NL7116577A - - Google Patents

Info

Publication number
NL7116577A
NL7116577A NL7116577A NL7116577A NL7116577A NL 7116577 A NL7116577 A NL 7116577A NL 7116577 A NL7116577 A NL 7116577A NL 7116577 A NL7116577 A NL 7116577A NL 7116577 A NL7116577 A NL 7116577A
Authority
NL
Netherlands
Application number
NL7116577A
Other versions
NL172744B (nl
NL172744C (nl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of NL7116577A publication Critical patent/NL7116577A/xx
Publication of NL172744B publication Critical patent/NL172744B/xx
Application granted granted Critical
Publication of NL172744C publication Critical patent/NL172744C/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NL7116577A 1970-12-05 1971-12-02 Werkwijze voor het bereiden van basisch gesubstitueerde fenylacetonitrile-verbindingen en deze verbindingen bevattende geneesmiddelen met een de coronaire doorstroming bevorderende activiteit. NL172744C (nl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19702059923 DE2059923C3 (de) 1970-12-05 1970-12-05 l-a-Isopropyl-o-[(N-methyl-N-homoveratryl)v-aminopropyl] -3,4-dimethoxyphenylacetonitril, Verfahren zu dessen Herstellung und dieses enthaltende Arzneimittel

Publications (3)

Publication Number Publication Date
NL7116577A true NL7116577A (https=) 1972-06-07
NL172744B NL172744B (nl) 1983-05-16
NL172744C NL172744C (nl) 1983-10-17

Family

ID=5790091

Family Applications (1)

Application Number Title Priority Date Filing Date
NL7116577A NL172744C (nl) 1970-12-05 1971-12-02 Werkwijze voor het bereiden van basisch gesubstitueerde fenylacetonitrile-verbindingen en deze verbindingen bevattende geneesmiddelen met een de coronaire doorstroming bevorderende activiteit.

Country Status (8)

Country Link
AT (1) AT305262B (https=)
BE (1) BE776218A (https=)
CH (1) CH565748A5 (https=)
DE (1) DE2059923C3 (https=)
FR (1) FR2116564B1 (https=)
GB (1) GB1367677A (https=)
NL (1) NL172744C (https=)
YU (2) YU35346B (https=)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2946545A1 (de) 1979-11-17 1981-05-27 Basf Ag, 6700 Ludwigshafen Verfahren zur gewinnung der enantiomeren formen von 4-cyan-1-(n-methyl-n-(2'-((3'',4'',-dimethoxyphenyl))-aethyl)-amino)-5-methyl-4-(3',4',5'-trimethoxyphenyl)-hexan und dessen salzen
DE3034221A1 (de) 1980-09-11 1982-04-22 Basf Ag, 6700 Ludwigshafen Verfahren zur herstellung basisch substituierter phenylacetonitrile
DE3144150A1 (de) 1981-04-10 1982-12-09 Basf Ag, 6700 Ludwigshafen (omega)-cyan-1,(omega)-diphenyl-azaalkan-derivate, ihre herstellung und diese enthaltende arzneimittel
DE3138488A1 (de) * 1981-09-28 1983-04-14 Knoll Ag, 6700 Ludwigshafen Verwendung von basisch substituierten phenylacetonritrilen bei der vorbeugenden bekaempfung von krankheiten und mittel dafuer
DE3344755A1 (de) * 1983-12-10 1985-06-20 Basf Ag, 6700 Ludwigshafen 1,7-diphenyl-3-methylaza-7-cyan-8-methyl-nonan zur verwendung bei der bekaempfung von krankheiten
DE3635930A1 (de) * 1986-10-22 1988-04-28 Basf Ag Wirkstoffe zur anwendung bei der behandlung von tumoren
DE3603660C2 (de) * 1986-02-06 1994-09-15 Fresenius Ag Verbesserte Peritonealdialyse
DE4203547A1 (de) * 1992-02-07 1993-08-12 Knoll Ag Verfahren zur racemattrennung von verapamil
GB9319918D0 (en) * 1993-09-27 1993-11-10 Chiros Ltd Chiral compounds and their preparation
US5910601A (en) * 1994-09-26 1999-06-08 Darwin Discovery Limited Chiral nitriles, their preparation and their use for the manufacture of verapamil and analogues
US5892093A (en) * 1996-02-08 1999-04-06 Darwin Discovery Limited Resolution
AU705865B2 (en) * 1996-02-08 1999-06-03 Darwin Discovery Limited Resolution of 4-cyano-4-(3,4-dimethoxyphenyl) -5-methylhexanoic acid
WO1997044025A1 (en) * 1996-05-23 1997-11-27 G.D. Searle & Co. Pharmaceutical compositions containing non-racemic verapamil and process for optimizing the pharmaceutical activity of r- and s-verapamil
US5859279A (en) * 1996-09-10 1999-01-12 Darwin Discovery Limited Compound and process
GB9618835D0 (en) * 1996-09-10 1996-10-23 Chiroscience Ltd Process
US6667412B1 (en) 1999-03-16 2003-12-23 Eisai Co., Ltd. Nitrile compound
MXPA02000246A (es) 1999-07-06 2003-08-20 Methylgene Inc Inhibidores de °-lactamasa de sulfonamidometil fosfonato.
US6884791B2 (en) 1999-07-06 2005-04-26 Methylgene, Inc. Inhibitors of β-lactamase
JP5421908B2 (ja) * 2007-06-20 2014-02-19 マイルストーン ファーマシューティカルズ インコーポレーテッド 短時間作用型フェニルアルキルアミンカルシウムチャネルブロッカーおよびその使用
US10144703B2 (en) 2015-05-12 2018-12-04 Piramal Enterprises Limited Process for the preparation of Verapamil hydrochloride

Also Published As

Publication number Publication date
YU35348B (en) 1980-12-31
CH565748A5 (https=) 1975-08-29
NL172744B (nl) 1983-05-16
DE2059923C3 (de) 1979-01-25
FR2116564B1 (https=) 1975-03-14
GB1367677A (en) 1974-09-18
YU302371A (en) 1980-06-30
AT305262B (de) 1973-02-26
NL172744C (nl) 1983-10-17
FR2116564A1 (https=) 1972-07-13
YU35346B (en) 1980-12-31
BE776218A (fr) 1972-06-05
DE2059923B2 (de) 1978-05-18
DE2059923A1 (de) 1972-06-15
YU21879A (en) 1980-06-30

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Legal Events

Date Code Title Description
BB A search report has been drawn up
BC A request for examination has been filed
V4 Lapsed because of reaching the maxim lifetime of a patent