NL7907483A - Therapeutisch preparaat voor de behandeling van infecties en ziekten van fokdieren. - Google Patents
Therapeutisch preparaat voor de behandeling van infecties en ziekten van fokdieren. Download PDFInfo
- Publication number
- NL7907483A NL7907483A NL7907483A NL7907483A NL7907483A NL 7907483 A NL7907483 A NL 7907483A NL 7907483 A NL7907483 A NL 7907483A NL 7907483 A NL7907483 A NL 7907483A NL 7907483 A NL7907483 A NL 7907483A
- Authority
- NL
- Netherlands
- Prior art keywords
- days
- affected
- treatment
- drinking water
- feed
- Prior art date
Links
- 238000011282 treatment Methods 0.000 title claims description 48
- 238000002360 preparation method Methods 0.000 title claims description 32
- 230000001225 therapeutic effect Effects 0.000 title claims description 21
- 241001465754 Metazoa Species 0.000 title description 19
- 208000015181 infectious disease Diseases 0.000 title description 18
- 201000010099 disease Diseases 0.000 title description 5
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title description 5
- 239000003651 drinking water Substances 0.000 claims description 45
- 235000020188 drinking water Nutrition 0.000 claims description 45
- 208000003495 Coccidiosis Diseases 0.000 claims description 29
- 206010023076 Isosporiasis Diseases 0.000 claims description 29
- 241000283973 Oryctolagus cuniculus Species 0.000 claims description 25
- 241000286209 Phasianidae Species 0.000 claims description 23
- QKLPUVXBJHRFQZ-UHFFFAOYSA-N 4-amino-n-(6-chloropyrazin-2-yl)benzenesulfonamide Chemical compound C1=CC(N)=CC=C1S(=O)(=O)NC1=CN=CC(Cl)=N1 QKLPUVXBJHRFQZ-UHFFFAOYSA-N 0.000 claims description 20
- IEDVJHCEMCRBQM-UHFFFAOYSA-N trimethoprim Chemical compound COC1=C(OC)C(OC)=CC(CC=2C(=NC(N)=NC=2)N)=C1 IEDVJHCEMCRBQM-UHFFFAOYSA-N 0.000 claims description 13
- 229960001082 trimethoprim Drugs 0.000 claims description 13
- 244000309466 calf Species 0.000 claims description 11
- 244000144977 poultry Species 0.000 claims description 11
- 239000013543 active substance Substances 0.000 claims description 10
- 241000282887 Suidae Species 0.000 claims description 9
- 208000035143 Bacterial infection Diseases 0.000 claims description 5
- 208000022362 bacterial infectious disease Diseases 0.000 claims description 5
- -1 methyl Chemical group 0.000 claims description 2
- 235000013384 milk substitute Nutrition 0.000 claims description 2
- 235000021056 liquid food Nutrition 0.000 claims 1
- 230000037396 body weight Effects 0.000 description 17
- 238000009395 breeding Methods 0.000 description 17
- 230000001488 breeding effect Effects 0.000 description 17
- 150000003456 sulfonamides Chemical class 0.000 description 13
- 229940124530 sulfonamide Drugs 0.000 description 12
- 241000287828 Gallus gallus Species 0.000 description 11
- 239000000203 mixture Substances 0.000 description 10
- 230000000241 respiratory effect Effects 0.000 description 10
- 230000000844 anti-bacterial effect Effects 0.000 description 9
- 235000013594 poultry meat Nutrition 0.000 description 9
- 238000003307 slaughter Methods 0.000 description 9
- 235000013372 meat Nutrition 0.000 description 8
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 description 7
- 239000003242 anti bacterial agent Substances 0.000 description 7
- 239000008101 lactose Substances 0.000 description 7
- 206010008631 Cholera Diseases 0.000 description 6
- 230000000694 effects Effects 0.000 description 6
- 239000004098 Tetracycline Substances 0.000 description 5
- 229940088710 antibiotic agent Drugs 0.000 description 5
- 150000001875 compounds Chemical class 0.000 description 5
- 230000002458 infectious effect Effects 0.000 description 5
- 230000000968 intestinal effect Effects 0.000 description 5
- 206010039083 rhinitis Diseases 0.000 description 5
- 239000000126 substance Substances 0.000 description 5
- 235000019364 tetracycline Nutrition 0.000 description 5
- 150000003522 tetracyclines Chemical class 0.000 description 5
- 229940040944 tetracyclines Drugs 0.000 description 5
- 241000271566 Aves Species 0.000 description 4
- 241000894006 Bacteria Species 0.000 description 4
- 241000224483 Coccidia Species 0.000 description 4
- 206010036030 Polyarthritis Diseases 0.000 description 4
- 206010003246 arthritis Diseases 0.000 description 4
- 230000015572 biosynthetic process Effects 0.000 description 4
- OVBPIULPVIDEAO-LBPRGKRZSA-N folic acid Chemical compound C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)N[C@@H](CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-LBPRGKRZSA-N 0.000 description 4
- 235000013305 food Nutrition 0.000 description 4
- 208000030428 polyarticular arthritis Diseases 0.000 description 4
- ZZORFUFYDOWNEF-UHFFFAOYSA-N sulfadimethoxine Chemical compound COC1=NC(OC)=CC(NS(=O)(=O)C=2C=CC(N)=CC=2)=N1 ZZORFUFYDOWNEF-UHFFFAOYSA-N 0.000 description 4
- 229960000973 sulfadimethoxine Drugs 0.000 description 4
- ACTOXUHEUCPTEW-BWHGAVFKSA-N 2-[(4r,5s,6s,7r,9r,10r,11e,13e,16r)-6-[(2s,3r,4r,5s,6r)-5-[(2s,4r,5s,6s)-4,5-dihydroxy-4,6-dimethyloxan-2-yl]oxy-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-10-[(2s,5s,6r)-5-(dimethylamino)-6-methyloxan-2-yl]oxy-4-hydroxy-5-methoxy-9,16-dimethyl-2-o Chemical compound O([C@H]1/C=C/C=C/C[C@@H](C)OC(=O)C[C@@H](O)[C@@H]([C@H]([C@@H](CC=O)C[C@H]1C)O[C@H]1[C@@H]([C@H]([C@H](O[C@@H]2O[C@@H](C)[C@H](O)[C@](C)(O)C2)[C@@H](C)O1)N(C)C)O)OC)[C@@H]1CC[C@H](N(C)C)[C@@H](C)O1 ACTOXUHEUCPTEW-BWHGAVFKSA-N 0.000 description 3
- 241000321096 Adenoides Species 0.000 description 3
- 208000014085 Chronic respiratory disease Diseases 0.000 description 3
- 241000223931 Eimeria acervulina Species 0.000 description 3
- 241000223932 Eimeria tenella Species 0.000 description 3
- 241000186810 Erysipelothrix rhusiopathiae Species 0.000 description 3
- OVBPIULPVIDEAO-UHFFFAOYSA-N N-Pteroyl-L-glutaminsaeure Natural products C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)NC(CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-UHFFFAOYSA-N 0.000 description 3
- 206010035664 Pneumonia Diseases 0.000 description 3
- 206010039438 Salmonella Infections Diseases 0.000 description 3
- 239000004187 Spiramycin Substances 0.000 description 3
- 210000002534 adenoid Anatomy 0.000 description 3
- LDBTVAXGKYIFHO-UHFFFAOYSA-N diaveridine Chemical compound C1=C(OC)C(OC)=CC=C1CC1=CN=C(N)N=C1N LDBTVAXGKYIFHO-UHFFFAOYSA-N 0.000 description 3
- 229950000246 diaveridine Drugs 0.000 description 3
- 229940079593 drug Drugs 0.000 description 3
- 239000003814 drug Substances 0.000 description 3
- 238000002474 experimental method Methods 0.000 description 3
- 229960000304 folic acid Drugs 0.000 description 3
- 235000019152 folic acid Nutrition 0.000 description 3
- 239000011724 folic acid Substances 0.000 description 3
- 230000005764 inhibitory process Effects 0.000 description 3
- 206010039447 salmonellosis Diseases 0.000 description 3
- 235000019372 spiramycin Nutrition 0.000 description 3
- 229960001294 spiramycin Drugs 0.000 description 3
- 229930191512 spiramycin Natural products 0.000 description 3
- XOXHILFPRYWFOD-UHFFFAOYSA-N sulfachloropyridazine Chemical compound C1=CC(N)=CC=C1S(=O)(=O)NC1=CC=C(Cl)N=N1 XOXHILFPRYWFOD-UHFFFAOYSA-N 0.000 description 3
- 229950008831 sulfachlorpyridazine Drugs 0.000 description 3
- 229960002135 sulfadimidine Drugs 0.000 description 3
- ASWVTGNCAZCNNR-UHFFFAOYSA-N sulfamethazine Chemical compound CC1=CC(C)=NC(NS(=O)(=O)C=2C=CC(N)=CC=2)=N1 ASWVTGNCAZCNNR-UHFFFAOYSA-N 0.000 description 3
- 238000002560 therapeutic procedure Methods 0.000 description 3
- YVQVOQKFMFRVGR-VGOFMYFVSA-N 5-(morpholin-4-ylmethyl)-3-[(e)-(5-nitrofuran-2-yl)methylideneamino]-1,3-oxazolidin-2-one Chemical compound O1C([N+](=O)[O-])=CC=C1\C=N\N1C(=O)OC(CN2CCOCC2)C1 YVQVOQKFMFRVGR-VGOFMYFVSA-N 0.000 description 2
- FEWJPZIEWOKRBE-JCYAYHJZSA-N Dextrotartaric acid Chemical compound OC(=O)[C@H](O)[C@@H](O)C(O)=O FEWJPZIEWOKRBE-JCYAYHJZSA-N 0.000 description 2
- 241000223924 Eimeria Species 0.000 description 2
- 241001452550 Eimeria meleagridis Species 0.000 description 2
- 241001278028 Eimeria meleagrimitis Species 0.000 description 2
- 241000499563 Eimeria necatrix Species 0.000 description 2
- 206010034107 Pasteurella infections Diseases 0.000 description 2
- 230000001580 bacterial effect Effects 0.000 description 2
- 230000003115 biocidal effect Effects 0.000 description 2
- 239000003795 chemical substances by application Substances 0.000 description 2
- 235000013330 chicken meat Nutrition 0.000 description 2
- 235000005911 diet Nutrition 0.000 description 2
- 230000037213 diet Effects 0.000 description 2
- 235000013601 eggs Nutrition 0.000 description 2
- 229950000337 furaltadone Drugs 0.000 description 2
- 229960001625 furazolidone Drugs 0.000 description 2
- PLHJDBGFXBMTGZ-WEVVVXLNSA-N furazolidone Chemical compound O1C([N+](=O)[O-])=CC=C1\C=N\N1C(=O)OCC1 PLHJDBGFXBMTGZ-WEVVVXLNSA-N 0.000 description 2
- 230000002496 gastric effect Effects 0.000 description 2
- 210000004072 lung Anatomy 0.000 description 2
- 230000004060 metabolic process Effects 0.000 description 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 2
- 201000005115 pasteurellosis Diseases 0.000 description 2
- 229960000268 spectinomycin Drugs 0.000 description 2
- UNFWWIHTNXNPBV-WXKVUWSESA-N spectinomycin Chemical compound O([C@@H]1[C@@H](NC)[C@@H](O)[C@H]([C@@H]([C@H]1O1)O)NC)[C@]2(O)[C@H]1O[C@H](C)CC2=O UNFWWIHTNXNPBV-WXKVUWSESA-N 0.000 description 2
- 208000024891 symptom Diseases 0.000 description 2
- 208000011580 syndromic disease Diseases 0.000 description 2
- 229940095064 tartrate Drugs 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 125000005809 3,4,5-trimethoxyphenyl group Chemical group [H]C1=C(OC([H])([H])[H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1* 0.000 description 1
- OLGCJTRSPFQVOV-UHFFFAOYSA-N 4-amino-n-(5,6-dimethoxypyrimidin-4-yl)benzenesulfonamide;5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-diamine Chemical compound COC1=C(OC)C(OC)=CC(CC=2C(=NC(N)=NC=2)N)=C1.COC1=NC=NC(NS(=O)(=O)C=2C=CC(N)=CC=2)=C1OC OLGCJTRSPFQVOV-UHFFFAOYSA-N 0.000 description 1
- WZRJTRPJURQBRM-UHFFFAOYSA-N 4-amino-n-(5-methyl-1,2-oxazol-3-yl)benzenesulfonamide;5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-diamine Chemical compound O1C(C)=CC(NS(=O)(=O)C=2C=CC(N)=CC=2)=N1.COC1=C(OC)C(OC)=CC(CC=2C(=NC(N)=NC=2)N)=C1 WZRJTRPJURQBRM-UHFFFAOYSA-N 0.000 description 1
- MSTNYGQPCMXVAQ-KIYNQFGBSA-N 5,6,7,8-tetrahydrofolic acid Chemical compound N1C=2C(=O)NC(N)=NC=2NCC1CNC1=CC=C(C(=O)N[C@@H](CCC(O)=O)C(O)=O)C=C1 MSTNYGQPCMXVAQ-KIYNQFGBSA-N 0.000 description 1
- 244000291564 Allium cepa Species 0.000 description 1
- 235000002732 Allium cepa var. cepa Nutrition 0.000 description 1
- 201000004813 Bronchopneumonia Diseases 0.000 description 1
- 239000004099 Chlortetracycline Substances 0.000 description 1
- 241001465977 Coccoidea Species 0.000 description 1
- 241000289819 Eimeria adenoeides Species 0.000 description 1
- 102100032950 GPI mannosyltransferase 1 Human genes 0.000 description 1
- 101710100495 GPI mannosyltransferase 1 Proteins 0.000 description 1
- 241000102293 Leucocytozoon sp. Species 0.000 description 1
- 102000004316 Oxidoreductases Human genes 0.000 description 1
- 108090000854 Oxidoreductases Proteins 0.000 description 1
- 102100036162 Phosphatidylinositol N-acetylglucosaminyltransferase subunit H Human genes 0.000 description 1
- 101710109736 Phosphatidylinositol N-acetylglucosaminyltransferase subunit H Proteins 0.000 description 1
- 102100035188 Phosphatidylinositol N-acetylglucosaminyltransferase subunit P Human genes 0.000 description 1
- 101710109728 Phosphatidylinositol N-acetylglucosaminyltransferase subunit P Proteins 0.000 description 1
- 206010037660 Pyrexia Diseases 0.000 description 1
- 241000209140 Triticum Species 0.000 description 1
- 235000021307 Triticum Nutrition 0.000 description 1
- LCTXBFGHZLGBNU-UHFFFAOYSA-M amprolium Chemical compound [Cl-].NC1=NC(CCC)=NC=C1C[N+]1=CC=CC=C1C LCTXBFGHZLGBNU-UHFFFAOYSA-M 0.000 description 1
- 229960003683 amprolium Drugs 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- 230000003385 bacteriostatic effect Effects 0.000 description 1
- 229940098166 bactrim Drugs 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- CYDMQBQPVICBEU-UHFFFAOYSA-N chlorotetracycline Natural products C1=CC(Cl)=C2C(O)(C)C3CC4C(N(C)C)C(O)=C(C(N)=O)C(=O)C4(O)C(O)=C3C(=O)C2=C1O CYDMQBQPVICBEU-UHFFFAOYSA-N 0.000 description 1
- 229960004475 chlortetracycline Drugs 0.000 description 1
- CYDMQBQPVICBEU-XRNKAMNCSA-N chlortetracycline Chemical compound C1=CC(Cl)=C2[C@](O)(C)[C@H]3C[C@H]4[C@H](N(C)C)C(O)=C(C(N)=O)C(=O)[C@@]4(O)C(O)=C3C(=O)C2=C1O CYDMQBQPVICBEU-XRNKAMNCSA-N 0.000 description 1
- 235000019365 chlortetracycline Nutrition 0.000 description 1
- 230000001684 chronic effect Effects 0.000 description 1
- 238000012790 confirmation Methods 0.000 description 1
- OZRNSSUDZOLUSN-LBPRGKRZSA-N dihydrofolic acid Chemical compound N=1C=2C(=O)NC(N)=NC=2NCC=1CNC1=CC=C(C(=O)N[C@@H](CCC(O)=O)C(O)=O)C=C1 OZRNSSUDZOLUSN-LBPRGKRZSA-N 0.000 description 1
- 230000002045 lasting effect Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 210000003205 muscle Anatomy 0.000 description 1
- XCTDPFHKIGVRLA-UHFFFAOYSA-N n-[4-(1,3-thiazol-2-ylsulfamoyl)phenyl]formamide Chemical compound C1=CC(NC=O)=CC=C1S(=O)(=O)NC1=NC=CS1 XCTDPFHKIGVRLA-UHFFFAOYSA-N 0.000 description 1
- 239000002547 new drug Substances 0.000 description 1
- 208000001297 phlebitis Diseases 0.000 description 1
- 230000008092 positive effect Effects 0.000 description 1
- 150000003212 purines Chemical class 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 208000023504 respiratory system disease Diseases 0.000 description 1
- 241000894007 species Species 0.000 description 1
- JLKIGFTWXXRPMT-UHFFFAOYSA-N sulphamethoxazole Chemical compound O1C(C)=CC(NS(=O)(=O)C=2C=CC(N)=CC=2)=N1 JLKIGFTWXXRPMT-UHFFFAOYSA-N 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 230000002195 synergetic effect Effects 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
- A61K31/635—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/116—Heterocyclic compounds
- A23K20/137—Heterocyclic compounds containing two hetero atoms, of which at least one is nitrogen
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/30—Feeding-stuffs specially adapted for particular animals for swines
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Polymers & Plastics (AREA)
- Health & Medical Sciences (AREA)
- Animal Husbandry (AREA)
- Food Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Epidemiology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Birds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Fodder In General (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT2854978 | 1978-10-09 | ||
| IT28549/78A IT1099795B (it) | 1978-10-09 | 1978-10-09 | Composizione terapeutica per il trattamento di infezioni e malattie di animali da allevamento |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NL7907483A true NL7907483A (nl) | 1980-04-11 |
Family
ID=11223772
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NL7907483A NL7907483A (nl) | 1978-10-09 | 1979-10-09 | Therapeutisch preparaat voor de behandeling van infecties en ziekten van fokdieren. |
Country Status (7)
| Country | Link |
|---|---|
| AU (1) | AU5161579A (it) |
| DE (1) | DE2940934A1 (it) |
| FR (1) | FR2438480A1 (it) |
| GB (1) | GB2033224A (it) |
| GR (1) | GR73098B (it) |
| IT (1) | IT1099795B (it) |
| NL (1) | NL7907483A (it) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5132288A (en) * | 1989-07-31 | 1992-07-21 | Michael Foods, Inc. | Method for controlling Salmonella enteritidis in poultry |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2963584D1 (en) * | 1978-08-01 | 1982-10-21 | Ciba Geigy Ag | Stable, liquid pharmaceutical formulation, its preparation and use |
-
1978
- 1978-10-09 IT IT28549/78A patent/IT1099795B/it active
-
1979
- 1979-10-08 GB GB7934883A patent/GB2033224A/en not_active Withdrawn
- 1979-10-08 FR FR7924965A patent/FR2438480A1/fr active Pending
- 1979-10-08 GR GR60210A patent/GR73098B/el unknown
- 1979-10-09 NL NL7907483A patent/NL7907483A/nl not_active Application Discontinuation
- 1979-10-09 AU AU51615/79A patent/AU5161579A/en not_active Abandoned
- 1979-10-09 DE DE19792940934 patent/DE2940934A1/de not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| DE2940934A1 (de) | 1980-04-24 |
| FR2438480A1 (fr) | 1980-05-09 |
| GR73098B (it) | 1984-02-01 |
| GB2033224A (en) | 1980-05-21 |
| IT7828549A0 (it) | 1978-10-09 |
| AU5161579A (en) | 1981-04-16 |
| IT1099795B (it) | 1985-09-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| BV | The patent application has lapsed |