NL7509075A - Werkwijze voor de bereiding van nieuwe 17(alpha),21- -diesters van 17(alpha),21-dihydroxysteroiden uit de pregnaanreeks. - Google Patents

Werkwijze voor de bereiding van nieuwe 17(alpha),21- -diesters van 17(alpha),21-dihydroxysteroiden uit de pregnaanreeks.

Info

Publication number
NL7509075A
NL7509075A NL7509075A NL7509075A NL7509075A NL 7509075 A NL7509075 A NL 7509075A NL 7509075 A NL7509075 A NL 7509075A NL 7509075 A NL7509075 A NL 7509075A NL 7509075 A NL7509075 A NL 7509075A
Authority
NL
Netherlands
Prior art keywords
alpha
dihydroxysteroids
diesters
preparation
new
Prior art date
Application number
NL7509075A
Other languages
English (en)
Dutch (nl)
Original Assignee
Glaxo Lab Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Lab Ltd filed Critical Glaxo Lab Ltd
Publication of NL7509075A publication Critical patent/NL7509075A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0088Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 containing unsubstituted amino radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J43/00Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J5/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0061Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16
    • C07J5/0069Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group
    • C07J5/0076Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group by an alkyl group

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NL7509075A 1974-07-31 1975-07-30 Werkwijze voor de bereiding van nieuwe 17(alpha),21- -diesters van 17(alpha),21-dihydroxysteroiden uit de pregnaanreeks. NL7509075A (nl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB33786/74A GB1516095A (en) 1974-07-31 1974-07-31 17,21-diesters of 17alpha,21-dihydroxy-steroids of the pregnane series

Publications (1)

Publication Number Publication Date
NL7509075A true NL7509075A (nl) 1976-02-03

Family

ID=10357423

Family Applications (1)

Application Number Title Priority Date Filing Date
NL7509075A NL7509075A (nl) 1974-07-31 1975-07-30 Werkwijze voor de bereiding van nieuwe 17(alpha),21- -diesters van 17(alpha),21-dihydroxysteroiden uit de pregnaanreeks.

Country Status (13)

Country Link
JP (1) JPS51125059A (hu)
BE (1) BE831931A (hu)
CA (1) CA1058610A (hu)
CH (1) CH615442A5 (hu)
DE (1) DE2534051A1 (hu)
DK (1) DK139303B (hu)
ES (1) ES439852A1 (hu)
FR (1) FR2280383A1 (hu)
GB (1) GB1516095A (hu)
IE (1) IE42124B1 (hu)
NL (1) NL7509075A (hu)
SE (1) SE7508654L (hu)
ZA (1) ZA754907B (hu)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4456602A (en) * 1982-08-23 1984-06-26 The Upjohn Company Amine containing ester prodrugs of corticosteroids
US4443440A (en) * 1982-08-30 1984-04-17 The Upjohn Company Amine containing ester prodrugs of corticosteroids
FR2600653B1 (fr) * 1986-06-24 1988-12-16 Pasteur Strasbourg Universite Composes de synthese associative d'acides amines soufres ou non soufres avec des derives du d-4 pregnene 3,20-dione ou avec des derives du d-1,4 pregnadiene 3,20-dione aux proprietes glucocorticoides et anti-inflammatoires, procedes d'obtention, compositions pharmaceutiques les contenant. proprietes pharmacologiques et applications
DE4333920A1 (de) 1993-10-05 1995-04-13 Hoechst Ag Corticoid-17,21-dicarbonsäureester sowie Corticosteroid-17-carbonsäureester-21-kohlensäureester, Verfahren zu deren Herstellung und diese enthaltende Arzneimittel

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1044212B (it) * 1971-03-17 1980-03-20 Sigma Tau Ind Farmaceuti Esteri del besametazone e betametazone
GB1440063A (en) * 1972-08-11 1976-06-23 Glaxo Lab Ltd 17alpha-esters of 17alpha,21-dihydroxy-20-oxo-steroids

Also Published As

Publication number Publication date
CA1058610A (en) 1979-07-17
BE831931A (fr) 1976-01-30
ES439852A1 (es) 1977-03-01
JPS51125059A (en) 1976-11-01
DE2534051A1 (de) 1976-02-19
IE42124B1 (en) 1980-06-04
CH615442A5 (en) 1980-01-31
DK139303B (da) 1979-01-29
DK346975A (hu) 1976-02-01
SE7508654L (sv) 1976-02-02
ZA754907B (en) 1976-07-28
GB1516095A (en) 1978-06-28
FR2280383A1 (fr) 1976-02-27
AU8353175A (en) 1977-02-03
DK139303C (hu) 1979-08-06
FR2280383B1 (hu) 1978-10-06
IE42124L (en) 1976-01-31

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Legal Events

Date Code Title Description
BV The patent application has lapsed