NO156052C - Fremgangsmaate ved fremstilling av menneskeinsulin eller b-30 estere derav. - Google Patents

Fremgangsmaate ved fremstilling av menneskeinsulin eller b-30 estere derav.

Info

Publication number
NO156052C
NO156052C NO83831730A NO831730A NO156052C NO 156052 C NO156052 C NO 156052C NO 83831730 A NO83831730 A NO 83831730A NO 831730 A NO831730 A NO 831730A NO 156052 C NO156052 C NO 156052C
Authority
NO
Norway
Prior art keywords
insulan
esters
procedure
manufacturing human
human
Prior art date
Application number
NO83831730A
Other languages
English (en)
Norwegian (no)
Other versions
NO156052B (no
NO831730L (no
Inventor
Finn Hede Andresen
Per Balschmidt
Kim Ry Hejnaes
Hans Kofod
Original Assignee
Nordisk Insulinlab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nordisk Insulinlab filed Critical Nordisk Insulinlab
Publication of NO831730L publication Critical patent/NO831730L/no
Publication of NO156052B publication Critical patent/NO156052B/no
Publication of NO156052C publication Critical patent/NO156052C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Toxicology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
NO83831730A 1982-06-07 1983-05-13 Fremgangsmaate ved fremstilling av menneskeinsulin eller b-30 estere derav. NO156052C (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DK254582 1982-06-07
DK254682 1982-06-07
PCT/DK1982/000082 WO1983001074A1 (en) 1981-09-15 1982-09-14 Enzymatic preparation of human insulin or b-30 esters thereof

Publications (3)

Publication Number Publication Date
NO831730L NO831730L (no) 1983-05-13
NO156052B NO156052B (no) 1987-04-06
NO156052C true NO156052C (no) 1987-07-15

Family

ID=26066590

Family Applications (1)

Application Number Title Priority Date Filing Date
NO83831730A NO156052C (no) 1982-06-07 1983-05-13 Fremgangsmaate ved fremstilling av menneskeinsulin eller b-30 estere derav.

Country Status (11)

Country Link
US (1) US4601979A (da)
EP (1) EP0088117B1 (da)
JP (1) JPS58501455A (da)
AU (1) AU551174B2 (da)
CA (1) CA1174623A (da)
DK (1) DK149457C (da)
ES (1) ES8400772A1 (da)
FI (1) FI78119C (da)
IT (1) IT1189353B (da)
NO (1) NO156052C (da)
WO (1) WO1983001074A1 (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0092829B1 (en) * 1982-04-23 1990-11-07 Wako Pure Chemical Industries, Ltd. Process for semi-synthesis of human insulin and alkaline protease for use therein
EP0294851A3 (de) * 1987-06-12 1990-05-09 Berlin-Chemie Ag Verfahren zur Herstellung von Humaninsulin und seinen Derivaten
US5130236A (en) * 1989-12-07 1992-07-14 Eli Lilly And Company Process for producing des(64,65)-proinsulin
CN1276731A (zh) 1997-10-24 2000-12-13 伊莱利利公司 不溶性胰岛素组合物
CO4970787A1 (es) * 1997-12-23 2000-11-07 Lilly Co Eli Composiciones insolubles de insulina y derivados de insulina que controlan la glucosa sanguinea
US6323311B1 (en) 1999-09-22 2001-11-27 University Of Utah Research Foundation Synthesis of insulin derivatives
CA2464616C (en) 2001-11-19 2012-07-24 Are Bogsnes Process for preparing insulin compounds
US7396903B2 (en) * 2001-11-19 2008-07-08 Novo Nordisk A/S Process for preparing insulin compounds
US8173840B2 (en) * 2003-07-29 2012-05-08 Signature R&D Holdings, Llc Compounds with high therapeutic index
US7589233B2 (en) * 2003-07-29 2009-09-15 Signature R&D Holdings, Llc L-Threonine derivatives of high therapeutic index
CN105849273B (zh) * 2013-12-23 2020-01-14 拜康研究有限公司 人胰岛素甲酯的生产方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3276961A (en) * 1963-04-08 1966-10-04 Squibb & Sons Inc Process for preparing human insulin
US3903068A (en) * 1972-12-26 1975-09-02 Us Health Education & Welfare Facile synthesis of human insulin by modification of porcine insulin
JPS6339237B2 (da) * 1979-04-06 1988-08-04 Karuruberugu Baiotekunorojii Ltd As
JPS55138393A (en) * 1979-04-13 1980-10-29 Shionogi & Co Ltd Semisynthesis of insulin
JPS55138391A (en) * 1979-04-13 1980-10-29 Shionogi & Co Ltd New synthetic method of peptide derivative
JPS55138392A (en) * 1979-04-13 1980-10-29 Shionogi & Co Ltd Semisynthesis of insulin
NO153061C (no) * 1979-04-13 1986-01-08 Shionogi & Co Fremgangsmaate for fremstilling av et b30-threonininsulin
DK147437A (en) * 1980-02-11 1900-01-01 Process for preparing human insulin or threonine B30 esters of human insulin, or a salt or complex thereof
US4343898A (en) * 1980-02-11 1982-08-10 Novo Industri A/S Process for preparing esters of human insulin
DK319780A (da) * 1980-07-24 1982-01-25 Forenede Bryggerier As Fremgangsmaade til enzymatisk udskiftning af b-30 aminosyren i insuliner
DE3101382A1 (de) * 1981-01-17 1982-09-02 Hoechst Ag, 6000 Frankfurt "verfahren zur herstellung von humanisulin oder dessen derivaten aus schweineinsulin oder dessen derivaten"

Also Published As

Publication number Publication date
IT8249114A0 (it) 1982-09-14
DK213983A (da) 1983-05-13
US4601979A (en) 1986-07-22
NO156052B (no) 1987-04-06
DK149457C (da) 1991-11-25
EP0088117B1 (en) 1986-09-24
CA1174623A (en) 1984-09-18
ES515713A0 (es) 1983-11-01
AU551174B2 (en) 1986-04-17
FI78119B (fi) 1989-02-28
JPH0526469B2 (da) 1993-04-16
DK213983D0 (da) 1983-05-13
FI78119C (fi) 1989-06-12
JPS58501455A (ja) 1983-09-01
DK149457B (da) 1986-06-16
NO831730L (no) 1983-05-13
FI831157L (fi) 1983-04-06
ES8400772A1 (es) 1983-11-01
AU8953982A (en) 1983-04-08
FI831157A0 (fi) 1983-04-06
EP0088117A1 (en) 1983-09-14
IT1189353B (it) 1988-02-04
WO1983001074A1 (en) 1983-03-31

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