NO122373B - - Google Patents
Download PDFInfo
- Publication number
- NO122373B NO122373B NO0247/69A NO24769A NO122373B NO 122373 B NO122373 B NO 122373B NO 0247/69 A NO0247/69 A NO 0247/69A NO 24769 A NO24769 A NO 24769A NO 122373 B NO122373 B NO 122373B
- Authority
- NO
- Norway
- Prior art keywords
- furyl
- nitro
- quinazoline
- mol
- quinazolines
- Prior art date
Links
- PLIKAWJENQZMHA-UHFFFAOYSA-N 4-aminophenol Chemical compound NC1=CC=C(O)C=C1 PLIKAWJENQZMHA-UHFFFAOYSA-N 0.000 claims description 6
- 238000000034 method Methods 0.000 claims description 5
- 238000002360 preparation method Methods 0.000 claims description 5
- VJGCQBGAYXPKAR-UHFFFAOYSA-N 2-(5-nitrofuran-2-yl)quinazoline Chemical class [N+](=O)([O-])C1=CC=C(O1)C1=NC2=CC=CC=C2C=N1 VJGCQBGAYXPKAR-UHFFFAOYSA-N 0.000 claims description 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims description 2
- ZMXDDKWLCZADIW-UHFFFAOYSA-N N,N-Dimethylformamide Chemical compound CN(C)C=O ZMXDDKWLCZADIW-UHFFFAOYSA-N 0.000 description 18
- 150000001875 compounds Chemical class 0.000 description 5
- 230000000844 anti-bacterial effect Effects 0.000 description 4
- 238000001914 filtration Methods 0.000 description 4
- 239000000203 mixture Substances 0.000 description 4
- ZLLKFYHIFIHVJA-UHFFFAOYSA-N 4-chloro-2-(5-nitrofuran-2-yl)quinazoline Chemical compound O1C([N+](=O)[O-])=CC=C1C1=NC(Cl)=C(C=CC=C2)C2=N1 ZLLKFYHIFIHVJA-UHFFFAOYSA-N 0.000 description 3
- -1 5-nitro-2-furyl Chemical group 0.000 description 3
- 238000000354 decomposition reaction Methods 0.000 description 3
- 208000015181 infectious disease Diseases 0.000 description 3
- 239000000047 product Substances 0.000 description 3
- DAVMWQFOFAMOCP-UHFFFAOYSA-N 4-[[2-(5-nitrofuran-2-yl)quinazolin-4-yl]amino]phenol Chemical class C1=CC(O)=CC=C1NC1=NC(C=2OC(=CC=2)[N+]([O-])=O)=NC2=CC=CC=C12 DAVMWQFOFAMOCP-UHFFFAOYSA-N 0.000 description 2
- 241000283690 Bos taurus Species 0.000 description 2
- 241000191967 Staphylococcus aureus Species 0.000 description 2
- 238000006243 chemical reaction Methods 0.000 description 2
- 239000012043 crude product Substances 0.000 description 2
- 239000013078 crystal Substances 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 244000005700 microbiome Species 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- CDAWCLOXVUBKRW-UHFFFAOYSA-N 2-aminophenol Chemical compound NC1=CC=CC=C1O CDAWCLOXVUBKRW-UHFFFAOYSA-N 0.000 description 1
- CWLKGDAVCFYWJK-UHFFFAOYSA-N 3-aminophenol Chemical compound NC1=CC=CC(O)=C1 CWLKGDAVCFYWJK-UHFFFAOYSA-N 0.000 description 1
- 208000035143 Bacterial infection Diseases 0.000 description 1
- 206010008631 Cholera Diseases 0.000 description 1
- 206010010741 Conjunctivitis Diseases 0.000 description 1
- 208000004232 Enteritis Diseases 0.000 description 1
- 241000588724 Escherichia coli Species 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 241000588622 Moraxella bovis Species 0.000 description 1
- 241000606856 Pasteurella multocida Species 0.000 description 1
- 241000293869 Salmonella enterica subsp. enterica serovar Typhimurium Species 0.000 description 1
- 241000193985 Streptococcus agalactiae Species 0.000 description 1
- 239000003242 anti bacterial agent Substances 0.000 description 1
- 208000022362 bacterial infectious disease Diseases 0.000 description 1
- 244000309466 calf Species 0.000 description 1
- 239000003937 drug carrier Substances 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 230000008029 eradication Effects 0.000 description 1
- 239000000499 gel Substances 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 230000002458 infectious effect Effects 0.000 description 1
- 231100000518 lethal Toxicity 0.000 description 1
- 230000001665 lethal effect Effects 0.000 description 1
- 208000004396 mastitis Diseases 0.000 description 1
- 238000002844 melting Methods 0.000 description 1
- 230000008018 melting Effects 0.000 description 1
- 239000002674 ointment Substances 0.000 description 1
- 229940051027 pasteurella multocida Drugs 0.000 description 1
- 244000052769 pathogen Species 0.000 description 1
- 239000000546 pharmaceutical excipient Substances 0.000 description 1
- 239000000376 reactant Substances 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US71927268A | 1968-04-05 | 1968-04-05 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO122373B true NO122373B (ja) | 1971-06-21 |
Family
ID=24889428
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO0247/69A NO122373B (ja) | 1968-04-05 | 1969-01-22 |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US3542784A (ja) |
| AT (1) | AT284829B (ja) |
| BE (1) | BE729298A (ja) |
| CH (1) | CH507979A (ja) |
| DE (1) | DE1909522A1 (ja) |
| DK (1) | DK117566B (ja) |
| ES (1) | ES363881A1 (ja) |
| FR (1) | FR2005591A1 (ja) |
| GB (1) | GB1168430A (ja) |
| IE (1) | IE32904B1 (ja) |
| IL (1) | IL31322A (ja) |
| NL (1) | NL6904849A (ja) |
| NO (1) | NO122373B (ja) |
| SE (1) | SE357367B (ja) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2232532A1 (de) * | 1972-07-03 | 1974-01-31 | Hoechst Ag | Bis-n-heterocyclische verbindungen mit chemotherapeutischen eigenschaften und verfahren zu ihrer herstellung |
| US3974277A (en) * | 1974-09-06 | 1976-08-10 | Diamond Shamrock Corporation | 2-[2-(5-Nitro-2-furyl)vinyl]-4-(anilino)quinazolines as growth promotants and feed efficiency enhancing agents |
| US3970648A (en) * | 1974-09-06 | 1976-07-20 | Diamond Shamrock Corporation | 2-[2-(5-Nitro-2-furyl)vinyl]-4-(anilino)quinazolines |
| US3973021A (en) * | 1974-09-06 | 1976-08-03 | Diamond Shamrock Corporation | 2-[2-(5-Nitro-2-furyl)vinyl]-4-(phydroxyanilino)quinazoline as a bactericide |
| AU7831398A (en) * | 1997-06-10 | 1998-12-30 | E.I. Du Pont De Nemours And Company | Pyrimidinyl azole herbicides |
| US20080146562A1 (en) * | 2003-08-08 | 2008-06-19 | Ulysses Pharmaceutical Products Inc., | Halogenated quinazolinyl nitrofurans as antibacterial agents |
| AU2004262533A1 (en) * | 2003-08-08 | 2005-02-17 | Ulysses Pharmaceutical Products Inc. | Halogenated quinazolinyl nitrofurans as antibacterial agents |
| MX2007003374A (es) * | 2004-09-23 | 2007-06-05 | Ulysses Pharmaceutical Products Inc | Antibioticos carbociclicos y heterociclicos y uso de los mismos. |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3238208A (en) * | 1962-02-27 | 1966-03-01 | Burroughs Wellcome Co | Certain 5-anilinouracils |
| US3324122A (en) * | 1964-12-14 | 1967-06-06 | Norwich Pharma Co | Series of 4-substituted-2-(5-nitro-2-furyl) quinazolines |
-
1968
- 1968-04-05 US US719272A patent/US3542784A/en not_active Expired - Lifetime
- 1968-12-25 IL IL31322A patent/IL31322A/en unknown
-
1969
- 1969-01-16 SE SE00527/69A patent/SE357367B/xx unknown
- 1969-01-22 NO NO0247/69A patent/NO122373B/no unknown
- 1969-01-28 GB GB4748/69A patent/GB1168430A/en not_active Expired
- 1969-01-30 IE IE125/69A patent/IE32904B1/xx unknown
- 1969-02-19 DK DK91169AA patent/DK117566B/da unknown
- 1969-02-20 ES ES363881A patent/ES363881A1/es not_active Expired
- 1969-03-03 BE BE729298D patent/BE729298A/xx unknown
- 1969-03-25 FR FR6908696A patent/FR2005591A1/fr not_active Withdrawn
- 1969-03-27 CH CH463869A patent/CH507979A/de not_active IP Right Cessation
- 1969-03-28 NL NL6904849A patent/NL6904849A/xx unknown
- 1969-04-04 AT AT335169A patent/AT284829B/de not_active IP Right Cessation
- 1969-06-18 DE DE19691909522 patent/DE1909522A1/de active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| DK117566B (da) | 1970-05-11 |
| US3542784A (en) | 1970-11-24 |
| IE32904L (en) | 1969-10-05 |
| IL31322A (en) | 1972-05-30 |
| AT284829B (de) | 1970-09-25 |
| GB1168430A (en) | 1969-10-22 |
| CH507979A (de) | 1971-05-31 |
| IE32904B1 (en) | 1974-01-09 |
| DE1909522A1 (de) | 1969-10-30 |
| IL31322A0 (en) | 1969-02-27 |
| SE357367B (ja) | 1973-06-25 |
| BE729298A (ja) | 1969-09-03 |
| NL6904849A (ja) | 1969-10-07 |
| ES363881A1 (es) | 1971-01-01 |
| FR2005591A1 (ja) | 1969-12-12 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| FI56531C (fi) | Foerfarande foer framstaellning av isotiocyanobenstiazoler med anthelmintisk och mikrobicid verkan | |
| JPS62161728A (ja) | 抗菌剤 | |
| NO311521B1 (no) | Eventuelt substituerte 8-cyan-1-cyklopropyl-7-(2,8- diazabicyklo-[4.3.0]-nonan-8-yl)-6-fluor-1,4-dihydro-4-okso-3-kinolinkarboksylsyrer og deres derivater, fremgangsmåte forfremstilling derav, anvendelse av forbindelsene samt legemiddelinnehold | |
| Aminkhani et al. | Highly Efficient One‐Pot Three‐Component Synthesis and Antimicrobial Activity of 2‐Amino‐4H‐chromene Derivatives | |
| NO122373B (ja) | ||
| Fareed et al. | Synthesis, spectroscopic characterization and pharmacological evaluation of oxazolone derivatives | |
| US3625987A (en) | Cyano carbamoyloximes | |
| US3457294A (en) | N-(substituted-benzoyl) aminoaceto- and aminopropionitriles | |
| CN113754595A (zh) | 一类含二硫醚结构的6-氟喹唑啉类衍生物的制备方法及其应用 | |
| CN106692138A (zh) | N-苄基咪酰胺衍生物作为多粘菌素类抗生素协同增效剂的应用 | |
| RU2428419C2 (ru) | Новые бензофуроксаны, обладающие фунгицидной и бактерицидной активностью | |
| US3407195A (en) | 4-methyl-1-(5-nitrofurfurylideneamino)-2-imidazolidinone | |
| CN102180809B (zh) | 截短侧耳素的水杨酰胺醚化合物及其制备方法 | |
| EP0863132B1 (en) | Ketonitrile derivatives and antibacterial agent and drug containing the same | |
| US3479343A (en) | Novel carbazates | |
| US3142616A (en) | Controlling microorganisms employing sulfonylacetonitriles | |
| Mohammed | Synthesis, characterization, and antibacterial activity of chalcones derivatives | |
| RU2717243C2 (ru) | 3-Бромо-4-(4-метоксифенил)-N-(5-метил-1,3,4-тиадиазол-2-ил)-2,4-диоксобутанамид, обладающий антимикробным действием | |
| CN114621214B (zh) | 一种抗菌席夫碱n-酰化物及其制备方法和应用 | |
| CN114671865B (zh) | 一种含噻唑-吡啶烷基季铵盐侧链的截短侧耳素衍生物及其制备方法与应用 | |
| RU2768759C1 (ru) | Метиловый эфир 2-{ 3-[2-(9н-флуорен-9-илиден)гидразоно]-5-фенил2-2фуранилиден} уксусной кислоты, обладающий противомикробной активностью | |
| CN116730947B (zh) | 2,4,5-三取代噻唑类化合物及其制备方法和应用 | |
| RU2809052C1 (ru) | Применение (z)-1,2-ди([1,1':3',1''-терфенил]-5'-ил)диазен-1-оксида в качестве антибактериального средства в отношении грамположительных микроорганизмов | |
| RU2671573C1 (ru) | 2-[6-метил-4-(тиетан-3-илокси)пиримидин-2-илтио]ацетогидразид малеиновой кислоты, проявляющий противомикробную активность | |
| US3159654A (en) | New series of carboxylic acid esters of 5-nitro-2-furyl alkylidene hydroxyalkyl semicbazones |