JPS5123492B1 - - Google Patents
Info
- Publication number
- JPS5123492B1 JPS5123492B1 JP46029486A JP2948671A JPS5123492B1 JP S5123492 B1 JPS5123492 B1 JP S5123492B1 JP 46029486 A JP46029486 A JP 46029486A JP 2948671 A JP2948671 A JP 2948671A JP S5123492 B1 JPS5123492 B1 JP S5123492B1
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
- C07D295/104—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/108—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
- C07C43/205—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring the aromatic ring being a non-condensed ring
- C07C43/2055—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring the aromatic ring being a non-condensed ring containing more than one ether bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/42—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by hydrolysis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB2186570 | 1970-05-06 |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS5123492B1 true JPS5123492B1 (ja) | 1976-07-17 |
Family
ID=10170122
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP46029486A Pending JPS5123492B1 (ja) | 1970-05-06 | 1971-05-06 |
Country Status (12)
Country | Link |
---|---|
US (1) | US3895030A (ja) |
JP (1) | JPS5123492B1 (ja) |
AU (1) | AU2849871A (ja) |
BE (1) | BE766390A (ja) |
CA (1) | CA935431A (ja) |
CH (1) | CH530369A (ja) |
DE (1) | DE2122144A1 (ja) |
ES (1) | ES390905A1 (ja) |
FR (1) | FR2092133B1 (ja) |
GB (1) | GB1325192A (ja) |
LU (1) | LU63096A1 (ja) |
NL (1) | NL174143C (ja) |
Families Citing this family (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2404003A1 (fr) * | 1977-09-26 | 1979-04-20 | Lafon Labor | Nouveaux derives de phloroglucinol, leur procede de preparation et leur application en therapeutique |
DE2841702C2 (de) * | 1977-09-26 | 1994-08-04 | Lafon Labor | Verwendung von (2,4,6-Trihydroxyphenyl)-(3-pyrrolidinopropyl)keton zur Hemmung der Blutplättchenaggregation und zur Behandlung des Wundliegens |
JPS56104835A (en) * | 1980-01-23 | 1981-08-20 | Shionogi & Co Ltd | Novel synthesis of 2-haloacetylphenols |
FR2503143A1 (fr) * | 1981-03-31 | 1982-10-08 | Lafon Labor | Nouveaux derives de phenacylamine, leur utilisation en therapeutique et leur procede de preparation |
FR2504136A1 (fr) * | 1981-04-15 | 1982-10-22 | Lafon Labor | (2,6-dimethoxy-4-hydroxyphenyl)-(3-piperidinopropyl)-cetone et ses sels d'addition, utilisation en therapeutique et procede de preparation |
FR2534916B1 (fr) * | 1982-10-26 | 1985-11-22 | Lafon Labor | Nouveaux derives de phenyl-(3-aminopropyl)-cetone, utilisation en therapeutique et procede de preparation |
FR2534912B1 (fr) * | 1982-10-26 | 1985-06-28 | Lafon Labor | Nouveaux derives de (2,4,6-trimethoxyphenyl) - (3-piperidinopropyl) -cetone, utilisation en therapeutique et procede de preparation |
FR2555576B1 (fr) * | 1983-11-25 | 1986-06-13 | Lafon Labor | Derives de n-(methoxyphenacyl)-amine, utilisation notamment en therapeutique et procede de preparation |
DE3520910A1 (de) * | 1985-06-11 | 1986-12-11 | Avesta Nyby Powder AB, Torshälla | Verfahren zur herstellung von strangpressbolzen, zur pulvermetallurgischen erzeugung von rohren |
FR2584715B1 (fr) * | 1985-07-10 | 1987-10-09 | Lafon Labor | Phenyl-(3-hexamethyleneiminopropyl)-cetone, procede de preparation et utilisation en therapeutique |
FR2597864B1 (fr) * | 1986-04-28 | 1990-11-16 | Lafon Labor | Nouveaux derives de la n-((trimethoxy-2,4,6-benzoyl)-3 propyl) piperidine, leurs procedes de preparation et leur application en therapeutique |
US4870083A (en) * | 1987-11-24 | 1989-09-26 | Merrell Dow Pharmaceuticals Inc. | 1,4-Disubstituted-piperidinyl compounds useful as analgesics and muscle relaxants |
IT1231260B (it) * | 1988-11-16 | 1991-11-28 | Sergio Bertini Curri | Farmaco e metodo per aumentare volume e velocita' del flusso microcircolatorio capillare a livello cutaneo |
OA12905A (en) | 2002-08-19 | 2006-10-13 | Pfizer Prod Inc | Combination therapy for hyperproliferative diseases. |
US20050037063A1 (en) * | 2003-07-21 | 2005-02-17 | Bolton Anthony E. | Combined therapies |
GB0410215D0 (en) * | 2004-05-07 | 2004-06-09 | Lescroart Pol | Nerve damage |
GB2414665A (en) * | 2004-06-01 | 2005-12-07 | Pol Lescroart | Aminoketone derivatives of phloroglucinol for the treatment of motor neuron disease |
US20060063803A1 (en) * | 2004-09-23 | 2006-03-23 | Pfizer Inc | 4-Amino substituted-2-substituted-1,2,3,4-tetrahydroquinoline compounds |
US7741317B2 (en) | 2005-10-21 | 2010-06-22 | Bristol-Myers Squibb Company | LXR modulators |
US7888376B2 (en) | 2005-11-23 | 2011-02-15 | Bristol-Myers Squibb Company | Heterocyclic CETP inhibitors |
US7919506B2 (en) | 2006-03-10 | 2011-04-05 | Pfizer Inc. | Dibenzyl amine compounds and derivatives |
US8383660B2 (en) | 2006-03-10 | 2013-02-26 | Pfizer Inc. | Dibenzyl amine compounds and derivatives |
MX2008014450A (es) | 2006-05-18 | 2009-03-09 | Mannkind Corp | Inhibidores de cinasa intracelular. |
ES2382009T3 (es) | 2006-12-01 | 2012-06-04 | Bristol-Myers Squibb Company | Derivados de N-((3-bencil)-2,2-(bis-fenil-)-propan-1-amina como inhibidores de CETP para el tratamiento de aterosclerosis y enfermedades cardiovasculares |
ES2569660T3 (es) | 2007-06-08 | 2016-05-12 | Mannkind Corporation | Inhibidores de la IRE-1alfa |
CN101220006B (zh) * | 2007-12-19 | 2010-09-01 | 齐鲁天和惠世制药有限公司 | 丁咯地尔的制备方法 |
CN102898404A (zh) * | 2012-10-11 | 2013-01-30 | 南通康鑫药业有限公司 | 一种盐酸丁咯地尔的制备方法 |
RU2618628C1 (ru) | 2013-04-17 | 2017-05-05 | Пфайзер Инк. | Производные N-пиперидин-3-илбензамида для лечения сердечно-сосудистых заболеваний |
WO2016055901A1 (en) | 2014-10-08 | 2016-04-14 | Pfizer Inc. | Substituted amide compounds |
CN105924411B (zh) * | 2016-05-10 | 2018-12-11 | 王珍 | 一种盐酸丁咯地尔化合物及其药物组合物 |
EA202191892A1 (ru) | 2019-01-18 | 2022-02-24 | Астразенека Аб | Ингибиторы pcsk9 и способы их применения |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1115992A (en) * | 1965-03-26 | 1968-06-06 | Lafon Labor | Improvements in or relating to n-piperidino-alkoxyacetophenones |
-
1971
- 1971-04-20 FR FR7114011A patent/FR2092133B1/fr not_active Expired
- 1971-04-27 CH CH619171A patent/CH530369A/fr not_active IP Right Cessation
- 1971-04-28 BE BE766390A patent/BE766390A/xx not_active IP Right Cessation
- 1971-05-03 US US139894A patent/US3895030A/en not_active Expired - Lifetime
- 1971-05-04 LU LU63096D patent/LU63096A1/xx unknown
- 1971-05-04 AU AU28498/71A patent/AU2849871A/en not_active Expired
- 1971-05-05 ES ES390905A patent/ES390905A1/es not_active Expired
- 1971-05-05 DE DE19712122144 patent/DE2122144A1/de active Pending
- 1971-05-05 CA CA112197A patent/CA935431A/en not_active Expired
- 1971-05-05 NL NLAANVRAGE7106122,A patent/NL174143C/xx not_active IP Right Cessation
- 1971-05-06 JP JP46029486A patent/JPS5123492B1/ja active Pending
- 1971-05-06 GB GB2186570A patent/GB1325192A/en not_active Expired
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1115992A (en) * | 1965-03-26 | 1968-06-06 | Lafon Labor | Improvements in or relating to n-piperidino-alkoxyacetophenones |
Also Published As
Publication number | Publication date |
---|---|
CH530369A (fr) | 1972-11-15 |
US3895030A (en) | 1975-07-15 |
NL174143B (nl) | 1983-12-01 |
NL174143C (nl) | 1984-05-01 |
CA935431A (en) | 1973-10-16 |
AU2849871A (en) | 1972-11-09 |
LU63096A1 (ja) | 1971-08-31 |
NL7106122A (ja) | 1971-11-09 |
FR2092133B1 (ja) | 1974-03-22 |
BE766390A (fr) | 1971-09-16 |
FR2092133A1 (ja) | 1972-01-21 |
ES390905A1 (es) | 1973-06-01 |
DE2122144A1 (de) | 1971-11-25 |
GB1325192A (en) | 1973-08-01 |