IL88427A0 - Disulfide benzylcarbamate and-benzylcarbonate derivatives of anti-tumor drugs - Google Patents
Disulfide benzylcarbamate and-benzylcarbonate derivatives of anti-tumor drugsInfo
- Publication number
- IL88427A0 IL88427A0 IL88427A IL8842788A IL88427A0 IL 88427 A0 IL88427 A0 IL 88427A0 IL 88427 A IL88427 A IL 88427A IL 8842788 A IL8842788 A IL 8842788A IL 88427 A0 IL88427 A0 IL 88427A0
- Authority
- IL
- Israel
- Prior art keywords
- benzylcarbonate
- benzylcarbamate
- disulfide
- derivatives
- tumor drugs
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/14—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
- C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12431487A | 1987-11-23 | 1987-11-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL88427A0 true IL88427A0 (en) | 1989-06-30 |
Family
ID=22414126
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL88427A IL88427A0 (en) | 1987-11-23 | 1988-11-21 | Disulfide benzylcarbamate and-benzylcarbonate derivatives of anti-tumor drugs |
Country Status (11)
| Country | Link |
|---|---|
| EP (1) | EP0317956A3 (xx) |
| JP (1) | JPH01165586A (xx) |
| KR (1) | KR910007977B1 (xx) |
| AU (1) | AU605648B2 (xx) |
| DK (1) | DK651188A (xx) |
| FI (1) | FI885360A (xx) |
| IL (1) | IL88427A0 (xx) |
| NO (1) | NO169959C (xx) |
| NZ (1) | NZ226956A (xx) |
| PT (1) | PT89063B (xx) |
| ZA (1) | ZA886812B (xx) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0540263A1 (en) * | 1991-10-23 | 1993-05-05 | Cancer Research Campaign Technology Limited | Bacterial nitroreductase for the reduction of CB 1954 and analogues thereof to a cytotoxic form |
| US6159706A (en) * | 1997-12-23 | 2000-12-12 | Newbiotics, Inc. | Application of enzyme prodrugs as anti-infective agents |
| US7303760B2 (en) | 1999-04-23 | 2007-12-04 | Alza Corporation | Method for treating multi-drug resistant tumors |
| US7238368B2 (en) | 1999-04-23 | 2007-07-03 | Alza Corporation | Releasable linkage and compositions containing same |
| CA2369595C (en) * | 1999-04-23 | 2010-10-05 | Alza Corporation | Conjugate having a cleavable linkage for use in a liposome |
| TW200616604A (en) | 2004-08-26 | 2006-06-01 | Nicholas Piramal India Ltd | Nitric oxide releasing prodrugs containing bio-cleavable linker |
| DE102005042044A1 (de) * | 2005-09-02 | 2007-03-08 | Behr Gmbh & Co. Kg | Mechanisch gefügter Wärmetauscher |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0006227B1 (en) * | 1978-06-16 | 1984-12-27 | Kyowa Hakko Kogyo Co., Ltd | Antithrombotic pharmaceutical preparation containing 2,2'-dithiobis benzamide derivatives and new 2,2'-dithiobis benzamide derivatives |
| EP0116208B1 (en) * | 1982-12-07 | 1988-03-30 | Kyowa Hakko Kogyo Co., Ltd. | Mitomycin analogues |
| US4803212A (en) * | 1983-04-11 | 1989-02-07 | Bristol-Myers Company | Amino disulfides |
| PL138836B1 (en) * | 1983-07-08 | 1986-11-29 | Politechnika Gdanska | Process for preparing novel n-substituted derivatives of anthracycline antibiotics |
| US4642352A (en) * | 1983-12-23 | 1987-02-10 | Bristol-Myers Company | Acylamino mitosanes |
| JPS60255789A (ja) * | 1984-06-01 | 1985-12-17 | Kyowa Hakko Kogyo Co Ltd | マイトマイシン誘導体，その製造法および抗腫瘍剤 |
| AU581673B2 (en) * | 1984-09-04 | 1989-03-02 | Bristol-Myers Company | Substituted 7-oxomitosanes |
| WO1986004898A1 (en) * | 1985-02-22 | 1986-08-28 | Kyowa Hakko Kogyo Co., Ltd. | Disulfide compounds and antineoplastic agents |
| IL77334A (en) * | 1985-12-16 | 1991-04-15 | Univ Bar Ilan | Synthesis of 9-epipodophyllotoxin glucoside derivatives and some novel intermediates therefor |
-
1988
- 1988-09-13 ZA ZA886812A patent/ZA886812B/xx unknown
- 1988-11-14 NZ NZ226956A patent/NZ226956A/en unknown
- 1988-11-17 JP JP63289014A patent/JPH01165586A/ja active Pending
- 1988-11-18 FI FI885360A patent/FI885360A/fi not_active Application Discontinuation
- 1988-11-21 IL IL88427A patent/IL88427A0/xx unknown
- 1988-11-22 KR KR1019880015384A patent/KR910007977B1/ko not_active IP Right Cessation
- 1988-11-22 NO NO885200A patent/NO169959C/no unknown
- 1988-11-22 EP EP88119418A patent/EP0317956A3/en not_active Withdrawn
- 1988-11-22 DK DK651188A patent/DK651188A/da not_active Application Discontinuation
- 1988-11-23 AU AU25826/88A patent/AU605648B2/en not_active Ceased
- 1988-11-23 PT PT89063A patent/PT89063B/pt not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| NO885200D0 (no) | 1988-11-22 |
| JPH01165586A (ja) | 1989-06-29 |
| KR910007977B1 (ko) | 1991-10-05 |
| FI885360A0 (fi) | 1988-11-18 |
| NZ226956A (en) | 1991-11-26 |
| KR890007725A (ko) | 1989-07-05 |
| EP0317956A2 (en) | 1989-05-31 |
| FI885360A (fi) | 1989-05-24 |
| NO169959C (no) | 1992-08-26 |
| DK651188D0 (da) | 1988-11-22 |
| DK651188A (da) | 1989-05-24 |
| PT89063B (pt) | 1993-03-31 |
| AU2582688A (en) | 1989-05-25 |
| EP0317956A3 (en) | 1990-02-21 |
| NO169959B (no) | 1992-05-18 |
| NO885200L (no) | 1989-05-24 |
| AU605648B2 (en) | 1991-01-17 |
| ZA886812B (en) | 1989-07-26 |
| PT89063A (pt) | 1988-12-01 |
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