NO137694C - Analogifremgangsmaate for fremstilling av terapeutisk aktive benzomorfaner - Google Patents

Analogifremgangsmaate for fremstilling av terapeutisk aktive benzomorfaner

Info

Publication number
NO137694C
NO137694C NO2518/73A NO251873A NO137694C NO 137694 C NO137694 C NO 137694C NO 2518/73 A NO2518/73 A NO 2518/73A NO 251873 A NO251873 A NO 251873A NO 137694 C NO137694 C NO 137694C
Authority
NO
Norway
Prior art keywords
benzomorphans
preparation
therapeutically active
analogical procedure
analogical
Prior art date
Application number
NO2518/73A
Other languages
English (en)
Norwegian (no)
Other versions
NO137694B (no
Inventor
Herbert Merz
Adolf Langbein
Klaus Stockhaus
Helmut Wick
Original Assignee
Boehringer Sohn Ingelheim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Sohn Ingelheim filed Critical Boehringer Sohn Ingelheim
Publication of NO137694B publication Critical patent/NO137694B/no
Publication of NO137694C publication Critical patent/NO137694C/no

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/14Antitussive agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Steroid Compounds (AREA)
NO2518/73A 1972-06-19 1973-06-18 Analogifremgangsmaate for fremstilling av terapeutisk aktive benzomorfaner NO137694C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2229695A DE2229695A1 (de) 1972-06-19 1972-06-19 2-(heteroaryl-methyl)-5,9 beta-dialkyl6,7-benzomorphane, deren saeureadditionssalze sowie verfahren zu deren herstellung

Publications (2)

Publication Number Publication Date
NO137694B NO137694B (no) 1977-12-27
NO137694C true NO137694C (no) 1978-04-05

Family

ID=5848060

Family Applications (1)

Application Number Title Priority Date Filing Date
NO2518/73A NO137694C (no) 1972-06-19 1973-06-18 Analogifremgangsmaate for fremstilling av terapeutisk aktive benzomorfaner

Country Status (13)

Country Link
US (1) US3931194A (it)
JP (1) JPS5711908B2 (it)
AT (6) AT328629B (it)
BE (1) BE801079A (it)
CH (9) CH582698A5 (it)
DE (1) DE2229695A1 (it)
DK (1) DK136904C (it)
ES (8) ES416037A1 (it)
FR (1) FR2189056B1 (it)
GB (1) GB1433817A (it)
NL (1) NL7308483A (it)
NO (1) NO137694C (it)
SE (1) SE405121B (it)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2437610A1 (de) * 1974-08-05 1976-02-26 Boehringer Sohn Ingelheim Neue 5,9-beta-disubstituierte 2-tetrahydrofurfuryl-6,7-benzomorphane, deren saeureadditionssalze, ihre verwendung als arzneimittel und verfahren zu deren herstellung
GB1575009A (en) * 1976-06-21 1980-09-17 Acf Chemiefarma Nv 6,7-benzomorphan derivatives
JPS63177704A (ja) * 1987-01-16 1988-07-21 松山株式会社 農作業機連結装置
JP5470557B2 (ja) 2007-07-26 2014-04-16 ヴァイティー ファーマシューティカルズ,インコーポレイテッド 11β−ヒドロキシステロイドデヒドロゲナーゼ1型の阻害剤の合成
CL2008003407A1 (es) * 2007-11-16 2010-01-11 Boehringer Ingelheim Int Compuestos derivados de aril- y heteroarilcarbonilo de heterobiciclo sustituido; composicion farmaceutica; procedimiento de preparacion; y su uso en el tratamiento y/o prevencion de trastornos metabolicos, mediado por la inhibicion de la enzima hsd-1.
JP5490014B2 (ja) 2007-12-11 2014-05-14 ヴァイティー ファーマシューティカルズ,インコーポレイテッド 11β−ヒドロキシステロイドデヒドロゲナーゼ1型の環状尿素阻害剤
TW200934490A (en) 2008-01-07 2009-08-16 Vitae Pharmaceuticals Inc Lactam inhibitors of 11 &abgr;-hydroxysteroid dehydrogenase 1
US8592409B2 (en) 2008-01-24 2013-11-26 Vitae Pharmaceuticals, Inc. Cyclic carbazate and semicarbazide inhibitors of 11β-hydroxysteroid dehydrogenase 1
US20110028445A1 (en) * 2008-02-12 2011-02-03 Boehringer Ingelheim International Gmbh Urea derivatives of benzomorphanes and related scaffolds, medicaments containing such compounds and their use
CA2715290A1 (en) 2008-02-15 2009-08-20 Vitae Pharmaceuticals, Inc. Inhibitors of 11beta-hydroxysteroid dehydrogenase 1
WO2009134387A1 (en) 2008-05-01 2009-11-05 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
US8138178B2 (en) 2008-05-01 2012-03-20 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
US8569292B2 (en) 2008-05-01 2013-10-29 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11β-hydroxysteroid dehydrogenase 1
AR071719A1 (es) 2008-05-13 2010-07-07 Boehringer Ingelheim Int Derivados aliciclicos de acido carboxilico de benzomorfanos y estructuras relacionadas, medicamentos que contienen dichos compuestos y su uso.procesos de obtencion
TW201016691A (en) 2008-07-25 2010-05-01 Boehringer Ingelheim Int Inhibitors of 11beta-hydroxysteroid dehydrogenase 1
NZ590495A (en) 2008-07-25 2012-10-26 Vitae Pharmaceuticals Inc Dihydropyridin-phenyl-3-oxazinan-2-ones as inhibitors of 11beta-hydroxysteroid dehydrogenase 1
US8680093B2 (en) 2009-04-30 2014-03-25 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
US8927539B2 (en) 2009-06-11 2015-01-06 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11β-hydroxysteroid dehydrogenase 1 based on the 1,3-oxazinan-2-one structure
UY33001A (es) 2009-11-06 2011-05-31 Boehringer Ingelheim Int Derivados arilo y heteroarilcarbonilo de hexahidroindenopiridina y octahidrobenzoquinolina
US8933072B2 (en) 2010-06-16 2015-01-13 Vitae Pharmaceuticals, Inc. Substituted 5-,6- and 7-membered heterocycles, medicaments containing such compounds, and their use
TWI537258B (zh) 2010-11-05 2016-06-11 百靈佳殷格翰國際股份有限公司 六氫茚并吡啶及八氫苯并喹啉之芳基-及雜環芳基羰基衍生物
WO2013025664A1 (en) 2011-08-17 2013-02-21 Boehringer Ingelheim International Gmbh Indenopyridine derivatives

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE582575A (it) * 1958-09-22
FR1281227A (fr) * 1958-09-22 1962-01-12 Smith Kline French Lab Perfectionnements apportés aux procédés pour la préparation de dérivés d'aralcoylbenzomorphane
CS166802B2 (it) * 1971-02-08 1976-03-29 Boehringer Sohn Ingelheim
SE392895B (sv) * 1971-08-24 1977-04-25 Sumitomo Chemical Co Forfarande for framstellning av bensomorfanderivat och deras salter

Also Published As

Publication number Publication date
DK136904B (da) 1977-12-12
ES431515A1 (es) 1976-11-01
BE801079A (fr) 1973-12-18
ATA490074A (de) 1975-06-15
DK136904C (da) 1978-06-26
FR2189056A1 (it) 1974-01-25
ATA489474A (de) 1975-06-15
SE405121B (sv) 1978-11-20
CH582697A5 (it) 1976-12-15
ATA489774A (de) 1975-06-15
AT329200B (de) 1976-04-26
AT328627B (de) 1976-03-25
CH583229A5 (it) 1976-12-31
AT325218B (de) 1975-10-10
ATA489874A (de) 1975-07-15
CH583230A5 (it) 1976-12-31
ATA489974A (de) 1975-07-15
DE2229695A1 (de) 1974-01-31
ES431513A1 (es) 1976-11-01
NL7308483A (it) 1973-12-21
ES431514A1 (es) 1976-11-01
CH583227A5 (it) 1976-12-31
US3931194A (en) 1976-01-06
ES431511A1 (es) 1976-11-01
ES431512A1 (es) 1976-11-01
CH589649A5 (it) 1977-07-15
CH582698A5 (it) 1976-12-15
CH583228A5 (it) 1976-12-31
AU5704673A (en) 1974-12-19
CH583231A5 (it) 1976-12-31
ES416037A1 (es) 1976-02-16
JPS4961170A (it) 1974-06-13
CH589648A5 (it) 1977-07-15
AT329199B (de) 1976-04-26
GB1433817A (en) 1976-04-28
NO137694B (no) 1977-12-27
AT328629B (de) 1976-03-25
JPS5711908B2 (it) 1982-03-08
AT328628B (de) 1976-03-25
ES431516A1 (es) 1976-11-16
FR2189056B1 (it) 1976-10-22
ES431510A1 (es) 1976-11-01

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