NL7608962A - Werkwijze voor de bereiding van nieuwe n-((1-piperidinyl)alkyl)arylcarbonamidederivaten. - Google Patents

Werkwijze voor de bereiding van nieuwe n-((1-piperidinyl)alkyl)arylcarbonamidederivaten.

Info

Publication number
NL7608962A
NL7608962A NL7608962A NL7608962A NL7608962A NL 7608962 A NL7608962 A NL 7608962A NL 7608962 A NL7608962 A NL 7608962A NL 7608962 A NL7608962 A NL 7608962A NL 7608962 A NL7608962 A NL 7608962A
Authority
NL
Netherlands
Prior art keywords
arylcarbonamide
piperidinyl
derivatives
alkyl
preparation
Prior art date
Application number
NL7608962A
Other languages
English (en)
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/604,159 external-priority patent/US3997566A/en
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of NL7608962A publication Critical patent/NL7608962A/nl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J37/00—Processes, in general, for preparing catalysts; Processes, in general, for activation of catalysts
    • B01J37/20—Sulfiding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0016—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing only hydroxy, etherified or esterified hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/377—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by splitting-off hydrogen or functional groups; by hydrogenolysis of functional groups
    • C07C51/38—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by splitting-off hydrogen or functional groups; by hydrogenolysis of functional groups by decarboxylation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D203/00—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D203/04—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D203/06—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D203/16—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with acylated ring nitrogen atoms
    • C07D203/18—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with acylated ring nitrogen atoms by carboxylic acids, or by sulfur or nitrogen analogues thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/44—Oxygen atoms attached in position 4
    • C07D211/52—Oxygen atoms attached in position 4 having an aryl radical as the second substituent in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56—Nitrogen atoms
    • C07D211/58—Nitrogen atoms attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/04—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10—Oxygen atoms
    • C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
    • C07D319/06—1,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
    • C—CHEMISTRY; METALLURGY
    • C10—PETROLEUM, GAS OR COKE INDUSTRIES; TECHNICAL GASES CONTAINING CARBON MONOXIDE; FUELS; LUBRICANTS; PEAT
    • C10G—CRACKING HYDROCARBON OILS; PRODUCTION OF LIQUID HYDROCARBON MIXTURES, e.g. BY DESTRUCTIVE HYDROGENATION, OLIGOMERISATION, POLYMERISATION; RECOVERY OF HYDROCARBON OILS FROM OIL-SHALE, OIL-SAND, OR GASES; REFINING MIXTURES MAINLY CONSISTING OF HYDROCARBONS; REFORMING OF NAPHTHA; MINERAL WAXES
    • C10G35/00—Reforming naphtha
    • C10G35/22—Starting-up reforming operations

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • General Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Materials Engineering (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Production Of Liquid Hydrocarbon Mixture For Refining Petroleum (AREA)
  • Catalysts (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
NL7608962A 1975-08-13 1976-08-12 Werkwijze voor de bereiding van nieuwe n-((1-piperidinyl)alkyl)arylcarbonamidederivaten. NL7608962A (nl)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US60415875A 1975-08-13 1975-08-13
US60428275A 1975-08-13 1975-08-13
US05/604,159 US3997566A (en) 1975-02-24 1975-08-13 Tricyclic prostaglandin
US05/621,047 US4048058A (en) 1975-08-13 1975-10-09 Methods to be used in reforming processes employing multi-metallic catalysts
US67787476A 1976-04-19 1976-04-19
US05/684,150 US4020097A (en) 1975-08-13 1976-05-07 Bicyclo [3.1.0]hexane-3-one derivatives of 11-deoxy PGE
US69139876A 1976-06-01 1976-06-01
US05/697,813 US4031226A (en) 1975-08-13 1976-06-21 N-[(1-piperidinyl)alkyl]arylcarboxamide derivatives
US05/764,359 US4118577A (en) 1975-08-13 1977-01-31 4,5,6-Trinor-3,7-inter-m-phenylene prostaglandin A1 analogs

Publications (1)

Publication Number Publication Date
NL7608962A true NL7608962A (nl) 1977-02-15

Family

ID=27578881

Family Applications (2)

Application Number Title Priority Date Filing Date
NL7608823A NL7608823A (nl) 1975-08-13 1976-08-09 Werkwijze ter bereiding van een optisch actieve verbinding.
NL7608962A NL7608962A (nl) 1975-08-13 1976-08-12 Werkwijze voor de bereiding van nieuwe n-((1-piperidinyl)alkyl)arylcarbonamidederivaten.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
NL7608823A NL7608823A (nl) 1975-08-13 1976-08-09 Werkwijze ter bereiding van een optisch actieve verbinding.

Country Status (11)

Country Link
US (4) US4048058A (nl)
JP (1) JPS6029384B2 (nl)
AU (1) AU1676276A (nl)
BE (2) BE845110A (nl)
CH (1) CH626337A5 (nl)
DE (2) DE2635838A1 (nl)
FR (2) FR2320754A1 (nl)
GB (2) GB1505442A (nl)
LU (1) LU75547A1 (nl)
NL (2) NL7608823A (nl)
SE (3) SE432928B (nl)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4124491A (en) * 1972-05-09 1978-11-07 Uop Inc. Hydrocarbon conversion with a selectively sulfided acidic multimetallic catalytic composite
US4096336A (en) * 1976-03-29 1978-06-20 Miles Laboratories, Inc. 5,6-Benzo analogues or prostaglandin E
US4238623A (en) * 1976-03-29 1980-12-09 Miles Laboratories, Inc. 5,6-Benzo analogues of prostaglandin
US4200641A (en) * 1976-12-21 1980-04-29 Janssen Pharmaceutica, N.V. 1-[(Heterocyclyl)-alkyl]-4-diarylmethoxy piperidine derivatives
US4082755A (en) * 1977-02-14 1978-04-04 Janssen Pharmaceutica N.V. 1-[(Diarylmethyl)aminoalkyl]piperidimes
FR2413127A1 (fr) * 1978-01-02 1979-07-27 Inst Francais Du Petrole Procede de preparation d'un catalyseur de metal noble du groupe viii presentant une resistance amelioree au soufre, catalyseur obtenu et son utilisation pour l'hydrogenation d'hydrocarbures aromatiques
JPS54160371A (en) * 1978-06-02 1979-12-19 Kyowa Hakko Kogyo Co Ltd Novel piperidine derivative and hypotensive agents comprising it
GR73633B (nl) * 1980-03-10 1984-03-26 Janssen Pharmaceutica Nv
EP0036048A1 (en) * 1980-03-13 1981-09-23 Exxon Research And Engineering Company Startup method for a hydrocarbon reforming process utilizing a bed containing an iridium component and a platinum group component reforming catalyst having a substantially uniform sulfur distribution throughout the bed
US4416806A (en) * 1981-04-10 1983-11-22 Elf France Catalyst for production of aromatic hydrocarbons and process for preparation
US4443330A (en) * 1981-06-01 1984-04-17 Hri, Inc. Catalyst activity in coal liquid upgrading
US4658033A (en) * 1985-09-23 1987-04-14 Iowa State University Research Foundation, Inc. Synthesis of interphenylene prostaglandin analogs
US4804457A (en) * 1987-07-22 1989-02-14 Shell Oil Company Process for removal of polynuclear aromatics from a hydrocarbon in an endothermic reformer reaction system
AT388731B (de) * 1987-12-15 1989-08-25 Gerot Pharmazeutika Neue derivate von benzimidazol, ihre herstellung und verwendung
FR2629368B1 (fr) * 1988-03-29 1991-01-04 Europ Retraitement Catalyse Procede de presulfuration et de controle de l'activite de catalyseur de traitement d'hydrocarbures
FR2630025B1 (fr) * 1988-04-19 1990-08-24 Inst Francais Du Petrole Procede de presulfuration de catalyseur de traitement d'hydrocarbures
FR2631562B1 (fr) * 1988-05-19 1990-09-07 Inst Francais Du Petrole Composition catalytique comprenant un sulfure metallique en suspension dans un liquide contenant des asphaltenes
FR2631631B1 (fr) * 1988-05-19 1990-09-07 Inst Francais Du Petrole Procede d'hydroviscoreduction d'une charge d'hydrocarbures en presence d'une composition catalytique comprenant un sulfure metallique en suspension dans un liquide contenant des asphaltenes
EP0343045B1 (fr) * 1988-05-19 1992-07-15 Institut Français du Pétrole Composition catalytique comprenant un sulfure métallique en suspension dans un liquide contenant des asphaltènes et procédé d'hydroviscoreduction d'une charge d'hydrocarbures
DE68903146T2 (de) * 1988-07-29 1993-04-08 Akzo Nv Verfahren fuer die herstellung eines vorsulfidierten katalysators, verfahren fuer die herstellung eines sulfidierten katalysators und verwendung dieses katalysators.
JPH0730064B2 (ja) * 1989-08-17 1995-04-05 協和醗酵工業株式会社 フラン誘導体
EP0916346A3 (en) 1991-09-20 2000-12-06 Glaxo Group Limited NK-1 receptor antagonists and 5HT3 receptor antagonists for the treatment of emesis
GB9305718D0 (en) * 1993-03-19 1993-05-05 Glaxo Group Ltd Medicaments
DE4319039A1 (de) * 1993-06-08 1994-12-15 Bayer Ag Substituierte (2-Oxo-1-benzimidazolinyl)-piperidine, Verfahren zu ihrer Herstellung und Verwendung als anti-retrovirale Mittel
FR2725381B1 (fr) * 1994-10-07 1996-12-13 Eurecat Europ Retrait Catalys Procede de pretraitement hors site d'un catalyseur de traitement d'hydrocarbures
US5661163A (en) 1995-06-07 1997-08-26 Merck & Co., Inc. Alpha-1a adrenergic receptor antagonists
US5661178A (en) * 1995-09-01 1997-08-26 Allergan Method for effecting vasodilation with (1,5-inter)aryl prostaglandin derivatives
AU2388697A (en) * 1996-04-19 1997-11-12 Neurosearch A/S 1-(4-piperidyl)-benzimidazoles having neurotrophic activity
US6340681B1 (en) * 1999-07-16 2002-01-22 Pfizer Inc 2-benzimidazolylamine compounds as ORL-1-receptor agonists
DE19952146A1 (de) * 1999-10-29 2001-06-07 Boehringer Ingelheim Pharma Arylalkane, Arylalkene und Aryl-azaalkane, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung
US6800353B1 (en) * 2000-09-08 2004-10-05 Ecolab Inc. Scratch-resistant strippable finish
EP1205855A3 (en) * 2000-11-10 2006-01-25 Masae Yanagi Data managing method, data managing system, data managing apparatus, data handling apparatus, computer program, and recording medium
DE60234057D1 (de) 2001-07-25 2009-11-26 Raptor Pharmaceutical Inc Zusammensetzungen und verfahren zur modulation des transports durch die blut-hirn-schranke
CN103259027A (zh) 2005-04-28 2013-08-21 普罗透斯数字保健公司 药物信息系统
GB0526042D0 (en) * 2005-12-21 2006-02-01 Syngenta Participations Ag Chemical compounds
US7439206B2 (en) * 2006-07-18 2008-10-21 Conocophillips Company Process for selective oxidation of carbon monoxide in a hydrogen containing stream
KR20090071598A (ko) 2006-09-18 2009-07-01 랩터 파마슈티컬 인코포레이티드 수용체 결합 단백질(ｒａｐ)-접합체 투여에 의한 간 질환의 치료
WO2009034028A2 (de) * 2007-09-07 2009-03-19 Boehringer Ingelheim International Gmbh Neue verbindungen
PT2398500T (pt) 2009-02-20 2019-06-14 2 Bbb Medicines B V Sistema de entrega de medicamentos à base de glutationas
TWI556839B (zh) 2009-05-06 2016-11-11 研究室護膚股份有限公司 包含活性劑－磷酸鈣粒子複合物之皮膚遞送組成物及其使用方法
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates
WO2014102594A2 (en) 2012-12-27 2014-07-03 Purdue Pharma L.P. Substituted benzimidazole-type piperidine compounds and uses thereof

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE541498A (nl) * 1954-09-24
US3238216A (en) * 1963-06-20 1966-03-01 Res Lab Dr C Janssen N V Substituted 1, 3, 8-triaza-spiro (4, 5) decanes
US3296119A (en) * 1964-01-08 1967-01-03 Universal Oil Prod Co Catalytic reforming process and catalyst therefor
US3342826A (en) * 1964-01-13 1967-09-19 Ile De France Heterocyclic aminoalkyl benzamides
GB1141664A (en) * 1965-12-08 1969-01-29 Janssen Pharmaceutica Nv Piperidine derivatives
US3441500A (en) * 1966-08-04 1969-04-29 Sinclair Research Inc Process for activating a fixed bed of hydrorefining catalyst
US3477963A (en) * 1966-12-20 1969-11-11 Sun Oil Co Carbon disulfide sulfiding of catalysts
US3442796A (en) * 1968-05-24 1969-05-06 Universal Oil Prod Co Continuous low pressure reforming process with a prereduced and presulfided catalyst
US3801498A (en) * 1969-03-17 1974-04-02 Universal Oil Prod Co Tetrametallic hydrocarbon conversion catalyst and uses thereof
US3617520A (en) * 1969-06-25 1971-11-02 Chevron Res Sulfiding of low platinum content catalyst
CA925454A (en) * 1969-12-08 1973-05-01 D. Keith Carl Catalytic reforming of gasoline boiling range hydrocarbons
US3915894A (en) * 1971-10-22 1975-10-28 Nalco Chemical Co Activation of hydrotreating catalysts
US3725249A (en) * 1971-12-14 1973-04-03 Universal Oil Prod Co Continuous reforming-regeneration process
US3933899A (en) * 1972-10-30 1976-01-20 The Upjohn Company PGE2 -oxa-phenylene compounds
US3933898A (en) * 1972-10-30 1976-01-20 The Upjohn Company PGE1 -oxa phenylene compounds
US3933895A (en) * 1972-10-30 1976-01-20 The Upjohn Company Oxa-phenylene compounds
US3944595A (en) * 1972-10-30 1976-03-16 The Upjohn Company PGF1.sub.α -oxaphenylene compounds
JPS49101383A (nl) * 1973-02-05 1974-09-25
US3897328A (en) * 1973-10-29 1975-07-29 Exxon Research Engineering Co Iridium-containing reforming catalyst and use thereof
US3933622A (en) * 1973-12-04 1976-01-20 Exxon Research And Engineering Company Trimetallic hydrocarbon conversion catalyst
AU502731B2 (en) * 1975-09-17 1979-08-09 The Upjohn Company Prostaglandin analogues
US4122282A (en) * 1975-12-29 1978-10-24 The Upjohn Company 2-Decarboxy-2-carboxyamino-methyl-PGFα compounds
US4055602A (en) * 1976-01-08 1977-10-25 The Upjohn Company 2-Decarboxy-2-hydroxy-methyl-5-oxa-17-phenyl-18,19,20-trinor-PGF-analogs
GB1554045A (en) * 1976-02-13 1979-10-17 Upjohn Co 13,14-didehydroprostaglandins

Also Published As

Publication number Publication date
NL7608823A (nl) 1977-02-15
FR2353290A1 (fr) 1977-12-30
SE8104871L (sv) 1981-08-17
LU75547A1 (nl) 1977-03-25
GB1552199A (en) 1979-09-12
US4031226A (en) 1977-06-21
FR2353290B1 (fr) 1985-11-15
FR2320754B1 (nl) 1979-05-25
SE7608840L (sv) 1977-02-14
GB1505442A (en) 1978-03-30
BE845110A (nl) 1977-02-14
SE7609024L (sv) 1977-02-14
DE2636614A1 (de) 1977-02-24
BE845179A (fr) 1977-02-14
US4020097A (en) 1977-04-26
US4048058A (en) 1977-09-13
DE2636614C2 (nl) 1988-04-07
SE432928B (sv) 1984-04-30
US4118577A (en) 1978-10-03
JPS5223064A (en) 1977-02-21
AU1676276A (en) 1978-02-16
JPS6029384B2 (ja) 1985-07-10
DE2635838A1 (de) 1977-02-24
CH626337A5 (nl) 1981-11-13
FR2320754A1 (fr) 1977-03-11

Similar Documents

Publication Publication Date Title
NL7608962A (nl) Werkwijze voor de bereiding van nieuwe n-((1-piperidinyl)alkyl)arylcarbonamidederivaten.
NL7602834A (nl) Werkwijze voor de bereiding van nieuwe chinolon- derivaten.
BE837831A (nl) Werkwijze voor de bereiding van nieuwe imidazoolderivaten
NL7609439A (nl) Werkwijze voor de bereiding van nieuwe heterocyclische verbindingen.
NL7611415A (nl) Werkwijze voor de bereiding van nieuwe pyrimidinonderivaten.
NL7605387A (nl) Werkwijze voor de bereiding van n-(perfluoracyl)- -n-fosfonomethylglycineverbindingen.
NL7613425A (nl) Werkwijze voor de bereiding van nieuwe imidazool- derivaten.
NL7608023A (nl) Werkwijze voor de bereiding van nieuwe 1-(benza- zolylalkyl) piperidinederivaten.
NL7703503A (nl) Werkwijze voor de bereiding van nieuwe prostag- landine derivaten.
NL7514381A (nl) Werkwijze voor de bereiding van nieuwe imidazool- derivaten.
NL7610059A (nl) Werkwijze voor de bereiding van 4-oxo-4h-benzo- pyranderivaten.
NL7604833A (nl) Werkwijze voor de bereiding van nieuwe 1-gesub- stitueerde 4-aroyl-4-hydroxypiperidinen.
NL7610513A (nl) Werkwijze voor de bereiding van nieuwe n-aryl-n-(1-l-4-piperidinyl)arylaceetamiden.
NL7609485A (nl) Werkwijze voor de bereiding van nieuwe n-tetra- hydrofurfuryl-noroxymorfonen.
NL7602192A (nl) Werkwijze voor de bereiding van nieuwe gesubsti- tueerde piperazinyliminorifamycinen.
NL7612031A (nl) Werkwijze voor de bereiding van nieuwe chinoline- derivaten.
NL7608902A (nl) Werkwijze voor de bereiding van nieuwe indoolderivaten.
NL7609020A (nl) Werkwijze voor de bereiding van nieuwe cefalosporinederivaten.
NL7709736A (nl) Nieuwe werkwijze voor de bereiding van chinazo- line-derivaten.
NL7712431A (nl) Werkwijze voor de bereiding van nieuwe norbornaanderivaten.
NL7608796A (nl) Werkwijze voor de bereiding van oxyranderivaten.
NL7611722A (nl) Werkwijze voor de bereiding van nieuwe stilbeen- derivaten.
NL7705939A (nl) Nieuwe werkwijze voor de bereiding van gesubsti- tueerde aminochinazolinederivaten.
NL7604332A (nl) Werkwijze voor de bereiding van nieuwe thiadiazool-derivaten.
NL7511696A (nl) Werkwijze voor de bereiding van monochloor-s-tria- zine derivaten.

Legal Events

Date Code Title Description
BV The patent application has lapsed