NL7106122A - - Google Patents

Info

Publication number
NL7106122A
NL7106122A NL7106122A NL7106122A NL7106122A NL 7106122 A NL7106122 A NL 7106122A NL 7106122 A NL7106122 A NL 7106122A NL 7106122 A NL7106122 A NL 7106122A NL 7106122 A NL7106122 A NL 7106122A
Authority
NL
Netherlands
Application number
NL7106122A
Other versions
NL174143C (nl
NL174143B (nl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of NL7106122A publication Critical patent/NL7106122A/xx
Publication of NL174143B publication Critical patent/NL174143B/xx
Application granted granted Critical
Publication of NL174143C publication Critical patent/NL174143C/xx

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/10Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
    • C07D295/104Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/108Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00Ethers; Compounds having groups, groups or groups
    • C07C43/02Ethers
    • C07C43/20Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/205Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring the aromatic ring being a non-condensed ring
    • C07C43/2055Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring the aromatic ring being a non-condensed ring containing more than one ether bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/42Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by hydrolysis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/125Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/13Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NLAANVRAGE7106122,A 1970-05-06 1971-05-05 Werkwijze ter bereiding van floroglucinolverbindingen met vasodilatatieve werking, alsmede werkwijze ter bereiding van farmaceutische preparaten met een dergelijke werking. NL174143C (nl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB2186570 1970-05-06

Publications (3)

Publication Number Publication Date
NL7106122A true NL7106122A (es) 1971-11-09
NL174143B NL174143B (nl) 1983-12-01
NL174143C NL174143C (nl) 1984-05-01

Family

ID=10170122

Family Applications (1)

Application Number Title Priority Date Filing Date
NLAANVRAGE7106122,A NL174143C (nl) 1970-05-06 1971-05-05 Werkwijze ter bereiding van floroglucinolverbindingen met vasodilatatieve werking, alsmede werkwijze ter bereiding van farmaceutische preparaten met een dergelijke werking.

Country Status (12)

Country Link
US (1) US3895030A (es)
JP (1) JPS5123492B1 (es)
AU (1) AU2849871A (es)
BE (1) BE766390A (es)
CA (1) CA935431A (es)
CH (1) CH530369A (es)
DE (1) DE2122144A1 (es)
ES (1) ES390905A1 (es)
FR (1) FR2092133B1 (es)
GB (1) GB1325192A (es)
LU (1) LU63096A1 (es)
NL (1) NL174143C (es)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2841702C2 (de) * 1977-09-26 1994-08-04 Lafon Labor Verwendung von (2,4,6-Trihydroxyphenyl)-(3-pyrrolidinopropyl)keton zur Hemmung der Blutplättchenaggregation und zur Behandlung des Wundliegens
FR2404003A1 (fr) * 1977-09-26 1979-04-20 Lafon Labor Nouveaux derives de phloroglucinol, leur procede de preparation et leur application en therapeutique
JPS56104835A (en) * 1980-01-23 1981-08-20 Shionogi & Co Ltd Novel synthesis of 2-haloacetylphenols
FR2503143A1 (fr) * 1981-03-31 1982-10-08 Lafon Labor Nouveaux derives de phenacylamine, leur utilisation en therapeutique et leur procede de preparation
FR2504136A1 (fr) * 1981-04-15 1982-10-22 Lafon Labor (2,6-dimethoxy-4-hydroxyphenyl)-(3-piperidinopropyl)-cetone et ses sels d'addition, utilisation en therapeutique et procede de preparation
FR2534912B1 (fr) * 1982-10-26 1985-06-28 Lafon Labor Nouveaux derives de (2,4,6-trimethoxyphenyl) - (3-piperidinopropyl) -cetone, utilisation en therapeutique et procede de preparation
FR2534916B1 (fr) * 1982-10-26 1985-11-22 Lafon Labor Nouveaux derives de phenyl-(3-aminopropyl)-cetone, utilisation en therapeutique et procede de preparation
FR2555576B1 (fr) * 1983-11-25 1986-06-13 Lafon Labor Derives de n-(methoxyphenacyl)-amine, utilisation notamment en therapeutique et procede de preparation
DE3520910A1 (de) * 1985-06-11 1986-12-11 Avesta Nyby Powder AB, Torshälla Verfahren zur herstellung von strangpressbolzen, zur pulvermetallurgischen erzeugung von rohren
FR2584715B1 (fr) * 1985-07-10 1987-10-09 Lafon Labor Phenyl-(3-hexamethyleneiminopropyl)-cetone, procede de preparation et utilisation en therapeutique
FR2597864B1 (fr) * 1986-04-28 1990-11-16 Lafon Labor Nouveaux derives de la n-((trimethoxy-2,4,6-benzoyl)-3 propyl) piperidine, leurs procedes de preparation et leur application en therapeutique
US4870083A (en) * 1987-11-24 1989-09-26 Merrell Dow Pharmaceuticals Inc. 1,4-Disubstituted-piperidinyl compounds useful as analgesics and muscle relaxants
IT1231260B (it) * 1988-11-16 1991-11-28 Sergio Bertini Curri Farmaco e metodo per aumentare volume e velocita' del flusso microcircolatorio capillare a livello cutaneo
CN1681495B (zh) 2002-08-19 2010-05-12 辉瑞产品公司 用于治疗过度增生性疾病的组合物
US20050037063A1 (en) * 2003-07-21 2005-02-17 Bolton Anthony E. Combined therapies
GB0410215D0 (en) * 2004-05-07 2004-06-09 Lescroart Pol Nerve damage
GB2414665A (en) * 2004-06-01 2005-12-07 Pol Lescroart Aminoketone derivatives of phloroglucinol for the treatment of motor neuron disease
US20060063803A1 (en) * 2004-09-23 2006-03-23 Pfizer Inc 4-Amino substituted-2-substituted-1,2,3,4-tetrahydroquinoline compounds
US7741317B2 (en) 2005-10-21 2010-06-22 Bristol-Myers Squibb Company LXR modulators
US7888376B2 (en) 2005-11-23 2011-02-15 Bristol-Myers Squibb Company Heterocyclic CETP inhibitors
US7919506B2 (en) 2006-03-10 2011-04-05 Pfizer Inc. Dibenzyl amine compounds and derivatives
US8383660B2 (en) 2006-03-10 2013-02-26 Pfizer Inc. Dibenzyl amine compounds and derivatives
EP2027087A2 (en) 2006-05-18 2009-02-25 MannKind Corporation Intracellular kinase inhibitors
ES2382009T3 (es) 2006-12-01 2012-06-04 Bristol-Myers Squibb Company Derivados de N-((3-bencil)-2,2-(bis-fenil-)-propan-1-amina como inhibidores de CETP para el tratamiento de aterosclerosis y enfermedades cardiovasculares
CN103450077B (zh) * 2007-06-08 2016-07-06 满康德股份有限公司 IRE-1α抑制剂
CN101220006B (zh) * 2007-12-19 2010-09-01 齐鲁天和惠世制药有限公司 丁咯地尔的制备方法
CN102898404A (zh) * 2012-10-11 2013-01-30 南通康鑫药业有限公司 一种盐酸丁咯地尔的制备方法
JP2016516804A (ja) 2013-04-17 2016-06-09 ファイザー・インク 心血管疾患を治療するためのn−ピペリジン−3−イルベンズアミド誘導体
WO2016055901A1 (en) 2014-10-08 2016-04-14 Pfizer Inc. Substituted amide compounds
CN105924411B (zh) * 2016-05-10 2018-12-11 王珍 一种盐酸丁咯地尔化合物及其药物组合物
EP3911648A4 (en) 2019-01-18 2022-10-26 Astrazeneca AB PCSK9 INHIBITORS AND METHODS OF USE THEREOF

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1115992A (en) * 1965-03-26 1968-06-06 Lafon Labor Improvements in or relating to n-piperidino-alkoxyacetophenones

Also Published As

Publication number Publication date
GB1325192A (en) 1973-08-01
US3895030A (en) 1975-07-15
FR2092133A1 (es) 1972-01-21
AU2849871A (en) 1972-11-09
NL174143C (nl) 1984-05-01
LU63096A1 (es) 1971-08-31
BE766390A (fr) 1971-09-16
DE2122144A1 (de) 1971-11-25
FR2092133B1 (es) 1974-03-22
ES390905A1 (es) 1973-06-01
CA935431A (en) 1973-10-16
NL174143B (nl) 1983-12-01
CH530369A (fr) 1972-11-15
JPS5123492B1 (es) 1976-07-17

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Legal Events

Date Code Title Description
V4 Discontinued because of reaching the maximum lifetime of a patent