DK187288A - Tertiaere arylethylaminderivater med opiatantagonistisk virkning - Google Patents

Tertiaere arylethylaminderivater med opiatantagonistisk virkning

Info

Publication number
DK187288A
DK187288A DK187288A DK187288A DK187288A DK 187288 A DK187288 A DK 187288A DK 187288 A DK187288 A DK 187288A DK 187288 A DK187288 A DK 187288A DK 187288 A DK187288 A DK 187288A
Authority
DK
Denmark
Prior art keywords
opiatantagonistic
tertiary
effect
arylethylamine
derivatives
Prior art date
Application number
DK187288A
Other languages
English (en)
Other versions
DK187288D0 (da
Inventor
Ineke Van Wijngaarden
Jacobus Antonius Jospeh Hartog
Martinus Theodorus Maria Tulp
Marinus Willem Lobbezoo
Original Assignee
Duphar Int Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Duphar Int Res filed Critical Duphar Int Res
Publication of DK187288D0 publication Critical patent/DK187288D0/da
Publication of DK187288A publication Critical patent/DK187288A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Addiction (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Pyrrole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Furan Compounds (AREA)
DK187288A 1987-04-10 1988-04-06 Tertiaere arylethylaminderivater med opiatantagonistisk virkning DK187288A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL8700842A NL8700842A (da) 1987-04-10 1987-04-10

Publications (2)

Publication Number Publication Date
DK187288D0 DK187288D0 (da) 1988-04-06
DK187288A true DK187288A (da) 1988-10-11

Family

ID=19849836

Family Applications (1)

Application Number Title Priority Date Filing Date
DK187288A DK187288A (da) 1987-04-10 1988-04-06 Tertiaere arylethylaminderivater med opiatantagonistisk virkning

Country Status (8)

Country Link
EP (1) EP0289070A1 (da)
JP (1) JPS63290848A (da)
AU (1) AU611141B2 (da)
DK (1) DK187288A (da)
IL (1) IL85996A (da)
NL (1) NL8700842A (da)
NZ (1) NZ224170A (da)
ZA (1) ZA882385B (da)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2249548B (en) * 1988-06-03 1992-10-14 Wyeth John & Brother Ltd Aralkyl amine intermediates
GB8813185D0 (en) * 1988-06-03 1988-07-06 Wyeth John & Brother Ltd New method & amines used therein
AU641394B2 (en) * 1989-06-02 1993-09-23 John Wyeth & Brother Limited Amines
FR2681322B1 (fr) * 1991-09-12 1993-12-17 Laboratorios Dr Esteve Sa Derives d'aryl-heteroaryl-{n-[2-(3,4-dimethoxyphenyl)-ethyl]-n-methyl-3-aminopropoxy}-methane leur preparation et leur application en tant que medicaments .
GB9324244D0 (en) * 1993-11-25 1994-01-12 Merck Sharp & Dohme Therapeutic agents
IT1269826B (it) * 1994-05-24 1997-04-15 Paolo Minoia Uso di antagonisti degli oppiacei e di sali di calcio per la preparazione di medicamenti per il trattamento di forme patologiche endorfino-mediate
US7101980B2 (en) 2002-03-01 2006-09-05 Roche Diagnostics Operations, Inc. Derivatives, conjugates, and antibodies for detecting ecstasy-class analytes
US20030170917A1 (en) * 2002-03-01 2003-09-11 Roche Diagnostics Corporation Compounds, antibodies, reagent kits, methods of producing antibodies, and methods of detecting analytes
DK2368553T3 (da) 2003-04-08 2015-02-09 Progenics Pharm Inc Lægemiddelsammensætning der omfatter methylnaltrexon
US9662325B2 (en) 2005-03-07 2017-05-30 The University Of Chicago Use of opioid antagonists to attenuate endothelial cell proliferation and migration
US8518962B2 (en) 2005-03-07 2013-08-27 The University Of Chicago Use of opioid antagonists
US8524731B2 (en) 2005-03-07 2013-09-03 The University Of Chicago Use of opioid antagonists to attenuate endothelial cell proliferation and migration
CN101171010B (zh) 2005-03-07 2014-09-17 芝加哥大学 阿片样物质拮抗剂用于减少内皮细胞增殖和迁移的用途
AR057325A1 (es) 2005-05-25 2007-11-28 Progenics Pharm Inc Sintesis de (s)-n-metilnaltrexona, composiciones farmaceuticas y usos
AR057035A1 (es) 2005-05-25 2007-11-14 Progenics Pharm Inc SíNTESIS DE (R)-N-METILNALTREXONA, COMPOSICIONES FARMACÉUTICAS Y USOS
PL2137191T3 (pl) 2007-03-29 2016-12-30 Antagoniści obwodowego receptora opioidowego i ich zastosowania
EP2134718A2 (en) 2007-03-29 2009-12-23 Progenics Pharmaceuticals, Inc. Crystal forms of (r)-n-methylnaltrexone bromide and uses thereof
PT2139890E (pt) 2007-03-29 2014-09-03 Wyeth Llc Antagonistas do receptor opióide periférico e respectivas utilizações
AU2008349873B2 (en) 2008-02-06 2014-02-13 Progenics Pharmaceuticals, Inc. Preparation and use of (R),(R)-2,2'-bis-methylnaltrexone
AU2009225434B2 (en) 2008-03-21 2014-05-22 The University Of Chicago Treatment with opioid antagonists and mTOR inhibitors
CA2676881C (en) 2008-09-30 2017-04-25 Wyeth Peripheral opioid receptor antagonists and uses thereof

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB586645A (en) * 1944-07-19 1947-03-26 Burroughs Wellcome Co Improvements relating to the synthesis of amino acid derivatives and salts thereof
GB587244A (en) * 1944-07-21 1947-04-18 Burroughs Wellcome Co Improvements relating to the synthesis of amino acid derivatives and salts thereof
DE1493602B2 (de) * 1965-04-13 1976-08-26 Deutsche Gold- Und Silber-Scheideanstalt Vormals Roessler, 6000 Frankfurt Verfahren zur herstellung von aminoketonen
SE365200B (da) * 1968-05-02 1974-03-18 Degussa
NL7404732A (nl) * 1974-04-08 1975-10-10 Philips Nv Spasmolytice.
NL178686C (nl) * 1974-04-08 1986-05-01 Duphar Int Res Werkwijze ter bereiding of vervaardiging van spasmolytisch werkzame preparaten en werkwijze ter bereiding van n-alkyl-n-gesubstitueerd alkylbeta-fenylethylaminen met spasmolytische werking.
US4097500A (en) * 1977-07-25 1978-06-27 Morton-Norwich Products, Inc. N-Methyl-5-(4-nitrophenyl)-N-(a-methylphenethyl)furfurylamine hydrochloride
US4337207A (en) * 1980-09-04 1982-06-29 Regents Of The University Of California Biologically active catecholamine derivatives
NL8202810A (nl) * 1982-07-12 1984-02-01 Duphar Int Res Spasmolytisch werkzaam (+)-secoverine.
NL8300392A (nl) * 1983-02-03 1984-09-03 Duphar Int Res Nieuwe spasmolytisch werkzame propylcyclohexylketonderivaten.
EP0211254A3 (de) * 1985-07-31 1988-05-04 ASTA Pharma Aktiengesellschaft Neue cycloaliphatische Ketoamine
EG18188A (en) * 1986-05-01 1992-09-30 Pfizer Ltd Process for preparation anti-arhythmia agents

Also Published As

Publication number Publication date
AU611141B2 (en) 1991-06-06
ZA882385B (en) 1988-09-23
NL8700842A (da) 1988-11-01
JPS63290848A (ja) 1988-11-28
IL85996A (en) 1991-12-12
DK187288D0 (da) 1988-04-06
NZ224170A (en) 1991-06-25
IL85996A0 (en) 1988-09-30
AU1434488A (en) 1988-10-13
EP0289070A1 (en) 1988-11-02

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment