NO116683B - - Google Patents
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- Publication number
- NO116683B NO116683B NO15641865A NO15641865A NO116683B NO 116683 B NO116683 B NO 116683B NO 15641865 A NO15641865 A NO 15641865A NO 15641865 A NO15641865 A NO 15641865A NO 116683 B NO116683 B NO 116683B
- Authority
- NO
- Norway
- Prior art keywords
- calcium
- solution
- salt
- complex
- gluconate
- Prior art date
Links
- 239000000243 solution Substances 0.000 claims description 37
- 239000011575 calcium Substances 0.000 claims description 35
- 229910052791 calcium Inorganic materials 0.000 claims description 32
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 claims description 31
- 229960005069 calcium Drugs 0.000 claims description 31
- 159000000007 calcium salts Chemical class 0.000 claims description 14
- 239000004227 calcium gluconate Substances 0.000 claims description 13
- 229960004494 calcium gluconate Drugs 0.000 claims description 13
- 235000013927 calcium gluconate Nutrition 0.000 claims description 13
- NEEHYRZPVYRGPP-UHFFFAOYSA-L calcium;2,3,4,5,6-pentahydroxyhexanoate Chemical compound [Ca+2].OCC(O)C(O)C(O)C(O)C([O-])=O.OCC(O)C(O)C(O)C(O)C([O-])=O NEEHYRZPVYRGPP-UHFFFAOYSA-L 0.000 claims description 13
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 12
- 238000002347 injection Methods 0.000 claims description 10
- 239000007924 injection Substances 0.000 claims description 10
- 150000003839 salts Chemical class 0.000 claims description 10
- CBOCVOKPQGJKKJ-UHFFFAOYSA-L Calcium formate Chemical compound [Ca+2].[O-]C=O.[O-]C=O CBOCVOKPQGJKKJ-UHFFFAOYSA-L 0.000 claims description 9
- 229940044172 calcium formate Drugs 0.000 claims description 9
- 239000004281 calcium formate Substances 0.000 claims description 9
- 235000019255 calcium formate Nutrition 0.000 claims description 9
- MKJXYGKVIBWPFZ-UHFFFAOYSA-L calcium lactate Chemical compound [Ca+2].CC(O)C([O-])=O.CC(O)C([O-])=O MKJXYGKVIBWPFZ-UHFFFAOYSA-L 0.000 claims description 8
- 239000001527 calcium lactate Substances 0.000 claims description 8
- 229960002401 calcium lactate Drugs 0.000 claims description 8
- 235000011086 calcium lactate Nutrition 0.000 claims description 8
- 241001465754 Metazoa Species 0.000 claims description 5
- 238000009835 boiling Methods 0.000 claims description 3
- 238000001816 cooling Methods 0.000 claims description 3
- 238000004519 manufacturing process Methods 0.000 claims description 3
- 239000013543 active substance Substances 0.000 claims description 2
- 239000007864 aqueous solution Substances 0.000 claims description 2
- UXVMQQNJUSDDNG-UHFFFAOYSA-L Calcium chloride Chemical compound [Cl-].[Cl-].[Ca+2] UXVMQQNJUSDDNG-UHFFFAOYSA-L 0.000 description 4
- 239000001110 calcium chloride Substances 0.000 description 4
- 229910001628 calcium chloride Inorganic materials 0.000 description 4
- 238000000034 method Methods 0.000 description 3
- 239000011574 phosphorus Substances 0.000 description 3
- 229910052698 phosphorus Inorganic materials 0.000 description 3
- RGHNJXZEOKUKBD-SQOUGZDYSA-N D-gluconic acid Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O RGHNJXZEOKUKBD-SQOUGZDYSA-N 0.000 description 2
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 description 2
- 241000282849 Ruminantia Species 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 239000012153 distilled water Substances 0.000 description 2
- 231100000086 high toxicity Toxicity 0.000 description 2
- 230000000622 irritating effect Effects 0.000 description 2
- 230000035939 shock Effects 0.000 description 2
- CYDQOEWLBCCFJZ-UHFFFAOYSA-N 4-(4-fluorophenyl)oxane-4-carboxylic acid Chemical compound C=1C=C(F)C=CC=1C1(C(=O)O)CCOCC1 CYDQOEWLBCCFJZ-UHFFFAOYSA-N 0.000 description 1
- 206010033799 Paralysis Diseases 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- KGBXLFKZBHKPEV-UHFFFAOYSA-N boric acid Chemical compound OB(O)O KGBXLFKZBHKPEV-UHFFFAOYSA-N 0.000 description 1
- 239000004327 boric acid Substances 0.000 description 1
- LUULGDQBMOTIRA-QANWPUCUSA-L calcium (3R,5R)-1,3,4,5-tetrahydroxycyclohexane-1-carboxylate Chemical compound [Ca++].O[C@@H]1CC(O)(C[C@@H](O)C1O)C([O-])=O.O[C@@H]1CC(O)(C[C@@H](O)C1O)C([O-])=O LUULGDQBMOTIRA-QANWPUCUSA-L 0.000 description 1
- 229940043430 calcium compound Drugs 0.000 description 1
- 150000001674 calcium compounds Chemical class 0.000 description 1
- 235000013921 calcium diglutamate Nutrition 0.000 description 1
- FATUQANACHZLRT-XBQZYUPDSA-L calcium;(2r,3r,4s,5r,6r)-2,3,4,5,6,7-hexahydroxyheptanoate Chemical compound [Ca+2].OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)[C@@H](O)C([O-])=O.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)[C@@H](O)C([O-])=O FATUQANACHZLRT-XBQZYUPDSA-L 0.000 description 1
- UMVAYAXXQSFULN-QHTZZOMLSA-L calcium;(2s)-2-aminopentanedioate;hydron Chemical compound [Ca+2].[O-]C(=O)[C@@H](N)CCC(O)=O.[O-]C(=O)[C@@H](N)CCC(O)=O UMVAYAXXQSFULN-QHTZZOMLSA-L 0.000 description 1
- VPWAVWZPVGDNMN-UHFFFAOYSA-L calcium;2,3-dihydroxypropanoate Chemical compound [Ca+2].OCC(O)C([O-])=O.OCC(O)C([O-])=O VPWAVWZPVGDNMN-UHFFFAOYSA-L 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- HCAJEUSONLESMK-UHFFFAOYSA-N cyclohexylsulfamic acid Chemical compound OS(=O)(=O)NC1CCCCC1 HCAJEUSONLESMK-UHFFFAOYSA-N 0.000 description 1
- 230000006735 deficit Effects 0.000 description 1
- 239000012535 impurity Substances 0.000 description 1
- 238000010253 intravenous injection Methods 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 159000000003 magnesium salts Chemical class 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 150000002762 monocarboxylic acid derivatives Chemical class 0.000 description 1
- 210000005036 nerve Anatomy 0.000 description 1
- 150000007524 organic acids Chemical class 0.000 description 1
- 235000005985 organic acids Nutrition 0.000 description 1
- ACVYVLVWPXVTIT-UHFFFAOYSA-M phosphinate Chemical compound [O-][PH2]=O ACVYVLVWPXVTIT-UHFFFAOYSA-M 0.000 description 1
- -1 phosphorus compound Chemical class 0.000 description 1
- 239000002510 pyrogen Substances 0.000 description 1
- 239000001540 sodium lactate Substances 0.000 description 1
- 235000011088 sodium lactate Nutrition 0.000 description 1
- 229940005581 sodium lactate Drugs 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/42—Phosphorus; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Inorganic Chemistry (AREA)
- Dermatology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE67864 | 1964-01-20 | ||
| SE15389/64A SE330063B (enrdf_load_stackoverflow) | 1964-12-18 | 1964-12-18 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO116683B true NO116683B (enrdf_load_stackoverflow) | 1969-05-05 |
Family
ID=26654174
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO15641865A NO116683B (enrdf_load_stackoverflow) | 1964-01-20 | 1965-01-19 |
Country Status (6)
| Country | Link |
|---|---|
| DE (1) | DE1287254B (enrdf_load_stackoverflow) |
| DK (1) | DK112268B (enrdf_load_stackoverflow) |
| FI (1) | FI42856C (enrdf_load_stackoverflow) |
| GB (1) | GB1053912A (enrdf_load_stackoverflow) |
| NL (1) | NL152453B (enrdf_load_stackoverflow) |
| NO (1) | NO116683B (enrdf_load_stackoverflow) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2158730C3 (de) * | 1971-11-26 | 1982-05-06 | Centrala Industriala de Medicamente si Coloranti, Bucuresti | Verfahren zur Herstellung eines Calciumsalzes mit hoher Löslichkeit |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE594752C (de) * | 1931-12-30 | 1934-03-22 | Chem Fab Vormals Sandoz | Verfahren zur Herstellung von wasserloeslichen organischen Calciumdoppelverbindungen |
| DE688962C (de) * | 1937-12-10 | 1940-03-07 | Johann A Wuelfing Chem Fab | Verfahren zur Herstellung von haltbaren Calciumsalzloesungen |
| DE726635C (de) * | 1938-11-23 | 1942-10-17 | Ig Farbenindustrie Ag | Verfahren zur Herstellung gehaltreicher, haltbarer Loesungen von Calciumgluconat oder -lactat |
-
0
- GB GB1053912D patent/GB1053912A/en active Active
-
1964
- 1964-12-30 FI FI278164A patent/FI42856C/fi active
-
1965
- 1965-01-14 DK DK17965A patent/DK112268B/da unknown
- 1965-01-18 NL NL6500586A patent/NL152453B/xx not_active IP Right Cessation
- 1965-01-19 DE DE1965A0048149 patent/DE1287254B/de active Pending
- 1965-01-19 NO NO15641865A patent/NO116683B/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE1287254B (de) | 1969-01-16 |
| GB1053912A (enrdf_load_stackoverflow) | |
| FI42856B (enrdf_load_stackoverflow) | 1970-08-03 |
| NL6500586A (enrdf_load_stackoverflow) | 1965-07-21 |
| NL152453B (nl) | 1977-03-15 |
| FI42856C (fi) | 1970-11-10 |
| DK112268B (da) | 1968-11-25 |
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