GB2249548B - Aralkyl amine intermediates - Google Patents

Aralkyl amine intermediates

Info

Publication number
GB2249548B
GB2249548B GB9125683A GB9125683A GB2249548B GB 2249548 B GB2249548 B GB 2249548B GB 9125683 A GB9125683 A GB 9125683A GB 9125683 A GB9125683 A GB 9125683A GB 2249548 B GB2249548 B GB 2249548B
Authority
GB
United Kingdom
Prior art keywords
amine intermediates
aralkyl amine
aralkyl
intermediates
amine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
GB9125683A
Other versions
GB9125683D0 (en
GB2249548A (en
Inventor
Michael Christopher Wa Minchin
John Frederick White
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
John Wyeth and Brother Ltd
Original Assignee
John Wyeth and Brother Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB888813185A external-priority patent/GB8813185D0/en
Application filed by John Wyeth and Brother Ltd filed Critical John Wyeth and Brother Ltd
Priority to GB9125683A priority Critical patent/GB2249548B/en
Publication of GB9125683D0 publication Critical patent/GB9125683D0/en
Publication of GB2249548A publication Critical patent/GB2249548A/en
Application granted granted Critical
Publication of GB2249548B publication Critical patent/GB2249548B/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
    • C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C215/04—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated
    • C07C215/06—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic
    • C07C215/08—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic with only one hydroxy group and one amino group bound to the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/06—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
    • C07C229/10—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings
    • C07C229/14—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings to carbon atoms of carbon skeletons containing rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C237/06—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
    • C07C255/24—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the same saturated acyclic carbon skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
GB9125683A 1988-06-03 1991-12-02 Aralkyl amine intermediates Expired - Fee Related GB2249548B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB9125683A GB2249548B (en) 1988-06-03 1991-12-02 Aralkyl amine intermediates

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB888813185A GB8813185D0 (en) 1988-06-03 1988-06-03 New method & amines used therein
GB9125683A GB2249548B (en) 1988-06-03 1991-12-02 Aralkyl amine intermediates

Publications (3)

Publication Number Publication Date
GB9125683D0 GB9125683D0 (en) 1992-01-29
GB2249548A GB2249548A (en) 1992-05-13
GB2249548B true GB2249548B (en) 1992-10-14

Family

ID=26293969

Family Applications (1)

Application Number Title Priority Date Filing Date
GB9125683A Expired - Fee Related GB2249548B (en) 1988-06-03 1991-12-02 Aralkyl amine intermediates

Country Status (1)

Country Link
GB (1) GB2249548B (en)

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3712924A (en) * 1965-06-08 1973-01-23 Boehringer Sohn Ingelheim Halo-substituted 2-amino-benzylamineamides and salts thereof
GB1493416A (en) * 1974-04-08 1977-11-30 Philips Nv Spasmolytics
EP0099685A2 (en) * 1982-07-16 1984-02-01 The Upjohn Company (3-Pyridinyl)heteroalkanols and alkanoic acids and esters
EP0177078A1 (en) * 1984-09-12 1986-04-09 Duphar International Research B.V Spasmolytically active tertiary amine derivatives and method of preparing the same
EP0187122A2 (en) * 1985-01-03 1986-07-09 Ciba-Geigy Ag 1,3,4-Trisubstituted azacycloalkanes or azacycloalkenes
EP0289070A1 (en) * 1987-04-10 1988-11-02 Duphar International Research B.V Tertiary arylethyl amine derivatives having opiate-antagonistic activity

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3712924A (en) * 1965-06-08 1973-01-23 Boehringer Sohn Ingelheim Halo-substituted 2-amino-benzylamineamides and salts thereof
GB1493416A (en) * 1974-04-08 1977-11-30 Philips Nv Spasmolytics
EP0099685A2 (en) * 1982-07-16 1984-02-01 The Upjohn Company (3-Pyridinyl)heteroalkanols and alkanoic acids and esters
EP0177078A1 (en) * 1984-09-12 1986-04-09 Duphar International Research B.V Spasmolytically active tertiary amine derivatives and method of preparing the same
EP0187122A2 (en) * 1985-01-03 1986-07-09 Ciba-Geigy Ag 1,3,4-Trisubstituted azacycloalkanes or azacycloalkenes
EP0289070A1 (en) * 1987-04-10 1988-11-02 Duphar International Research B.V Tertiary arylethyl amine derivatives having opiate-antagonistic activity

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Bull. Soc. Chim. Belg. 86(1-2)35-8(1977) *

Also Published As

Publication number Publication date
GB9125683D0 (en) 1992-01-29
GB2249548A (en) 1992-05-13

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 20060602