NO137896C - Analogifremgangsmaate til fremstilling av terapeutisk virksomme, optisk aktive 1,4-benzodiazepiner - Google Patents

Analogifremgangsmaate til fremstilling av terapeutisk virksomme, optisk aktive 1,4-benzodiazepiner

Info

Publication number
NO137896C
NO137896C NO853/72A NO85372A NO137896C NO 137896 C NO137896 C NO 137896C NO 853/72 A NO853/72 A NO 853/72A NO 85372 A NO85372 A NO 85372A NO 137896 C NO137896 C NO 137896C
Authority
NO
Norway
Prior art keywords
benzodiazepines
preparation
optically active
therapeutic activities
analogical procedure
Prior art date
Application number
NO853/72A
Other languages
English (en)
Norwegian (no)
Other versions
NO137896B (no
Inventor
Franjo Kajfez
Nikola Blazevic
Vitomir Sunjic
Original Assignee
Crc Ricerca Chim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Crc Ricerca Chim filed Critical Crc Ricerca Chim
Publication of NO137896B publication Critical patent/NO137896B/no
Publication of NO137896C publication Critical patent/NO137896C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24Oxygen atoms
    • C07D243/28Preparation including building-up the benzodiazepine skeleton from compounds containing no hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/006General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length of peptides containing derivatised side chain amino acids
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
NO853/72A 1971-03-17 1972-03-16 Analogifremgangsmaate til fremstilling av terapeutisk virksomme, optisk aktive 1,4-benzodiazepiner NO137896C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH386871A CH554349A (de) 1971-03-17 1971-03-17 Verfahren zur herstellung von optisch aktiven 1,3-dihydro-2h-1,4-benzodiazepin-2-onen.

Publications (2)

Publication Number Publication Date
NO137896B NO137896B (no) 1978-02-06
NO137896C true NO137896C (no) 1978-05-16

Family

ID=4265209

Family Applications (1)

Application Number Title Priority Date Filing Date
NO853/72A NO137896C (no) 1971-03-17 1972-03-16 Analogifremgangsmaate til fremstilling av terapeutisk virksomme, optisk aktive 1,4-benzodiazepiner

Country Status (16)

Country Link
AT (1) AT327909B (sv)
BE (1) BE780892A (sv)
CA (1) CA992079A (sv)
CH (1) CH554349A (sv)
DE (1) DE2212526A1 (sv)
ES (1) ES400851A1 (sv)
FR (1) FR2130342B1 (sv)
GB (2) GB1391082A (sv)
HU (1) HU165496B (sv)
IL (2) IL38991A (sv)
NL (1) NL7203536A (sv)
NO (1) NO137896C (sv)
SE (1) SE399887B (sv)
SU (1) SU453842A3 (sv)
YU (1) YU34882B (sv)
ZA (1) ZA721845B (sv)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH602672A5 (sv) * 1974-06-28 1978-07-31 Hoffmann La Roche
CH603655A5 (sv) * 1974-10-21 1978-08-31 Hoffmann La Roche
AU6420700A (en) * 1999-08-05 2001-03-05 Prescient Neuropharma Inc. Novel 1,4-benzodiazepine compounds and derivatives thereof

Also Published As

Publication number Publication date
IL38991A (en) 1976-09-30
ZA721845B (en) 1972-12-27
GB1391081A (en) 1975-04-16
NO137896B (no) 1978-02-06
FR2130342A1 (sv) 1972-11-03
SE399887B (sv) 1978-03-06
BE780892A (fr) 1972-07-17
CH554349A (de) 1974-09-30
AT327909B (de) 1976-02-25
YU69772A (en) 1979-10-31
ATA214972A (de) 1975-05-15
SU453842A3 (sv) 1974-12-15
HU165496B (sv) 1974-09-28
NL7203536A (sv) 1972-09-19
CA992079A (en) 1976-06-29
FR2130342B1 (sv) 1977-01-14
IL47123A (en) 1976-09-30
ES400851A1 (es) 1975-01-16
GB1391082A (en) 1975-04-16
YU34882B (en) 1980-04-30
IL38991A0 (en) 1972-05-30
DE2212526A1 (de) 1972-09-21

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