NL8700842A - - Google Patents

Info

Publication number
NL8700842A
NL8700842A NL8700842A NL8700842A NL8700842A NL 8700842 A NL8700842 A NL 8700842A NL 8700842 A NL8700842 A NL 8700842A NL 8700842 A NL8700842 A NL 8700842A NL 8700842 A NL8700842 A NL 8700842A
Authority
NL
Netherlands
Application number
NL8700842A
Original Assignee
Duphar Int Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Duphar Int Res filed Critical Duphar Int Res
Priority to NL8700842A priority Critical patent/NL8700842A/xx
Priority to ZA882385A priority patent/ZA882385B/xx
Priority to JP63082373A priority patent/JPS63290848A/ja
Priority to EP88200648A priority patent/EP0289070A1/en
Priority to IL85996A priority patent/IL85996A/xx
Priority to DK187288A priority patent/DK187288A/da
Priority to NZ224170A priority patent/NZ224170A/en
Priority to AU14344/88A priority patent/AU611141B2/en
Publication of NL8700842A publication Critical patent/NL8700842A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Addiction (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Furan Compounds (AREA)
  • Pyrrole Compounds (AREA)
NL8700842A 1987-04-10 1987-04-10 NL8700842A (sh)

Priority Applications (8)

Application Number Priority Date Filing Date Title
NL8700842A NL8700842A (sh) 1987-04-10 1987-04-10
ZA882385A ZA882385B (en) 1987-04-10 1988-04-05 Tertiary arylethyl amine derivatives having opiate-antagonistic activity
JP63082373A JPS63290848A (ja) 1987-04-10 1988-04-05 アヘン誘導体−拮抗活性を有する第三アリールエチルアミン誘導体
EP88200648A EP0289070A1 (en) 1987-04-10 1988-04-06 Tertiary arylethyl amine derivatives having opiate-antagonistic activity
IL85996A IL85996A (en) 1987-04-10 1988-04-06 Tertiary arylethyl amine derivatives,their preparation and pharmaceutical compositions containing them
DK187288A DK187288A (da) 1987-04-10 1988-04-06 Tertiaere arylethylaminderivater med opiatantagonistisk virkning
NZ224170A NZ224170A (en) 1987-04-10 1988-04-07 Tertiary arylethyl amine derivatives having opiate-antagonistic activity and their pharmaceutical compositions
AU14344/88A AU611141B2 (en) 1987-04-10 1988-04-07 Tertiary arylethyl amine derivatives having opiate-antagonistic activity

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL8700842A NL8700842A (sh) 1987-04-10 1987-04-10

Publications (1)

Publication Number Publication Date
NL8700842A true NL8700842A (sh) 1988-11-01

Family

ID=19849836

Family Applications (1)

Application Number Title Priority Date Filing Date
NL8700842A NL8700842A (sh) 1987-04-10 1987-04-10

Country Status (8)

Country Link
EP (1) EP0289070A1 (sh)
JP (1) JPS63290848A (sh)
AU (1) AU611141B2 (sh)
DK (1) DK187288A (sh)
IL (1) IL85996A (sh)
NL (1) NL8700842A (sh)
NZ (1) NZ224170A (sh)
ZA (1) ZA882385B (sh)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2249548B (en) * 1988-06-03 1992-10-14 Wyeth John & Brother Ltd Aralkyl amine intermediates
GB8813185D0 (en) * 1988-06-03 1988-07-06 Wyeth John & Brother Ltd New method & amines used therein
HUT58270A (en) * 1989-06-02 1992-02-28 Wyeth John & Brother Ltd Process for producing amine derivatives and pharmaceutical compositions containing them
FR2681322B1 (fr) * 1991-09-12 1993-12-17 Laboratorios Dr Esteve Sa Derives d'aryl-heteroaryl-{n-[2-(3,4-dimethoxyphenyl)-ethyl]-n-methyl-3-aminopropoxy}-methane leur preparation et leur application en tant que medicaments .
GB9324244D0 (en) * 1993-11-25 1994-01-12 Merck Sharp & Dohme Therapeutic agents
IT1269826B (it) * 1994-05-24 1997-04-15 Paolo Minoia Uso di antagonisti degli oppiacei e di sali di calcio per la preparazione di medicamenti per il trattamento di forme patologiche endorfino-mediate
US20030170917A1 (en) * 2002-03-01 2003-09-11 Roche Diagnostics Corporation Compounds, antibodies, reagent kits, methods of producing antibodies, and methods of detecting analytes
US7101980B2 (en) 2002-03-01 2006-09-05 Roche Diagnostics Operations, Inc. Derivatives, conjugates, and antibodies for detecting ecstasy-class analytes
SI2368553T1 (sl) 2003-04-08 2015-05-29 Progenics Pharmaceuticals, Inc. Farmacevtske formulacije, vsebujoče metilnatrekson
US8524731B2 (en) 2005-03-07 2013-09-03 The University Of Chicago Use of opioid antagonists to attenuate endothelial cell proliferation and migration
US8518962B2 (en) 2005-03-07 2013-08-27 The University Of Chicago Use of opioid antagonists
ES2714198T3 (es) 2005-03-07 2019-05-27 Univ Chicago Uso de antagonistas opioideos para atenuar la proliferación y la migración de células endoteliales
US9662325B2 (en) 2005-03-07 2017-05-30 The University Of Chicago Use of opioid antagonists to attenuate endothelial cell proliferation and migration
AR057325A1 (es) 2005-05-25 2007-11-28 Progenics Pharm Inc Sintesis de (s)-n-metilnaltrexona, composiciones farmaceuticas y usos
AR057035A1 (es) 2005-05-25 2007-11-14 Progenics Pharm Inc SíNTESIS DE (R)-N-METILNALTREXONA, COMPOSICIONES FARMACÉUTICAS Y USOS
MX2009010550A (es) 2007-03-29 2009-12-14 Progenics Pharm Inc Formas de cristal de bromuro de (r)-n-metilnaltrexona y uso de las mismas.
PT2139890E (pt) 2007-03-29 2014-09-03 Wyeth Llc Antagonistas do receptor opióide periférico e respectivas utilizações
EP3064503A1 (en) 2007-03-29 2016-09-07 Progenics Pharmaceuticals, Inc. Peripheral opioid receptor antagonists and uses thereof
CA2713568C (en) 2008-02-06 2016-09-20 Progenics Pharmaceuticals, Inc. Preparation and use of (r),(r)-2,2'-bis-methylnaltrexone
WO2009117669A2 (en) 2008-03-21 2009-09-24 The University Of Chicago Treatment with opioid antagonists and mtor inhibitors
CA2676881C (en) 2008-09-30 2017-04-25 Wyeth Peripheral opioid receptor antagonists and uses thereof

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB586645A (en) * 1944-07-19 1947-03-26 Burroughs Wellcome Co Improvements relating to the synthesis of amino acid derivatives and salts thereof
GB587244A (en) * 1944-07-21 1947-04-18 Burroughs Wellcome Co Improvements relating to the synthesis of amino acid derivatives and salts thereof
DE1493602B2 (de) * 1965-04-13 1976-08-26 Deutsche Gold- Und Silber-Scheideanstalt Vormals Roessler, 6000 Frankfurt Verfahren zur herstellung von aminoketonen
DK129033B (da) * 1968-05-02 1974-08-12 Degussa Analogifremgangsmåde til fremstilling af propiophenonforbindelser eller deres optisk aktive isomere eller diastereomere eller salte eller kvaternære ammoniumforbindelser deraf.
NL178686C (nl) * 1974-04-08 1986-05-01 Duphar Int Res Werkwijze ter bereiding of vervaardiging van spasmolytisch werkzame preparaten en werkwijze ter bereiding van n-alkyl-n-gesubstitueerd alkylbeta-fenylethylaminen met spasmolytische werking.
NL7404732A (nl) * 1974-04-08 1975-10-10 Philips Nv Spasmolytice.
US4097500A (en) * 1977-07-25 1978-06-27 Morton-Norwich Products, Inc. N-Methyl-5-(4-nitrophenyl)-N-(a-methylphenethyl)furfurylamine hydrochloride
US4337207A (en) * 1980-09-04 1982-06-29 Regents Of The University Of California Biologically active catecholamine derivatives
NL8202810A (nl) * 1982-07-12 1984-02-01 Duphar Int Res Spasmolytisch werkzaam (+)-secoverine.
NL8300392A (nl) * 1983-02-03 1984-09-03 Duphar Int Res Nieuwe spasmolytisch werkzame propylcyclohexylketonderivaten.
EP0211254A3 (de) * 1985-07-31 1988-05-04 ASTA Pharma Aktiengesellschaft Neue cycloaliphatische Ketoamine
EG18188A (en) * 1986-05-01 1992-09-30 Pfizer Ltd Process for preparation anti-arhythmia agents

Also Published As

Publication number Publication date
DK187288D0 (da) 1988-04-06
IL85996A0 (en) 1988-09-30
ZA882385B (en) 1988-09-23
AU1434488A (en) 1988-10-13
NZ224170A (en) 1991-06-25
AU611141B2 (en) 1991-06-06
EP0289070A1 (en) 1988-11-02
IL85996A (en) 1991-12-12
DK187288A (da) 1988-10-11
JPS63290848A (ja) 1988-11-28

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Legal Events

Date Code Title Description
A1B A search report has been drawn up
AK Correction of former applications already laid open

Free format text: REFERENCES IN JOURNAL 21/88 ON PAGES 2441, 2445 AND 2451 SHOULD BE DELETED