NO117370B - - Google Patents

Download PDF

Info

Publication number
NO117370B
NO117370B NO150841A NO15084163A NO117370B NO 117370 B NO117370 B NO 117370B NO 150841 A NO150841 A NO 150841A NO 15084163 A NO15084163 A NO 15084163A NO 117370 B NO117370 B NO 117370B
Authority
NO
Norway
Prior art keywords
lower alkyl
acid
dichloro
mol
compound
Prior art date
Application number
NO150841A
Other languages
English (en)
Norwegian (no)
Inventor
E Schultz
J Sprague
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of NO117370B publication Critical patent/NO117370B/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/095—Sulfur, selenium, or tellurium compounds, e.g. thiols
    • A61K31/10—Sulfides; Sulfoxides; Sulfones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C323/24—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/25—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C327/00—Thiocarboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C07C45/46—Friedel-Crafts reactions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • C07C59/66—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
    • C07C59/68—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring
    • C07C59/70—Ethers of hydroxy-acetic acid, e.g. substitutes on the ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/76—Unsaturated compounds containing keto groups
    • C07C59/90—Unsaturated compounds containing keto groups containing singly bound oxygen-containing groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/006—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length of peptides containing derivatised side chain amino acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Stereoscopic And Panoramic Photography (AREA)
NO150841A 1962-11-19 1963-11-15 NO117370B (en:Method)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US23871462A 1962-11-19 1962-11-19

Publications (1)

Publication Number Publication Date
NO117370B true NO117370B (en:Method) 1969-08-04

Family

ID=22899024

Family Applications (1)

Application Number Title Priority Date Filing Date
NO150841A NO117370B (en:Method) 1962-11-19 1963-11-15

Country Status (10)

Country Link
AT (1) AT254175B (en:Method)
BE (1) BE640050A (en:Method)
BR (1) BR6354614D0 (en:Method)
CH (1) CH481897A (en:Method)
DE (2) DE1493973A1 (en:Method)
FI (1) FI42571B (en:Method)
FR (3) FR1583602A (en:Method)
GB (1) GB1068035A (en:Method)
NL (1) NL137820C (en:Method)
NO (1) NO117370B (en:Method)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2704224B1 (fr) * 1993-04-20 1995-08-25 Adir Nouveaux acides et esters phénoxy isobutyriques substitués.

Also Published As

Publication number Publication date
FI42571B (en:Method) 1970-06-01
FR3728M (fr) 1965-12-06
DE345734C (en:Method)
CH481897A (de) 1969-11-30
GB1068035A (en) 1967-05-10
DE1493973A1 (de) 1969-12-11
AT254175B (de) 1967-05-10
BE640050A (fr) 1964-05-18
BR6354614D0 (pt) 1973-07-12
FR1583602A (en:Method) 1969-11-21
NL137820C (en:Method) 1973-05-16
FR95106E (fr) 1970-07-24

Similar Documents

Publication Publication Date Title
EP0415850B1 (fr) Sels de métaux bivalents de l'acide N, N-di(carboxyméthyl)amino-2 cyano-3 carboxyméthyl-4 carboxy-5 thiophène,leur procédé de préparation et les compositions pharmaceutiques les renfermant
US3781328A (en) Phenoxy-alkyl-carboxylic acid compounds
US3784697A (en) Pharmaceutical composition containing phenoxyalkane-carboxylic acids,salts and esters thereof
US6323240B1 (en) 4-phenyl-4-oxo-butanoic acid derivatives with kynurenine-3-hydroxylase inhibiting activity
NO125672B (en:Method)
NO152148B (no) Vaapensystem med sylindermekanisme
EP0061386B1 (fr) Acides ((2-oxo-3-tétrahydrothiénylcarbamoyl)-alkylthio) acétiques, leurs sels et leurs esters, leur procédé de préparation et les compositions pharmaceutiques en contenant
US3383411A (en) 4-alkanoylphenoxy-alkanoic acids
KR101069276B1 (ko) 대사 질환의 치료용 화합물
NO155168B (no) Galvanisk element, spesielt metall-luft-celle.
NZ260350A (en) Phenoxyisobutyric acid derivatives, preparation and pharmaceutical compositions thereof
IE46699B1 (en) 11,12-secoprostaglandins
DE69414194T2 (de) Aminosäurederivate und ihre Verwendung als Enkephalinase-Inhibitoren
US3453312A (en) (beta - (substituted-thio) - acylphenoxy)-alkanoic acids and (beta-(substitutedthio) acylphenylmercapto) alkanoic acids and derivatives thereof
US2863753A (en) Method of weed control
DK160760B (da) Analogifremgangsmaade til fremstilling af n-naphthoylglycinderivater
US4594443A (en) Derivatives of 4-phenyl-4-oxo-buten-2-oic acid and therapeutic use thereof
US3255242A (en) (alpha-alkylideneacyl)naphthyloxy monocarboxylic acids
Barnish et al. Promotion of carbohydrate oxidation in the heart by some phenylglyoxylic acids
US3398188A (en) And [4-(2-haloalkanoyl) phenylmercapto]-alkanoic acids
CA2105683C (en) N-¬¬4,5-dihydroxy-and 4,5,8-trihydroxy-9,10-dihydro-9, 10-dioxo-2-anthracene-yl|carbonyl|amino acids useful in the therapy of osteoarticular affections
US4473583A (en) Compositions containing certain derivatives of 4-phenyl-4-oxobuten-2-oic acid and methods of treatment using them
EP1583738A1 (en) Indenoncarboxylic acids derivatives and their use for the treatment of and preventing diabetes and dyslipidaemia
US3419606A (en) 4-(2-methylenealkanoyl)phenylsulfinyl alkanoic acids
US3250804A (en) (alpha-alkylideneacyl)phenoxy-and phenylthio-methanesulfonic acids