NL7115944A - - Google Patents

Info

Publication number
NL7115944A
NL7115944A NL7115944A NL7115944A NL7115944A NL 7115944 A NL7115944 A NL 7115944A NL 7115944 A NL7115944 A NL 7115944A NL 7115944 A NL7115944 A NL 7115944A NL 7115944 A NL7115944 A NL 7115944A
Authority
NL
Netherlands
Application number
NL7115944A
Other versions
NL172324B (nl
NL172324C (nl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to BE791544D priority Critical patent/BE791544A/fr
Application filed filed Critical
Priority to NLAANVRAGE7115944,A priority patent/NL172324C/xx
Priority to GB5159172A priority patent/GB1359123A/en
Priority to CA156,314A priority patent/CA1003408A/en
Priority to FR7240482A priority patent/FR2160471B1/fr
Priority to DE2256055A priority patent/DE2256055C2/de
Priority to US306524A priority patent/US3879372A/en
Priority to CH1667772A priority patent/CH584188A5/xx
Priority to IT54090/72A priority patent/IT982394B/it
Priority to DK575372A priority patent/DK149126C/da
Priority to JP11546672A priority patent/JPS5417727B2/ja
Priority to SE7215076A priority patent/SE393603B/xx
Publication of NL7115944A publication Critical patent/NL7115944A/xx
Publication of NL172324B publication Critical patent/NL172324B/xx
Application granted granted Critical
Publication of NL172324C publication Critical patent/NL172324C/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/66Nitrogen atoms
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L27/00Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/30Artificial sweetening agents
    • A23L27/31Artificial sweetening agents containing amino acids, nucleotides, peptides or derivatives
    • A23L27/32Artificial sweetening agents containing amino acids, nucleotides, peptides or derivatives containing dipeptides or derivatives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06104Dipeptides with the first amino acid being acidic
    • C07K5/06113Asp- or Asn-amino acid
    • C07K5/06121Asp- or Asn-amino acid the second amino acid being aromatic or cycloaliphatic
    • C07K5/0613Aspartame
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/801Peptide sweetners

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Nutrition Science (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NLAANVRAGE7115944,A 1971-11-19 1971-11-19 Werkwijze voor het bereiden van asparagyl-aminozuur-alkylesters met 1-6 koolstofatomen in de alkylgroep door reactie van een n-beschermd asparaginezuuranhydride met een zout van een alkylester van een aminozuur. NL172324C (nl)

Priority Applications (12)

Application Number Priority Date Filing Date Title
BE791544D BE791544A (fr) 1971-11-19 Preparation d'esters alkyliques de dipeptide
NLAANVRAGE7115944,A NL172324C (nl) 1971-11-19 1971-11-19 Werkwijze voor het bereiden van asparagyl-aminozuur-alkylesters met 1-6 koolstofatomen in de alkylgroep door reactie van een n-beschermd asparaginezuuranhydride met een zout van een alkylester van een aminozuur.
GB5159172A GB1359123A (en) 1971-11-19 1972-11-08 Preparation of aspartyl amino-acid alkyl esters
CA156,314A CA1003408A (en) 1971-11-19 1972-11-14 Preparation of dipeptide-alkylesters
DE2256055A DE2256055C2 (de) 1971-11-19 1972-11-15 Verfahren zur Herstellung von N-terminal den α-L-Asparagylrest enthaltenden, als Süßstoff verwendbaren Dipeptid-nieder-alkylestern
US306524A US3879372A (en) 1971-11-19 1972-11-15 Preparation of aspartyl dipeptide-alkylesters using aqueous solvent
FR7240482A FR2160471B1 (fr) 1971-11-19 1972-11-15
CH1667772A CH584188A5 (fr) 1971-11-19 1972-11-16
IT54090/72A IT982394B (it) 1971-11-19 1972-11-16 Procedimento per la produzione di esteri alchilici di asparagil ammincacidi e prodotto belativo
DK575372A DK149126C (da) 1971-11-19 1972-11-17 Fremgangsmaade til fremstilling af c1-4-alkylestere af l-aspartyl-l-aminosyrer
JP11546672A JPS5417727B2 (fr) 1971-11-19 1972-11-17
SE7215076A SE393603B (sv) 1971-11-19 1972-11-20 Sett att framstella lagalkylestrar av aspartylaminosyra

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NLAANVRAGE7115944,A NL172324C (nl) 1971-11-19 1971-11-19 Werkwijze voor het bereiden van asparagyl-aminozuur-alkylesters met 1-6 koolstofatomen in de alkylgroep door reactie van een n-beschermd asparaginezuuranhydride met een zout van een alkylester van een aminozuur.

Publications (3)

Publication Number Publication Date
NL7115944A true NL7115944A (fr) 1973-05-22
NL172324B NL172324B (nl) 1983-03-16
NL172324C NL172324C (nl) 1983-08-16

Family

ID=19814512

Family Applications (1)

Application Number Title Priority Date Filing Date
NLAANVRAGE7115944,A NL172324C (nl) 1971-11-19 1971-11-19 Werkwijze voor het bereiden van asparagyl-aminozuur-alkylesters met 1-6 koolstofatomen in de alkylgroep door reactie van een n-beschermd asparaginezuuranhydride met een zout van een alkylester van een aminozuur.

Country Status (12)

Country Link
US (1) US3879372A (fr)
JP (1) JPS5417727B2 (fr)
BE (1) BE791544A (fr)
CA (1) CA1003408A (fr)
CH (1) CH584188A5 (fr)
DE (1) DE2256055C2 (fr)
DK (1) DK149126C (fr)
FR (1) FR2160471B1 (fr)
GB (1) GB1359123A (fr)
IT (1) IT982394B (fr)
NL (1) NL172324C (fr)
SE (1) SE393603B (fr)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0035047B1 (fr) * 1980-03-03 1984-01-25 Ajinomoto Co., Inc. Procédé pour la préparation d'un ester alkylique inférieur de l'alpha-L-aspartyl-L-phénylalanine et intermédiaire pour cette préparation
US4333872A (en) * 1980-05-27 1982-06-08 Chimicasa Gmbh Method of producing α-L-aspartyl-L-phenylalanine methylester
NL8005006A (nl) * 1980-09-04 1982-04-01 Stamicarbon Dipeptide-zoetstof.
JPS57131746A (en) * 1981-02-10 1982-08-14 Ajinomoto Co Inc Removal of n-formyl group
IE810577L (en) * 1983-05-31 1982-09-16 Prendergast Angela Apparatus for fermentation
FR2516077A1 (fr) * 1981-11-06 1983-05-13 Human Pharm Sa Laboratoires Procede de preparation de l'ester-methylique de l'a-aspartyl phenylalanine
JPS58185545A (ja) * 1982-04-22 1983-10-29 Ajinomoto Co Inc α−L−アスパルチル−L−フエニルアラニンメチルエステルまたはその塩酸塩の製法
IT1152488B (it) * 1982-08-06 1986-12-31 Pierrel Spa Procedimento per la preparazione dell'anidride dell'acido n-formil-l-aspartico
IT1155060B (it) * 1982-09-02 1987-01-21 Sirac Srl Procedimento per la preparazione di esteri alchilici della alfa-l-aspartil-l-fenilalanina
US4555362A (en) * 1983-06-20 1985-11-26 G. D. Searle & Co. Method and intermediates for producing α-L-aspartyl-L-phenylalanine
GB8321802D0 (en) * 1983-08-12 1983-09-14 Erba Farmitalia Aspartame synthesis
JPS6075497A (ja) * 1983-09-30 1985-04-27 Ajinomoto Co Inc Ν−保護−α−L−アスパルチル−L−フェニルアラニンメチルエステルの製造法
JPS60164495A (ja) * 1984-01-16 1985-08-27 モンサント コンパニー N‐ホルミルアミノ酸とペプチド残基の酵素的結合法
FR2558471B1 (fr) * 1984-01-19 1987-11-20 Isochem Sa Procede de preparation d'aspartyl peptides, et nouveaux intermediaires de synthese
JPH07636B2 (ja) * 1984-12-17 1995-01-11 三井東圧化学株式会社 N−ホルミル−α−アスパルチルフエニルアラニンの製造法
JPS61148198A (ja) * 1984-12-22 1986-07-05 Ajinomoto Co Inc 新規トリペプチド化合物および甘味剤
CA1277098C (fr) * 1984-12-27 1990-11-27 Mitsui Toatsu Chemicals, Inc. Procede pour la preparation de l'ester methylique de l' -l-aspartyl-l-phenylalanine
JPH0680074B2 (ja) * 1985-07-01 1994-10-12 味の素株式会社 N―ホルミル―L―α―アスパルチル―L―フェニルアラニンの製法
AU561384B2 (en) * 1985-03-26 1987-05-07 Mitsui Toatsu Chemicals Inc. Preparation of -l-aspartyl-l-phenylalanine methyl ester or hydrochloride thereof
US4677220A (en) * 1985-10-31 1987-06-30 Monsanto Company Process for the preparation of α-L-aspartyl-L-phenylalanine methyl ester
US4730076A (en) * 1985-12-18 1988-03-08 Nippon Kayaku Kabushiki Kaisha Process for producing α-aspartyl-phenylalanine ester
EP0270345B1 (fr) * 1986-12-05 1992-07-22 MITSUI TOATSU CHEMICALS, Inc. Préparation d'alpha-L-aspartyl-L-phényl-alanine méthyl ester ou de son hydrohalide
JPH0832719B2 (ja) * 1986-12-19 1996-03-29 三井東圧化学株式会社 吸湿性の小さいα−L−アスパルチル−L−フエニルアラニンメチルエステルの製造法
US4774027A (en) * 1987-11-13 1988-09-27 General Foods Corporation Process for the preparation of N-L-aminodicarboxylic acid esters and new compositions used in the preparation thereof
US5017690A (en) * 1989-08-11 1991-05-21 W. R. Grace & Co.-Conn. Deblocking N-formyl aspartame compounds
DE69211756T3 (de) * 1991-04-24 2001-04-19 Mitsui Chemicals Inc Verfahren zur Herstellung von alpha-L-aspartyl-L-phenylalaninmethylester
US5616775A (en) * 1994-05-05 1997-04-01 Bristol-Myers Squibb Co. Process for preparing homocystein analogs useful as intermediates for compounds containing a fused bicyclic ring

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3786039A (en) * 1969-04-30 1974-01-15 Ajinomoto Kk Method of producing alpha-l-aspartyl-l-phenylalanine lower alkyl esters
GB1309605A (en) * 1970-01-31 1973-03-14 Ajinomoto Kk Process for producing alpha-dipeptide esters of l-aspartic acid
JPS524972B2 (fr) * 1972-05-22 1977-02-08
US3769333A (en) * 1972-08-07 1973-10-30 American Home Prod L-aspartic acid derivatives

Also Published As

Publication number Publication date
FR2160471A1 (fr) 1973-06-29
CA1003408A (en) 1977-01-11
DK149126B (da) 1986-02-03
SE393603B (sv) 1977-05-16
US3879372A (en) 1975-04-22
IT982394B (it) 1974-10-21
JPS5417727B2 (fr) 1979-07-02
DE2256055C2 (de) 1984-07-05
BE791544A (fr) 1973-05-17
GB1359123A (en) 1974-07-10
DE2256055A1 (de) 1973-05-24
NL172324B (nl) 1983-03-16
DK149126C (da) 1986-06-23
FR2160471B1 (fr) 1975-01-03
NL172324C (nl) 1983-08-16
CH584188A5 (fr) 1977-01-31
JPS4861451A (fr) 1973-08-28

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Legal Events

Date Code Title Description
V1 Lapsed because of non-payment of the annual fee