NO163451C - Analogifremgangsmaate for fremstilling av terapeutisk aktive aminomethyloxooxazolidinylbenzenderivater. - Google Patents

Analogifremgangsmaate for fremstilling av terapeutisk aktive aminomethyloxooxazolidinylbenzenderivater.

Info

Publication number
NO163451C
NO163451C NO842273A NO842273A NO163451C NO 163451 C NO163451 C NO 163451C NO 842273 A NO842273 A NO 842273A NO 842273 A NO842273 A NO 842273A NO 163451 C NO163451 C NO 163451C
Authority
NO
Norway
Prior art keywords
aminomethyloxooxazolidinyl
preparation
therapeutic active
analogy procedure
benzen
Prior art date
Application number
NO842273A
Other languages
English (en)
Norwegian (no)
Other versions
NO163451B (no
NO842273L (no
Inventor
Walter Adelman Gregory
Original Assignee
Du Pont
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Du Pont filed Critical Du Pont
Publication of NO842273L publication Critical patent/NO842273L/no
Priority to NO892178A priority Critical patent/NO169122C/no
Publication of NO163451B publication Critical patent/NO163451B/no
Publication of NO163451C publication Critical patent/NO163451C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18—Oxygen atoms
    • C07D263/20—Oxygen atoms attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18—Oxygen atoms
    • C07D263/20—Oxygen atoms attached in position 2
    • C07D263/24—Oxygen atoms attached in position 2 with hydrocarbon radicals, substituted by oxygen atoms, attached to other ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NO842273A 1983-06-07 1984-06-06 Analogifremgangsmaate for fremstilling av terapeutisk aktive aminomethyloxooxazolidinylbenzenderivater. NO163451C (no)

Priority Applications (1)

Application Number Priority Date Filing Date Title
NO892178A NO169122C (no) 1983-06-07 1989-05-30 2-oxazolidinderivater for anvendelse som utgangsmaterialer for fremstilling av aminomethyloxooxazolidinylbenzenderivater

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US50189783A 1983-06-07 1983-06-07
US57833284A 1984-02-14 1984-02-14

Publications (3)

Publication Number Publication Date
NO842273L NO842273L (no) 1984-12-10
NO163451B NO163451B (no) 1990-02-19
NO163451C true NO163451C (no) 1990-05-30

Family

ID=27053956

Family Applications (1)

Application Number Title Priority Date Filing Date
NO842273A NO163451C (no) 1983-06-07 1984-06-06 Analogifremgangsmaate for fremstilling av terapeutisk aktive aminomethyloxooxazolidinylbenzenderivater.

Country Status (16)

Country Link
EP (1) EP0127902B1 (fr)
AU (1) AU583250B2 (fr)
CA (2) CA1254213A (fr)
DE (1) DE3485162D1 (fr)
DK (1) DK279584A (fr)
ES (2) ES533097A0 (fr)
FI (1) FI83216C (fr)
GR (1) GR82361B (fr)
HU (1) HU194194B (fr)
IE (1) IE57619B1 (fr)
IL (1) IL72028A (fr)
MX (1) MX169619B (fr)
NO (1) NO163451C (fr)
NZ (1) NZ208395A (fr)
PT (1) PT78703A (fr)
SU (2) SU1505442A3 (fr)

Families Citing this family (54)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4705799A (en) * 1983-06-07 1987-11-10 E. I. Du Pont De Nemours And Company Aminomethyl oxooxazolidinyl benzenes useful as antibacterial agents
CA1260948A (fr) * 1984-12-05 1989-09-26 E. I. Du Pont De Nemours And Company Derives d'aminomethyloxo-oxazolidinylbenzene, agents antibacteriens
US5099026A (en) * 1986-09-12 1992-03-24 Crater Davis H Fluorochemical oxazolidinones
CA1323370C (fr) * 1986-09-12 1993-10-19 Davis H. Crater Oxazolidinones fluoroaliphatiques
US5039690A (en) * 1987-10-09 1991-08-13 Du Pont Merck Pharmaceutical Company Aminomethyl oxooxazolidinyl oxa or thia cycloalkylbenzene derivatives useful as antibacterial agents
US5032605A (en) * 1987-10-09 1991-07-16 Du Pont Merck Pharmaceutical Company Aminomethyl oxooxazolidinyl oxa or thia cycloalkylbenzene derivatives useful as antibacterial agents
US4965268A (en) * 1987-10-09 1990-10-23 E. I. Du Pont De Nemours And Company Aminomethyl oxooxazolidinyl cycloalkylbenzene derivatives useful as antibacterial agents
US5036093A (en) * 1987-10-09 1991-07-30 Du Pont Merck Pharmaceutical Aminomethyl oxooxazolidinyl azacycloalkylbenzene derivatives useful as antibacterial agents
US4921869A (en) * 1987-10-09 1990-05-01 E. I. Du Pont De Nemours And Company Aminomethyl oxooxazolidinyl cycloalkylbenzene derivatives useful as antibacterial agents
US4985429A (en) * 1987-10-09 1991-01-15 E. I. Du Pont De Nemours And Company Aminomethyl oxooxazolidinyl cycloalkylbenzene derivatives useful as antibacterial agents
US4801600A (en) * 1987-10-09 1989-01-31 E. I. Du Pont De Nemours And Company Aminomethyl oxooxazolidinyl cycloalkylbenzene derivatives useful as antibacterial agents
US5036092A (en) * 1987-10-09 1991-07-30 Du Pont Merck Pharmaceutical Aminomethyl oxooxazolidinyl azacycloalkylbenzene derivatives useful as antibacterial agents
US4942183A (en) * 1987-10-16 1990-07-17 E. I. Du Pont De Nemours And Company Aminomethyl oxooxazolidinyl aroylbenzene derivatives useful as antibacterial agents
CA1320730C (fr) * 1987-10-16 1993-07-27 The Du Pont Merck Pharmaceutical Company Derives d'aminomethyloxooxazolidinylaroylbenzene, agents antibacteriens
ATE95176T1 (de) * 1987-10-21 1993-10-15 Du Pont Merck Pharma Aminomethyl-oxo-oxazolidinyl-ethenylbenzenderivate, nuetzlich als antibakterielles mittel.
US4977173A (en) * 1987-10-21 1990-12-11 E. I. Du Pont De Nemours And Company Aminomethyl oxooxazolidinyl ethenylbenzene derivatives useful as antibacterial agents
US4948801A (en) * 1988-07-29 1990-08-14 E. I. Du Pont De Nemours And Company Aminomethyloxooxazolidinyl arylbenzene derivatives useful as antibacterial agents
US5225565A (en) * 1988-09-15 1993-07-06 The Upjohn Company Antibacterial 3-(fused-ring substituted)phenyl-5β-amidomethyloxazolidin-2-ones
US5182403A (en) * 1988-09-15 1993-01-26 The Upjohn Company Substituted 3(5'indazolyl) oxazolidin-2-ones
WO1990002744A1 (fr) * 1988-09-15 1990-03-22 The Upjohn Company 5-beta-amidomethyle-oxazolidine-2-ones a substitution en position 3
US5231188A (en) * 1989-11-17 1993-07-27 The Upjohn Company Tricyclic [6.5.51]-fused oxazolidinone antibacterial agents
JP3176626B2 (ja) * 1991-11-01 2001-06-18 ファルマシア・アンド・アップジョン・カンパニー 抗菌剤として有用な置換アリール−およびヘテロアリールフェニルオキサゾリジノン類
RU2119484C1 (ru) * 1992-12-08 1998-09-27 Дзе Апджон Компани Тропонзамещенный фенилоксазолидинон или его фармацевтически приемлемые соли или гидраты
TW299332B (fr) * 1992-12-08 1997-03-01 Upjohn Co
MY115155A (en) * 1993-09-09 2003-04-30 Upjohn Co Substituted oxazine and thiazine oxazolidinone antimicrobials.
US5688792A (en) * 1994-08-16 1997-11-18 Pharmacia & Upjohn Company Substituted oxazine and thiazine oxazolidinone antimicrobials
SK282869B6 (sk) * 1994-10-26 2003-01-09 Pharmacia + Upjohn Company Antimikrobiálne fenyloxazolidinóny
MX9703040A (es) * 1995-09-12 1997-07-31 Upjohn Co Antimicrobianos de feniloxazolidinona.
GB9601666D0 (en) * 1996-01-27 1996-03-27 Zeneca Ltd Chemical compounds
GB9702213D0 (en) * 1996-02-24 1997-03-26 Zeneca Ltd Chemical compounds
GB9609919D0 (en) * 1996-05-11 1996-07-17 Zeneca Ltd Chemical compounds
US6218413B1 (en) 1997-05-30 2001-04-17 Pharmacia & Upjohn Company Oxazolidinone antibacterial agents having a thiocarbonyl functionality
US6255304B1 (en) 1997-05-30 2001-07-03 Pharmacia & Upjohn Company Oxazolidinone antibacterial agents having a thiocarbonyl functionality
GB9717807D0 (en) 1997-08-22 1997-10-29 Zeneca Ltd Chemical compounds
GB9717804D0 (en) 1997-08-22 1997-10-29 Zeneca Ltd Chemical compounds
AU9001598A (en) * 1997-09-11 1999-03-29 Hokuriku Seiyaku Co. Ltd Thiourea derivatives
GB9725244D0 (en) 1997-11-29 1998-01-28 Zeneca Ltd Chemical compounds
KR20010015910A (ko) * 1998-01-23 2001-02-26 로렌스 티. 마이젠헬더 옥사졸리디논 조합 라이브러리, 조성물 및 제조 방법
GB9821938D0 (en) 1998-10-09 1998-12-02 Zeneca Ltd Chemical compounds
NZ515754A (en) 1999-05-27 2003-10-31 Upjohn Co Bicyclic oxazolidinone compounds, pharmaceuticals thereof and their use as antibacterial agents
US6297242B1 (en) * 1999-08-12 2001-10-02 Ortho-Mcneil Pharmaceutical, Inc. N-substituted amidine and guanidine oxazolidinone antibacterials and methods of use thereof
GB9928568D0 (en) 1999-12-03 2000-02-02 Zeneca Ltd Chemical compounds
US6518285B2 (en) * 1999-12-21 2003-02-11 Ortho Mcneil Pharmaceutical, Inc. Piperidinyloxy and pyrrolidinyloxy oxazolidinone antibacterials
DE19962924A1 (de) 1999-12-24 2001-07-05 Bayer Ag Substituierte Oxazolidinone und ihre Verwendung
GB0009803D0 (en) 2000-04-25 2000-06-07 Astrazeneca Ab Chemical compounds
ATE321024T1 (de) 2000-10-17 2006-04-15 Pharmacia & Upjohn Co Llc Verfahren zur herstellung von oxazolidinonverbindungen
DE10129725A1 (de) 2001-06-20 2003-01-02 Bayer Ag Kombinationstherapie substituierter Oxazolidinone
DE10300111A1 (de) 2003-01-07 2004-07-15 Bayer Healthcare Ag Verfahren zur Herstellung von 5-Chlor-N-({(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)-phenyl]-1,3-oxazolidin-5-yl}-methyl)-2-thiophencarboxamid
DE10355461A1 (de) 2003-11-27 2005-06-23 Bayer Healthcare Ag Verfahren zur Herstellung einer festen, oral applizierbaren pharmazeutischen Zusammensetzung
EP1685841A1 (fr) 2005-01-31 2006-08-02 Bayer Health Care Aktiengesellschaft Prevention et traitement de troubles thromboemboliques
DE102005045518A1 (de) 2005-09-23 2007-03-29 Bayer Healthcare Ag 2-Aminoethoxyessigsäure-Derivate und ihre Verwendung
CA2624310C (fr) 2005-10-04 2014-01-07 Bayer Healthcare Ag Forme polymorphique de 5 chloro n ({5s) 2 oxo 3 [4 (3 oxo 4 morpholinyl)phenyl] 1,3 oxazolidin 5 yl} methyl) 2 thiophenecarboxamidel)-2-thiophenecarboxamide
DE102005047561A1 (de) 2005-10-04 2007-04-05 Bayer Healthcare Ag Feste, oral applizierbare pharmazeutische Darreichungsformen mit schneller Wirkstofffreisetzung
KR101653570B1 (ko) 2011-03-30 2016-09-02 주식회사 레고켐 바이오사이언스 신규한 옥사졸리디논 유도체 및 이를 함유하는 의약 조성물

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1222708A (en) * 1968-10-22 1971-02-17 Delalande Sa Novel 5-(n-substituted aminomethyl)-2-oxazolidinones and their process of preparation
US4348393A (en) * 1978-06-09 1982-09-07 Delalande S.A. N-Aryl oxazolidinones, oxazolidinethiones, pyrrolidinones, pyrrolidines and thiazolidinones
US4340606A (en) * 1980-10-23 1982-07-20 E. I. Du Pont De Nemours And Company 3-(p-Alkylsulfonylphenyl)oxazolidinone derivatives as antibacterial agents
FR2500450A1 (fr) * 1981-02-25 1982-08-27 Delalande Sa Nouveaux derives aminomethyl-5 oxazolidiniques, leur procede de preparation et leur application en therapeutique
AU560666B2 (en) * 1981-12-04 1987-04-16 E.I. Du Pont De Nemours And Company P(2-oxo oxazolidinyl)benzene sulphonamides
CA1260948A (fr) * 1984-12-05 1989-09-26 E. I. Du Pont De Nemours And Company Derives d'aminomethyloxo-oxazolidinylbenzene, agents antibacteriens

Also Published As

Publication number Publication date
EP0127902A2 (fr) 1984-12-12
AU583250B2 (en) 1989-04-27
IE841407L (en) 1984-12-07
FI83216C (fi) 1991-06-10
AU2909984A (en) 1984-12-13
MX169619B (es) 1993-07-15
ES8802037A1 (es) 1988-03-16
HUT34462A (en) 1985-03-28
FI842273A0 (fi) 1984-06-06
IL72028A (en) 1988-05-31
NZ208395A (en) 1987-07-31
HU194194B (en) 1988-01-28
IE57619B1 (en) 1993-02-10
EP0127902B1 (fr) 1991-10-16
DK279584A (da) 1984-12-08
ES8506659A1 (es) 1985-08-01
GR82361B (fr) 1984-12-13
EP0127902A3 (en) 1987-09-02
DE3485162D1 (de) 1991-11-21
NO163451B (no) 1990-02-19
PT78703A (en) 1984-07-01
IL72028A0 (en) 1984-10-31
ES533097A0 (es) 1985-08-01
ES540812A0 (es) 1988-03-16
NO842273L (no) 1984-12-10
DK279584D0 (da) 1984-06-06
CA1254213A (fr) 1989-05-16
FI842273A (fi) 1984-12-08
SU1426451A3 (ru) 1988-09-23
FI83216B (fi) 1991-02-28
SU1505442A3 (ru) 1989-08-30
CA1275652C (fr) 1990-10-30

Similar Documents

Publication Publication Date Title
NO163451C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive aminomethyloxooxazolidinylbenzenderivater.
NO162764C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive indolinderivater.
NO158099C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive karbostyrilderivater.
NO165239C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive 1-benzyl-aminoalkyl-pyrrolidinon-derivater.
NO165192C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive glyserolderivater.
NO156864C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive piperinderivater.
NO163406C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive imidazokinolinonderivater.
NO862477D0 (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive 2-arylimidazol-derivater.
NO152129C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive omega-cyan-1, omega-difenyl-azaalkanderivater
NO831610L (no) Fremgangsmaate for fremstilling av terapeutisk aktive oxicamderivater.
NO164301C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive cefalosporinderivater.
NO845176L (no) Fremgangsmaate for fremstilling av terapeutisk aktive 4h-3,1-benzoksazin-4-on-derivater
NO161562C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive ergolinderivater.
NO164169C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive benzothiazinderivater.
NO159930C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive indeno-pyridazinon-derivater.
NO161676C (no) Analogifremgangsm te til fremstilling av terapeutisk aktive mitosanderivater.
NO161559C (no) Analogifremgangsmaate til fremstilling av terapeutisk aktive triazolderivater.
NO164897C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive oxazolidinonderivater.
NO158941C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive 4-piperidino-kinazolinderivater.
NO160079C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive cefem-derivater.
NO161738C (no) Analogifremgangsm te for fremstilling av terapeutisk aktive imidazolinderivater.
NO158739C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive 2-piperazinopyrimidinderivater.
NO160511C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive fenyl-cyklo-butanderivater.
NO168478C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive vinylthioacetamido-oxacefalosporinderivater.
NO160512C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive karbostyrilderivater.