NL2000937A1 - Piperidinederivaten. - Google Patents

Piperidinederivaten.

Info

Publication number
NL2000937A1
NL2000937A1 NL2000937A NL2000937A NL2000937A1 NL 2000937 A1 NL2000937 A1 NL 2000937A1 NL 2000937 A NL2000937 A NL 2000937A NL 2000937 A NL2000937 A NL 2000937A NL 2000937 A1 NL2000937 A1 NL 2000937A1
Authority
NL
Netherlands
Prior art keywords
piperidine derivatives
piperidine
derivatives
Prior art date
Application number
NL2000937A
Other languages
English (en)
Other versions
NL2000937C2 (nl
Inventor
Michelle Marie Bruendl
Keri Lynn Greene
Allen Jennings Rex
Scott Edward Lazerwith
Joe Nahra
Patrick Michael O'brien
Kimberly Suzanne Para
Susan Mary Kult Sheehan
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of NL2000937A1 publication Critical patent/NL2000937A1/nl
Application granted granted Critical
Publication of NL2000937C2 publication Critical patent/NL2000937C2/nl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/20Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
    • C07D211/22Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems
NL2000937A 2005-12-20 2007-10-15 Piperidinederivaten. NL2000937C2 (nl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US75184505P 2005-12-20 2005-12-20
US75184505 2005-12-20

Publications (2)

Publication Number Publication Date
NL2000937A1 true NL2000937A1 (nl) 2008-01-11
NL2000937C2 NL2000937C2 (nl) 2008-07-22

Family

ID=38015373

Family Applications (2)

Application Number Title Priority Date Filing Date
NL2000376A NL2000376C2 (nl) 2005-12-20 2006-12-15 Piperidinederivaten.
NL2000937A NL2000937C2 (nl) 2005-12-20 2007-10-15 Piperidinederivaten.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
NL2000376A NL2000376C2 (nl) 2005-12-20 2006-12-15 Piperidinederivaten.

Country Status (12)

Country Link
US (1) US20070142389A1 (nl)
EP (1) EP1966137A2 (nl)
JP (1) JP2009520018A (nl)
AR (1) AR058110A1 (nl)
CA (1) CA2634172A1 (nl)
DO (1) DOP2006000287A (nl)
GT (1) GT200600516A (nl)
NL (2) NL2000376C2 (nl)
PE (1) PE20071005A1 (nl)
TW (1) TW200732304A (nl)
UY (1) UY30029A1 (nl)
WO (1) WO2007072150A2 (nl)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8575364B2 (en) 2008-10-30 2013-11-05 Janssen Pharmaceutica Nv Modulators of serotonin receptor
US8642583B2 (en) 2008-10-30 2014-02-04 Janssen Pharmaceutica Nv Serotonin receptor modulators
DK2358674T3 (da) 2008-11-14 2013-04-08 Theravance Inc Fremgangsmåde til fremstilling af 4-[2-(2-fluorphenoxymethyl)phenyl]piperidinforbindelser
JP5705239B2 (ja) 2010-01-11 2015-04-22 セラヴァンス バイオファーマ アール&ディー アイピー, エルエルシー セロトニンおよびノルエピネフリン再取込みインヒビターとしての1−(2−フェノキシメチルフェニル)ピペラジン化合物
AR089837A1 (es) * 2012-01-31 2014-09-17 Eisai R&D Man Co Ltd Derivado de paroxetina
CN108025002B (zh) * 2015-09-02 2022-05-13 特维娜有限公司 含有六元氮杂杂环的δ阿片受体调节化合物、其使用和制备方法
KR20190117658A (ko) 2017-02-17 2019-10-16 트레베나, 인코포레이티드. 7-원 아자-헤테로고리 함유 델타-오피오이드 수용체 조절 화합물, 및 그의 사용 및 제조 방법
BR112019016827A2 (pt) 2017-02-17 2020-04-07 Trevena Inc compostos moduladores de receptor delta-opioide contendo aza-heterocíclico com 5 membros, métodos de uso e produção dos mesmos
CN111533682B (zh) * 2020-05-29 2022-03-01 清华大学 帕罗西汀及其类似物的制备方法

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1422263A (en) * 1973-01-30 1976-01-21 Ferrosan As 4-phenyl-piperidine compounds
IE45511B1 (en) * 1976-09-01 1982-09-08 Ciba Geigy Ag New derivatives of perhydro-aza-heterocycles and processesfor the production thereof
US4585777A (en) * 1984-02-07 1986-04-29 A/S Ferrosan (-)-Trans-4-(4-fluorophenyl)-3-(4-methoxyphenoxy)methylpiperidine for potentiating 5-HT
EP0190496A3 (en) * 1984-12-13 1987-05-27 Beecham Group Plc Piperidine derivatives having a gastro-intestinal activity
IE66332B1 (en) * 1986-11-03 1995-12-27 Novo Nordisk As Piperidine compounds and their preparation and use
DK231088D0 (da) * 1988-04-28 1988-04-28 Ferrosan As Piperidinforbindelser, deres fremstilling og anvendelse
US5227379A (en) * 1986-11-03 1993-07-13 Novo Nordisk A/S Piperidine compounds and their preparation and use
US5017585A (en) * 1986-11-03 1991-05-21 Novo Nordisk A/S Method of treating calcium overload
IL98757A (en) * 1990-07-18 1997-01-10 Novo Nordisk As Piperidine derivatives their preparation and pharmaceutical compositions containing them
US5808139A (en) * 1992-04-21 1998-09-15 Ligand Pharmaceuticals Incorporated Non-steroid progesterone receptor agonist and antagonist and compounds and methods
US5914328A (en) * 1992-10-09 1999-06-22 Abbott Laboratories Heterocyclic ether compounds useful in controlling neurotransmitter release
ES2201192T3 (es) * 1995-09-07 2004-03-16 F. Hoffmann-La Roche Ag Nuevos 4-(oxialcoxifenil)-3-oxi-piperidinas para el tratamiento de la insuficiencia cardiaca y renal.
US20020151712A1 (en) * 1999-09-14 2002-10-17 Nan-Horng Lin 3-pyrrolidinyloxy-3'-pyridyl ether compounds useful for controlling chemical synaptic transmission
WO2001032178A1 (en) * 1999-10-29 2001-05-10 Novo Nordisk A/S Use of 3,4-substituted piperidines
US20040087795A1 (en) * 2000-07-17 2004-05-06 Borrett Gary Thomas Novel processes for the preparation of 4-phenylpiperidine derivatives
JP2005500371A (ja) * 2001-08-08 2005-01-06 ニューロサーチ、アクティーゼルスカブ 置換されたアミン誘導体及びこれをモノアミン神経伝達物質再取り込み阻害剤として使用する方法

Also Published As

Publication number Publication date
US20070142389A1 (en) 2007-06-21
DOP2006000287A (es) 2007-11-30
NL2000937C2 (nl) 2008-07-22
CA2634172A1 (en) 2007-06-28
TW200732304A (en) 2007-09-01
AR058110A1 (es) 2008-01-23
EP1966137A2 (en) 2008-09-10
GT200600516A (es) 2007-08-21
WO2007072150A2 (en) 2007-06-28
PE20071005A1 (es) 2007-10-24
NL2000376C2 (nl) 2007-10-24
WO2007072150A3 (en) 2008-05-29
JP2009520018A (ja) 2009-05-21
UY30029A1 (es) 2007-07-31
NL2000376A1 (nl) 2007-06-21

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Legal Events

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AD1A A request for search or an international type search has been filed
RD2N Patents in respect of which a decision has been taken or a report has been made (novelty report)

Effective date: 20080320

PD2B A search report has been drawn up
V1 Lapsed because of non-payment of the annual fee

Effective date: 20110701