NO162906C - Analogifremgangsmaate ved fremstilling av delta22- ellerdelta23- 26,26,26,27,27,27- heksafluor-1alfa,25-dihydroksycholecalciferol. - Google Patents
Analogifremgangsmaate ved fremstilling av delta22- ellerdelta23- 26,26,26,27,27,27- heksafluor-1alfa,25-dihydroksycholecalciferol.Info
- Publication number
- NO162906C NO162906C NO854576A NO854576A NO162906C NO 162906 C NO162906 C NO 162906C NO 854576 A NO854576 A NO 854576A NO 854576 A NO854576 A NO 854576A NO 162906 C NO162906 C NO 162906C
- Authority
- NO
- Norway
- Prior art keywords
- delta23
- delta22
- 1alfa
- hexafluor
- dihydroxycholecalciferol
- Prior art date
Links
- GMRQFYUYWCNGIN-NKMMMXOESA-N calcitriol Chemical compound C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@@H](CCCC(C)(C)O)C)=C\C=C1\C[C@@H](O)C[C@H](O)C1=C GMRQFYUYWCNGIN-NKMMMXOESA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C7/00—Purification; Separation; Use of additives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
- C07C49/703—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups
- C07C49/743—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups having unsaturation outside the rings, e.g. humulones, lupulones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
- C07C33/40—Halogenated unsaturated alcohols
- C07C33/44—Halogenated unsaturated alcohols containing rings other than six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/27—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation
- C07C45/30—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation with halogen containing compounds, e.g. hypohalogenation
- C07C45/305—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation with halogen containing compounds, e.g. hypohalogenation with halogenochromate reagents, e.g. pyridinium chlorochromate
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Nutrition Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Analytical Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Water Supply & Treatment (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/672,059 US4613594A (en) | 1984-11-16 | 1984-11-16 | Fluorinated vitamin D3 compounds |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO854576L NO854576L (no) | 1986-05-20 |
| NO162906B NO162906B (no) | 1989-11-27 |
| NO162906C true NO162906C (no) | 1990-03-07 |
Family
ID=24696990
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO854576A NO162906C (no) | 1984-11-16 | 1985-11-15 | Analogifremgangsmaate ved fremstilling av delta22- ellerdelta23- 26,26,26,27,27,27- heksafluor-1alfa,25-dihydroksycholecalciferol. |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US4613594A (no) |
| EP (1) | EP0182298B1 (no) |
| JP (1) | JPS61122237A (no) |
| KR (1) | KR930007993B1 (no) |
| AR (1) | AR242767A1 (no) |
| AT (1) | ATE48412T1 (no) |
| AU (1) | AU588012B2 (no) |
| CA (1) | CA1286693C (no) |
| DE (1) | DE3574587D1 (no) |
| DK (1) | DK159652C (no) |
| ES (1) | ES8801198A1 (no) |
| FI (1) | FI84599C (no) |
| HU (1) | HU194162B (no) |
| IE (1) | IE58851B1 (no) |
| IL (1) | IL77052A (no) |
| MC (1) | MC1709A1 (no) |
| NO (1) | NO162906C (no) |
| NZ (1) | NZ214175A (no) |
| PH (1) | PH21540A (no) |
| PT (1) | PT81502B (no) |
| ZA (1) | ZA858151B (no) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS63196556A (ja) * | 1987-02-10 | 1988-08-15 | Taisho Pharmaceut Co Ltd | 含フツ素ビタミンｄ誘導体 |
| US5366736A (en) * | 1989-02-16 | 1994-11-22 | University Of Georgia Research Foundation, Inc. | Vitamin D derivative feed compositions and methods of use |
| US5316770A (en) * | 1989-02-16 | 1994-05-31 | University Of Georgia Research Foundation, Inc. | Vitamin D derivative feed compositions and methods of use |
| AU5185790A (en) * | 1989-02-16 | 1990-09-05 | University Of Georgia Research Foundation, Inc., The | Treatment of tibial dyschondroplasia |
| JP2525478B2 (ja) * | 1989-03-01 | 1996-08-21 | 帝人株式会社 | 安定性の改良された活性型ビタミンｄ▲下３▼類固型製剤 |
| AU650751B2 (en) * | 1991-05-28 | 1994-06-30 | Wisconsin Alumni Research Foundation | Novel synthesis of 19-nor vitamin D compounds |
| US5278155A (en) * | 1991-06-05 | 1994-01-11 | Daikin Industries, Ltd. | Fluorine-containing vitamin D3 analogues and cell differentiation-inducing agent containing the same |
| US5206230A (en) * | 1991-06-05 | 1993-04-27 | Daikin Industries, Ltd. | Fluorine-containing vitamin D3 analogues and pharmaceutical composition containing the same |
| EP0521550B1 (en) * | 1991-07-05 | 1996-09-18 | Duphar International Research B.V | Vitamin D compound, method of preparing this compound and intermediate therefor |
| CA2096105A1 (en) * | 1992-10-07 | 1994-04-08 | Enrico Giuseppe Baggiolini (Deceased) | Vitamin d3 fluorinated analogs |
| US5753638A (en) * | 1992-10-07 | 1998-05-19 | Hoffmann-La Roche Inc. | Method of treating hyperproliferative skin disease with Vitamin D3 fluorinated analogs |
| US5547947A (en) * | 1993-03-11 | 1996-08-20 | Hoffmann-La Roche Inc. | Methods of treatment |
| US5552392A (en) * | 1993-11-03 | 1996-09-03 | Wisconsin Alumni Research Foundation | Method of treating hypoparathyroidism with (20S) vitamin D compounds |
| US5428029A (en) * | 1993-11-24 | 1995-06-27 | Hoffmann-La Roche Inc. | Vitamin D3 fluorinated analogs |
| US5872113A (en) * | 1997-05-16 | 1999-02-16 | Syntex (U.S.A.) Inc. | Fluorinated vitamin D3 analogs |
| AU2005303773A1 (en) | 2004-11-12 | 2006-05-18 | Bioxell Spa | Combined use of vitamin D derivatives and anti-proliferative agents for treating bladder cancer |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4248791A (en) * | 1980-02-04 | 1981-02-03 | Wisconsin Alumni Research Foundation | 25-Hydroxy-26,26,26,27,27,27-hexafluorocholecalciferol |
| JPS57149224A (en) * | 1981-03-13 | 1982-09-14 | Chugai Pharmaceut Co Ltd | Tumor-suppressing agent |
| US4358406A (en) * | 1981-07-27 | 1982-11-09 | Wisconsin Alumni Research Foundation | 26,26,26,27,27,27-Hexafluoro-1α,25-dihydroxycholecalciferol and process for preparing same |
| US4411833A (en) * | 1982-05-26 | 1983-10-25 | Wisconsin Alumni Research Foundation | Method for preparing 26,26,26,27,27,27-hexafluoro-1α,25-dihydroxycholesterol |
| DE3471928D1 (en) * | 1983-01-28 | 1988-07-14 | Hoffmann La Roche | Process for the preparation of cholecalciferol derivatives |
| US4508651A (en) * | 1983-03-21 | 1985-04-02 | Hoffmann-La Roche Inc. | Synthesis of 1α,25-dihydroxyergocalciferol |
| US4505906A (en) * | 1984-01-30 | 1985-03-19 | Wisconsin Alumni Research Foundation | Hydroxyvitamin D2 isomers |
| US4521410A (en) * | 1984-05-03 | 1985-06-04 | The General Hospital Corporation | Vitamin D glycosyl orthoesters |
-
1984
- 1984-11-16 US US06/672,059 patent/US4613594A/en not_active Expired - Fee Related
-
1985
- 1985-10-23 ZA ZA858151A patent/ZA858151B/xx unknown
- 1985-11-13 CA CA000495246A patent/CA1286693C/en not_active Expired - Fee Related
- 1985-11-13 NZ NZ214175A patent/NZ214175A/xx unknown
- 1985-11-13 DK DK524585A patent/DK159652C/da not_active IP Right Cessation
- 1985-11-14 DE DE8585114493T patent/DE3574587D1/de not_active Expired - Lifetime
- 1985-11-14 AT AT85114493T patent/ATE48412T1/de not_active IP Right Cessation
- 1985-11-14 FI FI854492A patent/FI84599C/fi not_active IP Right Cessation
- 1985-11-14 EP EP85114493A patent/EP0182298B1/de not_active Expired
- 1985-11-14 IL IL77052A patent/IL77052A/xx not_active IP Right Cessation
- 1985-11-14 MC MC851803A patent/MC1709A1/xx unknown
- 1985-11-14 AR AR85302272A patent/AR242767A1/es active
- 1985-11-15 JP JP60255154A patent/JPS61122237A/ja active Granted
- 1985-11-15 PH PH33060A patent/PH21540A/en unknown
- 1985-11-15 HU HU854361A patent/HU194162B/hu not_active IP Right Cessation
- 1985-11-15 PT PT81502A patent/PT81502B/pt not_active IP Right Cessation
- 1985-11-15 ES ES548910A patent/ES8801198A1/es not_active Expired
- 1985-11-15 IE IE287585A patent/IE58851B1/en not_active IP Right Cessation
- 1985-11-15 NO NO854576A patent/NO162906C/no unknown
- 1985-11-15 KR KR1019850008546A patent/KR930007993B1/ko not_active IP Right Cessation
- 1985-12-09 AU AU50898/85A patent/AU588012B2/en not_active Ceased
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