NO156067C - Substrat for bestemmelse av plasminogenaktivatorer. - Google Patents

Substrat for bestemmelse av plasminogenaktivatorer.

Info

Publication number
NO156067C
NO156067C NO771869A NO771869A NO156067C NO 156067 C NO156067 C NO 156067C NO 771869 A NO771869 A NO 771869A NO 771869 A NO771869 A NO 771869A NO 156067 C NO156067 C NO 156067C
Authority
NO
Norway
Prior art keywords
determination
substrate
plasminogen activators
plasminogen
activators
Prior art date
Application number
NO771869A
Other languages
English (en)
Norwegian (no)
Other versions
NO771869L (no
NO156067B (no
Inventor
Lars Gundro Svendsen
Original Assignee
Pentapharm Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pentapharm Ag filed Critical Pentapharm Ag
Publication of NO771869L publication Critical patent/NO771869L/no
Publication of NO156067B publication Critical patent/NO156067B/no
Publication of NO156067C publication Critical patent/NO156067C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/0808—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0812—Tripeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/56—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2337/00—N-linked chromogens for determinations of peptidases and proteinases
    • C12Q2337/10—Anilides
    • C12Q2337/12—Para-Nitroanilides p-NA
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/968—Plasmin, i.e. fibrinolysin
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/972—Plasminogen activators
    • G01N2333/9723—Urokinase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/974—Thrombin
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/976—Trypsin; Chymotrypsin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Neurosurgery (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
NO771869A 1976-05-28 1977-05-27 Substrat for bestemmelse av plasminogenaktivatorer. NO156067C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH681676A CH634662A5 (de) 1976-05-28 1976-05-28 Verwendung von tripeptidderivaten zur quantitativen bestimmung von plasminogen-aktivatoren.

Publications (3)

Publication Number Publication Date
NO771869L NO771869L (no) 1977-11-29
NO156067B NO156067B (no) 1987-04-06
NO156067C true NO156067C (no) 1987-07-15

Family

ID=4315468

Family Applications (1)

Application Number Title Priority Date Filing Date
NO771869A NO156067C (no) 1976-05-28 1977-05-27 Substrat for bestemmelse av plasminogenaktivatorer.

Country Status (17)

Country Link
US (2) US4190574A (fr)
JP (1) JPS5624520B2 (fr)
AT (1) AT368550B (fr)
AU (1) AU517375B2 (fr)
BE (1) BE855085A (fr)
CA (1) CA1086614A (fr)
CH (1) CH634662A5 (fr)
DE (1) DE2724211C2 (fr)
DK (1) DK149215C (fr)
FR (1) FR2353063A1 (fr)
GB (1) GB1589738A (fr)
IL (1) IL52124A (fr)
IT (1) IT1084992B (fr)
LU (1) LU77429A1 (fr)
NL (1) NL184849C (fr)
NO (1) NO156067C (fr)
SE (1) SE444173B (fr)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5415797A (en) * 1977-06-14 1979-02-05 Seikagaku Kogyo Co Ltd Detection and measurement of toxin in cells
US4275153A (en) * 1978-08-03 1981-06-23 American Hospital Supply Corporation Analytical fluorogenic substrates for proteolytic enzymes
JPS59499B2 (ja) * 1978-11-02 1984-01-07 味の素株式会社 ペプチド誘導体
DE2903701C2 (de) * 1979-01-31 1980-10-16 Boehringer Mannheim Gmbh, 6800 Mannheim Kontrollreagens für die Bestimmung der Heparinaktivität
CA1161431A (fr) * 1979-05-11 1984-01-31 Lars G. Svendsen Derives de tripeptide
CA1161432A (fr) * 1980-02-12 1984-01-31 Lars G. Svendsen Derives de tripeptides et application pour le dosage des enzymes
DK155051C (da) * 1980-05-06 1989-07-03 Pentapharm Ag Tripeptidderivater samt fremgangsmaade til kvantitativ analyse for proteolytiske enzymer under anvendelse deraf
US4568636A (en) * 1981-03-25 1986-02-04 Pentapharm Ag Tripeptide derivatives
JPS57177985U (fr) * 1981-04-30 1982-11-11
ATE17262T1 (de) * 1981-11-02 1986-01-15 Pentapharm Ag Verfahren zur quantitativen bestimmung von blutgerinnungsfaktor xii in humanplasma.
NL8201987A (nl) * 1982-05-13 1983-12-01 Tno Werkwijze voor het bepalen van de activiteit van plasminogeenactivator van het weefseltype, alsmede voor gebruik bij deze werkwijze geschikte combinatie van het "kit"-type.
DE3244030A1 (de) * 1982-11-27 1984-05-30 Behringwerke Ag, 3550 Marburg Chromogene verbindungen, verfahren zu ihrer herstellung und ihre verwendung
DK201084A (da) * 1983-04-28 1984-10-29 Kimberly Clark Co Fremgangsmaade til bestemmelse af cathepsin b i naervaerelse af andre proteolytiske enzymer, og forbindelser til anvendelse ved fremgangsmaaden
US4753879A (en) * 1984-08-27 1988-06-28 Biogen N.V. Modified tissue plasminogen activators
JPS62126196A (ja) * 1985-11-26 1987-06-08 Nitto Boseki Co Ltd 新規なα１−アンチトリプシン測定用化合物
DE3804600A1 (de) * 1988-02-13 1989-08-24 Basf Ag Mischung aus einer thrombolytisch wirkenden und einer antithrombotischen substanz
US5115099A (en) * 1988-06-14 1992-05-19 Nitto Boseki Co., Ltd. Substrates for determination of enzyme activity and intermediates for synthesis of the substrates as well as process for producing the intermediates
CA2116786C (fr) * 1991-09-18 1997-07-22 Marc D. Porter Photometre a deux longueurs d'onde et sonde de capteur a fibre optique
US20030207402A1 (en) * 1997-08-22 2003-11-06 Erhard Kopetzki Autocatalytically activatable zymogenic precursors of proteases and their use
WO2005092850A1 (fr) * 2004-03-26 2005-10-06 Dsm Ip Assets B.V. Aminoacide et peptide conjugués d'acide aryl-alkyle destines a etre utilises en cosmetique

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE380258B (sv) * 1972-05-02 1975-11-03 Bofors Ab Nya diagnostiskt verksamma substrat med hog specificitet till trypsin och andra enzymer av typen peptidyl-peptid-hydrolaser
SE380257B (sv) * 1972-05-02 1975-11-03 Bofors Ab Nya diagnostiskt verksamma substrat med hog specificitet till trombin och andra proteolytiska enzymer av typen peptidyl-peptid-hydrolaser
DE2527932C2 (de) * 1974-07-02 1983-04-21 Pentapharm AG, 4052 Basel Säureadditionssalze von Tripeptidderivaten und deren Verwendung als Substrate zur Bestimmung von Plasmakallikrein
SE407058B (sv) * 1974-12-05 1979-03-12 Kabi Ab Nya kromogena enzymsubstrat for serinproteaser
CH622286A5 (fr) * 1975-06-23 1981-03-31 Pentapharm Ag
SE407571B (sv) * 1975-07-11 1979-04-02 Kabi Ab Nya kromogena enzymsubstrat for serinproteaser
US4061625A (en) * 1975-07-11 1977-12-06 Ab Kabi Novel chromogenic thrombin substrates

Also Published As

Publication number Publication date
DK149215C (da) 1986-08-04
FR2353063A1 (fr) 1977-12-23
SE7706275L (sv) 1977-11-29
IL52124A0 (en) 1977-07-31
JPS5624520B2 (fr) 1981-06-06
CH634662A5 (de) 1983-02-15
DK235577A (da) 1977-11-29
DE2724211C2 (de) 1987-03-05
FR2353063B1 (fr) 1980-10-24
NL7705891A (nl) 1977-11-30
DK149215B (da) 1986-03-17
ATA375877A (de) 1982-02-15
NO771869L (no) 1977-11-29
IT1084992B (it) 1985-05-28
AU517375B2 (en) 1981-07-30
IL52124A (en) 1980-11-30
CA1086614A (fr) 1980-09-30
SE444173B (sv) 1986-03-24
AT368550B (de) 1982-10-25
NL184849C (nl) 1989-11-16
US4190574A (en) 1980-02-26
JPS52146694A (fr) 1977-12-06
US4278762A (en) 1981-07-14
NL184849B (nl) 1989-06-16
GB1589738A (en) 1981-05-20
DE2724211A1 (de) 1977-12-01
BE855085A (fr) 1977-09-16
NO156067B (no) 1987-04-06
LU77429A1 (fr) 1977-09-09
AU2557177A (en) 1978-11-30

Similar Documents

Publication Publication Date Title
NO156067C (no) Substrat for bestemmelse av plasminogenaktivatorer.
AT345475B (de) Substrat
BE843245A (fr) Substrat chromogene ou fluorescent
SE7905690L (sv) Beleggning av substrat
IT1062604B (it) Substrato enzimatico cromogeno
SE407058B (sv) Nya kromogena enzymsubstrat for serinproteaser
FI773757A (fi) Foerfarande foer framstaellning av bicykliska prostaglandiner
FI773242A (fi) Specifika kromogena enzymsubstrat
DK421577A (da) Plasminogen-aktivator-kompleks
NO770429L (no) Aktivatorer for perforbindelser.
BE823771A (fr) Substrat destine a la determination des proteinases
IT1062605B (it) Substrato cromogeno per trombine ed enzimi trombinici
SE7506977L (sv) Avskalning av overkledda substrat.
FI773661A (fi) Foerfarande foer framstaellning av pappersmassa
FI772900A (fi) Foerfarande foer framstaellning av nya steroidfoereningar med en syrefunktion 19-staellningen
NO147250C (no) Anordning til utbalansering av vippeporter.
SE7706345L (sv) Fosforhaltiga aktivatorer for perforeningar
NO142265C (no) Baererbundet enzymatisk substrat.
CA1035016A (fr) Circuit de commande de polarisation pour pont a transistors
SE7713070L (sv) Elektrokemiskt forfarande for snabbestemning av patogena mikroorganismers kemoterapeutiska mottaglighet
NO773006L (no) Aktivatorer for perforbindelser.
NL7608427A (nl) Substraat voor het kweken van microoerganismen.
SE7705040L (sv) Selektivt medium for bestemning av nervaron av proteus
FI56203C (fi) Foerfarande foer uppbyggande av anlaeggning foer undertrycksytbehandling
NO143447C (no) Fremgangsmaate til konservering av groentfor.