BE845179A - Nouveaux analogues de prostaglandines, leur procede de preparation et medicament les contenant - Google Patents
Nouveaux analogues de prostaglandines, leur procede de preparation et medicament les contenantInfo
- Publication number
- BE845179A BE845179A BE169803A BE169803A BE845179A BE 845179 A BE845179 A BE 845179A BE 169803 A BE169803 A BE 169803A BE 169803 A BE169803 A BE 169803A BE 845179 A BE845179 A BE 845179A
- Authority
- BE
- Belgium
- Prior art keywords
- preparation process
- product containing
- medicinal product
- prostaglandin analogues
- new prostaglandin
- Prior art date
Links
- 229940006138 antiglaucoma drug and miotics prostaglandin analogues Drugs 0.000 title 1
- 229940126601 medicinal product Drugs 0.000 title 1
- 238000002360 preparation method Methods 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J37/00—Processes, in general, for preparing catalysts; Processes, in general, for activation of catalysts
- B01J37/20—Sulfiding
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
- C07C405/0016—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing only hydroxy, etherified or esterified hydroxy groups
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
- C07C51/377—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by splitting-off hydrogen or functional groups; by hydrogenolysis of functional groups
- C07C51/38—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by splitting-off hydrogen or functional groups; by hydrogenolysis of functional groups by decarboxylation
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D203/00—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom
- C07D203/04—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D203/06—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D203/16—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with acylated ring nitrogen atoms
- C07D203/18—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with acylated ring nitrogen atoms by carboxylic acids, or by sulfur or nitrogen analogues thereof
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/44—Oxygen atoms attached in position 4
- C07D211/52—Oxygen atoms attached in position 4 having an aryl radical as the second substituent in position 4
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/56—Nitrogen atoms
- C07D211/58—Nitrogen atoms attached in position 4
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/04—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
- C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/10—Oxygen atoms
- C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
- C07D319/06—1,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
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- C—CHEMISTRY; METALLURGY
- C10—PETROLEUM, GAS OR COKE INDUSTRIES; TECHNICAL GASES CONTAINING CARBON MONOXIDE; FUELS; LUBRICANTS; PEAT
- C10G—CRACKING HYDROCARBON OILS; PRODUCTION OF LIQUID HYDROCARBON MIXTURES, e.g. BY DESTRUCTIVE HYDROGENATION, OLIGOMERISATION, POLYMERISATION; RECOVERY OF HYDROCARBON OILS FROM OIL-SHALE, OIL-SAND, OR GASES; REFINING MIXTURES MAINLY CONSISTING OF HYDROCARBONS; REFORMING OF NAPHTHA; MINERAL WAXES
- C10G35/00—Reforming naphtha
- C10G35/22—Starting-up reforming operations
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- General Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Materials Engineering (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Epoxy Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Production Of Liquid Hydrocarbon Mixture For Refining Petroleum (AREA)
- Catalysts (AREA)
Applications Claiming Priority (9)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US60428275A | 1975-08-13 | 1975-08-13 | |
US60415875A | 1975-08-13 | 1975-08-13 | |
US05/604,159 US3997566A (en) | 1975-02-24 | 1975-08-13 | Tricyclic prostaglandin |
US05/621,047 US4048058A (en) | 1975-08-13 | 1975-10-09 | Methods to be used in reforming processes employing multi-metallic catalysts |
US67787476A | 1976-04-19 | 1976-04-19 | |
US05/684,150 US4020097A (en) | 1975-08-13 | 1976-05-07 | Bicyclo [3.1.0]hexane-3-one derivatives of 11-deoxy PGE |
US69139876A | 1976-06-01 | 1976-06-01 | |
US05/697,813 US4031226A (en) | 1975-08-13 | 1976-06-21 | N-[(1-piperidinyl)alkyl]arylcarboxamide derivatives |
US05/764,359 US4118577A (en) | 1975-08-13 | 1977-01-31 | 4,5,6-Trinor-3,7-inter-m-phenylene prostaglandin A1 analogs |
Publications (1)
Publication Number | Publication Date |
---|---|
BE845179A true BE845179A (fr) | 1977-02-14 |
Family
ID=27578881
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BE169743A BE845110A (nl) | 1975-08-13 | 1976-08-12 | Werkwijze voor de bereiding van nieuwe n-((1-piperidinyl)alkyl) arylcarbonamidederivaten |
BE169803A BE845179A (fr) | 1975-08-13 | 1976-08-13 | Nouveaux analogues de prostaglandines, leur procede de preparation et medicament les contenant |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BE169743A BE845110A (nl) | 1975-08-13 | 1976-08-12 | Werkwijze voor de bereiding van nieuwe n-((1-piperidinyl)alkyl) arylcarbonamidederivaten |
Country Status (11)
Country | Link |
---|---|
US (4) | US4048058A (fr) |
JP (1) | JPS6029384B2 (fr) |
AU (1) | AU1676276A (fr) |
BE (2) | BE845110A (fr) |
CH (1) | CH626337A5 (fr) |
DE (2) | DE2635838A1 (fr) |
FR (2) | FR2320754A1 (fr) |
GB (2) | GB1505442A (fr) |
LU (1) | LU75547A1 (fr) |
NL (2) | NL7608823A (fr) |
SE (3) | SE432928B (fr) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4096336A (en) * | 1976-03-29 | 1978-06-20 | Miles Laboratories, Inc. | 5,6-Benzo analogues or prostaglandin E |
US4097516A (en) * | 1976-03-29 | 1978-06-27 | Miles Laboratories, Inc. | 5,6-Benzo analogues of prostaglandin E |
Families Citing this family (40)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4124491A (en) * | 1972-05-09 | 1978-11-07 | Uop Inc. | Hydrocarbon conversion with a selectively sulfided acidic multimetallic catalytic composite |
US4200641A (en) * | 1976-12-21 | 1980-04-29 | Janssen Pharmaceutica, N.V. | 1-[(Heterocyclyl)-alkyl]-4-diarylmethoxy piperidine derivatives |
US4082755A (en) * | 1977-02-14 | 1978-04-04 | Janssen Pharmaceutica N.V. | 1-[(Diarylmethyl)aminoalkyl]piperidimes |
FR2413127A1 (fr) * | 1978-01-02 | 1979-07-27 | Inst Francais Du Petrole | Procede de preparation d'un catalyseur de metal noble du groupe viii presentant une resistance amelioree au soufre, catalyseur obtenu et son utilisation pour l'hydrogenation d'hydrocarbures aromatiques |
JPS54160371A (en) * | 1978-06-02 | 1979-12-19 | Kyowa Hakko Kogyo Co Ltd | Novel piperidine derivative and hypotensive agents comprising it |
GR73633B (fr) * | 1980-03-10 | 1984-03-26 | Janssen Pharmaceutica Nv | |
EP0036048A1 (fr) * | 1980-03-13 | 1981-09-23 | Exxon Research And Engineering Company | Procédé de démarrage d'un procédé de reformage d'hydrocarbures utilisant un lit contenant un catalyseur de reformage comprenant de l'iridium et un métal du groupe du platine et ayant une distribution de soufre essentiellement uniforme dans le lit |
US4416806A (en) * | 1981-04-10 | 1983-11-22 | Elf France | Catalyst for production of aromatic hydrocarbons and process for preparation |
US4443330A (en) * | 1981-06-01 | 1984-04-17 | Hri, Inc. | Catalyst activity in coal liquid upgrading |
US4658033A (en) * | 1985-09-23 | 1987-04-14 | Iowa State University Research Foundation, Inc. | Synthesis of interphenylene prostaglandin analogs |
US4804457A (en) * | 1987-07-22 | 1989-02-14 | Shell Oil Company | Process for removal of polynuclear aromatics from a hydrocarbon in an endothermic reformer reaction system |
AT388731B (de) * | 1987-12-15 | 1989-08-25 | Gerot Pharmazeutika | Neue derivate von benzimidazol, ihre herstellung und verwendung |
FR2629368B1 (fr) * | 1988-03-29 | 1991-01-04 | Europ Retraitement Catalyse | Procede de presulfuration et de controle de l'activite de catalyseur de traitement d'hydrocarbures |
FR2630025B1 (fr) * | 1988-04-19 | 1990-08-24 | Inst Francais Du Petrole | Procede de presulfuration de catalyseur de traitement d'hydrocarbures |
FR2631562B1 (fr) * | 1988-05-19 | 1990-09-07 | Inst Francais Du Petrole | Composition catalytique comprenant un sulfure metallique en suspension dans un liquide contenant des asphaltenes |
DE68902095T2 (de) * | 1988-05-19 | 1992-12-10 | Inst Francais Du Petrol | Katalytische zusammensetzung, die ein metallsulfid in form einer suspension mit einer asphalt enthaltenden fluessigkeit enthaelt und verfahren zur hydroviskoreduktion von kohlenwasserstoffen. |
FR2631631B1 (fr) * | 1988-05-19 | 1990-09-07 | Inst Francais Du Petrole | Procede d'hydroviscoreduction d'une charge d'hydrocarbures en presence d'une composition catalytique comprenant un sulfure metallique en suspension dans un liquide contenant des asphaltenes |
DE68903146T2 (de) * | 1988-07-29 | 1993-04-08 | Akzo Nv | Verfahren fuer die herstellung eines vorsulfidierten katalysators, verfahren fuer die herstellung eines sulfidierten katalysators und verwendung dieses katalysators. |
JPH0730064B2 (ja) * | 1989-08-17 | 1995-04-05 | 協和醗酵工業株式会社 | フラン誘導体 |
ES2149767T5 (es) * | 1991-09-20 | 2005-06-16 | Glaxo Group Limited | Nuevo uso medico para antagonistas de taquiquininas. |
GB9305718D0 (en) * | 1993-03-19 | 1993-05-05 | Glaxo Group Ltd | Medicaments |
DE4319039A1 (de) * | 1993-06-08 | 1994-12-15 | Bayer Ag | Substituierte (2-Oxo-1-benzimidazolinyl)-piperidine, Verfahren zu ihrer Herstellung und Verwendung als anti-retrovirale Mittel |
FR2725381B1 (fr) * | 1994-10-07 | 1996-12-13 | Eurecat Europ Retrait Catalys | Procede de pretraitement hors site d'un catalyseur de traitement d'hydrocarbures |
US5661163A (en) | 1995-06-07 | 1997-08-26 | Merck & Co., Inc. | Alpha-1a adrenergic receptor antagonists |
US5661178A (en) * | 1995-09-01 | 1997-08-26 | Allergan | Method for effecting vasodilation with (1,5-inter)aryl prostaglandin derivatives |
EP0898568B1 (fr) * | 1996-04-19 | 2006-10-04 | Neurosearch A/S | 1-(4-piperidyl)-benzimidazoles presentant une activite neurotrophique |
US6340681B1 (en) * | 1999-07-16 | 2002-01-22 | Pfizer Inc | 2-benzimidazolylamine compounds as ORL-1-receptor agonists |
DE19952146A1 (de) * | 1999-10-29 | 2001-06-07 | Boehringer Ingelheim Pharma | Arylalkane, Arylalkene und Aryl-azaalkane, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung |
US6800353B1 (en) * | 2000-09-08 | 2004-10-05 | Ecolab Inc. | Scratch-resistant strippable finish |
EP1205855A3 (fr) * | 2000-11-10 | 2006-01-25 | Masae Yanagi | Méthode, système et appareil de gestion de données, appareil de manipulation de données, programme informatique et support d'enregistrement |
DE60234057D1 (de) | 2001-07-25 | 2009-11-26 | Raptor Pharmaceutical Inc | Zusammensetzungen und verfahren zur modulation des transports durch die blut-hirn-schranke |
CN103259027A (zh) | 2005-04-28 | 2013-08-21 | 普罗透斯数字保健公司 | 药物信息系统 |
GB0526042D0 (en) * | 2005-12-21 | 2006-02-01 | Syngenta Participations Ag | Chemical compounds |
US7439206B2 (en) * | 2006-07-18 | 2008-10-21 | Conocophillips Company | Process for selective oxidation of carbon monoxide in a hydrogen containing stream |
US8795627B2 (en) | 2007-03-21 | 2014-08-05 | Raptor Pharmaceuticals Inc. | Treatment of liver disorders by administration of RAP conjugates |
WO2009034028A2 (fr) * | 2007-09-07 | 2009-03-19 | Boehringer Ingelheim International Gmbh | Nouveaux composés |
EP3395372B1 (fr) | 2009-02-20 | 2022-04-06 | EnhanX Biopharm Inc. | Système d'administration de médicament à base de glutathion |
SG175896A1 (en) | 2009-05-06 | 2011-12-29 | Lab Skin Care Inc | Dermal delivery compositions comprising active agent-calcium phosphate particle complexes and methods of using the same |
US20120077778A1 (en) | 2010-09-29 | 2012-03-29 | Andrea Bourdelais | Ladder-Frame Polyether Conjugates |
WO2014102594A2 (fr) | 2012-12-27 | 2014-07-03 | Purdue Pharma L.P. | Composés de pipéridine de type benzimidazole substitué et leurs utilisations |
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IT542366A (fr) * | 1954-09-24 | |||
US3238216A (en) * | 1963-06-20 | 1966-03-01 | Res Lab Dr C Janssen N V | Substituted 1, 3, 8-triaza-spiro (4, 5) decanes |
US3296119A (en) * | 1964-01-08 | 1967-01-03 | Universal Oil Prod Co | Catalytic reforming process and catalyst therefor |
US3342826A (en) * | 1964-01-13 | 1967-09-19 | Ile De France | Heterocyclic aminoalkyl benzamides |
GB1141664A (en) * | 1965-12-08 | 1969-01-29 | Janssen Pharmaceutica Nv | Piperidine derivatives |
US3441500A (en) * | 1966-08-04 | 1969-04-29 | Sinclair Research Inc | Process for activating a fixed bed of hydrorefining catalyst |
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US3442796A (en) * | 1968-05-24 | 1969-05-06 | Universal Oil Prod Co | Continuous low pressure reforming process with a prereduced and presulfided catalyst |
US3801498A (en) * | 1969-03-17 | 1974-04-02 | Universal Oil Prod Co | Tetrametallic hydrocarbon conversion catalyst and uses thereof |
US3617520A (en) * | 1969-06-25 | 1971-11-02 | Chevron Res | Sulfiding of low platinum content catalyst |
CA925454A (en) * | 1969-12-08 | 1973-05-01 | D. Keith Carl | Catalytic reforming of gasoline boiling range hydrocarbons |
US3915894A (en) * | 1971-10-22 | 1975-10-28 | Nalco Chemical Co | Activation of hydrotreating catalysts |
US3725249A (en) * | 1971-12-14 | 1973-04-03 | Universal Oil Prod Co | Continuous reforming-regeneration process |
US3933899A (en) * | 1972-10-30 | 1976-01-20 | The Upjohn Company | PGE2 -oxa-phenylene compounds |
US3933898A (en) * | 1972-10-30 | 1976-01-20 | The Upjohn Company | PGE1 -oxa phenylene compounds |
US3944595A (en) * | 1972-10-30 | 1976-03-16 | The Upjohn Company | PGF1.sub.α -oxaphenylene compounds |
US3933895A (en) * | 1972-10-30 | 1976-01-20 | The Upjohn Company | Oxa-phenylene compounds |
JPS49101383A (fr) * | 1973-02-05 | 1974-09-25 | ||
US3897328A (en) * | 1973-10-29 | 1975-07-29 | Exxon Research Engineering Co | Iridium-containing reforming catalyst and use thereof |
US3933622A (en) * | 1973-12-04 | 1976-01-20 | Exxon Research And Engineering Company | Trimetallic hydrocarbon conversion catalyst |
AU502731B2 (en) * | 1975-09-17 | 1979-08-09 | The Upjohn Company | Prostaglandin analogues |
US4081478A (en) * | 1975-12-29 | 1978-03-28 | The Upjohn Company | 2-Decarboxy-2-amino-methyl-PGF.sub.α compounds |
US4055602A (en) * | 1976-01-08 | 1977-10-25 | The Upjohn Company | 2-Decarboxy-2-hydroxy-methyl-5-oxa-17-phenyl-18,19,20-trinor-PGF-analogs |
FR2361362B1 (fr) * | 1976-02-13 | 1986-02-21 | Upjohn Co | Analogues des prostaglandines |
-
1975
- 1975-10-09 US US05/621,047 patent/US4048058A/en not_active Expired - Lifetime
-
1976
- 1976-05-07 US US05/684,150 patent/US4020097A/en not_active Expired - Lifetime
- 1976-06-21 US US05/697,813 patent/US4031226A/en not_active Expired - Lifetime
- 1976-07-08 GB GB28440/76A patent/GB1505442A/en not_active Expired
- 1976-08-02 CH CH985976A patent/CH626337A5/de not_active IP Right Cessation
- 1976-08-04 FR FR7623844A patent/FR2320754A1/fr active Granted
- 1976-08-06 LU LU75547A patent/LU75547A1/xx unknown
- 1976-08-06 SE SE7608840A patent/SE432928B/xx unknown
- 1976-08-09 NL NL7608823A patent/NL7608823A/xx not_active Application Discontinuation
- 1976-08-10 DE DE19762635838 patent/DE2635838A1/de not_active Withdrawn
- 1976-08-11 AU AU16762/76A patent/AU1676276A/en not_active Expired
- 1976-08-12 FR FR7624701A patent/FR2353290B1/fr not_active Expired
- 1976-08-12 GB GB33622/76A patent/GB1552199A/en not_active Expired
- 1976-08-12 NL NL7608962A patent/NL7608962A/xx not_active Application Discontinuation
- 1976-08-12 JP JP51095479A patent/JPS6029384B2/ja not_active Expired
- 1976-08-12 SE SE7609024A patent/SE7609024L/xx unknown
- 1976-08-12 BE BE169743A patent/BE845110A/xx not_active IP Right Cessation
- 1976-08-13 DE DE19762636614 patent/DE2636614A1/de active Granted
- 1976-08-13 BE BE169803A patent/BE845179A/fr not_active IP Right Cessation
-
1977
- 1977-01-31 US US05/764,359 patent/US4118577A/en not_active Expired - Lifetime
-
1981
- 1981-08-17 SE SE8104871A patent/SE8104871L/sv not_active Application Discontinuation
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4096336A (en) * | 1976-03-29 | 1978-06-20 | Miles Laboratories, Inc. | 5,6-Benzo analogues or prostaglandin E |
US4097516A (en) * | 1976-03-29 | 1978-06-27 | Miles Laboratories, Inc. | 5,6-Benzo analogues of prostaglandin E |
US4100185A (en) * | 1976-03-29 | 1978-07-11 | Miles Laboratories, Inc. | Cyclohexanone 5,6-benzo analogues of prostaglandin E |
US4100352A (en) * | 1976-03-29 | 1978-07-11 | Miles Laboratories, Inc. | Cyclohexanone-5,6-benzo analogues of prostaglandin |
US4100353A (en) * | 1976-03-29 | 1978-07-11 | Miles Laboratories, Inc. | 5,6-Benza analogues of prostaglandin F |
Also Published As
Publication number | Publication date |
---|---|
GB1505442A (en) | 1978-03-30 |
SE7608840L (sv) | 1977-02-14 |
JPS5223064A (en) | 1977-02-21 |
GB1552199A (en) | 1979-09-12 |
NL7608962A (nl) | 1977-02-15 |
SE7609024L (sv) | 1977-02-14 |
SE432928B (sv) | 1984-04-30 |
BE845110A (nl) | 1977-02-14 |
DE2635838A1 (de) | 1977-02-24 |
CH626337A5 (fr) | 1981-11-13 |
US4118577A (en) | 1978-10-03 |
FR2320754A1 (fr) | 1977-03-11 |
SE8104871L (sv) | 1981-08-17 |
AU1676276A (en) | 1978-02-16 |
FR2353290A1 (fr) | 1977-12-30 |
FR2353290B1 (fr) | 1985-11-15 |
DE2636614A1 (de) | 1977-02-24 |
DE2636614C2 (fr) | 1988-04-07 |
US4048058A (en) | 1977-09-13 |
JPS6029384B2 (ja) | 1985-07-10 |
FR2320754B1 (fr) | 1979-05-25 |
LU75547A1 (fr) | 1977-03-25 |
NL7608823A (nl) | 1977-02-15 |
US4020097A (en) | 1977-04-26 |
US4031226A (en) | 1977-06-21 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RE | Patent lapsed |
Owner name: THE UPJOHN CY Effective date: 19860831 |