NL7509075A - PROCESS FOR PREPARATION OF NEW 17 (ALPHA), 21 DIESTERS OF 17 (ALPHA), 21 DIHYDROXYSTEROIDS FROM THE PREGNAN SERIES. - Google Patents

PROCESS FOR PREPARATION OF NEW 17 (ALPHA), 21 DIESTERS OF 17 (ALPHA), 21 DIHYDROXYSTEROIDS FROM THE PREGNAN SERIES.

Info

Publication number
NL7509075A
NL7509075A NL7509075A NL7509075A NL7509075A NL 7509075 A NL7509075 A NL 7509075A NL 7509075 A NL7509075 A NL 7509075A NL 7509075 A NL7509075 A NL 7509075A NL 7509075 A NL7509075 A NL 7509075A
Authority
NL
Netherlands
Prior art keywords
alpha
dihydroxysteroids
diesters
preparation
new
Prior art date
Application number
NL7509075A
Other languages
Dutch (nl)
Original Assignee
Glaxo Lab Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Lab Ltd filed Critical Glaxo Lab Ltd
Publication of NL7509075A publication Critical patent/NL7509075A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0088—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 containing unsubstituted amino radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0061—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16
    • C07J5/0069—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group
    • C07J5/0076—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group by an alkyl group

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NL7509075A 1974-07-31 1975-07-30 PROCESS FOR PREPARATION OF NEW 17 (ALPHA), 21 DIESTERS OF 17 (ALPHA), 21 DIHYDROXYSTEROIDS FROM THE PREGNAN SERIES. NL7509075A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB33786/74A GB1516095A (en) 1974-07-31 1974-07-31 17,21-diesters of 17alpha,21-dihydroxy-steroids of the pregnane series

Publications (1)

Publication Number Publication Date
NL7509075A true NL7509075A (en) 1976-02-03

Family

ID=10357423

Family Applications (1)

Application Number Title Priority Date Filing Date
NL7509075A NL7509075A (en) 1974-07-31 1975-07-30 PROCESS FOR PREPARATION OF NEW 17 (ALPHA), 21 DIESTERS OF 17 (ALPHA), 21 DIHYDROXYSTEROIDS FROM THE PREGNAN SERIES.

Country Status (13)

Country Link
JP (1) JPS51125059A (en)
BE (1) BE831931A (en)
CA (1) CA1058610A (en)
CH (1) CH615442A5 (en)
DE (1) DE2534051A1 (en)
DK (1) DK139303B (en)
ES (1) ES439852A1 (en)
FR (1) FR2280383A1 (en)
GB (1) GB1516095A (en)
IE (1) IE42124B1 (en)
NL (1) NL7509075A (en)
SE (1) SE7508654L (en)
ZA (1) ZA754907B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4456602A (en) * 1982-08-23 1984-06-26 The Upjohn Company Amine containing ester prodrugs of corticosteroids
US4443440A (en) * 1982-08-30 1984-04-17 The Upjohn Company Amine containing ester prodrugs of corticosteroids
FR2600653B1 (en) * 1986-06-24 1988-12-16 Pasteur Strasbourg Universite COMPOUNDS FOR ASSOCIATIVE SYNTHESIS OF SULFUR OR NON-SULFUR AMINO ACIDS WITH D-4 PREGNENE 3,20-DIONE DERIVATIVES OR WITH D-1,4 PREGNADIENE 3,20-DIONE DERIVATIVES WITH GLUCOCORTICOID AND ANTI-INFLAMMATORY PROPERTIES, METHODS OBTAINED, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM. PHARMACOLOGICAL PROPERTIES AND APPLICATIONS
DE4333920A1 (en) 1993-10-05 1995-04-13 Hoechst Ag Corticoid-17,21-dicarboxylic acid esters and corticosteroid-17-carboxylic acid ester-21-carbonic acid esters, processes for their preparation and medicaments containing them

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1044212B (en) * 1971-03-17 1980-03-20 Sigma Tau Ind Farmaceuti ESTERS OF BESAMETAZONE AND BETAMETAZONE
GB1440063A (en) * 1972-08-11 1976-06-23 Glaxo Lab Ltd 17alpha-esters of 17alpha,21-dihydroxy-20-oxo-steroids

Also Published As

Publication number Publication date
CA1058610A (en) 1979-07-17
IE42124L (en) 1976-01-31
IE42124B1 (en) 1980-06-04
BE831931A (en) 1976-01-30
ES439852A1 (en) 1977-03-01
JPS51125059A (en) 1976-11-01
FR2280383A1 (en) 1976-02-27
AU8353175A (en) 1977-02-03
DE2534051A1 (en) 1976-02-19
GB1516095A (en) 1978-06-28
FR2280383B1 (en) 1978-10-06
ZA754907B (en) 1976-07-28
DK139303B (en) 1979-01-29
DK139303C (en) 1979-08-06
SE7508654L (en) 1976-02-02
CH615442A5 (en) 1980-01-31
DK346975A (en) 1976-02-01

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