypeptides that include conformation-constraining groups which flank a protein--protein interaction site
US5639729A (en) * 1993-08-26 1997-06-17 Immunobiology Research Institute, Inc. Tripeptides useful in immune and CNS therapy
US6084066A (en) * 1993-10-29 2000-07-04 Virginia Commonwealth University Polypetides that include conformation-constraining groups which flank a protein-protein interaction site
US6849712B1 (en) * 1998-01-22 2005-02-01 Regents Of The University Of Minnesota Peptides with β1 integrin subunit dependent cell adhesion modulating activity
CN1927879B (zh) * 2006-09-25 2010-11-24 吉林大学 胸腺五肽活性异构体及其在药物制备中的应用
CN101168560B (zh) * 2006-10-23 2012-09-05 江苏正大天晴药业股份有限公司 N-取代肽酰胺，其药物组合物与用途

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4077949A (en) 1973-12-28 1978-03-07 Sloan-Kettering Institute For Cancer Research Polypeptide hormones of the thymus
US4002740A (en) 1975-08-21 1977-01-11 Gideon Goldstein Tridecapeptide compositions and methods
US4190646A (en) * 1975-11-11 1980-02-26 Sloan-Kettering Institute For Cancer Research Polypeptide compositions and methods
CA1157466A (fr) * 1979-04-12 1983-11-22 Gideon Goldstein Peptides ayant des proprietes ressemblant a celles de la thymopoietine
US4261886A (en) * 1980-03-13 1981-04-14 Ortho Pharmaceutical Corporation Peptides having thymopoietin-like activity
ZA802170B (en) * 1979-04-12 1981-11-25 Ortho Pharma Corp Peptides having thymopoietin-like activity
DE2938420A1 (de) * 1979-09-22 1981-04-09 Hoechst Ag, 6000 Frankfurt Neue peptide und verfahren zu ihrer herstellung
US4309340A (en) * 1980-03-31 1982-01-05 American Home Products Corporation Polypeptide compositions
US4369137A (en) * 1980-06-17 1983-01-18 Ortho Pharmaceutical Corporation N-Protected pentapeptides useful as intermediates in the preparation of thymopoietin pentapeptide
US4298523A (en) * 1980-06-17 1981-11-03 Ortho Pharmaceutical Corporation Methods and compositions for preparation of H-ARG-X-Z-Y-TYR-R
US4361673A (en) 1980-09-19 1982-11-30 American Home Products Corporation Polypeptide compositions
US4305852A (en) * 1980-10-20 1981-12-15 American Home Products Corporation Polypeptide compositions

Also Published As

Publication number Publication date
KR940001007B1 (ko) 1994-02-08
ATE63748T1 (de) 1991-06-15
JPH07165791A (ja) 1995-06-27
DE3484616D1 (de) 1991-06-27
KR850004594A (ko) 1985-07-25
AU3565284A (en) 1985-05-23
FI86860C (fi) 1992-10-26
CA1269498A (fr) 1990-05-22
FI844510A0 (fi) 1984-11-16
JPH0753752B2 (ja) 1995-06-07
NO166943B (no) 1991-06-10
NZ210194A (en) 1988-11-29
ZA848973B (en) 1986-06-25
US4505853A (en) 1985-03-19
AU579595B2 (en) 1988-12-01
JP2633481B2 (ja) 1997-07-23
DK167928B1 (da) 1994-01-03
EP0146266A2 (fr) 1985-06-26
IL73533A0 (en) 1985-02-28
DK545584D0 (da) 1984-11-16
JPS60123498A (ja) 1985-07-02
DK545584A (da) 1985-05-19
IL73533A (en) 1988-06-30
FI844510L (fi) 1985-05-19
NO844579L (no) 1985-05-20
EP0146266B1 (fr) 1991-05-22
FI86860B (fi) 1992-07-15
EP0146266A3 (en) 1987-08-12

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Legal Events

Date Code Title Description
MM1K Lapsed by not paying the annual fees

Free format text: LAPSED IN MAY 2002