NL6910859A - - Google Patents

Info

Publication number
NL6910859A
NL6910859A NL6910859A NL6910859A NL6910859A NL 6910859 A NL6910859 A NL 6910859A NL 6910859 A NL6910859 A NL 6910859A NL 6910859 A NL6910859 A NL 6910859A NL 6910859 A NL6910859 A NL 6910859A
Authority
NL
Netherlands
Application number
NL6910859A
Other versions
NL148607B (nl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of NL6910859A publication Critical patent/NL6910859A/xx
Publication of NL148607B publication Critical patent/NL148607B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01B—MEASURING LENGTH, THICKNESS OR SIMILAR LINEAR DIMENSIONS; MEASURING ANGLES; MEASURING AREAS; MEASURING IRREGULARITIES OF SURFACES OR CONTOURS
    • G01B13/00—Measuring arrangements characterised by the use of fluids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Emergency Medicine (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
NL696910859A 1968-07-15 1969-07-15 Werkwijze voor het bereiden van geneesmiddelen met antispasmodische en anticholinergische activiteit welke als actief bestanddeel een 3-chinuclidinolester bevatten, aldus bereide gevormde geneesmiddelen, alsmede een werkwijze voor het bereiden van de actieve verbindingen. NL148607B (nl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB33654/68A GB1219606A (en) 1968-07-15 1968-07-15 Quinuclidinol derivatives and preparation thereof

Publications (2)

Publication Number Publication Date
NL6910859A true NL6910859A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1970-01-19
NL148607B NL148607B (nl) 1976-02-16

Family

ID=10355712

Family Applications (1)

Application Number Title Priority Date Filing Date
NL696910859A NL148607B (nl) 1968-07-15 1969-07-15 Werkwijze voor het bereiden van geneesmiddelen met antispasmodische en anticholinergische activiteit welke als actief bestanddeel een 3-chinuclidinolester bevatten, aldus bereide gevormde geneesmiddelen, alsmede een werkwijze voor het bereiden van de actieve verbindingen.

Country Status (9)

Country Link
US (1) US3714357A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AT (1) AT291272B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BE (1) BE735031A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CH (1) CH513174A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE1935751A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FR (1) FR2012964A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GB (1) GB1219606A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NL (1) NL148607B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
SE (1) SE361314B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (78)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2155927A1 (en) * 1971-10-15 1973-05-25 Synthelabo 1-phenylcyclo hexane carboxylic acid esters - with antispasmodic and anticholinergic activity
IT1130997B (it) * 1980-03-19 1986-06-18 D & D Srl Esteri e derivati chinucleidinici di acidi fenossicarbossilici,procedimento per la loro preparazione e relative composizioni farmaceutiche
JPS57500735A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1980-06-03 1982-04-30
US4431627A (en) * 1980-06-03 1984-02-14 Research Corporation Gamma-emitting receptor-binding 3-quinuclidinyl glycolates; methods of preparation thereof and imaging and assay methods utilizing same
US4644003A (en) * 1985-04-03 1987-02-17 Research Corporation 3-quinuclidinol esters, useful as antagonists of muscarinic acetylcholine receptors
GB8923590D0 (en) * 1989-10-19 1989-12-06 Pfizer Ltd Antimuscarinic bronchodilators
DE69132735T2 (de) * 1990-09-06 2002-05-29 Pfizer Inc., New York Anti-muscarin bronchodilatoren
WO1998000138A1 (en) * 1996-07-01 1998-01-08 Sepracor, Inc. Methods and compositions for treating urinary incontinence using enantiomerically enriched (r)-clidinium
EP0938313A4 (en) * 1996-07-01 2000-02-23 Sepracor Inc METHODS AND COMPOSITIONS FOR TREATING URINARY INCONTINENCE WITH ENANTIOMORPHISM-ENRICHED (S) -CLIDINIUM
ES2165768B1 (es) * 1999-07-14 2003-04-01 Almirall Prodesfarma Sa Nuevos derivados de quinuclidina y composiciones farmaceuticas que los contienen.
US7214687B2 (en) 1999-07-14 2007-05-08 Almirall Ag Quinuclidine derivatives and medicinal compositions containing the same
RU2296762C2 (ru) 2000-12-22 2007-04-10 Альмиралль Продесфарма Аг Карбаматы хинуклидина, способы их получения и фармацевтическая композиция на их основе
AU2002238471B2 (en) 2000-12-28 2007-06-28 Almirall, S.A. Quinuclidine derivatives and their use as M3 antagonists
ES2206021B1 (es) * 2002-04-16 2005-08-01 Almirall Prodesfarma, S.A. Nuevos derivados de pirrolidinio.
ES2203327B1 (es) * 2002-06-21 2005-06-16 Almirall Prodesfarma, S.A. Nuevos carbamatos de quinuclidina y composiciones farmaceuticas que los contienen.
ES2204295B1 (es) 2002-07-02 2005-08-01 Almirall Prodesfarma, S.A. Nuevos derivados de quinuclidina-amida.
AR044519A1 (es) 2003-05-02 2005-09-14 Novartis Ag Derivados de piridin-tiazol amina y de pirimidin-tiazol amina
AR044134A1 (es) * 2003-05-02 2005-08-24 Novartis Ag Derivados de quinuclidina, metodo de preparacion y composiciones farmaceuticas.
GB0401334D0 (en) 2004-01-21 2004-02-25 Novartis Ag Organic compounds
ES2239546B1 (es) * 2004-03-15 2006-12-01 Almirall Prodesfarma, S.A. Nuevos esteres de quinuclidina cuaternizados.
GB0411056D0 (en) 2004-05-18 2004-06-23 Novartis Ag Organic compounds
ES2257152B1 (es) * 2004-05-31 2007-07-01 Laboratorios Almirall S.A. Combinaciones que comprenden agentes antimuscarinicos y agonistas beta-adrenergicos.
ES2246170B1 (es) * 2004-07-29 2007-04-01 Almirall Prodesfarma, S.A. Nuevo procedimiento para preparar derivados de carbamato de quinuclidinio.
GT200500281A (es) 2004-10-22 2006-04-24 Novartis Ag Compuestos organicos.
GB0424284D0 (en) 2004-11-02 2004-12-01 Novartis Ag Organic compounds
GB0426164D0 (en) 2004-11-29 2004-12-29 Novartis Ag Organic compounds
GB0507577D0 (en) 2005-04-14 2005-05-18 Novartis Ag Organic compounds
GB0510390D0 (en) 2005-05-20 2005-06-29 Novartis Ag Organic compounds
PL2532679T3 (pl) 2005-10-21 2017-09-29 Novartis Ag Ludzkie przeciwciała przeciwko IL13 i zastosowania terapeutyczne
GB0601951D0 (en) 2006-01-31 2006-03-15 Novartis Ag Organic compounds
BRPI0710573A2 (pt) 2006-04-21 2012-02-28 Novartis Ag compostos orgánicos, usos e processos para a preparação dos referidos compostos, bem como composição farmacêutica compreendendo os mesmos
ES2298049B1 (es) 2006-07-21 2009-10-20 Laboratorios Almirall S.A. Procedimiento para fabricar bromuro de 3(r)-(2-hidroxi-2,2-ditien-2-ilacetoxi)-1-(3-fenoxipropil)-1-azoniabiciclo (2.2.2) octano.
RU2009115954A (ru) 2006-09-29 2010-11-10 Новартис АГ (CH) Пиразолопиримидины в качестве ингибиторов липидной киназы р13к
EP2104535B9 (en) 2007-01-10 2011-06-15 Irm Llc Compounds and compositions as channel activating protease inhibitors
PT2155721E (pt) 2007-05-07 2011-05-09 Novartis Ag Compostos org?nicos
CA2608561A1 (en) * 2007-10-29 2009-04-29 Carl Paluszkiewicz Motorcycle wind deflector accessory support
WO2009074575A2 (en) 2007-12-10 2009-06-18 Novartis Ag Organic compounds
WO2009087224A1 (en) 2008-01-11 2009-07-16 Novartis Ag Pyrimidines as kinase inhibitors
EP2100598A1 (en) 2008-03-13 2009-09-16 Laboratorios Almirall, S.A. Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease
EP2100599A1 (en) 2008-03-13 2009-09-16 Laboratorios Almirall, S.A. Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease
US8268834B2 (en) 2008-03-19 2012-09-18 Novartis Ag Pyrazine derivatives that inhibit phosphatidylinositol 3-kinase enzyme
EP2300010B1 (en) 2008-06-10 2015-03-04 Novartis AG Pyrazine derivatives as epithelial sodium channel blockers
EP2391366B1 (en) 2009-01-29 2012-11-28 Novartis AG Substituted benzimidazoles for the treatment of astrocytomas
US8389526B2 (en) 2009-08-07 2013-03-05 Novartis Ag 3-heteroarylmethyl-imidazo[1,2-b]pyridazin-6-yl derivatives
JP5781510B2 (ja) 2009-08-12 2015-09-24 ノバルティス アーゲー ヘテロ環式ヒドラゾン化合物および癌および炎症の処置のためのそれらの使用
IN2012DN01961A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 2009-08-17 2015-08-21 Intellikine Llc
JP5775871B2 (ja) 2009-08-20 2015-09-09 ノバルティス アーゲー ヘテロ環式オキシム化合物
EP2490687A1 (en) 2009-10-22 2012-08-29 Vertex Pharmaceuticals Incorporated Compositions for treatment of cystic fibrosis and other chronic diseases
US8247436B2 (en) 2010-03-19 2012-08-21 Novartis Ag Pyridine and pyrazine derivative for the treatment of CF
WO2012034095A1 (en) 2010-09-09 2012-03-15 Irm Llc Compounds and compositions as trk inhibitors
US8637516B2 (en) 2010-09-09 2014-01-28 Irm Llc Compounds and compositions as TRK inhibitors
US8372845B2 (en) 2010-09-17 2013-02-12 Novartis Ag Pyrazine derivatives as enac blockers
JP2014505088A (ja) 2011-02-10 2014-02-27 ノバルティス アーゲー Ｃ−ＭＥＴチロシンキナーゼ阻害剤としての［１，２，４］トリアゾロ［４，３−ｂ］ピリダジン化合物
US9127000B2 (en) 2011-02-23 2015-09-08 Intellikine, LLC. Heterocyclic compounds and uses thereof
AU2012220572A1 (en) 2011-02-25 2013-08-29 Irm Llc Compounds and compositions as trk inhibitors
EP2510928A1 (en) 2011-04-15 2012-10-17 Almirall, S.A. Aclidinium for use in improving the quality of sleep in respiratory patients
UY34305A (es) 2011-09-01 2013-04-30 Novartis Ag Derivados de heterociclos bicíclicos para el tratamiento de la hipertensión arterial pulmonar
WO2013038362A1 (en) 2011-09-15 2013-03-21 Novartis Ag 6 - substituted 3 - (quinolin- 6 - ylthio) - [1,2,4] triazolo [4, 3 -a] pyradines as tyrosine kinase
WO2013038373A1 (en) 2011-09-16 2013-03-21 Novartis Ag Pyridine amide derivatives
WO2013038386A1 (en) 2011-09-16 2013-03-21 Novartis Ag Heterocyclic compounds for the treatment of cystic fibrosis
WO2013038381A1 (en) 2011-09-16 2013-03-21 Novartis Ag Pyridine/pyrazine amide derivatives
WO2013038378A1 (en) 2011-09-16 2013-03-21 Novartis Ag Pyridine amide derivatives
WO2013038390A1 (en) 2011-09-16 2013-03-21 Novartis Ag N-substituted heterocyclyl carboxamides
CN104363914A (zh) 2011-11-23 2015-02-18 因特利凯有限责任公司 使用mTOR抑制剂的增强的治疗方案
US8809340B2 (en) 2012-03-19 2014-08-19 Novartis Ag Crystalline form
RU2660354C2 (ru) 2012-04-03 2018-07-05 Новартис Аг Комбинированные продукты, содержащие ингибиторы тирозинкиназ, и их применение
US9073921B2 (en) 2013-03-01 2015-07-07 Novartis Ag Salt forms of bicyclic heterocyclic derivatives
CN105246482A (zh) 2013-03-15 2016-01-13 因特利凯有限责任公司 激酶抑制剂的组合及其用途
BR112016000629B1 (pt) 2013-07-13 2023-10-31 Beijing Showby Pharmaceutical Co., Ltd. Compostos de quinina e isômeros ópticos, método de preparação e utilização médica dos mesmos
TW201605450A (zh) 2013-12-03 2016-02-16 諾華公司 Ｍｄｍ２抑制劑與ＢＲＡＦ抑制劑之組合及其用途
AU2014391605A1 (en) 2014-04-24 2016-10-27 Novartis Ag Amino pyridine derivatives as phosphatidylinositol 3-kinase inhibitors
WO2015162461A1 (en) 2014-04-24 2015-10-29 Novartis Ag Pyrazine derivatives as phosphatidylinositol 3-kinase inhibitors
EA032075B1 (ru) 2014-04-24 2019-04-30 Новартис Аг Производные аминопиразина в качестве ингибиторов фосфатидилинозитол-3-киназы
WO2016011658A1 (en) 2014-07-25 2016-01-28 Novartis Ag Combination therapy
ES2831416T3 (es) 2014-07-31 2021-06-08 Novartis Ag Terapia de combinación de un inhibidor de MET y un inhibidor de EGFR
BR112021024668A2 (pt) 2019-06-10 2022-05-31 Novartis Ag Derivado de piridina e pirazina para o tratamento de fc, dpoc e bronquiectasia
AU2020338971B2 (en) 2019-08-28 2023-11-23 Novartis Ag Substituted 1,3-phenyl heteroaryl derivatives and their use in the treatment of disease
TW202140550A (zh) 2020-01-29 2021-11-01 瑞士商諾華公司 使用抗ｔｓｌｐ抗體治療炎性或阻塞性氣道疾病之方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3252981A (en) * 1963-05-24 1966-05-24 Chemetron Corp Process for benzilic esters

Also Published As

Publication number Publication date
BE735031A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1969-12-01
GB1219606A (en) 1971-01-20
AT291272B (de) 1971-07-12
FR2012964A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1970-03-27
CH513174A (fr) 1971-09-30
US3714357A (en) 1973-01-30
SE361314B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1973-10-29
NL148607B (nl) 1976-02-16
DE1935751A1 (de) 1970-02-26

Similar Documents

Publication Publication Date Title
FR2012964A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU5506869A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU5184069A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU6168869A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU6171569A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU4304568A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU4811568A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU4744468A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BE726602A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BE709095A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BE726948A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BE726793A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BE728001A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BE726487A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BE726325A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BE725153A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BE722901A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BE709496A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BE709484A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BE709479A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BE709446A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BE709435A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BE709415A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BE709320A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BE709319A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Legal Events

Date Code Title Description
V1 Lapsed because of non-payment of the annual fee
NL80 Information provided on patent owner name for an already discontinued patent

Owner name: SOGERAS