NL182727C - Werkwijze ter bereiding van een 2-(3-acylamino-4-acylaminothio-2-oxoazetidine-1-yl)-2-(1-methylethenyl)azijnzuur derivaat, alsmede werkwijze ter bereiding van esters van 7-acylamino-3-(acetoxymethyl)cefem-4-carbonzuren. - Google Patents

Werkwijze ter bereiding van een 2-(3-acylamino-4-acylaminothio-2-oxoazetidine-1-yl)-2-(1-methylethenyl)azijnzuur derivaat, alsmede werkwijze ter bereiding van esters van 7-acylamino-3-(acetoxymethyl)cefem-4-carbonzuren.

Info

Publication number
NL182727C
NL182727C NLAANVRAGE7501457,A NL7501457A NL182727C NL 182727 C NL182727 C NL 182727C NL 7501457 A NL7501457 A NL 7501457A NL 182727 C NL182727 C NL 182727C
Authority
NL
Netherlands
Prior art keywords
preparation
eesters
acylethylethylethylethylethenyl
acylaminothio
cefem
Prior art date
Application number
NLAANVRAGE7501457,A
Other languages
English (en)
Dutch (nl)
Other versions
NL182727B (nl
NL7501457A (nl
Inventor
Jan Dr Verwey
Hong Sheng Ir Tan
Original Assignee
Gist Brocades Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gist Brocades Nv filed Critical Gist Brocades Nv
Publication of NL7501457A publication Critical patent/NL7501457A/xx
Publication of NL182727B publication Critical patent/NL182727B/xx
Application granted granted Critical
Publication of NL182727C publication Critical patent/NL182727C/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/46—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with hetero atoms directly attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/02—Preparation
    • C07D501/08—Preparation by forming the ring or condensed ring systems
    • C07D501/10—Preparation by forming the ring or condensed ring systems from compounds containing the penicillin ring system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
    • C07D501/30—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group with the 7-amino-radical acylated by an araliphatic carboxylic acid

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Cephalosporin Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
NLAANVRAGE7501457,A 1974-02-08 1975-02-07 Werkwijze ter bereiding van een 2-(3-acylamino-4-acylaminothio-2-oxoazetidine-1-yl)-2-(1-methylethenyl)azijnzuur derivaat, alsmede werkwijze ter bereiding van esters van 7-acylamino-3-(acetoxymethyl)cefem-4-carbonzuren. NL182727C (nl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB5811/74A GB1483526A (en) 1974-02-08 1974-02-08 Azetidine derivatives

Publications (3)

Publication Number Publication Date
NL7501457A NL7501457A (nl) 1975-08-12
NL182727B NL182727B (nl) 1987-12-01
NL182727C true NL182727C (nl) 1988-05-02

Family

ID=9803053

Family Applications (1)

Application Number Title Priority Date Filing Date
NLAANVRAGE7501457,A NL182727C (nl) 1974-02-08 1975-02-07 Werkwijze ter bereiding van een 2-(3-acylamino-4-acylaminothio-2-oxoazetidine-1-yl)-2-(1-methylethenyl)azijnzuur derivaat, alsmede werkwijze ter bereiding van esters van 7-acylamino-3-(acetoxymethyl)cefem-4-carbonzuren.

Country Status (17)

Country Link
US (1) US4007202A (es)
JP (2) JPS5924991B2 (es)
BE (1) BE825325A (es)
CH (1) CH594661A5 (es)
CS (2) CS189635B2 (es)
DE (1) DE2505280A1 (es)
DK (2) DK152365C (es)
FI (1) FI63748C (es)
FR (1) FR2260584B1 (es)
GB (1) GB1483526A (es)
HU (1) HU172237B (es)
IE (1) IE40636B1 (es)
IT (1) IT1046090B (es)
LU (1) LU71817A1 (es)
NL (1) NL182727C (es)
SE (2) SE429337B (es)
SU (2) SU577979A3 (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1465893A (en) * 1973-02-09 1977-03-02 Gist Brocades Nv I-carboxypropenyl-4-iminothio-azetidine-2-one derivatives methods for their preparation and use
US4046761A (en) * 1974-02-08 1977-09-06 Gist-Brocades N.V. Process for preparing cephalosporin derivatives
US4301278A (en) * 1974-02-26 1981-11-17 Ciba-Geigy Corporation Process for the manufacture of enol derivatives
US4147864A (en) * 1975-02-20 1979-04-03 Ciba-Geigy Corporation Process for the manufacture of 7β-amino-3-cephem-3-ol-4 carboxylic acid compounds
GB2099817B (en) * 1981-04-10 1985-05-15 Otsuka Kagaku Yakuhin Azetidinone derivatives and process for the preparation of the same
JPS5865289A (ja) * 1981-10-14 1983-04-18 Sankyo Co Ltd アゼチジノン誘導体
JPS59164771A (ja) * 1983-03-10 1984-09-17 Otsuka Chem Co Ltd 塩素化アゼチジノン誘導体の製造方法
JPH0487971A (ja) * 1990-07-13 1992-03-19 Mishima Seishi Kk 帯電防止および又は静電気シールド用包装容器
US6383773B2 (en) 1998-04-23 2002-05-07 Massachusetts Institute Of Technology Penicillin conversion

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL204361A (es) * 1955-04-22 1900-01-01
US3843682A (en) * 1972-05-15 1974-10-22 Lilly Co Eli 2-chlorosulfinyl-3-imido-azetedin-4-ones

Also Published As

Publication number Publication date
DK45875A (es) 1975-10-06
FR2260584B1 (es) 1979-02-23
SE7810147L (sv) 1978-09-27
IT1046090B (it) 1980-06-30
DK152365C (da) 1988-08-01
DK446978A (da) 1978-10-06
NL182727B (nl) 1987-12-01
JPS5924991B2 (ja) 1984-06-13
DK152365B (da) 1988-02-22
SU577979A3 (ru) 1977-10-25
BE825325A (fr) 1975-08-07
SE7501375L (es) 1975-08-11
DK151810B (da) 1988-01-04
CS189635B2 (en) 1979-04-30
NL7501457A (nl) 1975-08-12
US4007202A (en) 1977-02-08
DE2505280A1 (de) 1975-08-14
JPS58150598A (ja) 1983-09-07
FI63748C (fi) 1983-08-10
JPS6047277B2 (ja) 1985-10-21
LU71817A1 (es) 1975-06-24
IE40636L (en) 1975-08-08
FR2260584A1 (es) 1975-09-05
SE429337B (sv) 1983-08-29
HU172237B (hu) 1978-07-28
CS189642B2 (en) 1979-04-30
CH594661A5 (es) 1978-01-13
SU656526A3 (ru) 1979-04-05
JPS50108257A (es) 1975-08-26
GB1483526A (en) 1977-08-24
DK151810C (da) 1988-06-06
FI63748B (fi) 1983-04-29
SE427842B (sv) 1983-05-09
IE40636B1 (en) 1979-07-18
FI750346A (es) 1975-08-09

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Legal Events

Date Code Title Description
BA A request for search or an international-type search has been filed
BB A search report has been drawn up
BC A request for examination has been filed
A85 Still pending on 85-01-01
BK Erratum

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V1 Lapsed because of non-payment of the annual fee