CH530369A - Procédé de préparation d'un composé aminocétonique du phloroglucinol - Google Patents
Procédé de préparation d'un composé aminocétonique du phloroglucinolInfo
- Publication number
- CH530369A CH530369A CH619171A CH619171A CH530369A CH 530369 A CH530369 A CH 530369A CH 619171 A CH619171 A CH 619171A CH 619171 A CH619171 A CH 619171A CH 530369 A CH530369 A CH 530369A
- Authority
- CH
- Switzerland
- Prior art keywords
- phloroglucinol
- preparing
- aminoketone compound
- aminoketone
- compound
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
- C07D295/104—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/108—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
- C07C43/205—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring the aromatic ring being a non-condensed ring
- C07C43/2055—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring the aromatic ring being a non-condensed ring containing more than one ether bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/42—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by hydrolysis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB2186570 | 1970-05-06 |
Publications (1)
Publication Number | Publication Date |
---|---|
CH530369A true CH530369A (fr) | 1972-11-15 |
Family
ID=10170122
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CH619171A CH530369A (fr) | 1970-05-06 | 1971-04-27 | Procédé de préparation d'un composé aminocétonique du phloroglucinol |
Country Status (12)
Country | Link |
---|---|
US (1) | US3895030A (fr) |
JP (1) | JPS5123492B1 (fr) |
AU (1) | AU2849871A (fr) |
BE (1) | BE766390A (fr) |
CA (1) | CA935431A (fr) |
CH (1) | CH530369A (fr) |
DE (1) | DE2122144A1 (fr) |
ES (1) | ES390905A1 (fr) |
FR (1) | FR2092133B1 (fr) |
GB (1) | GB1325192A (fr) |
LU (1) | LU63096A1 (fr) |
NL (1) | NL174143C (fr) |
Families Citing this family (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2841702C2 (de) * | 1977-09-26 | 1994-08-04 | Lafon Labor | Verwendung von (2,4,6-Trihydroxyphenyl)-(3-pyrrolidinopropyl)keton zur Hemmung der Blutplättchenaggregation und zur Behandlung des Wundliegens |
FR2404003A1 (fr) * | 1977-09-26 | 1979-04-20 | Lafon Labor | Nouveaux derives de phloroglucinol, leur procede de preparation et leur application en therapeutique |
JPS56104835A (en) * | 1980-01-23 | 1981-08-20 | Shionogi & Co Ltd | Novel synthesis of 2-haloacetylphenols |
FR2503143A1 (fr) * | 1981-03-31 | 1982-10-08 | Lafon Labor | Nouveaux derives de phenacylamine, leur utilisation en therapeutique et leur procede de preparation |
FR2504136A1 (fr) * | 1981-04-15 | 1982-10-22 | Lafon Labor | (2,6-dimethoxy-4-hydroxyphenyl)-(3-piperidinopropyl)-cetone et ses sels d'addition, utilisation en therapeutique et procede de preparation |
FR2534912B1 (fr) * | 1982-10-26 | 1985-06-28 | Lafon Labor | Nouveaux derives de (2,4,6-trimethoxyphenyl) - (3-piperidinopropyl) -cetone, utilisation en therapeutique et procede de preparation |
FR2534916B1 (fr) * | 1982-10-26 | 1985-11-22 | Lafon Labor | Nouveaux derives de phenyl-(3-aminopropyl)-cetone, utilisation en therapeutique et procede de preparation |
FR2555576B1 (fr) * | 1983-11-25 | 1986-06-13 | Lafon Labor | Derives de n-(methoxyphenacyl)-amine, utilisation notamment en therapeutique et procede de preparation |
DE3520910A1 (de) * | 1985-06-11 | 1986-12-11 | Avesta Nyby Powder AB, Torshälla | Verfahren zur herstellung von strangpressbolzen, zur pulvermetallurgischen erzeugung von rohren |
FR2584715B1 (fr) * | 1985-07-10 | 1987-10-09 | Lafon Labor | Phenyl-(3-hexamethyleneiminopropyl)-cetone, procede de preparation et utilisation en therapeutique |
FR2597864B1 (fr) * | 1986-04-28 | 1990-11-16 | Lafon Labor | Nouveaux derives de la n-((trimethoxy-2,4,6-benzoyl)-3 propyl) piperidine, leurs procedes de preparation et leur application en therapeutique |
US4870083A (en) * | 1987-11-24 | 1989-09-26 | Merrell Dow Pharmaceuticals Inc. | 1,4-Disubstituted-piperidinyl compounds useful as analgesics and muscle relaxants |
IT1231260B (it) * | 1988-11-16 | 1991-11-28 | Sergio Bertini Curri | Farmaco e metodo per aumentare volume e velocita' del flusso microcircolatorio capillare a livello cutaneo |
CN1681495B (zh) | 2002-08-19 | 2010-05-12 | 辉瑞产品公司 | 用于治疗过度增生性疾病的组合物 |
US20050037063A1 (en) * | 2003-07-21 | 2005-02-17 | Bolton Anthony E. | Combined therapies |
GB0410215D0 (en) * | 2004-05-07 | 2004-06-09 | Lescroart Pol | Nerve damage |
GB2414665A (en) * | 2004-06-01 | 2005-12-07 | Pol Lescroart | Aminoketone derivatives of phloroglucinol for the treatment of motor neuron disease |
US20060063803A1 (en) * | 2004-09-23 | 2006-03-23 | Pfizer Inc | 4-Amino substituted-2-substituted-1,2,3,4-tetrahydroquinoline compounds |
US7741317B2 (en) | 2005-10-21 | 2010-06-22 | Bristol-Myers Squibb Company | LXR modulators |
US7888376B2 (en) | 2005-11-23 | 2011-02-15 | Bristol-Myers Squibb Company | Heterocyclic CETP inhibitors |
US7919506B2 (en) | 2006-03-10 | 2011-04-05 | Pfizer Inc. | Dibenzyl amine compounds and derivatives |
US8383660B2 (en) | 2006-03-10 | 2013-02-26 | Pfizer Inc. | Dibenzyl amine compounds and derivatives |
EP2027087A2 (fr) | 2006-05-18 | 2009-02-25 | MannKind Corporation | Inhibiteurs de kinases intracellulaires |
ES2382009T3 (es) | 2006-12-01 | 2012-06-04 | Bristol-Myers Squibb Company | Derivados de N-((3-bencil)-2,2-(bis-fenil-)-propan-1-amina como inhibidores de CETP para el tratamiento de aterosclerosis y enfermedades cardiovasculares |
CN103450077B (zh) * | 2007-06-08 | 2016-07-06 | 满康德股份有限公司 | IRE-1α抑制剂 |
CN101220006B (zh) * | 2007-12-19 | 2010-09-01 | 齐鲁天和惠世制药有限公司 | 丁咯地尔的制备方法 |
CN102898404A (zh) * | 2012-10-11 | 2013-01-30 | 南通康鑫药业有限公司 | 一种盐酸丁咯地尔的制备方法 |
JP2016516804A (ja) | 2013-04-17 | 2016-06-09 | ファイザー・インク | 心血管疾患を治療するためのn−ピペリジン−3−イルベンズアミド誘導体 |
WO2016055901A1 (fr) | 2014-10-08 | 2016-04-14 | Pfizer Inc. | Composés d'amide substitué |
CN105924411B (zh) * | 2016-05-10 | 2018-12-11 | 王珍 | 一种盐酸丁咯地尔化合物及其药物组合物 |
EP3911648A4 (fr) | 2019-01-18 | 2022-10-26 | Astrazeneca AB | Inhibiteurs de pcsk9 et leurs procédés d'utilisation |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1115992A (en) * | 1965-03-26 | 1968-06-06 | Lafon Labor | Improvements in or relating to n-piperidino-alkoxyacetophenones |
-
1971
- 1971-04-20 FR FR7114011A patent/FR2092133B1/fr not_active Expired
- 1971-04-27 CH CH619171A patent/CH530369A/fr not_active IP Right Cessation
- 1971-04-28 BE BE766390A patent/BE766390A/fr not_active IP Right Cessation
- 1971-05-03 US US139894A patent/US3895030A/en not_active Expired - Lifetime
- 1971-05-04 AU AU28498/71A patent/AU2849871A/en not_active Expired
- 1971-05-04 LU LU63096D patent/LU63096A1/xx unknown
- 1971-05-05 ES ES390905A patent/ES390905A1/es not_active Expired
- 1971-05-05 DE DE19712122144 patent/DE2122144A1/de active Pending
- 1971-05-05 NL NLAANVRAGE7106122,A patent/NL174143C/xx not_active IP Right Cessation
- 1971-05-05 CA CA112197A patent/CA935431A/en not_active Expired
- 1971-05-06 GB GB2186570A patent/GB1325192A/en not_active Expired
- 1971-05-06 JP JP46029486A patent/JPS5123492B1/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
GB1325192A (en) | 1973-08-01 |
US3895030A (en) | 1975-07-15 |
FR2092133A1 (fr) | 1972-01-21 |
AU2849871A (en) | 1972-11-09 |
NL174143C (nl) | 1984-05-01 |
LU63096A1 (fr) | 1971-08-31 |
BE766390A (fr) | 1971-09-16 |
DE2122144A1 (de) | 1971-11-25 |
FR2092133B1 (fr) | 1974-03-22 |
NL7106122A (fr) | 1971-11-09 |
ES390905A1 (es) | 1973-06-01 |
CA935431A (en) | 1973-10-16 |
NL174143B (nl) | 1983-12-01 |
JPS5123492B1 (fr) | 1976-07-17 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PL | Patent ceased |