NO158219C - Fremgangsmaate for fremstilling av et krystallinsk hemi-syresalt av et cefalosporinderivat. - Google Patents

Fremgangsmaate for fremstilling av et krystallinsk hemi-syresalt av et cefalosporinderivat.

Info

Publication number
NO158219C
NO158219C NO793989A NO793989A NO158219C NO 158219 C NO158219 C NO 158219C NO 793989 A NO793989 A NO 793989A NO 793989 A NO793989 A NO 793989A NO 158219 C NO158219 C NO 158219C
Authority
NO
Norway
Prior art keywords
crystallinic
hemi
procedure
preparation
acid salt
Prior art date
Application number
NO793989A
Other languages
English (en)
Norwegian (no)
Other versions
NO793989L (no
NO158219B (no
Inventor
Hideaki Natsugari
Iwao Mikami
Michihiko Ochiai
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of NO793989L publication Critical patent/NO793989L/no
Publication of NO158219B publication Critical patent/NO158219B/no
Publication of NO158219C publication Critical patent/NO158219C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36—Methylene radicals, substituted by sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NO793989A 1978-12-11 1979-12-07 Fremgangsmaate for fremstilling av et krystallinsk hemi-syresalt av et cefalosporinderivat. NO158219C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP15337778A JPS5579393A (en) 1978-12-11 1978-12-11 Cephalosporin derivative and its preparation

Publications (3)

Publication Number Publication Date
NO793989L NO793989L (no) 1980-06-12
NO158219B NO158219B (no) 1988-04-25
NO158219C true NO158219C (no) 1988-08-03

Family

ID=15561123

Family Applications (1)

Application Number Title Priority Date Filing Date
NO793989A NO158219C (no) 1978-12-11 1979-12-07 Fremgangsmaate for fremstilling av et krystallinsk hemi-syresalt av et cefalosporinderivat.

Country Status (18)

Country Link
US (1) US4298607A (de)
JP (1) JPS5579393A (de)
BE (1) BE880518A (de)
CA (1) CA1128499A (de)
CH (1) CH646437A5 (de)
DE (1) DE2949485A1 (de)
DK (1) DK159785C (de)
ES (1) ES8100299A1 (de)
FR (1) FR2444042A1 (de)
GB (1) GB2036746B (de)
GR (1) GR74078B (de)
HK (1) HK9486A (de)
IT (1) IT1126514B (de)
MY (1) MY8500456A (de)
NL (1) NL190487C (de)
NO (1) NO158219C (de)
SE (1) SE447117B (de)
SG (1) SG93185G (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR78221B (de) * 1980-02-01 1984-09-26 Ciba Geigy Ag
US4400503A (en) * 1981-10-30 1983-08-23 Eli Lilly And Company Purification of syn-7-[[(2-amino-4-thiazolyl)(methoxyimino) acetyl]amino]-3-methyl-3-cephem-4-carboxylic acid
US4594417A (en) * 1981-10-30 1986-06-10 Eli Lilly Company Crystalline antibiotic salt
US4902683A (en) * 1984-10-25 1990-02-20 The Upjohn Company Crystalline cephalosporin hydrohalide salts
EP0638573A1 (de) * 1993-08-10 1995-02-15 Lucky Ltd. Kristalline Hydrate eines Cephalosporins und Verfahren zu ihrer Herstellung
ATE440101T1 (de) 2003-03-27 2009-09-15 Basilea Pharmaceutica Ag Cephalosporin in kristalliner form

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK154939C (da) * 1974-12-19 1989-06-12 Takeda Chemical Industries Ltd Analogifremgangsmaade til fremstilling af thiazolylacetamido-cephemforbindelser eller farmaceutisk acceptable salte eller estere deraf
FR2345153A1 (fr) * 1976-03-25 1977-10-21 Roussel Uclaf Nouvelles alcoyloximes derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
US4166115A (en) * 1976-04-12 1979-08-28 Fujisawa Pharmaceutical Co., Ltd. Syn 7-oxoimino substituted derivatives of cephalosporanic acid
GB1576625A (en) * 1976-04-12 1980-10-08 Fujisawa Pharmaceutical Co Syn isomer 3,7 disubstituted 3 cephem 4 carboxylic acid compounds and processes for the preparation thereof
JPS603314B2 (ja) * 1976-08-31 1985-01-26 武田薬品工業株式会社 セフアロスポリン誘導体およびその製造法
DE2714880A1 (de) * 1977-04-02 1978-10-26 Hoechst Ag Cephemderivate und verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
BE880518A (fr) 1980-06-10
ES486680A0 (es) 1980-11-01
GB2036746B (en) 1983-02-09
SG93185G (en) 1987-03-27
NO793989L (no) 1980-06-12
NL7908869A (nl) 1980-06-13
DK524579A (da) 1980-06-12
GR74078B (de) 1984-06-06
DK159785B (da) 1990-12-03
DE2949485A1 (de) 1980-06-19
SE7909998L (sv) 1980-06-12
MY8500456A (en) 1985-12-31
US4298607A (en) 1981-11-03
SE447117B (sv) 1986-10-27
DE2949485C2 (de) 1989-06-08
FR2444042A1 (fr) 1980-07-11
NL190487B (nl) 1993-10-18
ES8100299A1 (es) 1980-11-01
CA1128499A (en) 1982-07-27
GB2036746A (en) 1980-07-02
IT1126514B (it) 1986-05-21
CH646437A5 (de) 1984-11-30
NL190487C (nl) 1994-03-16
NO158219B (no) 1988-04-25
JPS5579393A (en) 1980-06-14
FR2444042B1 (de) 1983-06-24
JPS636552B2 (de) 1988-02-10
HK9486A (en) 1986-02-14
DK159785C (da) 1991-04-22
IT7927924A0 (it) 1979-12-07

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