NO153258C - Analogifremgangsmaate ved fremstilling av terapeutisk aktive fenyl-kinolizidiner - Google Patents

Analogifremgangsmaate ved fremstilling av terapeutisk aktive fenyl-kinolizidiner

Info

Publication number
NO153258C
NO153258C NO811263A NO811263A NO153258C NO 153258 C NO153258 C NO 153258C NO 811263 A NO811263 A NO 811263A NO 811263 A NO811263 A NO 811263A NO 153258 C NO153258 C NO 153258C
Authority
NO
Norway
Prior art keywords
chinolizidines
preparation
therapeutically active
analogy procedure
active phenyl
Prior art date
Application number
NO811263A
Other languages
English (en)
Norwegian (no)
Other versions
NO811263L (no
NO153258B (no
Inventor
Rene Imhof
Emilio Kyburz
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of NO811263L publication Critical patent/NO811263L/no
Publication of NO153258B publication Critical patent/NO153258B/no
Publication of NO153258C publication Critical patent/NO153258C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D211/74—Oxygen atoms
    • C07D211/76—Oxygen atoms attached in position 2 or 6
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D455/00—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
    • C07D455/02—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing not further condensed quinolizine ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
NO811263A 1980-04-11 1981-04-10 Analogifremgangsmaate ved fremstilling av terapeutisk aktive fenyl-kinolizidiner NO153258C (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH278480 1980-04-11
CH70181 1981-02-03

Publications (3)

Publication Number Publication Date
NO811263L NO811263L (no) 1981-10-12
NO153258B NO153258B (no) 1985-11-04
NO153258C true NO153258C (no) 1986-02-12

Family

ID=25685419

Family Applications (1)

Application Number Title Priority Date Filing Date
NO811263A NO153258C (no) 1980-04-11 1981-04-10 Analogifremgangsmaate ved fremstilling av terapeutisk aktive fenyl-kinolizidiner

Country Status (18)

Country Link
US (2) US4391978A (fr)
EP (1) EP0037990B1 (fr)
AU (1) AU540599B2 (fr)
CA (1) CA1142933A (fr)
CS (1) CS222696B2 (fr)
DE (1) DE3167549D1 (fr)
DK (1) DK116181A (fr)
ES (1) ES501232A0 (fr)
FI (1) FI67700C (fr)
HU (1) HU185633B (fr)
IE (1) IE51108B1 (fr)
IL (1) IL62592A (fr)
MC (1) MC1392A1 (fr)
NO (1) NO153258C (fr)
NZ (1) NZ196682A (fr)
PH (1) PH19199A (fr)
PT (1) PT72840B (fr)
ZW (1) ZW5581A1 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK116181A (da) * 1980-04-11 1981-10-12 Hoffmann La Roche Fremgangsmaade til fremstilling af quinolizidinderivater
EP0094744A1 (fr) * 1982-04-23 1983-11-23 Beecham Group Plc Azabicyclobenzamides, leur préparation et leurs compositions pharmaceutiques
US4716172A (en) * 1986-04-10 1987-12-29 Mcneilab, Inc. 4-substituted octahydroquinolizine analgesic compounds and octahydroquinolizinium intermediates
US6770658B2 (en) 1998-09-09 2004-08-03 Inflazyme Pharmaceuticals Ltd. Substituted γ-phenyl-Δ-lactams and uses related thereto
EP1851216A2 (fr) * 2004-11-30 2007-11-07 F.Hoffmann-La Roche Ag Derives benzoquinolizine substitues en tant qu'inhibiteurs de dpp-iv pour le traitement du diabete
WO2019134985A1 (fr) 2018-01-08 2019-07-11 F. Hoffmann-La Roche Ag Octahydropyrido[1,2-alpha]pyrazines en tant qu'inhibiteurs de magl

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3394141A (en) * 1965-11-12 1968-07-23 Fabio Sparatore Z-benzyaminobenzimidazoles
US3852452A (en) * 1970-02-10 1974-12-03 Ayerst Mckenna & Harrison Benzocycloheptaisoquinoline derivatives as cns depressants
US3692791A (en) * 1970-05-18 1972-09-19 American Home Prod SUBSTITUTED 2-t-BUTYL-OCTAHYDRO-2H-QUINOLIZINES
US3948923A (en) * 1972-03-06 1976-04-06 Bayer Aktiengesellschaft Pentahydroqunolizine derivatives
US3997547A (en) * 1975-07-14 1976-12-14 Morton-Norwich Products, Inc. Phenylimino-2H-quinolizines
GB1593146A (en) * 1976-11-05 1981-07-15 Beecham Group Ltd Octahydro-quinolizinyl benzamide derivatives
MC1289A1 (fr) * 1978-10-13 1980-07-22 Hoffmann La Roche Phenyl quinolizidines
DK116181A (da) * 1980-04-11 1981-10-12 Hoffmann La Roche Fremgangsmaade til fremstilling af quinolizidinderivater
US4339582A (en) * 1981-08-18 1982-07-13 Miles Laboratories, Inc. Quinolizidine-propionanilide compounds

Also Published As

Publication number Publication date
FI811102L (fi) 1981-10-12
PH19199A (en) 1986-01-31
DK116181A (da) 1981-10-12
AU540599B2 (en) 1984-11-29
IL62592A0 (en) 1981-06-29
EP0037990B1 (fr) 1984-12-05
IE51108B1 (en) 1986-10-01
ES8207175A1 (es) 1982-09-16
CS222696B2 (en) 1983-07-29
PT72840B (en) 1983-01-10
US4684731A (en) 1987-08-04
AU6910781A (en) 1981-10-15
NZ196682A (en) 1984-03-30
ES501232A0 (es) 1982-09-16
EP0037990A1 (fr) 1981-10-21
NO811263L (no) 1981-10-12
CA1142933A (fr) 1983-03-15
FI67700C (fi) 1985-05-10
DE3167549D1 (en) 1985-01-17
IL62592A (en) 1984-12-31
MC1392A1 (fr) 1982-04-27
PT72840A (en) 1981-05-01
HU185633B (en) 1985-03-28
IE810822L (en) 1981-10-11
ZW5581A1 (en) 1981-11-18
NO153258B (no) 1985-11-04
FI67700B (fi) 1985-01-31
US4391978A (en) 1983-07-05

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