BE776218A - Phenyl-acetonitriles a substitution basique, optiquement actifs - Google Patents

Phenyl-acetonitriles a substitution basique, optiquement actifs

Info

Publication number
BE776218A
BE776218A BE776218A BE776218A BE776218A BE 776218 A BE776218 A BE 776218A BE 776218 A BE776218 A BE 776218A BE 776218 A BE776218 A BE 776218A BE 776218 A BE776218 A BE 776218A
Authority
BE
Belgium
Prior art keywords
acetonitrils
optically active
substitution phenyl
basic substitution
basic
Prior art date
Application number
BE776218A
Other languages
English (en)
French (fr)
Original Assignee
Knoll Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Knoll Ag filed Critical Knoll Ag
Publication of BE776218A publication Critical patent/BE776218A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
BE776218A 1970-12-05 1971-12-03 Phenyl-acetonitriles a substitution basique, optiquement actifs BE776218A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19702059923 DE2059923C3 (de) 1970-12-05 1970-12-05 l-a-Isopropyl-o-[(N-methyl-N-homoveratryl)v-aminopropyl] -3,4-dimethoxyphenylacetonitril, Verfahren zu dessen Herstellung und dieses enthaltende Arzneimittel

Publications (1)

Publication Number Publication Date
BE776218A true BE776218A (fr) 1972-06-05

Family

ID=5790091

Family Applications (1)

Application Number Title Priority Date Filing Date
BE776218A BE776218A (fr) 1970-12-05 1971-12-03 Phenyl-acetonitriles a substitution basique, optiquement actifs

Country Status (8)

Country Link
AT (1) AT305262B (xx)
BE (1) BE776218A (xx)
CH (1) CH565748A5 (xx)
DE (1) DE2059923C3 (xx)
FR (1) FR2116564B1 (xx)
GB (1) GB1367677A (xx)
NL (1) NL172744C (xx)
YU (2) YU35346B (xx)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3034221A1 (de) * 1980-09-11 1982-04-22 Basf Ag, 6700 Ludwigshafen Verfahren zur herstellung basisch substituierter phenylacetonitrile
DE3144150A1 (de) 1981-04-10 1982-12-09 Basf Ag, 6700 Ludwigshafen (omega)-cyan-1,(omega)-diphenyl-azaalkan-derivate, ihre herstellung und diese enthaltende arzneimittel
DE3138488A1 (de) * 1981-09-28 1983-04-14 Knoll Ag, 6700 Ludwigshafen Verwendung von basisch substituierten phenylacetonritrilen bei der vorbeugenden bekaempfung von krankheiten und mittel dafuer
DE3344755A1 (de) * 1983-12-10 1985-06-20 Basf Ag, 6700 Ludwigshafen 1,7-diphenyl-3-methylaza-7-cyan-8-methyl-nonan zur verwendung bei der bekaempfung von krankheiten
DE3635930A1 (de) * 1986-10-22 1988-04-28 Basf Ag Wirkstoffe zur anwendung bei der behandlung von tumoren
DE3603660C2 (de) * 1986-02-06 1994-09-15 Fresenius Ag Verbesserte Peritonealdialyse
DE4203547A1 (de) * 1992-02-07 1993-08-12 Knoll Ag Verfahren zur racemattrennung von verapamil
GB9319918D0 (en) * 1993-09-27 1993-11-10 Chiros Ltd Chiral compounds and their preparation
US5910601A (en) * 1994-09-26 1999-06-08 Darwin Discovery Limited Chiral nitriles, their preparation and their use for the manufacture of verapamil and analogues
US5892093A (en) * 1996-02-08 1999-04-06 Darwin Discovery Limited Resolution
ATE198881T1 (de) * 1996-02-08 2001-02-15 Darwin Discovery Ltd Trennung von 4-cyano-4-(3,4-dimethoxyphenyl)-5- methylexancarbonsäure
WO1997044025A1 (en) * 1996-05-23 1997-11-27 G.D. Searle & Co. Pharmaceutical compositions containing non-racemic verapamil and process for optimizing the pharmaceutical activity of r- and s-verapamil
US5859279A (en) * 1996-09-10 1999-01-12 Darwin Discovery Limited Compound and process
GB9618835D0 (en) * 1996-09-10 1996-10-23 Chiroscience Ltd Process
US6667412B1 (en) 1999-03-16 2003-12-23 Eisai Co., Ltd. Nitrile compound
US6884791B2 (en) 1999-07-06 2005-04-26 Methylgene, Inc. Inhibitors of β-lactamase
WO2001002411A1 (en) 1999-07-06 2001-01-11 Methylgene Inc. SULFONAMIDOMETHYL PHOSPHONATE INHIBITORS OF β-LACTAMASE
WO2008156820A1 (en) 2007-06-20 2008-12-24 Milestone Pharmaceuticals Inc. Short acting phenylalkylamine calcium channel blockers and uses thereof
EP3294703A4 (en) 2015-05-12 2019-01-02 Piramal Enterprises Limited A process for the preparation of verapamil hydrochloride

Also Published As

Publication number Publication date
GB1367677A (en) 1974-09-18
NL7116577A (xx) 1972-06-07
AT305262B (de) 1973-02-26
DE2059923C3 (de) 1979-01-25
DE2059923A1 (de) 1972-06-15
YU302371A (en) 1980-06-30
YU21879A (en) 1980-06-30
YU35346B (en) 1980-12-31
FR2116564A1 (xx) 1972-07-13
YU35348B (en) 1980-12-31
NL172744C (nl) 1983-10-17
CH565748A5 (xx) 1975-08-29
NL172744B (nl) 1983-05-16
FR2116564B1 (xx) 1975-03-14
DE2059923B2 (de) 1978-05-18

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Legal Events

Date Code Title Description
RE20 Patent expired

Owner name: KNOLL A.G. CHEMISCHE FABRIEKEN

Effective date: 19911203