NL9500216A - Farmaceutische samenstelling voor de behandeling van herpes. - Google Patents

Farmaceutische samenstelling voor de behandeling van herpes. Download PDF

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Publication number
NL9500216A
NL9500216A NL9500216A NL9500216A NL9500216A NL 9500216 A NL9500216 A NL 9500216A NL 9500216 A NL9500216 A NL 9500216A NL 9500216 A NL9500216 A NL 9500216A NL 9500216 A NL9500216 A NL 9500216A
Authority
NL
Netherlands
Prior art keywords
pharmaceutical composition
component
composition according
cetrimide
activity
Prior art date
Application number
NL9500216A
Other languages
English (en)
Dutch (nl)
Inventor
Dirk Andre Richard Van Berghe
Original Assignee
Bio Pharma Sciences Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bio Pharma Sciences Bv filed Critical Bio Pharma Sciences Bv
Priority to NL9500216A priority Critical patent/NL9500216A/nl
Priority to CN96191807A priority patent/CN1121232C/zh
Priority to US08/875,661 priority patent/US6284289B1/en
Priority to JP8524159A priority patent/JPH10513193A/ja
Priority to DE69624340T priority patent/DE69624340T2/de
Priority to ES96902505T priority patent/ES2185760T3/es
Priority to AT96902505T priority patent/ATE226081T1/de
Priority to DK96902505T priority patent/DK0808168T3/da
Priority to EP96902505A priority patent/EP0808168B1/en
Priority to PCT/NL1996/000038 priority patent/WO1996024367A1/en
Priority to CA002211802A priority patent/CA2211802C/en
Priority to AU46788/96A priority patent/AU712744B2/en
Publication of NL9500216A publication Critical patent/NL9500216A/nl
Priority to JP2007319836A priority patent/JP2008074872A/ja

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/13Coniferophyta (gymnosperms)
    • A61K36/14Cupressaceae (Cypress family), e.g. juniper or cypress
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/26Aristolochiaceae (Birthwort family), e.g. heartleaf
    • A61K36/264Aristolochia (Dutchman's pipe)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/30Boraginaceae (Borage family), e.g. comfrey, lungwort or forget-me-not
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/36Caryophyllaceae (Pink family), e.g. babysbreath or soapwort
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/38Clusiaceae, Hypericaceae or Guttiferae (Hypericum or Mangosteen family), e.g. common St. Johnswort
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/482Cassia, e.g. golden shower tree
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/49Fagaceae (Beech family), e.g. oak or chestnut
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/52Juglandaceae (Walnut family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/534Mentha (mint)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/537Salvia (sage)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/61Myrtaceae (Myrtle family), e.g. teatree or eucalyptus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/736Prunus, e.g. plum, cherry, peach, apricot or almond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/77Sapindaceae (Soapberry family), e.g. lychee or soapberry
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/81Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/86Violaceae (Violet family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/886Aloeaceae (Aloe family), e.g. aloe vera
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/90Smilacaceae (Catbrier family), e.g. greenbrier or sarsaparilla
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • A61P31/22Antivirals for DNA viruses for herpes viruses

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicinal Preparation (AREA)
NL9500216A 1995-02-06 1995-02-06 Farmaceutische samenstelling voor de behandeling van herpes. NL9500216A (nl)

Priority Applications (13)

Application Number Priority Date Filing Date Title
NL9500216A NL9500216A (nl) 1995-02-06 1995-02-06 Farmaceutische samenstelling voor de behandeling van herpes.
ES96902505T ES2185760T3 (es) 1995-02-06 1996-01-23 Composicion farmaceutica para el tratamiento del herpes.
US08/875,661 US6284289B1 (en) 1995-02-06 1996-01-23 Treatment of herpes infection with composition containing quaternary ammonium compound and an anti-viral agent
JP8524159A JPH10513193A (ja) 1995-02-06 1996-01-23 ヘルペスを処置するための医薬組成物
DE69624340T DE69624340T2 (de) 1995-02-06 1996-01-23 Pharmazeutische zusammensetzung zur behandlung von herpes
CN96191807A CN1121232C (zh) 1995-02-06 1996-01-23 治疗疱疹的药物组合物
AT96902505T ATE226081T1 (de) 1995-02-06 1996-01-23 Pharmazeutische zusammensetzung zur behandlung von herpes
DK96902505T DK0808168T3 (da) 1995-02-06 1996-01-23 Farmaceutisk præparat til behandlingen af herpes
EP96902505A EP0808168B1 (en) 1995-02-06 1996-01-23 Pharmaceutical composition for the treatment of herpes
PCT/NL1996/000038 WO1996024367A1 (en) 1995-02-06 1996-01-23 Pharmaceutical composition for the treatment of herpes
CA002211802A CA2211802C (en) 1995-02-06 1996-01-23 Pharmaceutical composition for the treatment of herpes
AU46788/96A AU712744B2 (en) 1995-02-06 1996-01-23 Pharmaceutical composition for the treatment of herpes
JP2007319836A JP2008074872A (ja) 1995-02-06 2007-12-11 ヘルペスを処置するための医薬組成物

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NL9500216A NL9500216A (nl) 1995-02-06 1995-02-06 Farmaceutische samenstelling voor de behandeling van herpes.
NL9500216 1995-02-06

Publications (1)

Publication Number Publication Date
NL9500216A true NL9500216A (nl) 1996-09-02

Family

ID=19865548

Family Applications (1)

Application Number Title Priority Date Filing Date
NL9500216A NL9500216A (nl) 1995-02-06 1995-02-06 Farmaceutische samenstelling voor de behandeling van herpes.

Country Status (12)

Country Link
US (1) US6284289B1 (zh)
EP (1) EP0808168B1 (zh)
JP (2) JPH10513193A (zh)
CN (1) CN1121232C (zh)
AT (1) ATE226081T1 (zh)
AU (1) AU712744B2 (zh)
CA (1) CA2211802C (zh)
DE (1) DE69624340T2 (zh)
DK (1) DK0808168T3 (zh)
ES (1) ES2185760T3 (zh)
NL (1) NL9500216A (zh)
WO (1) WO1996024367A1 (zh)

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US6348503B1 (en) 1996-02-12 2002-02-19 Meryl J. Squires Method and topical treatment composition for herpesvirus hominis
US6355684B1 (en) 1990-10-11 2002-03-12 Meryl J. Squires Antimicrobial treatment for herpes simplex virus and other infectious diseases
US6350784B1 (en) 1996-02-12 2002-02-26 Meryl J. Squires Antimicrobial prevention and treatment of human immunedeficiency virus and other infectious diseases
US8267982B2 (en) * 1998-08-25 2012-09-18 Advanced Photodynamic Technologies, Inc. Photodynamic cellular and acellular organism eradication utilizing a photosensitive material and surfactant
US8173709B2 (en) 1999-09-22 2012-05-08 Quadex Pharmaceuticals, Llc Anti-infective methods for treating pathogen-induced disordered tissues
GB2375113B (en) * 2000-01-21 2004-10-20 Biovex Ltd A modified, oncolytic, non-laboratory HSV strain and its use in treating cancer
GB0317511D0 (en) * 2003-07-25 2003-08-27 Biovex Ltd Viral vectors
ITMI20032287A1 (it) * 2003-11-24 2005-05-25 Indena Spa Composizioni per il trattamento delle affezioni del cavo orale e delle prime vie respiratorie
US7968122B2 (en) * 2003-12-10 2011-06-28 Adventrx Pharmaceuticals, Inc. Anti-viral pharmaceutical compositions
US7250180B2 (en) * 2004-01-07 2007-07-31 Edwin Cevallos Arellano Anti-prostate cancer composition and therapeutic uses therefor
CN100427082C (zh) * 2005-08-02 2008-10-22 盛华(广州)医药科技有限公司 羟基苯甲酸酯及其类似物在制备预防和治疗病毒性感染药物中的应用
US8044098B2 (en) 2005-08-02 2011-10-25 Shenghua Guangzhou Pharmaceutical Science & Technology Co., Ltd. Use of hydroxybenzoic acids and their esters and analogues for preventing or treating virus infection
US7790203B2 (en) * 2005-12-13 2010-09-07 Lowder Tom R Composition and regimen for the treatment of herpes simplex virus, herpes zoster, and herpes genitalia epidermal herpetic lesions
AU2010330812B2 (en) * 2009-12-18 2016-03-10 Exodos Life Sciences Limited Partnership Methods and compositions for treating inflammation of skin
US8247006B2 (en) * 2010-06-22 2012-08-21 Golio Dominick I Composition and method of treating lipid encapsulated virus infections
PT2563374E (pt) 2010-07-08 2014-01-23 Devirex Ag Composições de polietileno glicol para o controlo da reincidência de herpes labial, herpes genital, e herpes zóster
US8846725B2 (en) 2011-01-24 2014-09-30 Quadex Pharmaceuticals, Llc Highly penetrating compositions and methods for treating pathogen-induced disordered tissues
WO2014055659A1 (en) * 2012-10-03 2014-04-10 Pharma Green Llc Methods and compositions for production of recombinant pharmaceutical proteins in medicinal plants
US9463180B2 (en) 2013-03-14 2016-10-11 Quadex Pharmaceuticals, Llc Treatment of molluscum contagiosum
US9125911B2 (en) 2013-03-14 2015-09-08 Quadex Pharmaceuticals, Llc Combined systemic and topical treatment of disordered tissues
US9549930B2 (en) 2013-03-14 2017-01-24 Quadex Pharmaceuticals, Llc Combined systemic and topical treatment of disordered and/or prodromal stage tissue
ITUB20152286A1 (it) * 2015-07-17 2017-01-17 Harven S A S Composizione anti herpes
US10744175B2 (en) * 2016-02-23 2020-08-18 Apurve Mehra Herbal composition for the treatment of Herpes

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Title
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J.A. SANDS: "virucidal activity of cetyltrimethylammonium bromide below the critical micelle concentration.", FEMS MICROBIOL. LETT., vol. 36, no. 2-3, pages 261 - 263 *
M. AMOROS ET AL.: "Effect of saponins from Anagallis arvensis on experimental herpes simplex keratitis in rabbits.", PLANTA MED., vol. 54, no. 2, pages 128 - 131 *
M. KUROKAWA ET AL.: "Efficacy of traditional herbal medicines in combination with acyclovir against herpes simplex virus type 1 infection in vitro and in vivo.", ANTIVIR. RES., vol. 27, no. 1-2, pages 19 - 37 *

Also Published As

Publication number Publication date
EP0808168B1 (en) 2002-10-16
DK0808168T3 (da) 2003-02-17
CA2211802A1 (en) 1996-08-15
WO1996024367A1 (en) 1996-08-15
AU4678896A (en) 1996-08-27
CN1121232C (zh) 2003-09-17
DE69624340D1 (de) 2002-11-21
EP0808168A1 (en) 1997-11-26
US6284289B1 (en) 2001-09-04
JP2008074872A (ja) 2008-04-03
ES2185760T3 (es) 2003-05-01
AU712744B2 (en) 1999-11-18
ATE226081T1 (de) 2002-11-15
CA2211802C (en) 2009-06-02
CN1173820A (zh) 1998-02-18
DE69624340T2 (de) 2003-06-18
JPH10513193A (ja) 1998-12-15

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