DK651188A - Disulfidholdige pro-laegemidler med antitumorvirkning - Google Patents

Disulfidholdige pro-laegemidler med antitumorvirkning

Info

Publication number
DK651188A
DK651188A DK651188A DK651188A DK651188A DK 651188 A DK651188 A DK 651188A DK 651188 A DK651188 A DK 651188A DK 651188 A DK651188 A DK 651188A DK 651188 A DK651188 A DK 651188A
Authority
DK
Denmark
Prior art keywords
antitum
disulfid
medicines
effects
containing pro
Prior art date
Application number
DK651188A
Other languages
English (en)
Other versions
DK651188D0 (da
Inventor
Peter D Senter
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of DK651188D0 publication Critical patent/DK651188D0/da
Publication of DK651188A publication Critical patent/DK651188A/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Saccharide Compounds (AREA)
DK651188A 1987-11-23 1988-11-22 Disulfidholdige pro-laegemidler med antitumorvirkning DK651188A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US12431487A 1987-11-23 1987-11-23

Publications (2)

Publication Number Publication Date
DK651188D0 DK651188D0 (da) 1988-11-22
DK651188A true DK651188A (da) 1989-05-24

Family

ID=22414126

Family Applications (1)

Application Number Title Priority Date Filing Date
DK651188A DK651188A (da) 1987-11-23 1988-11-22 Disulfidholdige pro-laegemidler med antitumorvirkning

Country Status (11)

Country Link
EP (1) EP0317956A3 (da)
JP (1) JPH01165586A (da)
KR (1) KR910007977B1 (da)
AU (1) AU605648B2 (da)
DK (1) DK651188A (da)
FI (1) FI885360A (da)
IL (1) IL88427A0 (da)
NO (1) NO169959C (da)
NZ (1) NZ226956A (da)
PT (1) PT89063B (da)
ZA (1) ZA886812B (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69233669T2 (de) * 1991-10-23 2007-10-25 Cancer Research Technology Ltd. Bakterielle nitroreduktase zur reduzierung von cb 1954 und analogen davon in eine zytotoxische form
US6159706A (en) * 1997-12-23 2000-12-12 Newbiotics, Inc. Application of enzyme prodrugs as anti-infective agents
US7303760B2 (en) 1999-04-23 2007-12-04 Alza Corporation Method for treating multi-drug resistant tumors
US7238368B2 (en) 1999-04-23 2007-07-03 Alza Corporation Releasable linkage and compositions containing same
KR100669053B1 (ko) * 1999-04-23 2007-01-15 알자 코포레이션 리포좀에 사용하기 위한 절단가능 결합을 갖는 콘쥬게이트
TW200616604A (en) 2004-08-26 2006-06-01 Nicholas Piramal India Ltd Nitric oxide releasing prodrugs containing bio-cleavable linker
DE102005042044A1 (de) * 2005-09-02 2007-03-08 Behr Gmbh & Co. Kg Mechanisch gefügter Wärmetauscher

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2967337D1 (en) * 1978-06-16 1985-02-07 Kyowa Hakko Kogyo Kk Antithrombotic pharmaceutical preparation containing 2,2'-dithiobis benzamide derivatives and new 2,2'-dithiobis benzamide derivatives
DE116208T1 (de) * 1982-12-07 1985-02-28 Kyowa Hakko Kogyo Co., Ltd., Tokio/Tokyo Mitomycin-analoge.
US4803212A (en) * 1983-04-11 1989-02-07 Bristol-Myers Company Amino disulfides
PL138836B1 (en) * 1983-07-08 1986-11-29 Politechnika Gdanska Process for preparing novel n-substituted derivatives of anthracycline antibiotics
US4642352A (en) * 1983-12-23 1987-02-10 Bristol-Myers Company Acylamino mitosanes
JPS60255789A (ja) * 1984-06-01 1985-12-17 Kyowa Hakko Kogyo Co Ltd マイトマイシン誘導体，その製造法および抗腫瘍剤
AU581673B2 (en) * 1984-09-04 1989-03-02 Bristol-Myers Company Substituted 7-oxomitosanes
WO1986004898A1 (en) * 1985-02-22 1986-08-28 Kyowa Hakko Kogyo Co., Ltd. Disulfide compounds and antineoplastic agents
IL77334A (en) * 1985-12-16 1991-04-15 Univ Bar Ilan Synthesis of 9-epipodophyllotoxin glucoside derivatives and some novel intermediates therefor

Also Published As

Publication number Publication date
IL88427A0 (en) 1989-06-30
EP0317956A2 (en) 1989-05-31
AU2582688A (en) 1989-05-25
KR890007725A (ko) 1989-07-05
NO169959C (no) 1992-08-26
PT89063B (pt) 1993-03-31
FI885360A0 (fi) 1988-11-18
JPH01165586A (ja) 1989-06-29
EP0317956A3 (en) 1990-02-21
AU605648B2 (en) 1991-01-17
PT89063A (pt) 1988-12-01
NZ226956A (en) 1991-11-26
FI885360A (fi) 1989-05-24
NO169959B (no) 1992-05-18
DK651188D0 (da) 1988-11-22
NO885200D0 (no) 1988-11-22
KR910007977B1 (ko) 1991-10-05
ZA886812B (en) 1989-07-26
NO885200L (no) 1989-05-24

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment