NL7510194A - Met technetium 99-m gemerkte radiodiagnostische middelen en werkwijze voor het bereiden daarvan alsmede werkwijze voor het bereiden van een sta- biele niet-radioactieve drager. - Google Patents
Met technetium 99-m gemerkte radiodiagnostische middelen en werkwijze voor het bereiden daarvan alsmede werkwijze voor het bereiden van een sta- biele niet-radioactieve drager.Info
- Publication number
- NL7510194A NL7510194A NL7510194A NL7510194A NL7510194A NL 7510194 A NL7510194 A NL 7510194A NL 7510194 A NL7510194 A NL 7510194A NL 7510194 A NL7510194 A NL 7510194A NL 7510194 A NL7510194 A NL 7510194A
- Authority
- NL
- Netherlands
- Prior art keywords
- preparing
- carrier
- solution
- tartrate
- albumin
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- GKLVYJBZJHMRIY-OUBTZVSYSA-N Technetium-99 Chemical compound [99Tc] GKLVYJBZJHMRIY-OUBTZVSYSA-N 0.000 title 1
- 229940056501 technetium 99m Drugs 0.000 title 1
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 abstract 3
- 102000009027 Albumins Human genes 0.000 abstract 2
- 108010088751 Albumins Proteins 0.000 abstract 2
- FEWJPZIEWOKRBE-JCYAYHJZSA-N Dextrotartaric acid Chemical compound OC(=O)[C@H](O)[C@@H](O)C(O)=O FEWJPZIEWOKRBE-JCYAYHJZSA-N 0.000 abstract 2
- 102000008100 Human Serum Albumin Human genes 0.000 abstract 2
- 108091006905 Human Serum Albumin Proteins 0.000 abstract 2
- 229910052708 sodium Inorganic materials 0.000 abstract 2
- 239000011734 sodium Substances 0.000 abstract 2
- 229940095064 tartrate Drugs 0.000 abstract 2
- YXTDAZMTQFUZHK-ZVGUSBNCSA-L (2r,3r)-2,3-dihydroxybutanedioate;tin(2+) Chemical compound [Sn+2].[O-]C(=O)[C@H](O)[C@@H](O)C([O-])=O YXTDAZMTQFUZHK-ZVGUSBNCSA-L 0.000 abstract 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 abstract 1
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 abstract 1
- ATJFFYVFTNAWJD-UHFFFAOYSA-N Tin Chemical compound [Sn] ATJFFYVFTNAWJD-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000002245 particle Substances 0.000 abstract 1
- 239000003755 preservative agent Substances 0.000 abstract 1
- 230000002335 preservative effect Effects 0.000 abstract 1
- 125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 abstract 1
- 230000002285 radioactive effect Effects 0.000 abstract 1
- 229940007163 stannous tartrate Drugs 0.000 abstract 1
- IUTCEZPPWBHGIX-UHFFFAOYSA-N tin(2+) Chemical compound [Sn+2] IUTCEZPPWBHGIX-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/081—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins the protein being an albumin, e.g. human serum albumin [HSA], bovine serum albumin [BSA], ovalbumin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
- A61K51/1217—Dispersions, suspensions, colloids, emulsions, e.g. perfluorinated emulsion, sols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
- A61K51/1241—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules particles, powders, lyophilizates, adsorbates, e.g. polymers or resins for adsorption or ion-exchange resins
- A61K51/1255—Granulates, agglomerates, microspheres
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2123/00—Preparations for testing in vivo
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Optics & Photonics (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Physics & Mathematics (AREA)
- Public Health (AREA)
- Dispersion Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/501,704 US3987157A (en) | 1974-08-29 | 1974-08-29 | Technetium 99-m labeled radio-diagnostic agents employing stannous tartrate and method of preparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NL7510194A true NL7510194A (nl) | 1976-03-02 |
Family
ID=23994693
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NL7510194A NL7510194A (nl) | 1974-08-29 | 1975-08-28 | Met technetium 99-m gemerkte radiodiagnostische middelen en werkwijze voor het bereiden daarvan alsmede werkwijze voor het bereiden van een sta- biele niet-radioactieve drager. |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US3987157A (enExample) |
| JP (2) | JPS5151526A (enExample) |
| CA (1) | CA1058518A (enExample) |
| DE (1) | DE2538388C3 (enExample) |
| FR (2) | FR2282909A1 (enExample) |
| GB (2) | GB1508900A (enExample) |
| NL (1) | NL7510194A (enExample) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4054645A (en) * | 1976-08-24 | 1977-10-18 | Minnesota Mining And Manufacturing Company | Radiodiagnostic complexes employing fluorine-containing tin reducing agents |
| US4233284A (en) * | 1978-03-31 | 1980-11-11 | The Procter & Gamble Company | Stabilized radiographic scanning agents |
| GB2042887B (en) * | 1979-02-22 | 1983-10-12 | New England Nuclear Corp | Albumin microaggregates for radioactive scanning of reticuloendothelial systems |
| DE3071968D1 (en) * | 1980-08-11 | 1987-06-19 | Du Pont | Denatured albumin complexes for radioscintigraphic imaging and evaluation of reticuloendothelial systems |
| JPS5750928A (en) * | 1980-09-13 | 1982-03-25 | Nippon Mejifuijitsukusu Kk | Diagnostic agent for scanning bone |
| US4406876A (en) * | 1980-10-14 | 1983-09-27 | Research Foundation Of The State Univ. Of New York | Sulfur free small-particle production of technetium sulfur colloid |
| US4455291A (en) * | 1982-01-22 | 1984-06-19 | New England Nuclear Corporation | Accelerators for forming cationic technetium complexes useful as radiodiagnostic agents |
| IT1201087B (it) * | 1982-04-15 | 1989-01-27 | Gentili Ist Spa | Bifosfonati farmacologicamente attivi,procedimento per la loro preparazione e relative composizioni farmaceutiche |
| JPS58163606U (ja) * | 1982-04-27 | 1983-10-31 | 「と」 協意 | ボイラによる動力発生装置 |
| US4374821A (en) * | 1982-06-28 | 1983-02-22 | E. R. Squibb & Sons, Inc. | Myocardial imaging agent and method |
| US4673562A (en) * | 1983-08-19 | 1987-06-16 | The Children's Medical Center Corporation | Bisamide bisthiol compounds useful for making technetium radiodiagnostic renal agents |
| US4582700A (en) * | 1983-09-01 | 1986-04-15 | Mallinckrodt, Inc. | Products and processes |
| US4610391A (en) * | 1984-12-18 | 1986-09-09 | Union Carbide Corporation | Process for wave soldering |
| US4897255A (en) * | 1985-01-14 | 1990-01-30 | Neorx Corporation | Metal radionuclide labeled proteins for diagnosis and therapy |
| US5175343A (en) * | 1985-01-14 | 1992-12-29 | Neorx Corporation | Metal radionuclide labeled proteins for diagnosis and therapy |
| US5164175A (en) * | 1986-12-10 | 1992-11-17 | Hoechst Aktiengesellschaft | Diagnostic aid containing an organ-specific substance labeled with technetium-99m |
| US5202109A (en) * | 1988-06-10 | 1993-04-13 | Neorx Corporation | Conjugates for bone imaging and bone cancer therapy |
| US5089249A (en) * | 1988-06-10 | 1992-02-18 | Neorx Corporation | Conjugates for bone imaging and bone cancer therapy |
| FI920459L (fi) * | 1991-02-05 | 1992-08-06 | Hoechst Ag | Foerfarande foer framstaellning av ett med teknetium-99m maerkt organspecifikt aemne. |
| US5306482A (en) * | 1991-04-09 | 1994-04-26 | Merck Frosst Canada, Inc. | Radiopharmaceutical bacteriostats |
| US6730286B2 (en) | 2001-02-28 | 2004-05-04 | Bracco Diagnostics, Inc. | Manufacturing process to control particle size |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE786566A (fr) * | 1971-07-20 | 1973-01-22 | Squibb & Sons Inc | Agregats a base de tc-99m et d'albumine |
| US3863004A (en) * | 1972-03-20 | 1975-01-28 | Mallinckrodt Chemical Works | Denatured macroprotein with divalent tin for tagging with technetium-99m and method of preparation |
| US3735001A (en) * | 1972-05-24 | 1973-05-22 | Atomic Energy Commission | Technetium bone scanning medium |
| FR2187314B1 (enExample) * | 1972-06-06 | 1975-06-20 | Commissariat Energie Atomique | |
| US3852414A (en) * | 1972-09-13 | 1974-12-03 | New England Nuclear Corp | Bone seeking technetium 99m stannous phosphate complex |
| CA1027135A (en) * | 1973-06-11 | 1978-02-28 | Research Corporation | Bone-seeking technetium-99m complex |
-
1974
- 1974-08-29 US US05/501,704 patent/US3987157A/en not_active Expired - Lifetime
-
1975
- 1975-07-31 CA CA232,595A patent/CA1058518A/en not_active Expired
- 1975-08-28 DE DE2538388A patent/DE2538388C3/de not_active Expired
- 1975-08-28 GB GB12642/76A patent/GB1508900A/en not_active Expired
- 1975-08-28 JP JP50103546A patent/JPS5151526A/ja active Pending
- 1975-08-28 NL NL7510194A patent/NL7510194A/xx not_active Application Discontinuation
- 1975-08-28 FR FR7526562A patent/FR2282909A1/fr active Granted
- 1975-08-28 GB GB35534/75A patent/GB1508899A/en not_active Expired
-
1977
- 1977-11-03 FR FR7733013A patent/FR2366021A1/fr not_active Withdrawn
-
1978
- 1978-04-11 JP JP4181778A patent/JPS542343A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JPS542343A (en) | 1979-01-09 |
| DE2538388A1 (de) | 1976-03-11 |
| FR2282909A1 (fr) | 1976-03-26 |
| FR2366021A1 (fr) | 1978-04-28 |
| DE2538388B2 (de) | 1978-10-26 |
| US3987157A (en) | 1976-10-19 |
| GB1508900A (en) | 1978-04-26 |
| GB1508899A (en) | 1978-04-26 |
| FR2282909B1 (enExample) | 1979-05-25 |
| DE2538388C3 (de) | 1979-06-28 |
| CA1058518A (en) | 1979-07-17 |
| JPS5151526A (en) | 1976-05-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| BV | The patent application has lapsed |