NL8201987A - Werkwijze voor het bepalen van de activiteit van plasminogeenactivator van het weefseltype, alsmede voor gebruik bij deze werkwijze geschikte combinatie van het "kit"-type. - Google Patents

Werkwijze voor het bepalen van de activiteit van plasminogeenactivator van het weefseltype, alsmede voor gebruik bij deze werkwijze geschikte combinatie van het "kit"-type. Download PDF

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Publication number
NL8201987A
NL8201987A NL8201987A NL8201987A NL8201987A NL 8201987 A NL8201987 A NL 8201987A NL 8201987 A NL8201987 A NL 8201987A NL 8201987 A NL8201987 A NL 8201987A NL 8201987 A NL8201987 A NL 8201987A
Authority
NL
Netherlands
Prior art keywords
fibrinogen
plasminogen
fibrin
fragments
combination according
Prior art date
Application number
NL8201987A
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English (en)
Dutch (nl)
Original Assignee
Tno
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tno filed Critical Tno
Priority to NL8201987A priority Critical patent/NL8201987A/nl
Priority to US06/492,494 priority patent/US4563420A/en
Priority to EP83200670A priority patent/EP0094720B1/de
Priority to AT83200670T priority patent/ATE22928T1/de
Priority to DE8383200670T priority patent/DE3366963D1/de
Priority to JP58083972A priority patent/JPS58209999A/ja
Publication of NL8201987A publication Critical patent/NL8201987A/nl

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/56—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2337/00—N-linked chromogens for determinations of peptidases and proteinases
    • C12Q2337/10—Anilides
    • C12Q2337/12—Para-Nitroanilides p-NA
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/745—Assays involving non-enzymic blood coagulation factors
    • G01N2333/75—Fibrin; Fibrinogen
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/968—Plasmin, i.e. fibrinolysin
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/972—Plasminogen activators
    • G01N2333/9726—Tissue plasminogen activator

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Neurosurgery (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
NL8201987A 1982-05-13 1982-05-13 Werkwijze voor het bepalen van de activiteit van plasminogeenactivator van het weefseltype, alsmede voor gebruik bij deze werkwijze geschikte combinatie van het "kit"-type. NL8201987A (nl)

Priority Applications (6)

Application Number Priority Date Filing Date Title
NL8201987A NL8201987A (nl) 1982-05-13 1982-05-13 Werkwijze voor het bepalen van de activiteit van plasminogeenactivator van het weefseltype, alsmede voor gebruik bij deze werkwijze geschikte combinatie van het "kit"-type.
US06/492,494 US4563420A (en) 1982-05-13 1983-05-06 Process for assaying the activity of tissue plasminogen activator, and kit suitable for use in said process
EP83200670A EP0094720B1 (de) 1982-05-13 1983-05-09 Verfahren zur Bestimmung der Wirksamkeit von Plasminogen-Aktivator des Gewebes und zur Verwendung in diesem Verfahren geeigneter Reagenzsatz
AT83200670T ATE22928T1 (de) 1982-05-13 1983-05-09 Verfahren zur bestimmung der wirksamkeit von plasminogen-aktivator des gewebes und zur verwendung in diesem verfahren geeigneter reagenzsatz.
DE8383200670T DE3366963D1 (en) 1982-05-13 1983-05-09 Process for assaying the activity of tissue plasminogen activator, and kit suitable for use in said process
JP58083972A JPS58209999A (ja) 1982-05-13 1983-05-13 組織プラスミノゲンアクチベ−タ−の活性を検定する方法及びその方法に使用するキツト

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NL8201987 1982-05-13
NL8201987A NL8201987A (nl) 1982-05-13 1982-05-13 Werkwijze voor het bepalen van de activiteit van plasminogeenactivator van het weefseltype, alsmede voor gebruik bij deze werkwijze geschikte combinatie van het "kit"-type.

Publications (1)

Publication Number Publication Date
NL8201987A true NL8201987A (nl) 1983-12-01

Family

ID=19839733

Family Applications (1)

Application Number Title Priority Date Filing Date
NL8201987A NL8201987A (nl) 1982-05-13 1982-05-13 Werkwijze voor het bepalen van de activiteit van plasminogeenactivator van het weefseltype, alsmede voor gebruik bij deze werkwijze geschikte combinatie van het "kit"-type.

Country Status (6)

Country Link
US (1) US4563420A (de)
EP (1) EP0094720B1 (de)
JP (1) JPS58209999A (de)
AT (1) ATE22928T1 (de)
DE (1) DE3366963D1 (de)
NL (1) NL8201987A (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1254119A (en) * 1984-07-20 1989-05-16 Lloyd A. Schick Single step protease inhibitor assay
DE3430906A1 (de) * 1984-08-22 1986-02-27 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren zur bestimmung von fibrinmonomer in plasma
US4753879A (en) * 1984-08-27 1988-06-28 Biogen N.V. Modified tissue plasminogen activators
DE3512909A1 (de) * 1985-04-11 1986-10-23 Behringwerke Ag, 3550 Marburg Verfahren zur bestimmung von plasminogenaktivatoren (pa)
US5096811A (en) * 1986-03-12 1992-03-17 Genentech, Inc. Novel assay system for measuring human plasminogen actuator activity
AT388618B (de) * 1987-05-05 1989-08-10 Binder Bernd Dr Verfahren zur quantitativen bestimmung von funktion und antigener konzentration einer in einer biologischen fluessigkeit enthaltenen substanz
SE8702556D0 (sv) * 1987-06-18 1987-06-18 Kabivitrum Ab Bestemning av vid proteolys aktiva komponenter
US5312745A (en) * 1987-06-18 1994-05-17 Chromogenix Ab Determination of components active in proteolysis
JP2520424B2 (ja) * 1987-07-03 1996-07-31 帝人株式会社 血液線溶活性の測定方法
ATE185376T1 (de) * 1987-07-06 1999-10-15 Biopool Int Inc Verfahren zur messung von gewebeplasminogenaktivator, antithrombin-iii und lösliches fibrin
EP0576039A3 (en) * 1987-07-06 1994-06-08 Biopool Int Inc Method of determining tissue plasminogen activator activity in biological fluids
US5114845A (en) * 1987-07-06 1992-05-19 Biopool International, Inc. Assays for plasminogen activator inhibitor and soluble fibrin
US5206140A (en) * 1988-06-24 1993-04-27 Research Corporation Technologies, Inc. Assay for soluble crosslinked fibrin polymers
NL8802710A (nl) * 1988-11-04 1990-06-01 Tno Werkwijze voor het bepalen van een enzym en daarvoor geschikte kit en stof.
DE3843422A1 (de) * 1988-12-23 1990-06-28 Behringwerke Ag Verfahren zur bestimmung der plasminogenaktivator-aktivitaet in alpha-2-antiplasmin-haltigen proben
FI91777C (fi) * 1990-04-02 1994-08-10 Elomit Oy Menetelmä plasmiiniaktiivisuuden määrittämiseksi
JPH04233458A (ja) * 1990-08-23 1992-08-21 New York Blood Center Inc 可溶性フィブリン様モノマーを使ったアッセイ
WO2000065349A2 (en) * 1999-04-28 2000-11-02 Cardiogenics Inc. Method for determining plasminogen activator inhibitor
AU2006281969B2 (en) * 2005-08-12 2011-10-06 Biopower Systems Pty. Ltd. A mooring

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2431342C3 (de) * 1973-07-27 1978-10-26 Behringwerke Ag, 3550 Marburg Verfahren zur Messung des Plasminogengehaltes durch Bestimmung der Bildung von Fibrin in einer Probe
SE407571B (sv) * 1975-07-11 1979-04-02 Kabi Ab Nya kromogena enzymsubstrat for serinproteaser
CH634662A5 (de) * 1976-05-28 1983-02-15 Pentapharm Ag Verwendung von tripeptidderivaten zur quantitativen bestimmung von plasminogen-aktivatoren.

Also Published As

Publication number Publication date
ATE22928T1 (de) 1986-11-15
JPS58209999A (ja) 1983-12-07
US4563420A (en) 1986-01-07
EP0094720A1 (de) 1983-11-23
DE3366963D1 (en) 1986-11-20
JPH0417640B2 (de) 1992-03-26
EP0094720B1 (de) 1986-10-15

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A1B A search report has been drawn up
A85 Still pending on 85-01-01
BV The patent application has lapsed